Transcriptional activation of the metallothionein I gene by electric pulses in vivo: Basis for the development of a new gene switch system

Journal of Gene Medicine

Volumn 5, Issue 9, 2003, Pages 773-783

  Rubenstrunk, Anne ^a   Orsini, Cécile ^a   Mahfoudi, Abderrahim ^a   Scherman, Daniel ^a,b  

^a SANOFI   (France)

^b CNRS   (France)

Author keywords

Electrotransfer; Gene regulation; Gene therapy; Inducible promoter; Metallothionein I; Muscle

Indexed keywords

MESSENGER RNA; METALLOTHIONEIN; METALLOTHIONEIN I; REGULATOR PROTEIN; CALCIPHORIN; CALCIUM BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRIC FIELD; ELECTROSTIMULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE SWITCHING; GENE TRANSFER; GENETIC ANALYSIS; IN VIVO STUDY; MOUSE; MUSCLE DISEASE; NONHUMAN; NORTHERN BLOTTING; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAFETY; SKELETAL MUSCLE; STIMULUS RESPONSE; TIME; TRANSCRIPTION INITIATION; ANIMAL; ELECTROPORATION; GENE VECTOR; GENETICS; INTRAMUSCULAR DRUG ADMINISTRATION; METABOLISM; METHODOLOGY; TRANSACTIVATION;

ANIMALS; CALCIUM-BINDING PROTEINS; ELECTROPORATION; GENE EXPRESSION REGULATION; GENETIC VECTORS; INJECTIONS, INTRAMUSCULAR; METALLOTHIONEIN; MICE; MUSCLE, SKELETAL; PLASMIDS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRANS-ACTIVATION (GENETICS);

EID: 2342448685     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.360     Document Type: Article

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