Pharmacokinetic-pharmacodynamic modelling of the hypothermic and corticosterone effects of the 5-HT1A receptor agonist flesinoxan

European Journal of Pharmacology

Volumn 445, Issue 1-2, 2002, Pages 43-54

  van Gestel, Aukje ^a   Danhof, Meindert ^a   Peletier, Lambertus A ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

5 HT1A receptor; Corticosterone; Flesinoxan; Handling; Hypothermia; Pharmacokinetic pharmacodynamic modelling

Indexed keywords

CORTICOSTERONE; FLESINOXAN;

ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG EFFECT; DRUG POTENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHERMIA; MALE; MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; TELEMETRY;

ANIMALS; BODY TEMPERATURE; CORTICOSTERONE; HANDLING (PSYCHOLOGY); HYPOTHERMIA; MALE; PIPERAZINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS;

EID: 0037036227     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01665-5     Document Type: Article

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