Inducible nitric oxide synthase, but not xanthine oxidase, is highly expressed in interstitial pneumonias and granulomatous diseases of human lung

American Journal of Clinical Pathology

Volumn 117, Issue 1, 2002, Pages 132-142

  Lakari, Essi ^a   Soini, Ylermi ^a   Säily, Marjaana ^a   Koistinen, Pirjo ^a   Pääkkö, Paavo ^a   Kinnula, Vuokko L ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Allergic alveolitis; Antioxidant; e NOS; i NOS; Interstitial pneumonia; Lung; Oxygen radical; Sarcoidosis; Xanthine oxidase

Indexed keywords

NITRIC OXIDE SYNTHASE; XANTHINE OXIDASE;

ADULT; AGED; ALLERGIC PNEUMONITIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DESQUAMATION; ENZYME LOCALIZATION; FEMALE; FIBROSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; INTERSTITIAL PNEUMONIA; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG BIOPSY; LUNG GRANULOMATOSIS; LUNG LAVAGE; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOIDOSIS;

ADULT; ALVEOLITIS, EXTRINSIC ALLERGIC; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; SARCOIDOSIS, PULMONARY; UP-REGULATION; XANTHINE OXIDASE;

EID: 0036142953     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/W7T9-HW9V-V94B-R9KM     Document Type: Article

References (35)

1. Oxidative damage and fibrogenesis
2. Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification
3. Sarcoidosis
4. Biology of disease: Generation and disposal of reactive oxygen metabolites in the lung
5. Nitric oxide synthase in human and rat lung: Immunocytochemical and histochemical localization
6. Continuous nitric oxide synthase by inducible nitric oxide synthase in normal airway epithelium in vivo
7. Expression of inducible nitric oxide synthase in human lung epithelial cells
8. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells
9. Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
10. The biology of nitrogen oxides in the airways
11. Increased expression of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: Effect of inhaled glucocorticoid
12. Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis
13. Expression of inducible nitric oxide synthase in rat pulmonary Cryptococcus neoformans granulomas
14. In vivo expression of monokine and inducible nitric oxide synthase in experimentally induced pulmonary granulomatous inflammation
15. Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats
16. Expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions
17. Expressional control of the "constitutive" isoforms of nitric oxide synthase (NOS I and NOS III)
18. Biology of disease: Free radicals and tissue injury
19. - forming NADPH oxidase of phagocytes: Nature, mechanisms of activation and function
20. Oxygen-derived free radicals in postischemic tissue injury
21. Assessment of xanthine oxidase in human lung and lung transplantation
22. Xanthine oxidoreductase gene expression and enzyme activity in developing human tissues
23. Cellular expression of xanthine oxidoreductase protein in normal human tissues
24. Organ distribution and molecular forms of human xanthine dehydrogenase/xanthine oxidase protein
25. Measuring repeatability and validity of histological diagnosis: A brief review with some practical examples
26. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes
27. Cloning and expression in vitro of human xanthine dehydrogenase/oxidase
28. Molecular cloning and characterization of human endothelial nitric oxide synthase
29. 1
30. B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity
31. Reactive oxygen and nitrogen intermediates increase transforming growth factorbeta1 release from human epithelial alveolar cells through two different mechanisms
32. Up-regulation of inducible nitric oxide synthase in fibroblasts parallels the onset and progression of fibrosis in an experimental model of post-transplant obliterative airway disease
33. 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
34. Nitric oxide levels in exhaled air and inducible nitric oxide synthase immunolocalization in pulmonary sarcoidosis