DNA replication: Building the perfect switch

Current Biology

Volumn 11, Issue 9, 2001, Pages

  Diffley, John F X ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0035336803     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00196-8     Document Type: Review

References (30)

1. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
2. Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
3. Eukaryotic DNA replication: From pre-replication complex to initiation complex
4. XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
5. The Cdt1 protein is required to license DNA for replication in fission yeast
6. Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?
7. Once and only once upon a time: Specifying and regulating origins of DNA replication in eukaryotic cells
8. Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis
9. The cyclin dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle
10. The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae
11. G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus
12. Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7
13. Whose end is destruction: Cell division and the anaphase-promoting complex
14. Geminin, an inhibitor of DNA replication, is degraded during mitosis
15. Purification of an MCM-containing complex as a component of the DNA replication licensing system
16. A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle
17. Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its subcellular localization
18. Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
19. Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle
20. Sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast
21. Cdc18 transcription and proteolysis couple S phase to passage through mitosis
22. F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p
23. Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18
24. Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
25. Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
26. CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis
27. APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
28. Cell cycle regulation of DNA replication initiator factor Dbf4p
29. Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability
30. Dbf4p, an essential S phase promoting factor, is targeted for degradation by the anaphase promoting complex