-
2
-
-
0024459013
-
Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease
-
Yoshizaki K., Matsuda T., Nishimoto N., Kuritani T., Taeho L., Aozasa K., Nakahata T., Kawai H., Tagoh H., Komori T., Kishimoto S., Hirano T., Kishimoto T. Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood. 74:1989;1360-1367.
-
(1989)
Blood
, vol.74
, pp. 1360-1367
-
-
Yoshizaki, K.1
Matsuda, T.2
Nishimoto, N.3
Kuritani, T.4
Taeho, L.5
Aozasa, K.6
Nakahata, T.7
Kawai, H.8
Tagoh, H.9
Komori, T.10
Kishimoto, S.11
Hirano, T.12
Kishimoto, T.13
-
3
-
-
0025183151
-
Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice
-
Brant S.J., Bodine D.M., Dunbar C.E., Nienhuis A.W. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest. 86:1990;592-599.
-
(1990)
J Clin Invest
, vol.86
, pp. 592-599
-
-
Brant, S.J.1
Bodine, D.M.2
Dunbar, C.E.3
Nienhuis, A.W.4
-
4
-
-
0024269961
-
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis
-
Hirano T., Matsuda T., Turner M., Miyasaka N., Buchan G., Tang B., Sato K., Shimizu M., Murashima A., Tsunasawa S., Sakiyama F., Kishimoto T. Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol. 18:1988;1797-1801.
-
(1988)
Eur J Immunol
, vol.18
, pp. 1797-1801
-
-
Hirano, T.1
Matsuda, T.2
Turner, M.3
Miyasaka, N.4
Buchan, G.5
Tang, B.6
Sato, K.7
Shimizu, M.8
Murashima, A.9
Tsunasawa, S.10
Sakiyama, F.11
Kishimoto, T.12
-
5
-
-
0023942493
-
Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritis
-
Houssiau F.A., Devogelaer J.P., Damme J.V., de Deuxchaicnes C.N., Snick J.V. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritis. Arthritis Rheum. 31:1988;784-788.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 784-788
-
-
Houssiau, F.A.1
Devogelaer, J.P.2
Damme, J.V.3
De Deuxchaicnes, C.N.4
Snick, J.V.5
-
6
-
-
0024805715
-
Involvement of IL-6 in mesangial proliferative glomerulonephritis
-
Horii Y., Muraguchi A., Iwano M., Matsuda T., Hirayama T., Yamada H., Fujii Y., Dohi K., Ishikawa H., Ohmoto Y., Yoshizaki K., Hirano T., Kishimoto T. Involvement of IL-6 in mesangial proliferative glomerulonephritis. J Immunol. 143:1989;3949-3955.
-
(1989)
J Immunol
, vol.143
, pp. 3949-3955
-
-
Horii, Y.1
Muraguchi, A.2
Iwano, M.3
Matsuda, T.4
Hirayama, T.5
Yamada, H.6
Fujii, Y.7
Dohi, K.8
Ishikawa, H.9
Ohmoto, Y.10
Yoshizaki, K.11
Hirano, T.12
Kishimoto, T.13
-
7
-
-
0025103894
-
Interleukin 6 is an autocrine growth factor for mesangial cell
-
Ruef C., Budde K., Lacy J., Northemann W., Baumann M., Sterzel R.B., Coleman D.L. Interleukin 6 is an autocrine growth factor for mesangial cell. Kidney Int. 38:1990;249-257.
-
(1990)
Kidney Int
, vol.38
, pp. 249-257
-
-
Ruef, C.1
Budde, K.2
Lacy, J.3
Northemann, W.4
Baumann, M.5
Sterzel, R.B.6
Coleman, D.L.7
-
8
-
-
0023237098
-
Identification of the human 26-kD protein, interferon b2, as a cell hybridoma/plasmacytoma growth factor induced by interleukin-1 and tumor necrosis factor
-
Van Damme J., Opdenakker G., Simpson R.J., Rubira M.R., Cayphas S., Vink A., Billiau A., Van Snick J. Identification of the human 26-kD protein, interferon b2, as a cell hybridoma/plasmacytoma growth factor induced by interleukin-1 and tumor necrosis factor. J Exp Med. 165:1987;914-919.
-
(1987)
J Exp Med
, vol.165
, pp. 914-919
-
-
Van Damme, J.1
Opdenakker, G.2
Simpson, R.J.3
Rubira, M.R.4
Cayphas, S.5
Vink, A.6
Billiau, A.7
Van Snick, J.8
-
9
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano M., Hirano T., Matsuda T., Taga T., Horii Y., Iwato K., Asaoku H., Tang B., Tanabe O., Tanaka H., Kuramoto A., Kishimoto T. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature. 332:1988;83-85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
Taga, T.4
Horii, Y.5
Iwato, K.6
Asaoku, H.7
Tang, B.8
Tanabe, O.9
Tanaka, H.10
Kuramoto, A.11
Kishimoto, T.12
-
10
-
-
0024451525
-
Increased plasma levels of interleukin-6 in sepsis
-
Hack C.E., de Groot E.R., Felt-Bersma R.J., Nuijens J.H., Strack Van Schijndel R.J., Eerenberg-Belmer A.J., Thijs L.G., Aarden L.A. Increased plasma levels of interleukin-6 in sepsis. Blood. 74:1989;1704-1710.
-
(1989)
Blood
, vol.74
, pp. 1704-1710
-
-
Hack, C.E.1
De Groot, E.R.2
Felt-Bersma, R.J.3
Nuijens, J.H.4
Strack Van Schijndel, R.J.5
Eerenberg-Belmer, A.J.6
Thijs, L.G.7
Aarden, L.A.8
-
11
-
-
0024529891
-
The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1 and fatal outcome
-
Waage A., Brandtzaeg P., Halstensen A., Kierulf P., Espevik T. The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1 and fatal outcome. J Exp Med. 169:1989;333-338.
-
(1989)
J Exp Med
, vol.169
, pp. 333-338
-
-
Waage, A.1
Brandtzaeg, P.2
Halstensen, A.3
Kierulf, P.4
Espevik, T.5
-
12
-
-
0025896935
-
Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice
-
Black K., Garrett I.R., Mundy G.R. Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice. Endocrinology. 128:1991;2657-2659.
-
(1991)
Endocrinology
, vol.128
, pp. 2657-2659
-
-
Black, K.1
Garrett, I.R.2
Mundy, G.R.3
-
13
-
-
0026689535
-
Evidence for the involvement of interleukin 6 in experimental cancer cachexia
-
Strassmann G., Fong M., Kenney J.S., Jacob C.O. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest. 89:1992;1681-1684.
-
(1992)
J Clin Invest
, vol.89
, pp. 1681-1684
-
-
Strassmann, G.1
Fong, M.2
Kenney, J.S.3
Jacob, C.O.4
-
14
-
-
0028013066
-
Alleviation of systemic manifestations of Castleman's disease by monoclonal anti-interleukin-6 antibody
-
Beck J.T., Hsu S.M., Wijdense J., Bataille R., Klein B., Vesole D., Hayden K., Jagannath S., Barlogie B. Alleviation of systemic manifestations of Castleman's disease by monoclonal anti-interleukin-6 antibody. N Engl J Med. 330:1994;602-605.
-
(1994)
N Engl J Med
, vol.330
, pp. 602-605
-
-
Beck, J.T.1
Hsu, S.M.2
Wijdense, J.3
Bataille, R.4
Klein, B.5
Vesole, D.6
Hayden, K.7
Jagannath, S.8
Barlogie, B.9
-
15
-
-
0027402917
-
Treatment of severe rheumatoid arthritis by anti-interleukin-6 monoclonal antibody
-
Wendling D., Racadot E., Wijenes J. Treatment of severe rheumatoid arthritis by anti-interleukin-6 monoclonal antibody. J Rheumatol. 20:1993;259-262.
-
(1993)
J Rheumatol
, vol.20
, pp. 259-262
-
-
Wendling, D.1
Racadot, E.2
Wijenes, J.3
-
16
-
-
0033959608
-
Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy
-
Nishimoto N., Sasai M., Shima Y., Nakagawa M., Matsumoto T., Shirai T., Kishimoto T., Yoshizaki K. Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. Blood. 95:2000;56-61.
-
(2000)
Blood
, vol.95
, pp. 56-61
-
-
Nishimoto, N.1
Sasai, M.2
Shima, Y.3
Nakagawa, M.4
Matsumoto, T.5
Shirai, T.6
Kishimoto, T.7
Yoshizaki, K.8
-
17
-
-
0345317621
-
IgG1 plasmacytosis in interleukin 6 transgenic mice
-
Suematsu S., Matsuda T., Aozasa K., Akira S., Nakano N., Ohno S., Miyazaki J., Yamamura K., Hirano T., Kishimoto T. IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci USA. 86:1989;7547-7551.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7547-7551
-
-
Suematsu, S.1
Matsuda, T.2
Aozasa, K.3
Akira, S.4
Nakano, N.5
Ohno, S.6
Miyazaki, J.7
Yamamura, K.8
Hirano, T.9
Kishimoto, T.10
-
18
-
-
0031080815
-
Interleukin-6 overexpression cannot generate serious disorders in severe combined immunodeficiency mice
-
Katsume A., Miyai T., Suzuki H., Moriguchi Y., Kawara H., Tatsumi T., Suematsu S., Kishimoto T., Ohugi Y. Interleukin-6 overexpression cannot generate serious disorders in severe combined immunodeficiency mice. Clin Immuno Immunopathol. 82:1997;117-124.
-
(1997)
Clin Immuno Immunopathol
, vol.82
, pp. 117-124
-
-
Katsume, A.1
Miyai, T.2
Suzuki, H.3
Moriguchi, Y.4
Kawara, H.5
Tatsumi, T.6
Suematsu, S.7
Kishimoto, T.8
Ohugi, Y.9
-
19
-
-
0028966015
-
Muscle undergoes atrophy in association with increase of lysosomal cathepsin activity in interleukin-6 transgenic mouse
-
Tsujinaka T., Ebisui C., Fujita J., Kishibuchi M., Morimoto T., Ogawa A., Katsume A., Ohsugi Y., Kominami E., Monden M. Muscle undergoes atrophy in association with increase of lysosomal cathepsin activity in interleukin-6 transgenic mouse. Biochem Biophys Res Commun. 207:1995;168-174.
-
(1995)
Biochem Biophys Res Commun
, vol.207
, pp. 168-174
-
-
Tsujinaka, T.1
Ebisui, C.2
Fujita, J.3
Kishibuchi, M.4
Morimoto, T.5
Ogawa, A.6
Katsume, A.7
Ohsugi, Y.8
Kominami, E.9
Monden, M.10
-
20
-
-
0027136189
-
Soluble interleukin-6 receptor triggers osteoclast formation by interleukin-6
-
Tamura T., Udagawa N., Takahashi N., Miyaura C., Tanaka S., Yamada Y., Koishihara Y., Ohsugi Y., Kumaki K., Taga T., Kishimoto T., Suda T. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin-6. Proc Natl Acad Sci USA. 90:1993;11924-11928.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11924-11928
-
-
Tamura, T.1
Udagawa, N.2
Takahashi, N.3
Miyaura, C.4
Tanaka, S.5
Yamada, Y.6
Koishihara, Y.7
Ohsugi, Y.8
Kumaki, K.9
Taga, T.10
Kishimoto, T.11
Suda, T.12
-
21
-
-
0023922061
-
Establishment of an interleukin 6 (IL6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL6 monoclonal antibodies
-
Matsuda T., Hirano T., Kishimoto T. Establishment of an interleukin 6 (IL6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL6 monoclonal antibodies. Eur J Immunol. 18:1988;951-956.
-
(1988)
Eur J Immunol
, vol.18
, pp. 951-956
-
-
Matsuda, T.1
Hirano, T.2
Kishimoto, T.3
-
22
-
-
13344261948
-
Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice
-
Tsujinaka T., Fujita J., Ebisui C., Yano M., Kominami E., Suzuki K., Tanaka K., Katsume A., Ohsugi Y., Shiozaki H., Monden M. Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice. J Clin Invest. 97:1996;244-249.
-
(1996)
J Clin Invest
, vol.97
, pp. 244-249
-
-
Tsujinaka, T.1
Fujita, J.2
Ebisui, C.3
Yano, M.4
Kominami, E.5
Suzuki, K.6
Tanaka, K.7
Katsume, A.8
Ohsugi, Y.9
Shiozaki, H.10
Monden, M.11
-
23
-
-
0028328436
-
Impaired immune and acute-phase responses in interleukin-6-deficient mice
-
Kopf M., Baumann H., Freer G., Freudenberg M., Lamers M., Kishimoto T., Zinkernagel R., Bluethmann H., Kohler G. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature. 368:1994;339-342.
-
(1994)
Nature
, vol.368
, pp. 339-342
-
-
Kopf, M.1
Baumann, H.2
Freer, G.3
Freudenberg, M.4
Lamers, M.5
Kishimoto, T.6
Zinkernagel, R.7
Bluethmann, H.8
Kohler, G.9
-
24
-
-
0023851809
-
The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells
-
Muraguchi A., Hirano T., Tang B., Matsuda T., Horii Y., Nakajima K., Kishimoto T. The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med. 167:1988;332-344.
-
(1988)
J Exp Med
, vol.167
, pp. 332-344
-
-
Muraguchi, A.1
Hirano, T.2
Tang, B.3
Matsuda, T.4
Horii, Y.5
Nakajima, K.6
Kishimoto, T.7
-
25
-
-
0023913455
-
Stimulation of murine hemopoietic colony formation by human IL-6
-
Wong G.G., Witek-Giannotti J.S., Temple P.A., Kriz R., Ferenz C., Hewick R.M., Clark S.C., Ikebuchi K., Ogawa M. Stimulation of murine hemopoietic colony formation by human IL-6. J Immunol. 140:1988;3040-3044.
-
(1988)
J Immunol
, vol.140
, pp. 3040-3044
-
-
Wong, G.G.1
Witek-Giannotti, J.S.2
Temple, P.A.3
Kriz, R.4
Ferenz, C.5
Hewick, R.M.6
Clark, S.C.7
Ikebuchi, K.8
Ogawa, M.9
-
26
-
-
0024498048
-
In vivo hematologic effects of recombinant interleukin-6 on hematopoiesis and circulating numbers of RBCs and WBCs
-
Ulich T.R., del Castillo J., Guo K. In vivo hematologic effects of recombinant interleukin-6 on hematopoiesis and circulating numbers of RBCs and WBCs. Blood. 73:1989;108-110.
-
(1989)
Blood
, vol.73
, pp. 108-110
-
-
Ulich, T.R.1
Del Castillo, J.2
Guo, K.3
-
27
-
-
0024502002
-
Human interleukin-6 supports granulocytic differentiation of hematopoietic progenitor cells and acts synergistically with GM-CSF
-
Caracciolo D., Clark S.C., Rovera G. Human interleukin-6 supports granulocytic differentiation of hematopoietic progenitor cells and acts synergistically with GM-CSF. Blood. 73:1989;666-670.
-
(1989)
Blood
, vol.73
, pp. 666-670
-
-
Caracciolo, D.1
Clark, S.C.2
Rovera, G.3
-
28
-
-
0025293049
-
Interleukin 6 perfusion stimulates reconstitution of the immune, and hematopoietic systems after 5-fluorouracil treatment
-
Takatsuki F., Okano A., Suzuki C., Miyasaka Y., Hirano T., Kishimoto T., Ejima D., Akiyama Y. Interleukin 6 perfusion stimulates reconstitution of the immune, and hematopoietic systems after 5-fluorouracil treatment. Cancer Res. 50:1990;2885-2890.
-
(1990)
Cancer Res
, vol.50
, pp. 2885-2890
-
-
Takatsuki, F.1
Okano, A.2
Suzuki, C.3
Miyasaka, Y.4
Hirano, T.5
Kishimoto, T.6
Ejima, D.7
Akiyama, Y.8
-
29
-
-
0028824032
-
Bone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice
-
Kitamura H., Kawata H., Takahashi F., Higuchi Y., Furuichi T., Ohkawa H. Bone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice. Am J Pathol. 147:1995;1682-1692.
-
(1995)
Am J Pathol
, vol.147
, pp. 1682-1692
-
-
Kitamura, H.1
Kawata, H.2
Takahashi, F.3
Higuchi, Y.4
Furuichi, T.5
Ohkawa, H.6
-
30
-
-
0028176283
-
CMpl ligand is a humoral regulator of megakaryocytopoiesis
-
Wendling F., Maraskovsky E., Debili N., Florindo C., Teepe M., Titeux M., Methia N., Breton-Gorius J., Cosman D., Vainchenker W. cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature. 369:1994;571-574.
-
(1994)
Nature
, vol.369
, pp. 571-574
-
-
Wendling, F.1
Maraskovsky, E.2
Debili, N.3
Florindo, C.4
Teepe, M.5
Titeux, M.6
Methia, N.7
Breton-Gorius, J.8
Cosman, D.9
Vainchenker, W.10
-
31
-
-
0028332474
-
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
-
Kaushansky K., Lok S., Holly R.D., Broudy V.C., Lin N., Bailey M.C., Forsrom J.W., Buddle M.M., Oort P.J., Hagen F.S., Roth G.J., Papayannopoulou T., Foster D.C. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature. 369:1994;568-571.
-
(1994)
Nature
, vol.369
, pp. 568-571
-
-
Kaushansky, K.1
Lok, S.2
Holly, R.D.3
Broudy, V.C.4
Lin, N.5
Bailey, M.C.6
Forsrom, J.W.7
Buddle, M.M.8
Oort, P.J.9
Hagen, F.S.10
Roth, G.J.11
Papayannopoulou, T.12
Foster, D.C.13
-
32
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de Sauvage F.J., Hass P.E., Spencer S.D., Malloy B.E., Gurney A.L., Spencer S.A., Darbonne W.C., Henzel W.J., Wong S.C., Kuang W., Oles K.J., Hultgren B., Solberg L.A., Goeddel D.V., Eaton D.L. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature. 369:1994;533-538.
-
(1994)
Nature
, vol.369
, pp. 533-538
-
-
De Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.10
Oles, K.J.11
Hultgren, B.12
Solberg, L.A.13
Goeddel, D.V.14
Eaton, D.L.15
-
33
-
-
0022723965
-
Purification and characterization of human granulocyte colony-stimulating factor (G-CSF)
-
Nomura H., Imazeki I., Oheda M., Kubota N., Tamura M., Ono M., Ueyama Y., Asano S. Purification and characterization of human granulocyte colony-stimulating factor (G-CSF). EMBO J. 5:1986;871-876.
-
(1986)
EMBO J
, vol.5
, pp. 871-876
-
-
Nomura, H.1
Imazeki, I.2
Oheda, M.3
Kubota, N.4
Tamura, M.5
Ono, M.6
Ueyama, Y.7
Asano, S.8
-
34
-
-
10544222015
-
Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways
-
Fujita J., Tsujinaka T., Yano M., Ebisui C., Saito H., Katsume A., Akamatsu K., Ohsugi Y., Shiozaki H., Monden M. Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways. Int J Cancer. 68:1996;637-643.
-
(1996)
Int J Cancer
, vol.68
, pp. 637-643
-
-
Fujita, J.1
Tsujinaka, T.2
Yano, M.3
Ebisui, C.4
Saito, H.5
Katsume, A.6
Akamatsu, K.7
Ohsugi, Y.8
Shiozaki, H.9
Monden, M.10
-
35
-
-
0026739591
-
Reversible inhibition of albumin production by rat hepatocytes maintained on a laminin-rich gel (Engelbreth-Holm-Swarm) in response to secretory products of Kupffer cells and cytokines
-
Kowalski-Saunders P.W., Winwood P.J., Arthur M.J., Wright R. Reversible inhibition of albumin production by rat hepatocytes maintained on a laminin-rich gel (Engelbreth-Holm-Swarm) in response to secretory products of Kupffer cells and cytokines. Hepatology. 16:1992;733-741.
-
(1992)
Hepatology
, vol.16
, pp. 733-741
-
-
Kowalski-Saunders, P.W.1
Winwood, P.J.2
Arthur, M.J.3
Wright, R.4
|