Potential role of phosphodiesterase 7 in human T cell function: Comparative effects of two phosphodiesterase inhibitors

Clinical and Experimental Immunology

Volumn 128, Issue 3, 2002, Pages 460-466

  Nakata, A ^a   Ogawa, K ^a   Sasaki, T ^a   Koyama, N ^a   Wada, K ^a   Kotera, J ^a   Kikkawa, H ^a   Omori, K ^a   Kaminuma, O ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Cyclic AMP; Cytokine; Phosphodiesterase; T cell

Indexed keywords

2 [4 [6,7 DIETHOXY 2,3 BIS(HYDROXYMETHYL) 1 NAPHTHYL] 2 PYRIDYL] 4 (3 PYRIDYL) 1(2H) PHTHALAZINONE; ADENOSINE PHOSPHATE; CD3 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; ISOENZYME; MESSENGER RNA; MONOCLONAL ANTIBODY; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV INHIBITOR; PICLAMILAST; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATOPHAGOIDES FARINAE; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; HYPERSENSITIVITY; IC 50; IMMUNOMODULATION; MALE; MONONUCLEAR CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; BENZAMIDES; CELL DIVISION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTEINE ENDOPEPTIDASES; GENE EXPRESSION; GLYCOPROTEINS; HUMANS; INTERLEUKIN-2; INTERLEUKIN-4; INTERLEUKIN-5; ISOENZYMES; LEUKOCYTES, MONONUCLEAR; PHOSPHODIESTERASE INHIBITORS; PHTHALAZINES; PYRIDINES; RECEPTORS, INTERLEUKIN-2; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0036277784     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2002.01856.x     Document Type: Article

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