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Volumn 9, Issue 1, 2004, Pages 3-10

Alcoholic macrocytosis - Is there a role for acetaldehyde and adducts?

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL;

EID: 2342464852     PISSN: 13556215     EISSN: None     Source Type: Journal    
DOI: 10.1080/13556210410001674031     Document Type: Review
Times cited : (39)

References (85)
  • 1
    • 0023394599 scopus 로고
    • Haematologic complications of alcohol abuse
    • Lindenbaum J. Haematologic complications of alcohol abuse. Semin Liver Dis 1987;7:169-81.
    • (1987) Semin Liver Dis , vol.7 , pp. 169-181
    • Lindenbaum, J.1
  • 3
    • 0025338458 scopus 로고
    • Recognition and evaluation of red blood cell macrocytosis in the primary care setting
    • Wymer A, Becker DM. Recognition and evaluation of red blood cell macrocytosis in the primary care setting. J Gen Intern Med 1990;5:192-7.
    • (1990) J Gen Intern Med , vol.5 , pp. 192-197
    • Wymer, A.1    Becker, D.M.2
  • 5
    • 0025930911 scopus 로고
    • Macrocytosis as a consequence of alcohol abuse among patients in general practice
    • Seppä K, Laippala P, Saarni, M. Macrocytosis as a consequence of alcohol abuse among patients in general practice. Alcohol Clin Exp Res 1991;15:871-6.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 871-876
    • Seppä, K.1    Laippala, P.2    Saarni, M.3
  • 6
    • 2342659100 scopus 로고
    • Metabolic effects of alcohol on the blood and bone marrow
    • Lieber CS, editor. Baltimore: University Park Press
    • Lindenbaum J. Metabolic effects of alcohol on the blood and bone marrow. In: Lieber CS, editor. Metabolic aspects of alcoholism. Baltimore: University Park Press, 1977:215-47.
    • (1977) Metabolic Aspects of Alcoholism , pp. 215-247
    • Lindenbaum, J.1
  • 7
    • 0035171536 scopus 로고    scopus 로고
    • Red blood cell status in alcoholic and non-alcoholic liver disease
    • Maruyama S, Hirayama C, Yamamoto S, et al. Red blood cell status in alcoholic and non-alcoholic liver disease. J Lab Clin Med 2001;138:332-7.
    • (2001) J Lab Clin Med , vol.138 , pp. 332-337
    • Maruyama, S.1    Hirayama, C.2    Yamamoto, S.3
  • 8
    • 0016367265 scopus 로고
    • Macrocytosis of chronic alcoholism
    • Wu A, Chanarin I, Levi AJ. Macrocytosis of chronic alcoholism. Lancet. 1974;4:829-31.
    • (1974) Lancet. , vol.4 , pp. 829-831
    • Wu, A.1    Chanarin, I.2    Levi, A.J.3
  • 10
    • 0030476413 scopus 로고    scopus 로고
    • Laboratory markers of alcohol abuse
    • Sillanaukee, P. Laboratory markers of alcohol abuse. Alcohol Alcohol 1996;6:613-16.
    • (1996) Alcohol Alcohol , vol.6 , pp. 613-616
    • Sillanaukee, P.1
  • 11
    • 79958280369 scopus 로고    scopus 로고
    • Serum diagnosis of ALD and markers of ethanol intake
    • Sherman D, Preedy V, Watson R, editors. London: Taylor and Francis Academic Publishers
    • Niemelä O. Serum diagnosis of ALD and markers of ethanol intake. In: Ethanol and the liver: mechanisms and management. Sherman D, Preedy V, Watson R, editors. London: Taylor and Francis Academic Publishers, 2002;411-49.
    • (2002) Ethanol and the Liver: Mechanisms and Management , pp. 411-449
    • Niemelä, O.1
  • 12
    • 0023608068 scopus 로고
    • Alcohol-induced bone marrow damage. A bone marrow study in alcohol-dependent individuals
    • Michot F, Gut J. Alcohol-induced bone marrow damage. A bone marrow study in alcohol-dependent individuals. Acta Haematol 1978;78:252-7.
    • (1978) Acta Haematol , vol.78 , pp. 252-257
    • Michot, F.1    Gut, J.2
  • 13
    • 0019982642 scopus 로고
    • Suppression of haematopoietic-progenitor-cell proliferation by ethanol and acetaldehyde
    • Meagher RC, Sieber F, Spivak JL. Suppression of haematopoietic- progenitor-cell proliferation by ethanol and acetaldehyde. N Engl J Med 1982;30:845-9.
    • (1982) N Engl J Med , vol.30 , pp. 845-849
    • Meagher, R.C.1    Sieber, F.2    Spivak, J.L.3
  • 15
    • 0023755927 scopus 로고
    • Alcohol abuse increases the lipid structural order in human erythrocyte membranes. A steady-state and time-resolved anisotrophy study
    • Beauge F, Gallay J, Stibler H, Borg S. Alcohol abuse increases the lipid structural order in human erythrocyte membranes. A steady-state and time-resolved anisotrophy study. Biochem Pharmacol 1988;37:3823-8.
    • (1988) Biochem Pharmacol , vol.37 , pp. 3823-3828
    • Beauge, F.1    Gallay, J.2    Stibler, H.3    Borg, S.4
  • 16
    • 0022475826 scopus 로고
    • Acetaldehyde causes a prolongation of the doubling time and an increase in the modal volume of cells in culture
    • Wickramasinghe SN, Malik F. Acetaldehyde causes a prolongation of the doubling time and an increase in the modal volume of cells in culture. Alcohol Clin Exp Res 1986;10:350-4.
    • (1986) Alcohol Clin Exp Res , vol.10 , pp. 350-354
    • Wickramasinghe, S.N.1    Malik, F.2
  • 17
    • 0036129491 scopus 로고    scopus 로고
    • In vitro effects of ethanol, acetaldehyde and fatty acid ethyl esters on human erythrocytes
    • Tyulina OV, Prokopieva VD, Dodd RD, et al. In vitro effects of ethanol, acetaldehyde and fatty acid ethyl esters on human erythrocytes. Alcohol Alcohol 2002;37:179-86.
    • (2002) Alcohol Alcohol , vol.37 , pp. 179-186
    • Tyulina, O.V.1    Prokopieva, V.D.2    Dodd, R.D.3
  • 18
    • 0024424849 scopus 로고
    • Characterization of the increased binding of acetaldehyde to red blood cells in alcoholics
    • Hernández-Muños R, Baraona E, Blacksberg I, Lieber CS. Characterization of the increased binding of acetaldehyde to red blood cells in alcoholics. Alcohol Clin Exp Res 1989;13:654-9.
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 654-659
    • Hernández-Muños, R.1    Baraona, E.2    Blacksberg, I.3    Lieber, C.S.4
  • 19
    • 0025689018 scopus 로고
    • In vivo accelerated acetaldehyde metabolism using acetaldehyde dehydrogenase-loaded erythrocytes
    • Magnani M, Laguerre M, Rosa L, et al. In vivo accelerated acetaldehyde metabolism using acetaldehyde dehydrogenase-loaded erythrocytes. Alcohol Alcohol 1990;25:627-37.
    • (1990) Alcohol Alcohol , vol.25 , pp. 627-637
    • Magnani, M.1    Laguerre, M.2    Rosa, L.3
  • 20
    • 0031729547 scopus 로고    scopus 로고
    • Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: Effects of gender and hemoglobin concentration
    • Hazelett SE, Liebelt RA, Brown WJ, Androulakakis V, Jarjoura D, Truitt EB Jr. Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration. Alcohol Clin Exp Res 1998;22:1811-19.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 1811-1819
    • Hazelett, S.E.1    Liebelt, R.A.2    Brown, W.J.3    Androulakakis, V.4    Jarjoura, D.5    Truitt Jr., E.B.6
  • 21
    • 0033963854 scopus 로고    scopus 로고
    • Accumulation of hemoglobin-associated acetaldehyde with habitual alcohol drinking in the atypical ALDH2 genotype
    • Takeshita M, Morimoto K. Accumulation of hemoglobin-associated acetaldehyde with habitual alcohol drinking in the atypical ALDH2 genotype. Alcohol Clin Exp Res 2000;24:1-7.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1-7
    • Takeshita, M.1    Morimoto, K.2
  • 22
    • 0035379410 scopus 로고    scopus 로고
    • Acetaldehyde adducts in blood and bone marrow of patients with ethanol-induced erythrocyte abnormalities
    • Latvala J, Parkkila S, Melkko J, Niemelä O. Acetaldehyde adducts in blood and bone marrow of patients with ethanol-induced erythrocyte abnormalities. Mol Med 2001;7:401-5.
    • (2001) Mol Med , vol.7 , pp. 401-405
    • Latvala, J.1    Parkkila, S.2    Melkko, J.3    Niemelä, O.4
  • 23
    • 0034975104 scopus 로고    scopus 로고
    • The role of acetaldehyde in the actions of alcohol
    • Eriksson CJ. The role of acetaldehyde in the actions of alcohol. Alcohol Clin Exp Res 2001;25:S15-32.
    • (2001) Alcohol Clin Exp Res , vol.25
    • Eriksson, C.J.1
  • 24
    • 0024158490 scopus 로고
    • Rapid association of acetaldehyde with hemoglobin in human volunteers after low dose ethanol
    • Peterson CM, Jovanovic-Peterson L, Schmid-Formby F. Rapid association of acetaldehyde with hemoglobin in human volunteers after low dose ethanol. Alcohol 1988;5:371-4.
    • (1988) Alcohol , vol.5 , pp. 371-374
    • Peterson, C.M.1    Jovanovic-Peterson, L.2    Schmid-Formby, F.3
  • 25
    • 0017363085 scopus 로고
    • Reaction of acetaldehyde with human erythrocyte membrane proteins
    • Gaines KC, Salhany JM, Tuma DJ, Sorrell MF. Reaction of acetaldehyde with human erythrocyte membrane proteins. FEBS Letters, 1979;75:115-19.
    • (1979) FEBS Letters , vol.75 , pp. 115-119
    • Gaines, K.C.1    Salhany, J.M.2    Tuma, D.J.3    Sorrell, M.F.4
  • 26
    • 0026775371 scopus 로고
    • Hemoglobin-acetaldehyde adducts in human alcohol abusers
    • Niemelä O, Israel Y. Hemoglobin-acetaldehyde adducts in human alcohol abusers. Lab Invest 1992;67:246-52.
    • (1992) Lab Invest , vol.67 , pp. 246-252
    • Niemelä, O.1    Israel, Y.2
  • 27
    • 0028810725 scopus 로고
    • Medical disorders of alcoholism
    • Lieber CS. Medical disorders of alcoholism. N Engl J Med 1995;333:1058-65.
    • (1995) N Engl J Med , vol.333 , pp. 1058-1065
    • Lieber, C.S.1
  • 28
    • 0026460942 scopus 로고
    • Immune responses to acetaldehyde-protein adducts: Role in alcoholic liver disease
    • Tuma DJ, Klassen LW. Immune responses to acetaldehyde-protein adducts: role in alcoholic liver disease. Gastroenterology 1992;103:1969-73.
    • (1992) Gastroenterology , vol.103 , pp. 1969-1973
    • Tuma, D.J.1    Klassen, L.W.2
  • 29
    • 0033146334 scopus 로고    scopus 로고
    • Acetaldehyde-protein adducts in the liver as a result of ethanol-induced oxidative stress
    • Niemelä O. Acetaldehyde-protein adducts in the liver as a result of ethanol-induced oxidative stress. Front Biosci 1999;4:D506-13.
    • (1999) Front Biosci , vol.4
    • Niemelä, O.1
  • 31
    • 0010562619 scopus 로고
    • Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts
    • Israel Y, Hurwitz E, Niemelä O, Arnon R. Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts. Proc Natl Acad Sci USA 1986;83:7923-7.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7923-7927
    • Israel, Y.1    Hurwitz, E.2    Niemelä, O.3    Arnon, R.4
  • 32
    • 0023086901 scopus 로고
    • The functional implications of acetaldehyde binding to cell constituents
    • Sorrell MF, Tuma DJ. The functional implications of acetaldehyde binding to cell constituents. Ann NY Acad Sci, 1987;492:50-62.
    • (1987) Ann NY Acad Sci , vol.492 , pp. 50-62
    • Sorrell, M.F.1    Tuma, D.J.2
  • 33
    • 0026490942 scopus 로고
    • Modification of proteins and other biological molecules by acetaldehyde: Adduct structure and functional significance
    • Nicholls R, de Jersey J, Worrall S, Wilce P. Modification of proteins and other biological molecules by acetaldehyde: adduct structure and functional significance. Int J Biochem 1992;24:1899-906.
    • (1992) Int J Biochem , vol.24 , pp. 1899-1906
    • Nicholls, R.1    De Jersey, J.2    Worrall, S.3    Wilce, P.4
  • 35
    • 0022849376 scopus 로고
    • Reaction of acetaldehyde with hemoglobin
    • San George RC, Hoberman HD. Reaction of acetaldehyde with hemoglobin. J Biol Chem 1986;261:6811-21.
    • (1986) J Biol Chem , vol.261 , pp. 6811-6821
    • San George, R.C.1    Hoberman, H.D.2
  • 36
    • 0024493970 scopus 로고
    • Preferential covalent binding of acetaldehyde to the α-chain of purified rat liver tubulin
    • Jennett RB, Sorrell MF, Saffari-Fard A, Ockner JL, Tuma DJ. Preferential covalent binding of acetaldehyde to the α-chain of purified rat liver tubulin. Hepatology 1989;9:57-62.
    • (1989) Hepatology , vol.9 , pp. 57-62
    • Jennett, R.B.1    Sorrell, M.F.2    Saffari-Fard, A.3    Ockner, J.L.4    Tuma, D.J.5
  • 37
    • 0023573883 scopus 로고
    • Covalent binding of acetaldehyde to proteins: Participation of lysine residues
    • Tuma DJ, Newman MR, Donohue TM, Sorrell MF. Covalent binding of acetaldehyde to proteins: participation of lysine residues. Alcohol Clin Exp Res 1987;11:579-84.
    • (1987) Alcohol Clin Exp Res , vol.11 , pp. 579-584
    • Tuma, D.J.1    Newman, M.R.2    Donohue, T.M.3    Sorrell, M.F.4
  • 39
    • 0029079316 scopus 로고
    • A structural assignment for a stable acetaldehyde-lysine adduct
    • Braun KP, Cody RB, Jones DR, Peterson CM. A structural assignment for a stable acetaldehyde-lysine adduct. J Biol Chem 1995;270:11263-6.
    • (1995) J Biol Chem , vol.270 , pp. 11263-11266
    • Braun, K.P.1    Cody, R.B.2    Jones, D.R.3    Peterson, C.M.4
  • 40
    • 0029879805 scopus 로고    scopus 로고
    • The formation and stability of imidazolidinone adducts from acetaldehyde and model peptides. A kinetic study with implications for protein modification in alcohol abuse
    • Fowles LF, Beck E, Worrall S, Shanley BC, de Jersey J. The formation and stability of imidazolidinone adducts from acetaldehyde and model peptides. A kinetic study with implications for protein modification in alcohol abuse. Biochem Pharmacol 1996;51:1259-67.
    • (1996) Biochem Pharmacol , vol.51 , pp. 1259-1267
    • Fowles, L.F.1    Beck, E.2    Worrall, S.3    Shanley, B.C.4    De Jersey, J.5
  • 41
    • 0031035993 scopus 로고    scopus 로고
    • Stable acetaldehyde adducts: Structural characterization of acetaldehyde adducts of human hemoglobin N-terminal beta-globin chain peptides
    • Braun KP, Pavlovich JG, Jones DR, Peterson CM. Stable acetaldehyde adducts: structural characterization of acetaldehyde adducts of human hemoglobin N-terminal beta-globin chain peptides. Alcohol Clin Exp Res 1997;21:40-3.
    • (1997) Alcohol Clin Exp Res , vol.21 , pp. 40-43
    • Braun, K.P.1    Pavlovich, J.G.2    Jones, D.R.3    Peterson, C.M.4
  • 42
    • 0027321834 scopus 로고
    • Production of antibodies that recognize the heterogeneity of immunoreactive sites in human hemoglobin chemically modified by acetaldehyde
    • Lin RC, Shahidi S, Lumeng L. Production of antibodies that recognize the heterogeneity of immunoreactive sites in human hemoglobin chemically modified by acetaldehyde. Alcohol Clin Exp Res 1993;17:882-6.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 882-886
    • Lin, R.C.1    Shahidi, S.2    Lumeng, L.3
  • 43
    • 0027903423 scopus 로고
    • Human blood acetaldehyde (updated 1992)
    • Eriksson CJP, Fukunaga T. Human blood acetaldehyde (updated 1992). Alcohol Alcohol 1993;Suppl 2:9-25.
    • (1993) Alcohol Alcohol , vol.2 , Issue.SUPPL. , pp. 9-25
    • Eriksson, C.J.P.1    Fukunaga, T.2
  • 44
    • 0020536806 scopus 로고
    • Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics
    • Nuutinen H, Lindros KO, Salaspuro M. Determinants of blood acetaldehyde level during ethanol oxidation in chronic alcoholics. Alcohol Clin Exp Res 1983;7:163-8.
    • (1983) Alcohol Clin Exp Res , vol.7 , pp. 163-168
    • Nuutinen, H.1    Lindros, K.O.2    Salaspuro, M.3
  • 45
    • 0035894063 scopus 로고    scopus 로고
    • Distribution of ethanol-induced protein adducts in vivo: Relationship to tissue injury
    • Niemelä O. Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury. Free Rad Biol Med 2001;31:1533-8.
    • (2001) Free Rad Biol Med , vol.31 , pp. 1533-1538
    • Niemelä, O.1
  • 46
    • 0030001945 scopus 로고    scopus 로고
    • Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration
    • Tuma DJ, Thiele GM, Xu D, Klassen LW, Sorrell MF. Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration. Hepatology 1996;23:872-80.
    • (1996) Hepatology , vol.23 , pp. 872-880
    • Tuma, D.J.1    Thiele, G.M.2    Xu, D.3    Klassen, L.W.4    Sorrell, M.F.5
  • 47
    • 0027310211 scopus 로고
    • Effect of ethanol on cytochrome P450 (CYP2E1), lipid peroxidation and serum protein adduct formation in relation to liver pathology
    • French SW, Wong K, Jui L, Albano E, Hagbjörk A-L, Ingelman-Sundberg M. Effect of ethanol on cytochrome P450 (CYP2E1), lipid peroxidation and serum protein adduct formation in relation to liver pathology. Exp Mol Pathol 1993;58:61-75.
    • (1993) Exp Mol Pathol , vol.58 , pp. 61-75
    • French, S.W.1    Wong, K.2    Jui, L.3    Albano, E.4    Hagbjörk, A.-L.5    Ingelman-Sundberg, M.6
  • 48
    • 0023019235 scopus 로고
    • Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo
    • Wickramasinghe SN, Gardner B, Barden G. Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo. Lancet 1986;ii:823-6.
    • (1986) Lancet , vol.2 , pp. 823-826
    • Wickramasinghe, S.N.1    Gardner, B.2    Barden, G.3
  • 49
    • 0023441606 scopus 로고
    • Improved method for acetaldehyde in plasma and hemoglobin-associated acetaldehyde: Results in teetotalers and alcoholics reporting for treatment
    • Peterson CM, Polizzi CM. Improved method for acetaldehyde in plasma and hemoglobin-associated acetaldehyde: results in teetotalers and alcoholics reporting for treatment. Alcohol 1987;4:477-80.
    • (1987) Alcohol , vol.4 , pp. 477-480
    • Peterson, C.M.1    Polizzi, C.M.2
  • 51
    • 0028352955 scopus 로고
    • Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation
    • Niemelä O, Parkkila S, Ylä-Herttuala S, et al. Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation. Lab Invest 1994;70:537-46.
    • (1994) Lab Invest , vol.70 , pp. 537-546
    • Niemelä, O.1    Parkkila, S.2    Ylä-Herttuala, S.3
  • 52
    • 0021691725 scopus 로고
    • Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: Generation of antibodies specific for the derivatized lysine
    • Steinbrecher UP, Fisher M, Witztum JL, Curtiss LK. Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: generation of antibodies specific for the derivatized lysine. J Lipid Res 1984;25:1109-16.
    • (1984) J Lipid Res , vol.25 , pp. 1109-1116
    • Steinbrecher, U.P.1    Fisher, M.2    Witztum, J.L.3    Curtiss, L.K.4
  • 53
    • 0023156031 scopus 로고
    • Acetaldehyde binding increases the catabolism of rat serum low-density lipoprotein
    • Savolainen MJ, Baraona E, Lieber CS. Acetaldehyde binding increases the catabolism of rat serum low-density lipoprotein. Life Sci 1987;40:841-6.
    • (1987) Life Sci , vol.40 , pp. 841-846
    • Savolainen, M.J.1    Baraona, E.2    Lieber, C.S.3
  • 54
    • 0027324521 scopus 로고
    • Acetaldehyde adducts and autoantibodles against VLDL and LDL in alcoholics
    • Wehr H, Rodo M, Lieber CS, Baraona E. Acetaldehyde adducts and autoantibodles against VLDL and LDL in alcoholics. J Lipid Res 1993;34:1237-44.
    • (1993) J Lipid Res , vol.34 , pp. 1237-1244
    • Wehr, H.1    Rodo, M.2    Lieber, C.S.3    Baraona, E.4
  • 55
    • 0035192722 scopus 로고    scopus 로고
    • Assays for acetaldehyde-derived adducts in blood proteins based on antibodies against acetaldehyde-lipoprotein condensates
    • Latvala J, Melkko J, Parkkila S, Järvi K, Makkonen K, Niemelä O. Assays for acetaldehyde-derived adducts in blood proteins based on antibodies against acetaldehyde-lipoprotein condensates. Alcohol Clin Exp Res 2001;25:1648-53.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1648-1653
    • Latvala, J.1    Melkko, J.2    Parkkila, S.3    Järvi, K.4    Makkonen, K.5    Niemelä, O.6
  • 56
    • 0028915927 scopus 로고
    • Serum low density lipoprotein of alcoholic patients is chemically modified in vivo and induces apolipoprotein e synthesis by macrophages
    • Lin RC, Dai J, Lumeng L, Zhang M. Serum low density lipoprotein of alcoholic patients is chemically modified in vivo and induces apolipoprotein E synthesis by macrophages. J Clin Invest 1995;95:1979-86.
    • (1995) J Clin Invest , vol.95 , pp. 1979-1986
    • Lin, R.C.1    Dai, J.2    Lumeng, L.3    Zhang, M.4
  • 57
    • 0025806044 scopus 로고
    • Immunohistochemical demonstration of acetaldehyde modified epitopes in human liver after alcohol consumption
    • Niemelä O, Juvonen T, Parkkila S. Immunohistochemical demonstration of acetaldehyde modified epitopes in human liver after alcohol consumption. J Clin Invest 1991;87:1367-74.
    • (1991) J Clin Invest , vol.87 , pp. 1367-1374
    • Niemelä, O.1    Juvonen, T.2    Parkkila, S.3
  • 58
    • 0029160569 scopus 로고
    • Experimental liver disease induced by alcohol and iron
    • Tsukamoto H, Home W, Kamimura S, et al. Experimental liver disease induced by alcohol and iron. J Clin Invest 1995;96:620-30.
    • (1995) J Clin Invest , vol.96 , pp. 620-630
    • Tsukamoto, H.1    Home, W.2    Kamimura, S.3
  • 59
    • 0029125812 scopus 로고
    • Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol induced liver disease
    • Niemelä O, Parkkila S, Ylä-Herttuala S, Villanueva J, Ruebner B, Halsted C. Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol induced liver disease. Hepatology 1995;22:1208-14.
    • (1995) Hepatology , vol.22 , pp. 1208-1214
    • Niemelä, O.1    Parkkila, S.2    Ylä-Herttuala, S.3    Villanueva, J.4    Ruebner, B.5    Halsted, C.6
  • 60
    • 0037162531 scopus 로고    scopus 로고
    • Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig
    • Halsted CH, Villanueva JA, Devlin AM, et al. Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci USA 2002;99:10072-7.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10072-10077
    • Halsted, C.H.1    Villanueva, J.A.2    Devlin, A.M.3
  • 61
    • 0024406375 scopus 로고
    • Acetaldehyde substoichiometrically inhibits bovine neurotubulin polymerization
    • Smith SL, Jennett RB, Sorrell MF, Tuma DJ. Acetaldehyde substoichiometrically inhibits bovine neurotubulin polymerization. J Clin Invest 1989;84:337-41.
    • (1989) J Clin Invest , vol.84 , pp. 337-341
    • Smith, S.L.1    Jennett, R.B.2    Sorrell, M.F.3    Tuma, D.J.4
  • 62
    • 0022633847 scopus 로고
    • Covalent binding of acetaldehyde selectively inhibits the catalytic activity of lysine dependent enzymes
    • Mauch TJ, Donohue TM, Zettermann RK, Sorrell MF, Tuma DJ. Covalent binding of acetaldehyde selectively inhibits the catalytic activity of lysine dependent enzymes. Hepatology 1986;6:263-9.
    • (1986) Hepatology , vol.6 , pp. 263-269
    • Mauch, T.J.1    Donohue, T.M.2    Zettermann, R.K.3    Sorrell, M.F.4    Tuma, D.J.5
  • 63
    • 0023634974 scopus 로고
    • The reaction of acetaldehyde with brain microtubular proteins: Formation of stable adducts and inhibition of polymerization
    • McKinnon G, de Jersey J, Shanley B, Ward L. The reaction of acetaldehyde with brain microtubular proteins: formation of stable adducts and inhibition of polymerization. Neurosci Lett 1987;79:163-8.
    • (1987) Neurosci Lett , vol.79 , pp. 163-168
    • McKinnon, G.1    De Jersey, J.2    Shanley, B.3    Ward, L.4
  • 64
    • 0023078219 scopus 로고
    • The binding of acetaldehyde to the active site of ribonuclease: Alterations in catalytic activity and effects of phosphate
    • Mauch TJ, Tuma DJ, Sorrell MF. The binding of acetaldehyde to the active site of ribonuclease: alterations in catalytic activity and effects of phosphate. Alcohol 1987;22:103-12.
    • (1987) Alcohol , vol.22 , pp. 103-112
    • Mauch, T.J.1    Tuma, D.J.2    Sorrell, M.F.3
  • 65
    • 0028040337 scopus 로고
    • Acetaldehyde activates the promoter of the mouse α2(I) collagen gene
    • Pares A, Potter JJ, Rennie L, Mezey E. Acetaldehyde activates the promoter of the mouse α2(I) collagen gene. Hepatology 1994;19:498-503.
    • (1994) Hepatology , vol.19 , pp. 498-503
    • Pares, A.1    Potter, J.J.2    Rennie, L.3    Mezey, E.4
  • 66
    • 0023637142 scopus 로고
    • Acetaldehyde increases collagen gene transcription in cultured human fibroblasts
    • Brenner DA, Chojkier M. Acetaldehyde increases collagen gene transcription in cultured human fibroblasts. J Biol Chem 1987;262:17690-5.
    • (1987) J Biol Chem , vol.262 , pp. 17690-17695
    • Brenner, D.A.1    Chojkier, M.2
  • 67
    • 0025752432 scopus 로고
    • Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism
    • Casini A, Cunningham M, Rojkind M, Lieber CS. Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991;13:758-65.
    • (1991) Hepatology , vol.13 , pp. 758-765
    • Casini, A.1    Cunningham, M.2    Rojkind, M.3    Lieber, C.S.4
  • 68
    • 20644453966 scopus 로고    scopus 로고
    • Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: Relationship to liver disease severity and alcohol consumption
    • Viitala K, Blake JE, Israel Y, Niemelä O. Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption. Hepatology 1997;25:1418-24.
    • (1997) Hepatology , vol.25 , pp. 1418-1424
    • Viitala, K.1    Blake, J.E.2    Israel, Y.3    Niemelä, O.4
  • 69
    • 0023783509 scopus 로고
    • The role of alcoholism and liver disease in the appearance of serum antibodies against acetaldehyde adducts
    • Hoerner M, Behrens UJ, Worner TM, et al. The role of alcoholism and liver disease in the appearance of serum antibodies against acetaldehyde adducts. Hepatology 1988;8:569-74.
    • (1988) Hepatology , vol.8 , pp. 569-574
    • Hoerner, M.1    Behrens, U.J.2    Worner, T.M.3
  • 70
    • 0026480540 scopus 로고
    • Immunoglobulin a antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis
    • Koskinas J, Kenna JG, Bird GL, Alexander GJM, Williams R. Immunoglobulin A antibody to a 200-kilodalton cytosolic acetaldehyde adduct in alcoholic hepatitis. Gastroenterology 1992;103:1860-7.
    • (1992) Gastroenterology , vol.103 , pp. 1860-1867
    • Koskinas, J.1    Kenna, J.G.2    Bird, G.L.3    Alexander, G.J.M.4    Williams, R.5
  • 71
    • 0023927684 scopus 로고
    • Immune responses to alcohol metabolites: Pathogenic and diagnostic implications
    • Israel Y, Orrego H, Niemelä O. Immune responses to alcohol metabolites: pathogenic and diagnostic implications. Semin Liver Dis 1988;8:81-90.
    • (1988) Semin Liver Dis , vol.8 , pp. 81-90
    • Israel, Y.1    Orrego, H.2    Niemelä, O.3
  • 72
    • 0024791159 scopus 로고
    • Clinical significance of serum antibodies against alcohol-altered hepatocyte membrane in alcoholic liver disease
    • Izumi N, Sakai Y, Koyama W, Hasumura, Y. Clinical significance of serum antibodies against alcohol-altered hepatocyte membrane in alcoholic liver disease. Alcohol Clin Exp Res 1989;13:762-5.
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 762-765
    • Izumi, N.1    Sakai, Y.2    Koyama, W.3    Hasumura, Y.4
  • 73
  • 74
    • 0026022852 scopus 로고
    • Antibodies against acetaldehyde-modified epitopes: An elevated IgA response in alcoholics
    • Worrall S, de Jersey J, Shanley BC, Wilce PA. Antibodies against acetaldehyde-modified epitopes: an elevated IgA response in alcoholics. Eur J Clin Invest 1991;21:90-5.
    • (1991) Eur J Clin Invest , vol.21 , pp. 90-95
    • Worrall, S.1    De Jersey, J.2    Shanley, B.C.3    Wilce, P.A.4
  • 75
    • 0033861032 scopus 로고    scopus 로고
    • Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers
    • Viitala K, Makkonen K, Israel Y, et al. Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers. Alcohol Clin Exp Res 2000;24:1103-9.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1103-1109
    • Viitala, K.1    Makkonen, K.2    Israel, Y.3
  • 77
    • 17544373959 scopus 로고    scopus 로고
    • Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease
    • Rolla R, Vay D, Mottaran E, et al. Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease. Hepatology 2000;31:878-84.
    • (2000) Hepatology , vol.31 , pp. 878-884
    • Rolla, R.1    Vay, D.2    Mottaran, E.3
  • 79
    • 0026632511 scopus 로고
    • Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: Comparison of two new methods
    • Sillanaukee P, Seppä K, Koivula T, Israel Y, Niemelä O. Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods. J Lab Clin Med 1992;120:42-7.
    • (1992) J Lab Clin Med , vol.120 , pp. 42-47
    • Sillanaukee, P.1    Seppä, K.2    Koivula, T.3    Israel, Y.4    Niemelä, O.5
  • 80
    • 0029150858 scopus 로고
    • Validated fluorimetric HPLC analysis of acetaldehyde in hemoglobin fractions separated by cation exchange chromatography: Three new peaks associated with acetaldehyde
    • Chen HM, Scott BK, Braun KP, Peterson CM. Validated fluorimetric HPLC analysis of acetaldehyde in hemoglobin fractions separated by cation exchange chromatography: three new peaks associated with acetaldehyde. Alcohol Clin Exp Res 1995;19:939-44.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 939-944
    • Chen, H.M.1    Scott, B.K.2    Braun, K.P.3    Peterson, C.M.4
  • 81
    • 0027080758 scopus 로고
    • The identification and partial characterization of acetaldehyde adducts of hemoglobin occurring in vivo: A possible marker of alcohol consumption
    • Gross MD, Gapstur SM, Belcher JD, Scarlan G, Potter JD. The identification and partial characterization of acetaldehyde adducts of hemoglobin occurring in vivo: a possible marker of alcohol consumption. Alcohol Clin Exp Res 1992;16:1093-7.
    • (1992) Alcohol Clin Exp Res , vol.16 , pp. 1093-1097
    • Gross, M.D.1    Gapstur, S.M.2    Belcher, J.D.3    Scarlan, G.4    Potter, J.D.5
  • 84
    • 0026327695 scopus 로고
    • Hemoglobin-acetaldehyde adducts are elevated in women with alcohol-damaged fetuses
    • Niemelä O, Halmesmäki E, Ylikorkala O. Hemoglobin-acetaldehyde adducts are elevated in women with alcohol-damaged fetuses. Alcohol Clin Exp Res 1991;15:1007-10.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 1007-1010
    • Niemelä, O.1    Halmesmäki, E.2    Ylikorkala, O.3
  • 85
    • 0034064243 scopus 로고    scopus 로고
    • Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse
    • Sarkola T, Eriksson CJP, Niemelä O, Sillanaukee P, Halmesmäki E. Mean cell volume and gamma-glutamyl transferase are superior to carbohydrate-deficient transferrin and hemoglobin-acetaldehyde adducts in the follow-up of pregnant women with alcohol abuse. Acta Obstet Gynecol Scand 2000;79:359-66.
    • (2000) Acta Obstet Gynecol Scand , vol.79 , pp. 359-366
    • Sarkola, T.1    Eriksson, C.J.P.2    Niemelä, O.3    Sillanaukee, P.4    Halmesmäki, E.5


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