Efficacy of olanzapine: An overview of pivotal clinical trials

Journal of Clinical Psychiatry

Volumn 58, Issue SUPPL. 10, 1997, Pages 7-12

  Beasley Jr , Charles M ^a   Tollefson, Gary D ^a   Tran, Pierre V ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; OLANZAPINE; PLACEBO; SEROTONIN 2 RECEPTOR;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RECEPTOR BINDING; EXTRAPYRAMIDAL SYMPTOM; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NEGATIVE SYNDROME; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHIZOPHRENIA;

ACUTE DISEASE; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; DOUBLE-BLIND METHOD; HALOPERIDOL; HUMANS; MALE; MULTICENTER STUDIES; PIRENZEPINE; PLACEBOS; PSYCHIATRIC STATUS RATING SCALES; RANDOMIZED CONTROLLED TRIALS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; TREATMENT OUTCOME;

EID: 1842330245     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Baldwin DS, Montgomery SA. First clinical experience with olanzapine (LY 170053): results of an open-label safety and dose-ranging study in patients with schizophrenia. Int Clin Psychopharmacol 1995;10:239-244
2. Beasley CM Jr, Sanger T, Satterlee W, et al. Olanzapine vs placebo: results of a double-blind, fixed-dose olanzapine trial. Psychopharmacology (Berl) 1996;124:159-167
3. Beasley CM Jr, Tollefson G, Tran P, et al. Olanzapine versus placebo and haloperidol: acute phase results of the North American double-blind olanzapine trial. Neuropsychopharmacology 1996;14:111-123
4. Beasley CM Jr, Hamilton SH, Crawford AM, et al, and the Olanzapine E003 Study Group. Olanzapine versus haloperidol: acute phase results of the international double-blind olanzapine trial. Eur Neuropsychopharmacol. In press
5. Tollefson GD, Beasley CM Jr, Tran PV, et al. Olanzapine versus halopendol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997;154:457-465
6. Tran PV, Beasley CM, Dellva MA, et al. Long term efficacy and safety of olanzapine. Presented at the 34th annual meeting of the American College of Neuropsychopharmacology; Dec 11-15, 1995; San Juan, Puerto Rico
7. Tollefson GD, Sanger TM. Negative symptoms: a path analytic approach to a double-blind, placebo-and haloperidol-controlled climcal trial with olanzapine. Am J Psychiatry 1997;154:466-474