Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 24, 1996, Pages 14100-14105

  Pincus, Steven M ^a   Mulligan, Thomas ^b   Iranmanesh, Ali ^c   Gheorghiu, Sylvia ^b   Godschalk, Michael ^b   Veldhuis, Johannes D ^d  

^a Medical College of Virginia ^*  (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d NATIONAL SCIENCE FOUNDATION   (United States)

Author keywords

aging; approximate entropy; pulsatility; reproduction; variable lag process

Indexed keywords

GROWTH HORMONE; LUTEINIZING HORMONE; TESTOSTERONE;

ADULT; AGED; AGING; BODY WEIGHT; CELL ACTIVITY; CONFERENCE PAPER; ENTROPY; GROWTH HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REPRODUCTION; SMOKING HABIT; SPERMATOGENESIS; STATISTICAL ANALYSIS; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE RELEASE;

EID: 0030450771     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.24.14100     Document Type: Article

References (40)

1. Bremner, W. J., Vitiello, M. V. & Prinz, P. N. (1983) J. Clin. Endocrinol. Metab. 56, 1278-1281.
2. Harman, S. M. & Tsitouras, P. D. (1980) J. Clin. Endocrinol. Metab. 51, 35-40.
3. Nankin, H. R. & Calkins, J. H. (1986) J. Clin. Endocrinol. Metab. 63, 1418-1420.
4. Vermeulen, A., Ruben, R. & Verdonck, L. (1972) J. Clin. Endocrinol. Metab. 34, 730-735.
5. Warner, B. A., Dufau, M. L. & Santen, R. J. (1985) J. Clin. Endocrinol. Metab. 60, 263-268.
6. Zumoff, B., Strain, G. W., Kream, J., O'Connor, J., Rosenfeld, R. S., Levin, J. & Fukushima, D. K. (1982) J. Clin. Endocrinol. Metab. 54, 534-538.
7. Deslypere, J. P., Kaufman, J. M., Vermeulen, T., Vogelaers, D., Vandalem, J. L. & Vermeulen, A. (1987) J. Clin. Endocrinol. Metab. 64, 68-73.
8. Mulligan, T., Iranmanesh, A., Gheorghiu, S., Godschalk, M. & Veldhuis, J. D. (1995) J. Clin. Endocrinol. Metab. 80, 3025-3031.
9. Veldhuis, J. D., Urban, R. J., Lizarralde, G., Johnson, M. L. & Iranmanesh, A. (1992) J. Clin. Endocrinol. Metab. 75, 707-713.
10. Vermeulen, A., Deslypere, J. P. & Kaufman, J. M. (1989) J. Clin. Endocrinol. Metab. 68, 68-72.
11. Pincus, S. M. (1991) Proc. Natl. Acad. Sci. USA 88, 2297-2301.
12. Pincus, S. M. & Singer, B. H. (1996) Proc. Natl. Acad. Sci. USA 93, 2083-2088.
13. Fleisher, L. A., Pincus, S. M. & Rosenbaum, S. H. (1993) Anesthesiology 78, 683-692.
14. Pincus, S. M., Cummins, T. R. & Haddad, G. G. (1993) Am. J. Physiol. 264, R638-R646.
15. Pincus, S. M., Gladstone, I. M. & Ehrenkranz, R. A. (1991) J. Clin. Monit. 7, 335-345.
16. Pincus, S. M. & Huang, W.-M. (1992) Commun. Stat.-Theory Methods 21, 3061-3077.
17. Pincus, S. M. & Keefe, D. L. (1992) Am. J. Physiol. 262, E741-E754.
18. Pincus, S. M. & Viscarello, R. R. (1992) Obstet. Gynecol. 79, 249-255.
19. Urban, R. J., Evans, W. S., Rogol, A. D., Kaiser, D. L., Johnson, M. L. & Veldhuis, J. D. (1988) Endocr. Rev. 9, 3-37.
20. Pincus, S. M. (1994) Math. Biosci. 122, 161-181.
21. Hartman, M. L., Pincus, S. M., Johnson, M. L., Matthews, D. H., Faunt, L. M., Vance, M. L., Thorner, M. O. & Veldhuis, J. D. (1994) J. Clin. Invest. 94, 1277-1288.
22. Siragy, H. M., Vieweg, W. V. R., Pincus, S. M. & Veldhuis, J. D. (1995) J. Clin. Endocrinol. Metab. 80, 28-34.
23. Pincus, S. M., Gevers, E. F., Robinson, I. C. A. F., van den Berg, G., Roelfsema, F., Hartman, M. L. & Veldhuis, J. D. (1996) Am. J. Physiol. 270, E107-E115.
24. Veldhuis, J. D., Liem, A. Y., South, S., Weltman, A., Weltman, J., Clemmons, D. A., Abbott, R., Mulligan, T., Johnson, M. L., Pincus, S., Straume, M. & Iranmanesh, A. (1995) J. Clin. Endocrinol. Metab. 80, 3209-3222.
25. Pincus, S. M. & Goldberger, A. L. (1994) Am. J. Physiol. 266, H1643-H1656.
26. Pincus, S. M. (1992) Proc. Natl. Acad. Sci. USA 89, 4432-4436.
27. Touitou, Y. (1995) Horm. Res. 43, 12-19.
28. Urban, R. J., Veldhuis, J. D., Blizzard, R. M. & Dufau, M. L. (1988) J. Clin. Invest. 81, 1020-1029.
29. Copinschi, G. & van Cauter, E. (1995) Horm. Res. 43, 20-24.
30. Ho, K. Y., Evans, W. S., Blizzard, R. M., Veldhuis, J. D., Merriam, G. R., Samojlik, E., Furlanetto, R., Rogol, A. D., Kaiser, D. L. & Thorner, M. O. (1987) J. Clin. Endocrinol. Metab. 64, 51-58.
31. Iranmanesh, A., Lizarralde, G. & Veldhuis, J. D. (1991) J. Clin. Endocrinol. Metab. 73, 1081-1088.
32. Tenover, J. S., Matsumoto, A. M., Clifton, D. K. & Bremner, W. J. (1988) J. Gerontol 43, M163-M169.
33. van Coevorden, A., Mockel, J., Laurent, E., Kerkhofs, M., L'Hermite-Baleriaux, M., Decoster, C., Neve, P. & van Cauter, E. (1991) Am. J. Physiol. 260, E651-E661.
34. Chatfield, C. (1989) The Analysis of Time Series: An introduction (Chapman & Hall, London), 4th Ed.
35. Thomson, D. J. (1990) Philos. Trans. R. Soc. London A 330, 601-616.
36. Kuo, C., Lindberg, C. & Thomson, D. J. (1990) Nature (London) 343, 709-714.
37. Box, G. E. P. & Jenkins, G. M. (1976) Time Series Analysis, Forecasting and Control (Holden-Day, San Francisco).
38. Bremaud, J. P. (1981) Point Processes and Queues: Martingale Dynamics (Springer, New York).
39. Aldous, D. (1989) Probability Approximations via the Poisson Clumping Heuristic (Springer, Berlin).
40. Veldhuis, J. D., Johnson, M. L. & Seneta, E. (1991) J. Clin. Endocrinol. Metab. 73, 569-576