Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-β in vitro and in interstitial lung diseases in vivo

Human Pathology

Volumn 35, Issue 8, 2004, Pages 1000-1007

  Peltoniemi, Mirva ^a   Kaarteenaho Wiik, Riitta ^a   Säily, Marjaana ^a   Sormunen, Raija ^a   Pääkkö, Paavo ^a   Holmgren, Arne ^b   Soini, Ylermi ^a   Kinnula, Vuokko L ^c,d  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

GCS; glutamylcysteine synthetase; antioxidant; ASK I; ELF; epithelial lining fluid; fibrosis; glutaredoxin; glutaredoxin 1; glutathione; Grx1; GSH; IPF; sarcoidosis; TGF ; transforming growth factor; transforming growth factor

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC PNEUMONITIS; ARTICLE; BRONCHUS MUCOSA; CELL SPECIFICITY; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INTERSTITIAL LUNG DISEASE; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; PROTEIN EXPRESSION; SARCOIDOSIS;

BLOTTING, WESTERN; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; LUNG; LUNG DISEASES, INTERSTITIAL; MACROPHAGES, ALVEOLAR; MALE; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; OXIDOREDUCTASES; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3843142866     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2004.04.009     Document Type: Article

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