HIV integrase inhibitory activity of Agastache rugosa

Archives of Pharmacal Research

Volumn 22, Issue 5, 1999, Pages 520-523

  Kim, Hye Kyong ^a   Lee, Hyeong Kyu ^b   Shin, Cha Gyun ^c   Huh, Hoon ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

Agastache rugosa; HIV integrase; Labiatae; Rosmarinic acid

Indexed keywords

CINNAMIC ACID DERIVATIVE; DEPSIDE; INTEGRASE; INTEGRASE INHIBITOR; PLANT EXTRACT; RECOMBINANT PROTEIN; ROSMARINIC ACID;

ANGIOSPERM; ARTICLE; BIOSYNTHESIS; CHEMISTRY; ESCHERICHIA COLI; HUMAN; IN VITRO STUDY; ISOLATION AND PURIFICATION; KOREA; METABOLISM; ORIENTAL MEDICINE; PHYTOTHERAPY; PLANT ROOT; SOLUBILITY;

CINNAMATES; DEPSIDES; ESCHERICHIA COLI; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; KOREA; LAMIACEAE; MEDICINE, ORIENTAL TRADITIONAL; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RECOMBINANT PROTEINS; SOLUBILITY;

EID: 0033203241     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02979163     Document Type: Article

References (16)

1. Fesen, M. R., Kohn, K. W., Leteurtre, F. and Pommier, Y., Inhibitors of human immunodeficiency virus integrase. Proc. Natl. Acad. Sci. USA. 90, 2399-2403 (1993).
2. Fesen, M. R., Pommier, Y., Leteurtre, F., Hiroguchi, S., Yung, J. and Kohn, K. W., Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 48, 595-608 (1994)
3. Han, D. S., Kim, Y. C., Kim, S. E., Ju, H. S. and Byun, S. J., Studies of the diterpene constituent of the root of Agastache rugosa O. Kuntze, Kor. J. Pharmacogn. 18, 99-102 (1987).
4. Han, D. S., Triterpenes from the root of Agastache rugosa, Kor. J. Pharmacogn. 18, 50-53 (1987).
5. Kelly, C. J., Harruff, R. C. and Carmack, M., The polyphenolic acids of Lithospermum ruderale. II. Carbon-13 nuclear magnetic resonance of lithospermic and rosmarinic acids, J. Org. Chem. 41, 449-455 (1976).
6. Kelly, C. J., Mahajan, J. R., Brooks, L. C., Neubert, L. A., Breneman W. R. and Carmack, M., Polyphenolic acids from Lithospermum ruderale Dougl. ex Lehm. (Boraginaceae). 1. Isolation and structure determination of lithospermic acid, J. Org. Chem. 40, 1804-1815 (1975).
7. Kim, H. J., Woo, E-R., Shin, C-G. and Park, H., A new flavol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus (HIV-1) integrase, J. Nat. Prod. 61, 145-148 (1998).
8. Kuhnt, M., Rimpler, H. and Heinrich, M., Lignans and other compounds from the mixture Indian medicinal plant Hyptis verticillata, Phytochem. 36, 485-489 (1994).
9. Lee, H. K., Oh, S. R., Kim, J. I., Kim, J. and Lee, C., Agastaquinone, a new cytotoxic diterpenoid quinone from Agastache rugosa, J. Nat. Prod., 58, 1718-1721 (1995).
10. Lee, S. J., Korean Folk Medicine, Seoul Prints, Seoul, p 113 (1976).
11. Mazumder, A., Neamati, N., Sunder, S., Schulz, J., Pertz, H., Leteurtre, E. and Pommier, Y., Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action. J. Med. Chem. 40, 3057-3063 (1997)
12. Mazumder, A., Raghavan, K., Weinstein, J., Kohn, K. W. and Pommier, Y., Inhibition of human immunodeficiency virus type-1 integrase by curcumin. Biochem. Pharmacol. 49, 1165-1170 (1995)
13. Oh, J.-W. and Shin, C.-G., Purification and characterization of the human immunodeficiency virus type 1 integrase expressed in Escherichia coli, Mol. Cell, 6, 96-100 (1996).
14. Oh, Y.-T. and Shin, C.-G., Comparison of enzymatic activities of the HIV-1 and HFV integrases to their U5 LTR substrates. Biochem. Mol. Biol. Int., 47, 621-629 (1999).
15. Pearson, D. A., Frankel, E. N., Aeschbach, R. and German, J. B., Inhibition of endothelial cell-mediated oxidation of low-density lipoprotein by rosmary and plant phenolics, J. Agric. Food Chem. 45, 578-582 (1997).
16. Sherman, P. A. and Fyfe, J. A., Human immunodeficiency virus integrase protein expressed in Escherichia coli possesses selective DNA cleavaging activity. Proc. Natl. Acad. Sci. USA 87, 5119-5123 (1990).