Human S15a Expression Is Upregulated by Hepatitis B Virus X Protein

Molecular Carcinogenesis

Volumn 40, Issue 1, 2004, Pages 34-46

  Lian, Zhaorui ^a   Liu, Jie ^a   Li, Li ^a,b   Li, Xianxing ^b   Tufan, N Lale Satiroglu ^a,e   Wu, Meng Chao ^c   Wang, Hong Yang ^c   Arbuthnot, Patrick ^d   Kew, Michael ^d   Feitelson, Mark A ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^e PAMUKKALE UNIVERSITY   (Turkey)

Author keywords

Hepatitis B x antigen; Hepatocarcinogenesis; Ribosomal protein; Translation

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; HEPATITIS B ANTIGEN; HEPATITIS B VIRUS X ANTIGEN; MESSENGER RNA; RIBOSOME PROTEIN; RIBOSOME PROTEIN S15A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASE PAIRING; CARCINOGENESIS; CELL CYCLE; CELL GROWTH; COLONY FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA ISOLATION; RNA TRANSLATION; SCID MOUSE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CLONING, MOLECULAR; COLONY-FORMING UNITS ASSAY; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATITIS B ANTIGENS; HUMANS; IN SITU HYBRIDIZATION; LIVER; LIVER NEOPLASMS; MICE; MICE, NUDE; MICE, SCID; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEINS; SUBTRACTION TECHNIQUE; TRANS-ACTIVATORS; UP-REGULATION;

HEPATITIS B VIRUS;

EID: 2342575611     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.20012     Document Type: Article

References (47)

1. Beasley RP, Hwang LY. Epidemiology of hepatocellular carcinoma. In: Vyas GN, Dienstag JL, Hoofnagle JH, editors. Viral hepatitis and liver disease. New York: Grune & Stratton, Inc; 1984. pp 209-224.
2. Chen HS, Kaneko S, Girones R, et al. The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks. J Virol 1993;67:1218-1226.
3. Nakatake H, Chisaka O, Yamamoto S, Matsubara K, Koshy R. Effect of X protein on transactivation of HBV promoters and on viral replication. Virology 1993;195:305-314.
4. Miyaki M, Sato C, Gotanda T, et al. Integration of region X of hepatitis B virus genome in human primary hepatocellular carcinomas propagated in nude mice. J Gen Virol 1986;67:1449-1454.
5. Diamantis ID, McGandy CE, Chen TJ, Liaw YF, Gudat F, Bianchi L. Hepatitis B X-gene expression in hepatocellular carcinoma. J Hepatol 1992;15:400-403.
6. Wang W, London WT, Lega L, Feitelson MA. Hepatitis B x antigen in liver from carrier patients with chronic hepatitis and cirrhosis. Hepatology 1991;14:29-37.
7. Rossner MT. Hepatitis B virus X-gene product: A promiscuous transcriptional activator. J Med Virol 1992;36:101-117.
8. Feitelson MA, Duan LX. Hepatitis B virus x antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. Am J Pathol 1997;150:1141-1157.
9. Henkler F, Koshy R. Hepatitis B virus transcriptional activators: Mechanisms and possible role in oncogenesis. J Viral Hepat 1996;3:109-121.
10. Wang XW, Hussain SP, Huo TI, Wu CG, Forgues M, Hofseth U, Brechot C, Harris CC. Molecular pathogenesis of human hepatocellular carcinoma. Toxicology 2002;181-182:43-47.
11. Madden CR, Slagle BL. Stimulation of cellular proliferation by hepatitis B virus X protein. Disease Markers 2001;17:153-157.
12. Lee YH, Yun Y. HBx protein of hepatitis B virus activates Jak1-STAT signaling. J Biol Chem 1998;273:25510-25515.
13. Klein NP, Schneider RJ. Activation of src family kinases by hepatitis B virus HBx protein and coupled signaling to ras. Mol Cell Biol 1997;17:6427-6436.
14. Shih WL, Kuo ML, Chuang SE, Cheng AL, Doong SL. Hepatitis B virus X protein inhibits transforming growth factor-beta-induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway. J Biol Chem 2000;275:25858-25864.
15. Feitelson MA. Hepatitis B virus in hepatocarcinogenesis. J Cell Physiol 1999;181:188-202.
16. Feitelson MA, Zhu M, Duan LX, London WT. Hepatitis B X antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Oncogene 1993;8:1109-1117.
17. Wang XW, Forrester K, Yeh H, Feitelson MA, Gu J, Harris CC. Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with ERCC3. Proc Natl Acad Sci USA 1994;91:2230-2234.
18. Sirma H, Giannini C, Poussin K, Paterlini P, Kremsdorf D, Brechot C. Genetic and functional analysis of the effects of hepatitis B viral transactivator HBx on cell growth and apoptosis: Implications for viral replication and hepatocarcinogenesis. In: Fleig WE, editor. Normal and malignant liver cell growth: FALK Workshop. Lancaster, UK: Kluwer Academic Publishers; 1999. pp 171-186.
19. Chan YL, Olvera J, Paz V, Wool IG. The primary structure of rat ribosomal protein S15a. Biochem Biophys Res Commun 1994;200:1498-1504.
20. Schaap PJ, de Groot PW, Muller Y, van Griensven U, Visser J. Molecular cloning and sequence of the cytoplasmic ribosomal protein S15a gene from Agaricus bisporus. Exp Mycol 1995;19:160-162.
21. Westermann P, Gross B, Bielka H. Neighbourhoods of proteins S2-S3, S3-S3a, S15-S15a, and S5-S25 within the small subunit of rat liver ribosomes. Acta Biol Med Ger 1980;39:1147-1152.
22. Lavoie C, Tam R, Clark M, Lee H, Sonenberg N, Lasko P. Suppression of a temperature-sensitive cdc33 mutation of yeast by a multicopy plasmid expressing a Drosophila ribosomal protein. J Biol Chem 1994;269:14625-14630.
23. Reed SI. The selection of S. cerevisiae mutants defective in the start event of cell division. Genetics 1980;95:561-577.
24. Pringle JR, Hartwell LH. The Saccharomyces cerevisiae cell cycle. In: Strathern JN, Jones EW, Broach JR, editors. The molecular biology of the yeast Saccharomyces cerevisiae: Life cycle and inheritance. Cold Spring Harbor: Cold Spring Harbor Laboratory Press; 1981. pp 97-142.
25. Bonham-Smith PC, Moloney MM. Nucleotide and protein sequences of a cytoplasmic ribosomal protein S15a gene fromArabidopsis thaliana. Plant Physiol 1994;106:401-402.
26. Bonham-Smith PC, Oancia TL, Moloney MM. Cytoplasmic ribosomal protein S15a from Brassica napus: Molecular cloning and developmental expression in mitotically active tissues. Plant Mol Biol 1992;18:909-919.
27. Akiyama N, Matsuo Y, Sai H, Noda M, Kizaka-Kondoh S. Identification of a series of transforming growth factor beta-responsive genes by retrovirus-mediated gene trap screening. Mol Cell Biol 2000;9:3266-3273.
28. Lian Z, Pan J, Liu J, et al. The translation initiation factor, SUI1, may be a target of hepatitis B x antigen in hepatocarcinogenesis. Oncogene 1999;18:1677-1687..
29. Benson DA, Boguski MS, Lopman DJ, Ostell J. GenBank. Nucl Acids Res 1997;25:1-6.
30. Feitelson MA, Millman I, Duncan GD, Blumberg BS. Presence of antibodies to the polymerase gene product(s) of hepatitis B and woodchuck hepatitis virus in natural and experimental infections. J Med Virol 1988;24:121-136.
31. Feitelson MA, Clayton MM. X antigen polypeptides in the sera of hepatitis B virus infected patients. Virology 1990;177:367-371.
32. Feitelson MA, Clayton MM, Blumberg BS. X antigen/antibody markers in hepadnavirus infection: Presence and significance of hepadnavirus X gene product(s) in serum X antigen/antibody markers in hepadnavirus infection: Presence and significance of hepadnavirus X gene product(s) in serum Gastroenterology 1990;98:1071-1078.
33. Hohne M, Schaefer S, Seifer M, Feitelson MA, Paul D, Gerlich WG. Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA. EMBO J 1990;9:1137-1145.
34. Lian Z, Liu J, Pan J, et al. A cellular gene up-regulated by hepatitis B virus encoded X antigen promotes hepatocellular growth and survival. Hepatology 2001;34:146-157.
35. Tufan NLS, Lian Z, Liu J, et al. Hepatitis B x antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survival. Neoplasia 2002;4:355-368.
36. Brenner C, Nakayama N, Goebl M, Tanaka K, Tohe A, Matsumoto K. CDC33 encodes mRNA cap-binding protein eIF-4E of Saccharomyces cerevisiae. Mol Cell Biol 1988;8:3556-3559.
37. Linder P, Prat A. Baker's yeast, the new work horse in protein synthesis studies: Analyzing eukaryotic translation initiation. Bioassays 1990;12:519-526.
38. Lee DK, Park SH, Yi Y, et al. The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: Potential mechanism of hepatitis B virus-induced liver fibrosis. Genes Dev 2001;15:455-466.
39. Yoo YD, Ueda H, Park K, et al. Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis. J Clin Invest 1996;97:388-395.
40. Kim CM, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991;351:317-320.
41. Ueda H, Ullrich SJ, Gangemi JD, et al. Functional inactivation but not structural mutation of p53 causes liver cancer. Nat Genet 1995;9:41-47.
42. Sugano Y, Matsuzaki K, Tahashi Y, et al. Distortion of autocrine transforming growth factor beta signal accelerates malignant potential by enhancing cell growth as well as PAI-1 and VEGF production in human hepatocellular carcinoma cells. Oncogene 2003;22:2309-2321.
43. Teicher BA. Malignant cells, directors of the malignant process: Role of transforming growth factor-beta. Cancer Metastasis Rev 2001;20:133-143.
44. Huang J, Kwong J, Sun ECY, Liang TJ. Proteasome complex as a potential cellular target of hepatitis B virus X protein. J Virol 1996;70:5582-5591.
45. Hu Z, Zhang Z, Doo E, Coux O, Goldberg AL, Liang TJ. Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex. J Virol 1999;73:7231-7240.
46. Zhang Z, Torii N, Furusaka A, Malayaman N, Hu Z, Liang TJ. Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex. J Biol Chem 2000;275:15157-15165.
47. Lian Z, Liu J, Li L, et al. Up-regulated expression of a unique gene by hepatitis B x antigen promotes hepatocellular growth and tumorigenesis. Neoplasia 2003;5:229-244.