Synthesis and structure-activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 8, 2001, Pages 1081-1083

  Barnes, Matthew J ^a   Cooper, Nicola ^a   Davenport, Richard J ^a   Dyke, Hazel J ^a   Galleway, Fiona P ^a   Galvin, Frances C A ^a   Gowers, Lewis ^a   Haughan, Alan F ^a   Lowe, Christopher ^a   Meissner, Johannes W G ^a   Montana, John G ^a   Morgan, Trevor ^a   Picken, C Louise ^a   Watson, Robert J ^a  

^a UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE DERIVATIVE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE VII; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ENZYME INHIBITORS; GUANINE; INHIBITORY CONCENTRATION 50; ISOENZYMES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035938422     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00125-1     Document Type: Article

References (18)