4-Alkylated homoibotenic acid (HIBO) analogues: Versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes

Neuropharmacology

Volumn 49, Issue SUPPL., 2005, Pages 114-119

  Madsen, Ulf ^a   Pickering, Darryl S ^a   Nielsen, Birgitte ^a   Bräuner Osborne, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

AMPA receptors; GluR5; iGluRs; mGluRs; Receptor selectivity

Indexed keywords

AMPA RECEPTOR; BUTYL HOMOIBOTENIC ACID; ETHYL HOMOIBOTENIC ACID; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; GLUTAMATE RECEPTOR 4; GLUTAMATE RECEPTOR 5; IBOTENIC ACID; IONOTROPIC RECEPTOR; ISOBUTYL HOMOIBOTENIC ACID; ISOPENTYL HOMOIBOTENIC ACID; ISOPROPYL HOMOIBOTENIC ACID; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; METHYL HOMOIBOTENIC ACID; PROPYL HOMOIBOTENIC ACID; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BINDING; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; IBOTENIC ACID; INSECTS; PROTEIN BINDING; PROTEIN SUBUNITS; RADIOLIGAND ASSAY; RATS; RECEPTORS, AMPA; RECEPTORS, METABOTROPIC GLUTAMATE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRITIUM;

EID: 23644448756     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2005.05.007     Document Type: Article

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