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Volumn 39, Issue 2, 2005, Pages 206-214

Melatonin restores the cytochrome oxidase reactivity in the nodose ganglia of acute hypoxic rats

Author keywords

Cytochrome oxidase; Hypoxia; Image analysis; Melatonin; Nitric oxide; Nodose ganglion; Quantitative histochemistry

Indexed keywords

CYTOCHROME C OXIDASE; MELATONIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

EID: 23744456452     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2005.00238.x     Document Type: Article
Times cited : (16)

References (56)
  • 1
    • 0027340070 scopus 로고
    • O2 deprivation in the central nervous system: On mechanisms of neuronal response, differential sensitivity and injury
    • HADDAD GG, JIANG C. O2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog Neurobiol 1993; 40:277-318.
    • (1993) Prog Neurobiol , vol.40 , pp. 277-318
    • Haddad, G.G.1    Jiang, C.2
  • 2
  • 3
    • 0037298872 scopus 로고    scopus 로고
    • Upregulation of NMDA receptor and neuronal NADPH-d/NOS expression in the no-dose ganglion of acute hypoxic rats
    • CHANG HM, LIAO WC, LUE JH et al. Upregulation of NMDA receptor and neuronal NADPH-d/NOS expression in the no-dose ganglion of acute hypoxic rats. J Chem Neuroanat 2003; 25:137-147.
    • (2003) J Chem Neuroanat , vol.25 , pp. 137-147
    • Chang, H.M.1    Liao, W.C.2    Lue, J.H.3
  • 4
    • 0019848111 scopus 로고
    • The pathogenesis of irreversible cell injury in ischemia
    • FARBER JL, CHIEN KR, MITTNACHT S Jr. The pathogenesis of irreversible cell injury in ischemia. Am J Pathol 1981; 102:271-281.
    • (1981) Am J Pathol , vol.102 , pp. 271-281
    • Farber, J.L.1    Chien, K.R.2    Mittnacht Jr., S.3
  • 5
    • 0024333640 scopus 로고
    • Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain
    • IKONOMIDOU C, PRICE MT, MOSINGER JL et al. Hypobaric-ischemic conditions produce glutamate-like cytopathology in infant rat brain. J Neurosci 1989; 9:1693-1700.
    • (1989) J Neurosci , vol.9 , pp. 1693-1700
    • Ikonomidou, C.1    Price, M.T.2    Mosinger, J.L.3
  • 6
    • 0025350138 scopus 로고
    • Experimental biology of cerebral hypoxia-ischemia: Relation to perinatal brain damage
    • VANNUCCI RC. Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. Pediatr Res 1990; 27:317-326.
    • (1990) Pediatr Res , vol.27 , pp. 317-326
    • Vannucci, R.C.1
  • 7
    • 0030182852 scopus 로고    scopus 로고
    • The effects of in vivo hypoxia on brain injury
    • PEARIGEN P, GWINN R, SIMON RP. The effects of in vivo hypoxia on brain injury. Brain Res 1996; 725:184-191.
    • (1996) Brain Res , vol.725 , pp. 184-191
    • Pearigen, P.1    Gwinn, R.2    Simon, R.P.3
  • 8
    • 0035815571 scopus 로고    scopus 로고
    • Energetic metabolism in mouse cerebral cortex during chronic hypoxia
    • CÁCEDA R, GAMBOA JL, BOERO JA et al. Energetic metabolism in mouse cerebral cortex during chronic hypoxia. Neurosci Lett 2001; 301:171-174.
    • (2001) Neurosci Lett , vol.301 , pp. 171-174
    • Cáceda, R.1    Gamboa, J.L.2    Boero, J.A.3
  • 9
    • 0026560558 scopus 로고
    • Role of glutamate as the central neurotransmitter in the hypoxic ventilatory response
    • ANG RC, HOOP B, KAZEMI H. Role of glutamate as the central neurotransmitter in the hypoxic ventilatory response. J Appl Physiol 1992; 72:1480-1487.
    • (1992) J Appl Physiol , vol.72 , pp. 1480-1487
    • Ang, R.C.1    Hoop, B.2    Kazemi, H.3
  • 10
    • 0028180636 scopus 로고
    • In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia
    • MIZUSAWA A, OGAWA H, KIKUCHI Y et al. In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia. J Physiol 1994; 478:55-66.
    • (1994) J Physiol , vol.478 , pp. 55-66
    • Mizusawa, A.1    Ogawa, H.2    Kikuchi, Y.3
  • 11
    • 0031935189 scopus 로고    scopus 로고
    • NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat
    • OHTAKE PJ, TORRES JE, GOZAL YM et al. NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat. J Appl Physiol 1998; 84:853-861.
    • (1998) J Appl Physiol , vol.84 , pp. 853-861
    • Ohtake, P.J.1    Torres, J.E.2    Gozal, Y.M.3
  • 12
    • 0028856368 scopus 로고
    • NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: Implication for cell death
    • GUNASEKAR PG, KANTHASAMY AG, BOROWITZ JL et al. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J Neurochem 1995; 65:2016-2021.
    • (1995) J Neurochem , vol.65 , pp. 2016-2021
    • Gunasekar, P.G.1    Kanthasamy, A.G.2    Borowitz, J.L.3
  • 13
    • 0032956184 scopus 로고
    • NMDA receptor-mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus
    • ZANELLI SA, NUMAGAMI Y, MCGOWAN JE et al. NMDA receptor-mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus. Neurochem Res 1995; 24:437-446.
    • (1995) Neurochem Res , vol.24 , pp. 437-446
    • Zanelli, S.A.1    Numagami, Y.2    Mcgowan, J.E.3
  • 14
    • 10644287654 scopus 로고    scopus 로고
    • Nitric oxide, hypoxia and brain inflammation
    • MANDER P, BROWN GC. Nitric oxide, hypoxia and brain inflammation. Biochem Soc Trans 2004; 32:1068-1069.
    • (2004) Biochem Soc Trans , vol.32 , pp. 1068-1069
    • Mander, P.1    Brown, G.C.2
  • 15
    • 0032504710 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • BEAL MF. Mitochondrial dysfunction in neurodegenerative diseases. Biochem Biophys Acta 1998; 1366:211-223.
    • (1998) Biochem Biophys Acta , vol.1366 , pp. 211-223
    • Beal, M.F.1
  • 16
    • 0032749848 scopus 로고    scopus 로고
    • Mitochondrial physiology and pathology: Concepts or programmed death of organelles, cells and organisms
    • SKULACHEV VP. Mitochondrial physiology and pathology: concepts or programmed death of organelles, cells and organisms. Mol Aspects Med 1999; 20:139-184.
    • (1999) Mol Aspects Med , vol.20 , pp. 139-184
    • Skulachev, V.P.1
  • 18
    • 0025322981 scopus 로고
    • Structure and function of cytochrome c oxidase
    • CAPALDI RA. Structure and function of cytochrome c oxidase. Annu Rev Biochem 1990; 59:569-596.
    • (1990) Annu Rev Biochem , vol.59 , pp. 569-596
    • Capaldi, R.A.1
  • 19
    • 0031744885 scopus 로고    scopus 로고
    • Pathways for electron tunneling in cytochrome c oxidase
    • REGAN JJ, RAMIREZ BE, WINKLER JR et al. Pathways for electron tunneling in cytochrome c oxidase. J Bioenerg Biomembr 1998; 30:35-39.
    • (1998) J Bioenerg Biomembr , vol.30 , pp. 35-39
    • Regan, J.J.1    Ramirez, B.E.2    Winkler, J.R.3
  • 20
    • 0024561501 scopus 로고
    • Cytochrome oxidase: An endogenous metabolic marker for neuronal activity
    • WONG-RILEY MTT. Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci 1989; 12:94-101.
    • (1989) Trends Neurosci , vol.12 , pp. 94-101
    • Wong-Riley, M.T.T.1
  • 21
    • 0017863146 scopus 로고
    • Changes in endogenous enzymatic reactivity to DAB induced by neuronal inactivity
    • WONG-RILEY MTT, MERZENICH MM, LEAKE PA. Changes in endogenous enzymatic reactivity to DAB induced by neuronal inactivity. Brain Res 1978; 141:185-192.
    • (1978) Brain Res , vol.141 , pp. 185-192
    • Wong-Riley, M.T.T.1    Merzenich, M.M.2    Leake, P.A.3
  • 22
    • 0018358930 scopus 로고
    • Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry
    • WONG-RILEY MTT. Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res 1979; 171:11-28.
    • (1979) Brain Res , vol.171 , pp. 11-28
    • Wong-Riley, M.T.T.1
  • 23
    • 0001222430 scopus 로고
    • Histochemical changes in cytochrome oxidase of cortical barrels after vibrissal removal in neonatal and adult mice
    • WONG-RILEY MTT, WELT C. Histochemical changes in cytochrome oxidase of cortical barrels after vibrissal removal in neonatal and adult mice. Proc Natl Acad Sci U S A 1980; 77:2333-2337.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 2333-2337
    • Wong-Riley, M.T.T.1    Welt, C.2
  • 24
    • 0019918228 scopus 로고
    • Histochemical localization of cytochrome oxidase in the hippocampus: Correlation with specific neuronal types and afferent pathways
    • KAGEYAMA GH, WONG-RILEY MTT. Histochemical localization of cytochrome oxidase in the hippocampus: correlation with specific neuronal types and afferent pathways. Neuroscience 1982; 10:2337-2361.
    • (1982) Neuroscience , vol.10 , pp. 2337-2361
    • Kageyama, G.H.1    Wong-Riley, M.T.T.2
  • 25
    • 0026604449 scopus 로고
    • Cytochrome oxidase activity in vagal and glossopharyngeal visceral sensory neurons of the rat: Effect of peripheral axotomy
    • ICHIKAWA H, HELKE CJ. Cytochrome oxidase activity in vagal and glossopharyngeal visceral sensory neurons of the rat: effect of peripheral axotomy. Brain Res 1992; 578:311-316.
    • (1992) Brain Res , vol.578 , pp. 311-316
    • Ichikawa, H.1    Helke, C.J.2
  • 26
    • 0027953323 scopus 로고
    • Axotomy-induced changes in cytochrome oxidase activity in the cat trochlear nucleus
    • IANNUZZELLI PG, WANG XH, WANG Y et al. Axotomy-induced changes in cytochrome oxidase activity in the cat trochlear nucleus. Brain Res 1994; 637:267-272.
    • (1994) Brain Res , vol.637 , pp. 267-272
    • Iannuzzelli, P.G.1    Wang, X.H.2    Wang, Y.3
  • 27
    • 0029904154 scopus 로고    scopus 로고
    • Decreased rat brain cytochrome oxidase activity after prolonged hypoxia
    • LAMANNA JC, KUTINA-NELSON KL, HRITZ MA et al. Decreased rat brain cytochrome oxidase activity after prolonged hypoxia. Brain Res 1996; 720:1-6.
    • (1996) Brain Res , vol.720 , pp. 1-6
    • Lamanna, J.C.1    Kutina-Nelson, K.L.2    Hritz, M.A.3
  • 28
    • 0002979059 scopus 로고
    • Melatonin: A potent, endogenous hydroxyl radical scavenger
    • TAN DX, CHEN LD, POEGGELER B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1993; 1:57-60.
    • (1993) Endocr J , vol.1 , pp. 57-60
    • Tan, D.X.1    Chen, L.D.2    Poeggeler, B.3
  • 29
    • 0030914428 scopus 로고    scopus 로고
    • Pharmacological actions of melatonin in oxygen radical pathophysiology
    • REITER RJ, TANG L, GARCIA JJ et al. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 1997; 60:2255-2271.
    • (1997) Life Sci , vol.60 , pp. 2255-2271
    • Reiter, R.J.1    Tang, L.2    Garcia, J.J.3
  • 30
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the central nervous system: Protection by melatonin
    • REITER RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56:359-384.
    • (1998) Prog Neurobiol , vol.56 , pp. 359-384
    • Reiter, R.J.1
  • 31
    • 12244304145 scopus 로고    scopus 로고
    • The chemistry of melatonin's interaction with reactive species
    • ALLEGRA M, REITER RJ, TAN DX et al. The chemistry of melatonin's interaction with reactive species. J Pineal Res 2003; 34:1-10.
    • (2003) J Pineal Res , vol.34 , pp. 1-10
    • Allegra, M.1    Reiter, R.J.2    Tan, D.X.3
  • 32
    • 0008236684 scopus 로고    scopus 로고
    • Oxidative stress in diabetic rats induced by streptozotocin: Protective effects of melatonin
    • MONTILLA P, VARGAS J, TÚNEZ I et al. Oxidative stress in diabetic rats induced by streptozotocin: protective effects of melatonin. J Pineal Res 1998; 25:94-100.
    • (1998) J Pineal Res , vol.25 , pp. 94-100
    • Montilla, P.1    Vargas, J.2    Túnez, I.3
  • 33
    • 0033451946 scopus 로고    scopus 로고
    • Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and Parkinsonism
    • REITER RJ, CABRERA J, SAINZ RM et al. Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and Parkinsonism. Ann N Y Acad Sci 1999; 890:471-485.
    • (1999) Ann N Y Acad Sci , vol.890 , pp. 471-485
    • Reiter, R.J.1    Cabrera, J.2    Sainz, R.M.3
  • 34
    • 0037378182 scopus 로고    scopus 로고
    • The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
    • CHEUNG RTF. The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion. J Pineal Res 2003; 34:153-160.
    • (2003) J Pineal Res , vol.34 , pp. 153-160
    • Cheung, R.T.F.1
  • 35
    • 0343962623 scopus 로고    scopus 로고
    • Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury
    • CHANG HM, LING EA, LUE JH et al. Melatonin attenuates neuronal NADPH-d/NOS expression in the hypoglossal nucleus of adult rats following peripheral nerve injury. Brain Res 2000; 873:243-251.
    • (2000) Brain Res , vol.873 , pp. 243-251
    • Chang, H.M.1    Ling, E.A.2    Lue, J.H.3
  • 36
    • 0006295841 scopus 로고    scopus 로고
    • Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo
    • MARTIN M, MACÍS M, ESCAMES G et al. Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo. J Pineal Res 2000; 28:242-248.
    • (2000) J Pineal Res , vol.28 , pp. 242-248
    • Martin, M.1    MacÍs, M.2    Escames, G.3
  • 38
    • 85012748571 scopus 로고
    • Image analysis techniques for quantification of immunohistochemical staining in the nervous system
    • Conn PM, ed. Academic Press, San Diego, CA
    • SMOLEN AJ. Image analysis techniques for quantification of immunohistochemical staining in the nervous system. In: Methods in Neuroscience: Quantitative and Qualitative Microscopy. Conn PM, ed. Academic Press, San Diego, CA, 1990; pp. 208-229.
    • (1990) Methods in Neuroscience: Quantitative and Qualitative Microscopy , pp. 208-229
    • Smolen, A.J.1
  • 39
    • 0022587546 scopus 로고
    • Cytochrome oxidase staining reveals functional organization of monkey somatosensory thalamus
    • JONES EG, HENDRY SHC, BRANDON C. Cytochrome oxidase staining reveals functional organization of monkey somatosensory thalamus. Exp Brain Res 1986; 62:438-442.
    • (1986) Exp Brain Res , vol.62 , pp. 438-442
    • Jones, E.G.1    Hendry, S.H.C.2    Brandon, C.3
  • 40
    • 0021836964 scopus 로고
    • Mitochondrial abnormalities in cortical dendrites from patients with Alzheimer's disease
    • SARAIVA AA, BORGES MM, MADEIRA MD et al. Mitochondrial abnormalities in cortical dendrites from patients with Alzheimer's disease. J Submicrosc Cytol 1985; 17:459-464.
    • (1985) J Submicrosc Cytol , vol.17 , pp. 459-464
    • Saraiva, A.A.1    Borges, M.M.2    Madeira, M.D.3
  • 41
    • 0026531834 scopus 로고
    • Biological roles of nitric oxide
    • SNYDER SH, BREDT DS. Biological roles of nitric oxide. Sci Am 1992; 226:68-77.
    • (1992) Sci Am , vol.226 , pp. 68-77
    • Snyder, S.H.1    Bredt, D.S.2
  • 42
    • 0032898838 scopus 로고    scopus 로고
    • Nitric oxide and cell death
    • MURPHY MP. Nitric oxide and cell death. Biochim Biophys Acta 1999; 1411:401-414.
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 401-414
    • Murphy, M.P.1
  • 43
    • 0032947296 scopus 로고    scopus 로고
    • Nitric oxide and mitochondrial respiration
    • BROWN GC. Nitric oxide and mitochondrial respiration. Biochim Biophys Acta 1999; 1411:351-369.
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 351-369
    • Brown, G.C.1
  • 44
    • 0036162636 scopus 로고    scopus 로고
    • Nitric oxide and cytochrome oxidase: Substrate, inhibitor or effector?
    • COOPER CE. Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector? Trends Biochem Sci 2002; 27:33-39.
    • (2002) Trends Biochem Sci , vol.27 , pp. 33-39
    • Cooper, C.E.1
  • 45
    • 0037370387 scopus 로고    scopus 로고
    • Nitric oxide and cytochrome oxidase: Reaction mechanisms from the enzyme to the cell
    • SARTI P, GIUFFRE A, BARONE MC et al. Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell. Free Rad Biol Med 2003; 34:509-520.
    • (2003) Free Rad Biol Med , vol.34 , pp. 509-520
    • Sarti, P.1    Giuffre, A.2    Barone, M.C.3
  • 46
    • 1642472818 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin gallate attenuates the neuronal NADPH-d/NOS expression in the nodose ganglion of acute hypoxic rats
    • WEI IH, Wu YC, WEN CY et al. Green tea polyphenol (-)-epigallocatechin gallate attenuates the neuronal NADPH-d/NOS expression in the nodose ganglion of acute hypoxic rats. Brain Res 2004; 999:73-80.
    • (2004) Brain Res , vol.999 , pp. 73-80
    • Wei, I.H.1    Wu, Y.C.2    Wen, C.Y.3
  • 47
    • 0031827904 scopus 로고    scopus 로고
    • Protective effect of melatonin in a model of traumatic brain injury in mice
    • MESENGE C, MARGAILL I, VERRECCHIA C et al. Protective effect of melatonin in a model of traumatic brain injury in mice. J Pineal Res 1998; 25:41-46.
    • (1998) J Pineal Res , vol.25 , pp. 41-46
    • Mesenge, C.1    Margaill, I.2    Verrecchia, C.3
  • 48
    • 1642440103 scopus 로고    scopus 로고
    • Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine in the mouse nigrostriatum
    • THOMAS B, MOHANAKUMAR KP. Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine in the mouse nigrostriatum. J Pineal Res 2004; 36:25-32.
    • (2004) J Pineal Res , vol.36 , pp. 25-32
    • Thomas, B.1    Mohanakumar, K.P.2
  • 49
    • 0027763443 scopus 로고
    • Nuclear localization of melatonin in different mammalian tissues. Immunocytochemical and radioimmunoassay evidence
    • MENÉNDEZ-PELÁEZ A, POEGGELER B, REITER RJ et al. Nuclear localization of melatonin in different mammalian tissues. Immunocytochemical and radioimmunoassay evidence. J Cell Biochem 1993; 53:373-382.
    • (1993) J Cell Biochem , vol.53 , pp. 373-382
    • Menéndez-Peláez, A.1    Poeggeler, B.2    Reiter, R.J.3
  • 50
    • 0033382517 scopus 로고    scopus 로고
    • Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative damage
    • GARCIA JJ, REITER RJ, PIE J et al. Role of pinoline and melatonin in stabilizing hepatic microsomal membranes against oxidative damage. J Bioenerg Biomem 1999; 31:609-616.
    • (1999) J Bioenerg Biomem , vol.31 , pp. 609-616
    • Garcia, J.J.1    Reiter, R.J.2    Pie, J.3
  • 51
    • 0342894684 scopus 로고    scopus 로고
    • Melatonin is a scavenger of peroxynitrite
    • GILAD E, CUZZOCREA S, ZINGARELLI B et al. Melatonin is a scavenger of peroxynitrite. Life Sci 1997; 60:169-174.
    • (1997) Life Sci , vol.60 , pp. 169-174
    • Gilad, E.1    Cuzzocrea, S.2    Zingarelli, B.3
  • 52
    • 0034564392 scopus 로고    scopus 로고
    • Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
    • TAN DX, MANCHESTER LC, REITER RJ et al. Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free Rad Biol Med 2000; 29:1177-1185.
    • (2000) Free Rad Biol Med , vol.29 , pp. 1177-1185
    • Tan, D.X.1    Manchester, L.C.2    Reiter, R.J.3
  • 53
    • 0030930937 scopus 로고    scopus 로고
    • Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin
    • POZO D, REITER RJ, CALVO JR et al. Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin. J Cell Biochem 1997; 65:430-442.
    • (1997) J Cell Biochem , vol.65 , pp. 430-442
    • Pozo, D.1    Reiter, R.J.2    Calvo, J.R.3
  • 54
    • 0029934729 scopus 로고    scopus 로고
    • Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidant enzymes
    • ANTOLÍN I, RODRIGUEZ C, SAINZ RM et al. Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes. FASEB J 1996; 10:882-890.
    • (1996) FASEB J , vol.10 , pp. 882-890
    • Antolín, I.1    Rodriguez, C.2    Sainz, R.M.3
  • 55
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • RODRIGUEZ C, MAYO JC, SAINZ RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36:1-9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 56
    • 0034846595 scopus 로고    scopus 로고
    • Axotomy along with hypoxia enhances the neuronal NADPH-d/NOS expression in lower brain stem motor neurons of adult rats
    • CHANG HM, LUE JH, WEN CY et al. Axotomy along with hypoxia enhances the neuronal NADPH-d/NOS expression in lower brain stem motor neurons of adult rats. Exp Neurol 2001; 171:116-126.
    • (2001) Exp Neurol , vol.171 , pp. 116-126
    • Chang, H.M.1    Lue, J.H.2    Wen, C.Y.3


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