Cd2+-induced swelling-contraction dynamics in isolated kidney cortex mitochondria: Role of Ca2+ uniporter, K+ cycling, and protonmotive force

American Journal of Physiology - Cell Physiology

Volumn 289, Issue 3 58-3, 2005, Pages

  Lee, Wing Kee ^a,b   Spielmann, Malte ^a   Bork, Ulrich ^a   Thévenod, Frank ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Bongkrekic acid; Cyclosporin A; Lanthanum; Ru360; Ruthenium red

Indexed keywords

BONGKREKIC ACID; CADMIUM; CALCIUM ION; CYCLOSPORIN A; LANTHANUM; LITHIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM ION; POTASSIUM PROTON EXCHANGE PROTEIN; QUININE; RU 360; RUTHENIUM RED; SODIUM CHLORIDE; UNCLASSIFIED DRUG; BUFFER; CALCIUM CHANNEL; MITOCHONDRIAL CALCIUM UNIPORTER; POTASSIUM; PROTON;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MALE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTON MOTIVE FORCE; RAT; STRUCTURE ACTIVITY RELATION; ANIMAL; DRUG EFFECT; METABOLISM; MITOCHONDRION; MITOCHONDRION SWELLING; OSMOTIC PRESSURE; PH; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

CINCHONA PUBESCENS;

ANIMALS; BUFFERS; CADMIUM; CALCIUM CHANNELS; HYDROGEN-ION CONCENTRATION; KIDNEY CORTEX; MALE; MITOCHONDRIA; MITOCHONDRIAL SWELLING; OSMOTIC PRESSURE; POTASSIUM; POTASSIUM CHLORIDE; POTASSIUM-HYDROGEN ANTIPORTERS; PROTONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 23944473594     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00049.2005     Document Type: Article

References (59)

1. Akao M, Ohler A, O'Rourke B, and Marbán E. Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells. Circ Res 88: 1267-1275, 2001.
2. Almofti MR, Ichikawa T, Yamashita K, Terada H, and Shinohara Y. Silver ion induces a cyclosporine A-insensitive permeability transition in rat liver mitochondria and release of apoptogenic cytochrome c. J Biochem (Tokyo) 134: 43-49, 2003.
3. Al-Nasser IA. Cadmium hepatotoxicity and alterations of the mitochondrial function. J Toxicol Clin Toxicol 38: 407-413, 2000.
4. Beavis AD, Brannan RD, and Garlid KD. Swelling and contraction of the mitochondrial matrix. I. a structural interpretation of the relationship between light scattering and matrix volume. J Biol Chem 260: 13424-13433, 1985.
5. Bernardi P. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol Rev 79: 1127-1155, 1999.
6. Bernardi P, Petronilli V, Di Lisa F, and Forte M. A mitochondrial perspective on cell death. Trends Biochem Sci 26: 112-117, 2001.
7. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
8. Cortese JD, Voglino AL, and Hackenbrock CR. Multiple conformations of physiological membrane-bound cytochrome c. Biochemistry 37: 6402-6409, 1998.
9. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 341: 233-249, 1999.
10. 2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. Biochem J 255: 357-360, 1988.
11. ATP channel is modulated by calcium and nitric oxide: a patch-clamp approach. Biochim Biophys Acta 1656: 46-56, 2004.
12. Du C, Fang M, Li Y, Li L, and Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42, 2000.
13. Eliseev RA, Gunter KK, and Gunter TE. Bcl-2 sensitive mitochondrial potassium accumulation and swelling in apoptosis. Mitochondrion 1: 361-370, 2002.
14. Eliseev RA, Salter JD, Gunter KK, and Gunter TE. Bcl-2 and tBid proteins counter-regulate mitochondrial potassium transport. Biochim Biophys Acta 1604: 1-5, 2003.
15. Emaus RK, Grunwald R, and Lemasters JJ. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta 850: 436-448, 1986.
16. Friberg L, Elinder CG, Kjellström T, and Nordberg GF. Cadmium and Health: A Toxicological and Epidemiological Approach, Boca Raton, FL: CRC, 1986.
17. + cycle. Biochim Biophys Acta 1606: 23-41, 2003.
18. ATP channel as a receptor for potassium channel openers. J Biol Chem 271: 8796-8799, 1996.
19. Gogvadze V, Robertson JD, Enoksson M, Zhivotovsky B, and Orrenius S. Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition. Biochem J 378: 213-217, 2004.
20. 2+-independent mechanisms that are regulated by Bax. J Biol Chem 276: 19066-19071, 2001.
21. 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidylprolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase. Biochem J 268: 153-160, 1990.
22. Halestrap AP, Kerr PM, Javadov S, and Woodfield KY. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1366: 79-94, 1998.
23. Halestrap AP, Quinlan PT, Whipps DE, and Armston AE. Regulation of the mitochondrial matrix volume in vivo and in vitro: the role of calcium. Biochem J 236: 779-787, 1986.
24. He L and Lemasters JJ. Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett 512: 1-7, 2002.
25. + channel in the mitochondrial inner membrane. Nature 352: 244-247, 1991.
26. Jaburek M, Yarov-Yarovoy V, Paucek P, and Garlid KD. State-dependent inhibition of the mitochondrial KATP channel by glyburide and 5-hydroxydecanoate. J Biol Chem 273: 13578-13582, 1998.
27. Jarup L, Berglund M, Blinder CG, Nordberg G, and Vahter M. Health effects of cadmium exposure: a review of the literature and a risk estimate. Scand J Work Environ Health 24, Suppl 1: 1-51, 1998.
28. + exchange in mitochondria as monitored by BCECF fluorescence. FEBS Lett 251: 49-52, 1989.
29. Kirichok Y, Krapivinsky G, and Clapham DE. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427: 360-364, 2004.
30. Kjellström T. Exposure and accumulation of cadmium in populations from Japan, the United States, and Sweden. Environ Health Perspect 28: 169-197, 1979.
31. Klaassen CD (ed.). Casarett and Doull's Toxicology: The Basic Science of Poisons (5th ed.). New York: McGraw-Hill, 1999.
32. Kroemer G. Mitochondrial control of apoptosis: an introduction. Biochem Biophys Res Commun 304: 433-435, 2003.
33. 2+ uniporter. Am J Physiol Renal Physiol 288: F27-F39, 2005.
34. 2-induced nephrotoxicity indicates that renal injury is not mediated by the CdMT complex. Toxicol Sci 46: 197-203, 1998.
35. Liu X, Kim CN, Yang J, Jemmerson R, and Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86: 147-157, 1996.
36. Martinou JC and Green DR. Breaking the mitochondrial barrier. Nat Rev Mol Cell Biol 2: 63-67, 2001.
37. 2+ transport across the inner membrane of mammalian mitochondria. Eur J Biochem 192: 239-244, 1990.
38. + exchangers in rat liver mitochondria. J Biol Chem 257: 9252-9254, 1982.
39. Ott M, Robertson JD, Gogvadze V, Zhivotovsky B, and Orrenius S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci USA 99: 1259-1263, 2002.
40. Robertson JD, Gogvadze V, Zhivotovsky B, and Orrenius S. Distinct pathways for stimulation of cytochrome c release by etoposide. J Biol Chem 275: 32438-32443, 2000.
41. Robertson JD and Orrenius S. Molecular mechanisms of apoptosis induced by cytotoxic chemicals. Crit Rev Toxicol 30: 609-627, 2000.
42. Schonfeld P, Gerke S, Bohnensack R, and Wojtczak L. Stimulation of potassium cycling in mitochondria by long-chain fatty acids. Biochim Biophys Acta 1604: 125-133, 2003.
43. 2+ from liver mitochondria by nonesterified long-chain fatty acids in alkaline media. Arch Biochem Biophys 403: 16-24, 2002.
44. Shimizu S, Narita M, and Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399: 483-487, 1999.
45. Shimizu S and Tsujimoto Y. Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity. Proc Natl Acad Sci USA 97: 577-582, 2000.
46. 2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line. Biochem Biophys Res Commun 257: 549-554, 1999.
47. Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM, and Kroemer G. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397: 441-446, 1999.
48. Takebayashi S, Jimi S, Segawa M, and Kiyoshi Y. Cadmium induces osteomalacia mediated by proximal tubular atrophy and disturbances of phosphate reabsorption: a study of 11 autopsies. Pathol Res Pract 196: 653-663, 2000.
49. Thévenod F. Nephrotoxicity and the proximal tubule: insights from cadmium. Nephron Physiol 93: p87-p93, 2003.
50. +-ATPase through proteasomal and endo-/lysosomal proteolytic pathways. FASEB J 13: 1751-1761, 1999.
51. Thévenod F, Friedmann JM, Katsen AD, and Hauser IA. Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-κβ activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. J Biol Chem 275: 1887-1896, 2000.
52. Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ, and Vaux DL. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102: 43-53, 2000.
53. Von Ahsen O, Renken C, Perkins G, Kluck RM, Bossy-Wetzel E, and Newmeyer DD. Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release. J Cell Biol 150: 1027-1036, 2000.
54. Wang Y, Fang J, Leonard SS, and Rao KM. Cadmium inhibits the electron transfer chain and induces reactive oxygen species. Free Radic Biol Med 36: 1434-1443, 2004.
55. Wedeen RP and De Broe ME. Heavy metals and the kidney. In: Oxford Textbook of Clinical Nephrology (2nd ed.), edited by Davison AM, Cameron JS, Grünfeld JP, Kerr DNS, Ritz E, and Winearls CQ. Oxford, UK: Oxford University Press. 1998, vol. 2, p. 1175-1189.
56. + channels in the cardiac inner mitochondrial membrane. Science 298: 1029-1033, 2002.
57. Zalups RK and Ahmad S. Molecular handling of cadmium in transporting epithelia. Toxicol Appl Pharmacol 186: 163-188, 2003.
58. Zalups RK and Koropatnick J (eds.). Molecular Biology and Toxicology of Metals. New York: Taylor & Francis, 2000.
59. Zazueta C, Sosa-Torres ME, Correa F, and Garza-Ortiz A. Inhibitory properties of ruthenium amine complexes on mitochondrial calcium uptake. J Bioenerg Biomembr 31: 551-557, 1999.