A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 281, Issue 6 50-6, 2001, Pages

  Zuideveld, Klaas P ^a   Maas, Hugo J ^a   Treijtel, Nicoline ^a   Hulshof, Joost ^b   Van Der Graaf, Piet H ^a   Peletier, Lambertus A ^c   Danhof, Meindert ^a,d  

^a LEIDEN UNIVERSITY   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

5 hydroxytryptamine1A receptor; Pharmacokinetic pharmacodynamic modeling; R 8 hydroxy 2 (di n propylamino)tetralin; S 8 hydroxy 2 (di n propylamino)tetralin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 1A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEAT LOSS; HYPOTHERMIA; MALE; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NONHUMAN; OSCILLATION; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0035658567     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.2001.281.6.r2059     Document Type: Article

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