Identification of a series of transforming growth factor β-responsive genes by retrovirus-mediated gene trap screening

Molecular and Cellular Biology

Volumn 20, Issue 9, 2000, Pages 3266-3273

  Akiyama, Nobutake ^a   Matsuo, Yoshiyuki ^a   Sai, Heitetsu ^a   Noda, Makoto ^a   Kizaka Kondoh, Shinae ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; LIPOCORTIN 2; PAXILLIN; RIBOSOME PROTEIN; THYROID HORMONE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC SCREENING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RETROVIRUS; SEQUENCE ANALYSIS;

BETA-GALACTOSIDASE; BLOTTING, NORTHERN; DNA, COMPLEMENTARY; GALACTOSIDES; GENES, REPORTER; GENETIC TECHNIQUES; HUMANS; INDOLES; RETROVIRIDAE; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; UP-REGULATION;

RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0034004662     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.9.3266-3273.2000     Document Type: Article

References (53)

1. Akiyama, N., D. Alexander, Y. Aoki, and M. Noda. 1996. Characterization of mutations induced by 300 and 320 nm UV radiation in a rat fibroblast cell line. Mutat. Res. 372:119-131.
2. Andreu, T., T. Beckers, E. Thoenes, P. Hilgard, and H. von Melchner. 1998. Gene trapping identifies inhibitors of oncogenic transformation. J. Biol. Chem. 273:13848-13854.
3. Benditt, J. O., C. Mayer, H. Fasold, F. C. Barnard, and N. Riedel. 1989. Interaction of a nuclear location signal with isolated nuclear envelopes and identification of signal-binding proteins by photoaffinity labeling. Proc. Natl. Acad. Sci. USA 86:9327-9331.
4. Bonham-Smith, P. C., T. L. Oancia, and M. M. Moloney. 1992. Cytoplasmic ribosomal protein S15a from Brassica napus: molecular cloning and developmental expression in mitotically active tissues. Plant Mol. Biol. 18:909-919.
5. Bortolin, M. L., and T. Kiss. 1998. Human U19 intron-encoded snoRNA is processed from a long primary transcript thai possesses little potential for protein coding. RNA 4:445-454.
6. Cole, S. P., M. J. Pinkoski, G. Bhardwaj, and R. G. Deeley. 1992. Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line. Br. J. Cancer 65:498-502.
7. Datto, M. B., Y. Li, J. F. Panus, D. J. Howe, Y. Xiong, and X. F. Wang, 1995. Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA 92:5545-5549.
8. Dejgaard, K., H. Letters, H. H. Rasmussen, P. Madsen, T. A. Kruse, B. Gesser, H. Nielsen, and J. E. Celis. 1994. Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing. J. Mol. Biol. 236: 33-48.
9. Diatchenko, L., Y.-F. C. Lau, A. P. Campbell, A. Chenchik, F. Moqadam, B. Huang, S. Lukyanov, K. Lukyanov, N. Gurskaya, E. D. Sverdlov, and P. D. Siebert. 1996. Suppression subtractive hybridization: a method for generating differentially regulated or tissue specific cDNA probes and libraries. Proc. Natl. Acad. Sci. USA 93:6025-6030.
10. Dimri, G. P., X. Lee, G. M. Basile, M. Acosta, G. Scott, C. Roskelley, E. E. Medrano, M. Linskens, I. Rubel, O. Pereira-Smith, M. Peacocke, and J. Campisi. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92:9363-9367.
11. Forrester, L. M., A. Nagy, M. Sam, A. Watt, L. Stevenson, A. Bernstein, A. L. Joyner, and W. Wurst. 1996. An induction gene trap screen in embryonic stem cells: identification of genes that respond to retinoic acid in vitro. Proc. Natl. Acad. Sci. USA 93:1677-1682.
12. Friedrich, G., and P. Soriano. 1991. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5:1513-1523.
13. Fredrich, G., and P. Soriano. 1993. Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells. Methods Enzymol. 225:681-701.
14. Giancotti, F. G., and E. Ruoslahti. 1990. Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell 60:849-859.
15. Giard, D. J., S. A. Aaronson, G. J. Todaro, P. Arnstein, J. H. Kersey, H. Dosik, and W. P. Parks. 1973. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J. Natl. Cancer Inst. 51:1417-1423.
16. Gossler, A., and J. Zachgo. 1993. Gene and enhancer trap screens in ES cell chimeras, p. 181-277. In A. L. Joyner (ed.), Gene targeting: a practical approach. Oxford University Press, New York, N.Y.
17. Hahn, S. A., M. Schutte, A. T. Hoque, C. A. Moskaluk, L. T. de Costa, E. Rosenblum, C. L. Weinstein, A. Fischer, C. J. Xeo, R. H. Hruban, and S. E. Kern. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353.
18. INK4B is a potential effecter of TGF-β-induced cell cycle arrest. Nature 371:257-261.
19. Heino, J., R. A. Ignotz, M. E. Hemler, C. Crouse, and J. Massague. 1989. Regulation of cell adhesion receptors by transforming growth factor-β. Concomitant regulation of integrins that share a common beta 1 subunit. J. Biol. Chem. 264:380-388.
20. Heiss, N. S., G. Gloeckner, D. Bächner, P. Kioschis, S. M. Klauck, B. Hinzmann, A. Rosenthal, G. E. Herman, and A. Pouska. 1997. Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript. Genomics 43:329-338.
21. Heldin, C. H., K. Miyazono, and P. ten Dijke. 1997. TGF-β signaling from cell membrane to nucleus through SMAD proteins. Nature 390:465-471.
22. Huang, K. S., B. P. Wallner, R. J. Mattaliano, R. Tizard, C. Burne, A. Frey, C. Hession, P. McGray, L. K. Sinclair, and E. P. Chow. 1986. Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase. Cell 46:191-199.
23. Hubank, M., and S. G. Schatz. 1994. Identifying differences in mRNA expression by representational difference analysis of cDNA. Nucleic Acids Res. 22:5640-5648.
24. Kamakura, T., K. Kobayashi, T. Tanaka, I. Yamaguchi, and E. Toyoshige. 1987. Cloning and expression of a new structural gene for blasticidin S deaminase, a nucleoside aminohydrolase. Agric. Biol. Chem. 51:3165-3168.
25. Kato, H., T. Fukuda, C. Parkinson, P. McPhie, and S. Y. Cheng. 1989. Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase. Proc. Natl. Acad. Sci. USA 86:7861-7865.
26. Kerr, W. G., M. Heller, and L. A. Herzenberg. 1996. Analysis of lipopolysaccharide-response genes in B-lineage cells demonstrates that they can have differentiation stage-restricted expression and contain SH2 domains. Proc. Natl. Acad. Sci. USA 93:3947-3952.
27. Kuo, C. H., and W. W. Wells. 1978. β-Galactosidase from rat mammary gland. Its purification, properties, and role in the biosynthesis of 6β-O-D-galactopyranosyl myo-inositol. J. Biol. Chem. 253:3550-3556.
28. LaKatos, P., and P. H. Stern. 1992. Effects of cyclosporins and transforming growth factor beta 1 on thyroid hormone action in cultured fetal rat limb bones. Calcif. Tissue Int. 50:123-128.
29. Lee, N. H., K. G. Weinstock, E. F. Kirkness, J. A. Earle-Hughes, R. A. Fuldner, S. Marmaros, A. Glodek, J. D. Gocayne, M. D. Adams, A. R. Kerlavage, C. M. Fraser, and J. C. Venter. 1995. Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Proc. Natl. Acad. Sci. USA 92:8303-8307.
30. Liang, P., and A. B. Pardee. 1992. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971.
31. Libermann, T. A., H. R. Nusbaum, N. Razon, R. Kris, I. Lax, H. Soreq, N. Whittle, M. D. Waterfield, A. Ullrick, and J. Schlessinger. 1985. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumors of glial origin. Nature 313:144-147.
32. Markowitz, S. D., and A. B. Roberts. 1996. Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine Growth Factor Rev. 7:93-102.
33. Markowitz, D., S. Goff, and A. Bank. 1988. Construction and use of a safe and efficient amphotropic packaging call line. Virology 167:400-406.
34. Massague, J. 1998. TGF-β signal transduction. Annu. Rev. Biochem. 67: 753-791.
35. 2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing. J. Biol. Chem. 261:13807-13812.
36. Parry, H. D., and L. Alphey. 1987. The utilization of cloned DNAs to study gene organization and expression, p. 177-178. In D. M. Glover and B. D. Hames (ed.), DNA cloning 1, core techniques, 2nd ed. IRL Press, Oxford, United Kingdom.
37. Reynisdottir, I., K. Polyak, A. Iavarone, and J. Massague. 1995. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev. 9:1831-1845.
38. Roberts, A. B., M. A. Anzano, L. M. Wakefield, N. S. Roche, F. D. Stern, and M. B. Sporn. 1985. Type β transforming growth factor: a bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. USA 82:119-123.
39. Russ, A. P., C. Friedel, K. Ballas, U. Kalina, D. Zahn, K. Strebhardt, and H. von Melchner. 1996. Identification of genes induced by factor deprivation in hematopoietic cells undergoing apoptosis using gene-trap mutagenesis and site-specific recombination. Proc. Natl. Acad. Sci. USA 93:15279-15284.
40. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1987. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
41. Sanes, J. R., J. L. Rubenstein, and J. F. Nicolas. 1986. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 5:3133-3142.
42. Schena, M., K. Shalon, R. W. Davis, and P. O. Brown. 1995. Quantitative monitoring of gene expression patterns with a complementary DNA micro-array. Science 270:467-470.
43. Scheridin, U., K. Rhodes, and M. Breindl. 1990. Transcriptionally active genome regions are preferred targets for retrovirus integration. J. Virol. 64:907-912.
44. Simon, H. U., G. B. Mills, M. Kozlowski, D. Hogg, D. Branch, Y. Ishimi, and K. A. Siminovitch. 1994. Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-1-related gene product involved in the induction of cell proliferation. Biochem. J. 297:389-397.
45. Sumitani, S., S. Kasayama, and B. Sato. 1994. Tyroid hormone inhibits androgen-enhanced DNA synthesis in Shionogi carcinoma 115 cells without affecting autocrine growth factor mRNA expression. J. Steroid Biochem. Mol. Biol. 50:5-11.
46. Takeshita, A., G. R. Cardona, N. Koibuchi, C. S. Suen, and W. W. Chin. 1997. TRAM-1 a novel 160 kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1. J. Biol. Chem. 272:27629-27634.
47. Thompson, K. L., R. Assoian, M. R. Rosner, and C. J. Marshall. 1988. Transforming growth factor-β increases transcription of the genes encoding the epidermal growth factor receptor and fibronectin in normal rat kidney fibroblasts. J. Biol. Chem. 263:19519-19524.
48. Tong, X., and P. M. Howley. 1997. The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 94:4412-4417.
49. Ulloa, L., J. Doody, and J. Massague. 1999. Inhibition of transforming growth factor-β/SMAD signalling by interferon-γ/STAT pathway. Nature 397:710-713.
50. Vasmatzis, G., M. Essand, U. Brinkmann, B. Lee, and I. Pastan. 1998. Discovery of three genes specifically expressed in human prostate by expressed sequence tag database analysis. Proc. Natl. Acad. Sei. USA 95:300-304.
51. Velculescu, V. E., L. Zhang, B. Vogelstein, and K. W. Kizler. 1995. Serial analysis of gene expression. Science 270:484-487.
52. Zhang, Y., and R. Derynck. 1999. Regulation of Smad signaling by protein associations and signaling crosstalk. Trends Cell Biol. 9:274-279.
53. Zhang, Y., X.-H. Feng, and R. Derynck. 1998. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription. Nature 394:909-913.