Selective antagonists at group I metabotropic glutamate receptors: Synthesis and molecular pharmacology of 4-aryl-3-isoxazolol amino acids

Journal of Medicinal Chemistry

Volumn 45, Issue 4, 2002, Pages 988-991

  Kromann, Hasse ^a   Sløk, Frank A ^a   Stensbøl, Tine B ^a   Bräuner Osborne, Hans ^a   Madsen, Ulf ^a   Krogsgaard Larsen, Povl ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3 (3 HYDROXY 5 ISOXAZOLYL)PROPIONIC ACID; AMINO ACID DERIVATIVE; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; IBOTENIC ACID; LIGAND; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROPIONIC ACID DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHOLINERGIC RECEPTOR BLOCKING; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RAT;

ANIMALS; BRAIN; CHO CELLS; CRICETINAE; CYCLIC AMP; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; HYDROLYSIS; ISOXAZOLES; PHOSPHATIDYLINOSITOLS; RADIOLIGAND ASSAY; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037075138     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010443t     Document Type: Article

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