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Volumn 1, Issue 3, 2004, Pages 321-327

Mechanisms underlying type I diabetes

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65; GLUTEN; INSULIN; MONOCLONAL ANTIBODY CD3; RECOMBINANT ENZYME;

EID: 23744445819     PISSN: 17406765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmec.2004.11.015     Document Type: Review
Times cited : (9)

References (46)
  • 1
    • 0029610841 scopus 로고
    • Genetics of autoimmune disease
    • Merriman, T.R. et al. (1995) Genetics of autoimmune disease. Curr. Opin. Immunol. 7, 786-792
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 786-792
    • Merriman, T.R.1
  • 2
    • 0036080178 scopus 로고    scopus 로고
    • Environmental factors in the etiology of type 1 diabetes
    • Akerblom, H.K. et al. (2002) Environmental factors in the etiology of type 1 diabetes. Am. J. Med. Genet. 115, 18-29
    • (2002) Am. J. Med. Genet. , vol.115 , pp. 18-29
    • Akerblom, H.K.1
  • 3
    • 0024478081 scopus 로고
    • Genetics of IDDM: Evidence for complex inheritance with HLA
    • Risch, N. (1989) Genetics of IDDM: evidence for complex inheritance with HLA. Genet. Epidemiol. 6, 143-148
    • (1989) Genet. Epidemiol. , vol.6 , pp. 143-148
    • Risch, N.1
  • 4
    • 1642443489 scopus 로고    scopus 로고
    • Type 1 diabetes: Recent developments
    • Devendra, D. et al. (2004) Type 1 diabetes: recent developments. Br. Med. J. 328, 750-754
    • (2004) Br. Med. J. , vol.328 , pp. 750-754
    • Devendra, D.1
  • 5
    • 0037328895 scopus 로고    scopus 로고
    • Immunologic endocrine disorders
    • Devendra, D. et al. (2003) Immunologic endocrine disorders. J. Allergy Clin. Immunol. 111 (2 Suppl.), S624-S636
    • (2003) J. Allergy Clin. Immunol. , vol.111 , Issue.2 SUPPL.
    • Devendra, D.1
  • 6
    • 2942738825 scopus 로고    scopus 로고
    • The emerging role of the CTLA-4 gene in autoimmune endocrinopathies
    • Vaidya, B. et al. (2004) The emerging role of the CTLA-4 gene in autoimmune endocrinopathies. Eur. J. Endocrinol. 150, 619-626
    • (2004) Eur. J. Endocrinol. , vol.150 , pp. 619-626
    • Vaidya, B.1
  • 7
    • 0038345163 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes
    • Bassuny, W.M. et al. (2003) A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes. Immunogenetics 55, 149-156
    • (2003) Immunogenetics , vol.55 , pp. 149-156
    • Bassuny, W.M.1
  • 8
    • 0041931076 scopus 로고    scopus 로고
    • Foxp3 and natural regulatory T cells: Key to a cell lineage?
    • Ramsdell, F. (2003) Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity 19, 165-168
    • (2003) Immunity , vol.19 , pp. 165-168
    • Ramsdell, F.1
  • 9
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot, J.D. et al. (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4, 330-336
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1
  • 10
    • 0034235827 scopus 로고    scopus 로고
    • Twins: Mirrors of the immune system
    • Salvetti, M. et al. (2000) Twins: mirrors of the immune system. Immunol. Today 21, 342-347
    • (2000) Immunol. Today , vol.21 , pp. 342-347
    • Salvetti, M.1
  • 11
    • 0036274909 scopus 로고    scopus 로고
    • Antiinfection immunity and autoimmunity
    • Zinkernagel, R.M. (2002) Antiinfection immunity and autoimmunity. Ann. N. Y. Acad. Sci. 958, 3-6
    • (2002) Ann. N. Y. Acad. Sci. , vol.958 , pp. 3-6
    • Zinkernagel, R.M.1
  • 12
    • 1242270574 scopus 로고    scopus 로고
    • Induction, acceleration or prevention of autoimmunity by molecular mimicry
    • Christen, U. et al. (2004) Induction, acceleration or prevention of autoimmunity by molecular mimicry. Mol. Immunol. 40, 1113-1120
    • (2004) Mol. Immunol. , vol.40 , pp. 1113-1120
    • Christen, U.1
  • 13
    • 2942517532 scopus 로고    scopus 로고
    • Coxsackie B virus serology and type 1 diabetes mellitus: A systematic review of published case-control studies
    • Green, J. et al. (2004) Coxsackie B virus serology and type 1 diabetes mellitus: a systematic review of published case-control studies. Diabet. Med 21, 507-514
    • (2004) Diabet. Med , vol.21 , pp. 507-514
    • Green, J.1
  • 14
    • 0026623232 scopus 로고
    • A fifty-year follow-up of congenital rubella
    • McIntosh, E.D. et al. (1992) A fifty-year follow-up of congenital rubella. Lancet 340, 414-415
    • (1992) Lancet , vol.340 , pp. 414-415
    • McIntosh, E.D.1
  • 15
    • 1842483423 scopus 로고    scopus 로고
    • Childhood vaccination and type 1 diabetes
    • Hviid, A. et al. (2004) Childhood vaccination and type 1 diabetes. N. Engl. J. Med. 350, 1398-1404
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1398-1404
    • Hviid, A.1
  • 16
    • 0041324953 scopus 로고    scopus 로고
    • Humoral beta-cell autoimmunity is rare in patients with the congenital rubella syndrome
    • Viskari, H. et al. (2003) Humoral beta-cell autoimmunity is rare in patients with the congenital rubella syndrome. Clin. Exp. Immunol. 133, 378-383
    • (2003) Clin. Exp. Immunol. , vol.133 , pp. 378-383
    • Viskari, H.1
  • 17
    • 0036889147 scopus 로고    scopus 로고
    • Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: Inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
    • Tracy, S. et al. (2002) Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence. J. Virol. 76, 12097-12111
    • (2002) J. Virol. , vol.76 , pp. 12097-12111
    • Tracy, S.1
  • 18
    • 9244250319 scopus 로고    scopus 로고
    • Graves' hyperthyroidism and the hygiene hypothesis in a mouse model
    • Nagayama, Y. et al. (2004) Graves' hyperthyroidism and the hygiene hypothesis in a mouse model. Endocrinology 145, 5075-5079
    • (2004) Endocrinology , vol.145 , pp. 5075-5079
    • Nagayama, Y.1
  • 19
    • 4043170040 scopus 로고    scopus 로고
    • Inhibition of experimental asthma by indoleamine 2,3-dioxygenase
    • Hayashi, T. et al. (2004) Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J. Clin. Invest. 114, 270-279
    • (2004) J. Clin. Invest. , vol.114 , pp. 270-279
    • Hayashi, T.1
  • 20
    • 0033575754 scopus 로고    scopus 로고
    • Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes
    • Fossati, G. et al. (1999) Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes. J. Exp. Med. 190, 577-583
    • (1999) J. Exp. Med. , vol.190 , pp. 577-583
    • Fossati, G.1
  • 21
    • 0036913215 scopus 로고    scopus 로고
    • Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
    • Frigerio, S. et al. (2002) Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat. Med. 8, 1414-1420
    • (2002) Nat. Med. , vol.8 , pp. 1414-1420
    • Frigerio, S.1
  • 22
    • 0346366978 scopus 로고    scopus 로고
    • Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease
    • Christen, U. et al. (2003) Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease. J. Immunol. 171, 6838-6845
    • (2003) J. Immunol. , vol.171 , pp. 6838-6845
    • Christen, U.1
  • 23
    • 85047689596 scopus 로고    scopus 로고
    • Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient
    • Christen, U. et al. (2004) Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient. J. Clin. Invest. 113, 74-84
    • (2004) J. Clin. Invest. , vol.113 , pp. 74-84
    • Christen, U.1
  • 24
    • 0035653672 scopus 로고    scopus 로고
    • The role of Fas ligand in immune privilege
    • Green, D.R. et al. (2001) The role of Fas ligand in immune privilege. Nat. Rev. Mol. Cell. Biol. 2, 917-924
    • (2001) Nat. Rev. Mol. Cell. Biol. , vol.2 , pp. 917-924
    • Green, D.R.1
  • 25
    • 0034987866 scopus 로고    scopus 로고
    • Expression of human Fas ligand on mouse beta islet cells does not induce insulitis but is insufficient to confer immune privilege for islet grafts
    • Hsu, P.N. et al. (2001) Expression of human Fas ligand on mouse beta islet cells does not induce insulitis but is insufficient to confer immune privilege for islet grafts. J. Biomed. Sci. 8, 262-269
    • (2001) J. Biomed. Sci. , vol.8 , pp. 262-269
    • Hsu, P.N.1
  • 26
    • 0030842535 scopus 로고    scopus 로고
    • Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction
    • Kang, S.M. et al. (1997) Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat. Med. 3, 738-743
    • (1997) Nat. Med. , vol.3 , pp. 738-743
    • Kang, S.M.1
  • 27
    • 1442276961 scopus 로고    scopus 로고
    • Virally induced inflammation triggers fratricide of Fas-ligand-expressing beta-cells
    • Christen, U. et al. (2004) Virally induced inflammation triggers fratricide of Fas-ligand-expressing beta-cells. Diabetes 53, 591-596
    • (2004) Diabetes , vol.53 , pp. 591-596
    • Christen, U.1
  • 28
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • Kagi, D. et al. (1997) Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J. Exp. Med. 186, 989-997
    • (1997) J. Exp. Med. , vol.186 , pp. 989-997
    • Kagi, D.1
  • 29
    • 0029942839 scopus 로고    scopus 로고
    • Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity
    • Kagi, D. et al. (1996) Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity. J. Exp. Med. 183, 2143-2152
    • (1996) J. Exp. Med. , vol.183 , pp. 2143-2152
    • Kagi, D.1
  • 30
    • 0033755202 scopus 로고    scopus 로고
    • Virus-induced autoimmune diabetes: Most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes
    • Seewaldt, S. et al. (2000) Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes. Diabetes 49, 1801-1809
    • (2000) Diabetes , vol.49 , pp. 1801-1809
    • Seewaldt, S.1
  • 31
    • 0035313059 scopus 로고    scopus 로고
    • IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death
    • Suk, K. et al. (2001) IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death. J. Immunol. 166, 4481-4489
    • (2001) J. Immunol. , vol.166 , pp. 4481-4489
    • Suk, K.1
  • 32
    • 0036116272 scopus 로고    scopus 로고
    • Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice
    • Greeley, S.A. et al. (2002) Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat. Med. 8, 399-402
    • (2002) Nat. Med. , vol.8 , pp. 399-402
    • Greeley, S.A.1
  • 33
    • 0033564970 scopus 로고    scopus 로고
    • I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice
    • Noorchashm, H. et al. (1999) I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice. J. Immunol. 163, 743-750
    • (1999) J. Immunol. , vol.163 , pp. 743-750
    • Noorchashm, H.1
  • 34
    • 0035807589 scopus 로고    scopus 로고
    • Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency
    • Martin, S. et al. (2001) Development of type 1 diabetes despite severe hereditary B-lymphocyte deficiency. N. Engl. J. Med. 345, 1036-1040
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1036-1040
    • Martin, S.1
  • 35
    • 0347990607 scopus 로고    scopus 로고
    • Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes
    • Koczwara, K. et al. (2004) Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 53, 1-4
    • (2004) Diabetes , vol.53 , pp. 1-4
    • Koczwara, K.1
  • 36
    • 0037113979 scopus 로고    scopus 로고
    • Immunologic and genetic factors in type 1 diabetes
    • Notkins, A.L. (2002) Immunologic and genetic factors in type 1 diabetes. J. Biol. Chem. 277, 43545-43548
    • (2002) J. Biol. Chem. , vol.277 , pp. 43545-43548
    • Notkins, A.L.1
  • 37
    • 0347949511 scopus 로고    scopus 로고
    • Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient
    • Banga, J.P. et al. (2004) Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient. Clin. Exp. Immunol. 135, 74-84
    • (2004) Clin. Exp. Immunol. , vol.135 , pp. 74-84
    • Banga, J.P.1
  • 38
    • 0033980502 scopus 로고    scopus 로고
    • Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts co-expressing TPO and MHC class II
    • Guo, J. et al. (2000) Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts co-expressing TPO and MHC class II. Clin. Exp. Immunol. 119, 38-46
    • (2000) Clin. Exp. Immunol. , vol.119 , pp. 38-46
    • Guo, J.1
  • 39
    • 0037198420 scopus 로고    scopus 로고
    • Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
    • Herold, K.C. et al. (2002) Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N. Engl. J. Med. 346, 1692-1698
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1692-1698
    • Herold, K.C.1
  • 40
    • 2142770174 scopus 로고    scopus 로고
    • CD3 antibody treatment stimulates the functional capability of regulatory T cells
    • discussion 286-290
    • Chatenoud, L. (2003) CD3 antibody treatment stimulates the functional capability of regulatory T cells. Novartis Found. Symp. 252, 279-286 (discussion 286-290)
    • (2003) Novartis Found. Symp. , vol.252 , pp. 279-286
    • Chatenoud, L.1
  • 41
    • 0022348847 scopus 로고
    • Anti-thymocyte globulin and prednisone immunotherapy of recent onset type 1 diabetes mellitus
    • Eisenbarth, G.S. et al. (1985) Anti-thymocyte globulin and prednisone immunotherapy of recent onset type 1 diabetes mellitus. Diabetes Res. 2, 271-276
    • (1985) Diabetes Res. , vol.2 , pp. 271-276
    • Eisenbarth, G.S.1
  • 42
    • 3042554098 scopus 로고    scopus 로고
    • Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system
    • Mathieu, C. et al. (2004) Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system. J. Steroid Biochem. Mol. Biol. 89-90, 449-452
    • (2004) J. Steroid Biochem. Mol. Biol. , vol.89-90 , pp. 449-452
    • Mathieu, C.1
  • 43
    • 4043060025 scopus 로고    scopus 로고
    • A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development
    • Giarratana, N. et al. (2004) A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development. J. Immunol. 173, 2280-2287
    • (2004) J. Immunol. , vol.173 , pp. 2280-2287
    • Giarratana, N.1
  • 44
    • 3142672131 scopus 로고    scopus 로고
    • Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus - A new surrogate measure of non-progression?
    • Schatz, D. et al. (2004) Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus - a new surrogate measure of non-progression? Pediatr. Diabetes 5, 72-79
    • (2004) Pediatr. Diabetes , vol.5 , pp. 72-79
    • Schatz, D.1
  • 45
    • 0035944844 scopus 로고    scopus 로고
    • Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): A randomised, double-blind, phase II trial
    • Raz, I. et al. (2001) Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. Lancet 358, 1749-1753
    • (2001) Lancet , vol.358 , pp. 1749-1753
    • Raz, I.1
  • 46
    • 0036300542 scopus 로고    scopus 로고
    • Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide
    • Alleva, D.G. et al. (2002) Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide. Diabetes 51, 2126-2134
    • (2002) Diabetes , vol.51 , pp. 2126-2134
    • Alleva, D.G.1


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