Agastache rugosa leaf extract inhibits the iNOS expression in ROS 17/2.8 cells activated with TNF-α and IL-1β

Archives of Pharmacal Research

Volumn 28, Issue 3, 2005, Pages 305-310

  Hwa, Min Oh ^a   Young, Jin Kang ^a   Sun, Hee Kim ^a   Young, Soo Lee ^a   Min, Kyu Park ^a   Ja, Myung Heo ^a   Jin, Ji Sun ^a   Hyo, Jung Kim ^a   Eun, Sil Kang ^a   Hye, Jung Kim ^a   Han, Geuk Seo ^a   Jae, Heun Lee ^a   Yun Choi, Hye Sook ^b   Ki, Churl Chang ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Agastache rugosa; Bone turn over; Nitric oxide; Osteoarthritis; Osteoblast

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, RAT; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

AGASTACHE; ANIMAL; ARTICLE; BIOSYNTHESIS; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; OSTEOBLAST; PHYSIOLOGY; PLANT LEAF; PROTEIN TRANSPORT; RAT; TUMOR CELL LINE;

AGASTACHE; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; INTERLEUKIN-1; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOBLASTS; PLANT EXTRACTS; PLANT LEAVES; PROTEIN TRANSPORT; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23344434227     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/bf02977797     Document Type: Article

References (29)

1. Armour, K. J., Armour, K. E., VanT Hof, R. J., Reid, D. M., Wei, X. Q., Liew, F. Y., and Ralston, S. H., Activation of the inducible nitric oxide synthase pathway contributes to inflammation induced osteoporosis by suppressing bone formation and causing osteoblast apoptosis. Arthritis Rheum., 44, 2790-2796 (2001).
2. Armour, K. E., VanT Hof, R. J., Grabowski, P. S., Reid, D. H., and Ralston, S. H., Evidence for a pathogenic role of nitric oxide in inflammation-induced osteoblast. J. Bone Miner. Res., 14, 2137-2142 (1999).
3. Bertolini, D. R., Nedwin, G. E., Bringman, T. S., Smith, D. D., and Mundy, G. R., Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature, 319, 6-8 (1986).
4. Boileau, C., Martel-Pelletier, J., Moldovan, F., Jouzeau, J. Y., Netter, P., Manning, P. T., and Pelletier, J. P., The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide. Arthritis Rheum., 46, 2637-2647 (2002).
5. Chae, H. J., Chae, S. W., Kang, J. S., Bang, B. G., Cho, S. B., Park, R. K., So, H. S., Kim, Y. K., Kim, H. M., and Kim, H. R., Dexamethasone suppresses tumor necrosis factor-alpha-induced apoptosis in osteoblasts: possible role for ceramide. Endocrinology, 141, 2904-2913 (2000a).
6. Chae, H. J., Kang, J. S., Byun, J. O., Han, K. S., Kim, D. U., Oh, S. M., Kim, H. M., Chae, S. W., and Kim, H. R., Molecular mechanism of staurosporine-induced apoptosis in osteoblasts. Pharmacol. Res., 42, 373-381 (2000b).
7. Gowen, M., Wood, D. D., Ihrie, E. J., McGuire, M. K., and Russell, R. G., An interleukin 1 like factor stimulates bone resorption in vitro. Nature, 306, 378-380 (1983).
8. Grabowski, P. S., England, A. J., Dykhuizen, R., Copland, M., Benjamin, N., Reid, D. M., and Ralston, S.H., Elevated nitric oxide production in rheumatoid arthritis. Detection using the fasting urinary nitrate:creatinine ratio. Arthritis Rheum., 39, 643-647 (1996).
9. Green, L. C., De Luzuriaga, K. R., Wagner, D. A., Rand, W., Istfan, N., Young, V. R., and Tannenbaum, S. R., Nitrate biosynthesis in the germfree and conventional rat. Science (Wash DC), 212, 56-68 (1981).
10. Hukkanen, M., Hughes, F. J., Buttery, L. D., Gross, S. S., Evans, T. J., Seddon, S., Riveros-Moreno, V., Macintyre, I., and Polak, J. M., Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat, and human osteoblast-like cells and its functional role in osteoblast metabolic activity. Endocrinology, 136, 5445-5453 (1995).
11. Ihbe, A., Baumann, G., Heinzmann, U., and Atkinson, M. J., Loss of the differentiated phenotype precedes apoptosis of ROS 17/2.8 osteoblast-like cells. Calcif. Tissue Int., 63, 208-213 (1998).
12. Jilka, R. L., Weinstein, R. S., Bellido, T., Parfitt, A. M., and Manolagas, S. C., Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines. J.Bone Miner. Res., 13, 793-802 (1998).
13. Kang, Y. J., Koo, E. B., Lee, Y. S., Yun-Choi, H. S., and Chang, K. C., Prevention of the expression of inducible nitric oxide synthase by a novel positive inotropic agent, YS 49, in rat vascular smooth muscle and RAW 264.7 macrophages. Br. J. Pharmacol., 128, 357-364 (1999).
14. Kitajima, I., Nakajima, T., Imamura, T., Takasaki, I., Kawahara, K., Okano, T., Tokioka, T., Soejima, Y., Abeyama, K., and Maruyama, I., Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha. J. Bone Miner. Res., 11, 200-210 (1996).
15. Kim, H. K., Lee, H. K., Shin, C. G., and Huh, H., HIV integrase inhibitory activity of Agastache rugosa. Arch. Pharm. Res., 22, 520-523 (1999).
16. Lee, C. H , Kim, H. N., and Kho, K. E., Agastinol and agastenol, novel ligans from Agastache rugosa and their evaluation in an apoptosis inhibition assay. J. Nat. Prod., 65, 414-416 (2002).
17. Lin, S. K., Kok, S. H., Kuo, M. Y,. Lee, M. S., Wang, C. C., Lan, W. H., Hsiao, M., Goldring, S. R., and Hong, C. Y., Nitric oxide promotes infectious bone resorption by enhancing cytokin-stimulated interstitial collagenase synthesis in osteoblasts. J. Bone Miner. Res., 18, 39-46 (2003).
18. Niederberger, E., Tegeder, I., Schafer, C., Seegel, M., Grosch, S., and Geisslinger, G., Opposite effects of rofecoxib on nuclear factor-kappaB and activating protein-1 activation. J. Pharmacol. Exp. Ther., 304, 1153-1160 (2003).
19. Marpherson, H., Noble, B. S., and Ralston, S. H., Expression and functional role of nitric oxide synthase isoforms in human osteoblast-like cells. Bone, 24, 179-185 (1999).
20. Mcsheehy, P. M. and Chambers, T. J., Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone. Endocrinology, 118, 824-828 (1986).
21. Mogi, M., Kinpara, K., Kondo, A., and Togari, A., Involvement of nitric oxide and biopterin in proinflammatory cytokine-induced apoptotic cell death in mouse osteoblastic cell line MC3T3-E1. Biochem. Pharmacol., 58, 649-654 (1999).
22. Mogi, M., Kondo, A., Kinpara, K., and Togari, A., Anti-apoptotic action of nerve growth factor in mouse osteoblastic cell line. Life Sci., 67, 1197-1206 (2000).
23. Pelletier, J. P., Fernande,s J. C., Jovanovic, D. V., Reboul, P., and Martel-Pelletier, J., Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase. J. Rheumatol., 11, 2509-2519 (2001).
24. Rodan, G. A. and Noda, M., Gene expression in osteoblastic cells. Crit. Rev. Eukaryot. Gene Expr., 1, 85-98 (1991).
25. Sandhu, J. K., Robertson, S., Birnboim, H. C., and Goldstein, R., Distribution of protein nitrotyrosine in synovial tissues of patients with rheumatoid arthritis and osteoarthritis. J. Rheumatol., 30, 1173-1181 (2003).
26. Shin, S., Essential oil compounds from Agastache rugosa as antifungal agents against Trichophyton species. Arch. Pharm. Res., 27, 295-299 (2004).
27. Wang, E. A., Rosen, V., DAlessandro, J. S., Bauduy, M., Cordes, P., Harada, T., Israel, D. I., Hewick, R. M., Kerns, K. M., LaPan, P., Luxenberg, D. P., McQuaid, D., Moutsatsos, K. I., Nove, J., and Wozney, J. M., Recombinant human bone morphogenetic protein induces bone formation. Proc. Natl. Acad. Sci. U.S.A., 87, 2220-2224 (1990).
28. Wetterwald, A., Hoffstetter, W., Cecchini, M. G., Lanske, B., Wagner, C., Fleisch, H., and Atkinson, M., Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone, 18, 125-132 (1996).
29. Yamaguchi, A., Katagiri, T., Ikeda, T., Wozney, J. M., Rosen, V., Wang, E. A., Kahn, A. J., Suda, T., and Yoshiki, S., Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J. Cell Biol., 113, 681-687 (1991).