Identification of purine inhibitors of phosphodiesterase 7 (PDE7)

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 11, 2004, Pages 2955-2958

  Pitts, William J ^a   Vaccaro, Wayne ^a   Huynh, Tram ^a   Leftheris, Katerina ^a   Roberge, Jacques Y ^a   Barbosa, Joseph ^a   Guo, Junqing ^a   Brown, Baerbel ^a   Watson, Andrew ^a   Donaldson, Karen ^a   Starling, Gary C ^a   Kiener, Peter A ^a   Poss, Michael A ^a   Dodd, John H ^a   Barrish, Joel C ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Inhibitor; PDE7; Phosphodiesterase 7

Indexed keywords

PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE VII; PURINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; PROTEIN FAMILY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; BINDING SITES; CELL LINE; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

EID: 2342516888     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.03.021     Document Type: Article

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