Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8, and H-9

Journal of Molecular Neuroscience

Volumn 7, Issue 1, 1996, Pages 65-76

  Cagnoli, Cinzia M ^a   Kharlamov, Elena ^a   Atabay, Cagla ^a   Uz, Tolga ^a   Manev, Hari ^a,b  

^a ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Actinomycin D; Cerebellar granule cells; Chelerythrine; Okadaic acid; Phosphorylation; PKC; Programmed cell death; Staurosporine

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ENZYME INHIBITOR; ISOQUINOLINE DERIVATIVE; N (2 (METHYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N (2 AMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(METHYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; N-(2-AMINOETHYL)-5-ISOQUINOLINESULFONAMIDE; OKADAIC ACID; PHOSPHATASE; PROTEIN KINASE C; STAUROSPORINE; SULFONAMIDE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CEREBELLUM; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; NERVE CELL; RAT; SPRAGUE DAWLEY RAT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBELLUM; ENZYME INHIBITORS; ISOQUINOLINES; NEURONS; OKADAIC ACID; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; STAUROSPORINE; SULFONAMIDES;

EID: 0030093869     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02736849     Document Type: Article

References (7)

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