Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-κB and TNF-α

Journal of Bone and Mineral Research

Volumn 11, Issue 2, 1996, Pages 200-210

  Kitajima, Isao ^a,b   Nakajima, Toshihiro ^a   Imamura, Takeshi ^a   Takasaki, Ikuko ^a   Kawahara, Koichi ^a   Okano, Toshihiro ^a   Tokioka, Takeshi ^a   Soejima, Yasuko ^a   Abeyama, Kazuhiro ^a   Maruyama, Ikuro ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; NUCLEAR FACTOR; TAX PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE REMODELING; CELL CLONE; CELL GROWTH; CULTURE MEDIUM; GROWTH INHIBITION; HUMAN T CELL LEUKEMIA VIRUS 1; LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; OSTEOBLAST; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGEN-ANTIBODY REACTIONS; APOPTOSIS; CLONE CELLS; COCULTURE TECHNIQUES; CULTURE MEDIA; CYTOKINES; GENE PRODUCTS, TAX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; MICE; NF-KAPPA B; OSTEOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030040554     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650110209     Document Type: Article

References (54)

1. Uchiyama T, Yodoi J, Sagawa K, Takatsuki K, Uchino H 1977 Adult T cell leukemia: clinical and hematologic features of 16 cases. Blood 50:481-492.
2. Yoshida M, Miyoshi I, Hinuma Y 1982 Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci USA 79:2031-2035.
3. Bunn PA Jr, Schechter GP, Jaffe E, Blayney D, Young RC. Matthews MJ, Blattner W, Broder S, Robert-Guroff M, Gallo RC 1983 Clinical course of retrovirus-associated adult T-cell lymphoma in the United States. New Engl J Med 309:257-269.
4. Kiyokawa T, Yamaguchi K, Takeya M, Takahashi K, Watanabe T, Matsumoto T, Lee SY, Takatsuki K 1987 Hypercalcemia and osteoclast proliferation in adult T-cell leukemia. Cancer 59:1187-1191.
5. Motokura T, Fukumoto S, Matsumoto T, Takahashi S, Fujita A, Yamashita T, Igarashi T, Ogata E 1989 Parathyroid hormone-related protein in adult T-cell leukemia-lymphoma. Ann Intern Med 111:484-488.
6. Shirakawa F, Yamashita U, Tanaka Y, Watanabe K, Sato K, Hiratake J, Fujihira T, Oda O, Eto S 1988 Production of bone-resorbing activity corresponding to interleukin-1α by adult T-cell leukemia cells in humans. Cancer Res 48:4284-4287.
7. Albrecht H, Shakhov AN, Jongeneel CV 1992 Transactivation of the tumor necrosis factor alpha promoter by the human T-cell leukemia virus type I tax, protein. J Virol 66:6191-6193.
8. Sato K, Fujii Y, Kasono K, Ozawa M, Imamura H, Kanaji Y, Kurosawa H, Tsushima T, Shizume K 1989 Parathyroid hormone-related protein and interleukin-1 alpha synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in mice in vivo. Endocrinology 124: 2172-2178.
9. Parfitt AM 1982 The coupling of bone formation to bone resorption. A critical analysis of the concept and its relevance to the pathogenesis of osteoporosis. Metab Bone Dis Rel Res 4:1-6.
10. Nerenberg M, Hinrichs SH, Reynolds PK, Khouty G, Jay G 1987 The tat gene of human T-lymphotropic virus type I induced mesenchymal tumors in transgenic mice. Science 237: 1324-1329.
11. Kitajima I, Shinohara T, Minor T, Bibbs L, Bilakovics J, Nerenberg M 1992 Human T-cell leukemia virus type I tax transformation is associated with increased uptake of oligodeoxynucleotides in vitro and in vivo. J Biol Chem 267:25881-25888.
12. Tomita S, Ambrus L Jr, Volkman DJ, Longo DL, Mitsuya H, Reitz MS Jr, Fauti AS 1985 Human T cell leukemia/lymphoma virus type I infection and subsequent cloning of normal B cells. J Exp Med 162:393-398.
13. Toshikura H, Nishida J, Yoshida M, Kitamura Y, Takaku F, Ikeda S 1984 Isolation of HTLV-I derived from Japanese adult T cell leukemia patients in human diploid fibroblast strain IMR 90 and the biological characters of the infected cells. Int J Cancer 33:745-749.
14. Hu DD, Rota TR, Hirsch MS 1984 Infection of human endothelial cells by human T-lymphotropic virus type I. Proc Natl Acad Sci USA 81:7588-7590.
15. Clapham P, Nagy K, Cheingson-Popov R, Exley M, Weiss RA 1983 Productive infection and cell-free transmission of human T-cell leukemia virus in a nonlymphoid cell line. Science 222: 1125-1127.
16. Kitajima I, Yamamoto K, Sato K, Nakajima Y, Nakajima T, Maruyama I, Osame M, Nishioka K 1991 Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy. J Clin Invest 88:1315-1322.
17. Ishibashi K, Ishitsuka K, Chuman Y, Otsuka M, Kuwazuru Y, Iwahashi M, Utsunomiya A, Hanada S, Sakurami T, Arima T 1991 Tumor necrosis factor-β in the serum of adult T-cell leukemia with hypercalcemia. Blood 77:2451-2455.
18. Le J, Vilcek J 1987 Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab Invest 56:236-248.
19. Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino Jr MA, Shepard HM 1985 Recombinant human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science 230:943-945.
20. Centrella M, McCarthy TL, Canalis E 1988 Tumor necrosis factor-α inhibits collagen synthesis and alkaline phosphatase activity independently of its effect on deoxyribonucleic acid synthesis in osteoblast-enriched bone cell cultures. Endocrinology 123:1442-1448.
21. Rubin BY, Smith LJ, Hellermann GR, Lunn RM, Richardson NK, Anderson SL 1988 Correlation between the anticellular and DNA fragmenting activities of tumor necrosis factor. Cancer Res 48:6006-6010.
22. Baeuerle PA 1991 The inducible transcription activator NF-κB. Regulation by distinct protein subunits. Biochim Biophys Acta 1072:63-80.
23. 1 protein stimulates tumor necrosis factor-β and immunoglobulin kappa light chain expression in lymphoid cells. J Virol 66:1294-1298.
24. Sudo H, Kodama H, Amagai Y, Yamamoto S, Kasai S 1983 In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96:191-198.
25. Miyoshi I, Kubonishi I, Yoshimoto S, Akagi T, Ohtsuki Y, Shiraishi Y, Nagata K, Hinuma Y 1981 Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukemic T cells. Nature 249:770-771.
26. Reznikoff CA, Bertram JS, Brandow DW, Heidelberger C 1973 Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to post-confluence inhibition of cell division. Cancer Res 33:3239-3249.
27. Hoxie JA, Matthews, DM. Clines DB 1984 Infection of human endothelial cells with human T-cell leukemia virus type I. Proc Natl Acad Sci USA 81:7529-7535.
28. Mori K, Sabe H, Simoi H, lino T, Tanaka A, Takeuchi K, Hiravoshi K, Hatanaka M 1987 Expression of a provirus of human T cell leukemia virus type I by DNA transfection. J Gen Virol 68:499-506.
29. Taga K, Cherney B, Tosato G 1993 IL-10 inhibits apoptotic cell death in human T cells starved of IL-2. Int Immunol 5:1599-1608.
30. Mosmann T 1983 Rapid colorinmetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 65:55-63.
31. Kitajima I, Shinohara T, Bilakovics J, Brown D, Xu X, Nerenberg M 1992 Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-κB. Science 258:1792-1795.
32. Yamamoto N, Okada M, Koyanagi Y, Kannagi M, Hinuma Y 1982 Transformation of human leukocytes by cocultivation with T cell leukemia virus producer cell line. Science 217:737-739.
33. Sodroski JG, Rosen CA, Haseltine WA 1984 Transacting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells. Science 225:381-385.
34. tax of human T-cell leukemia virus type I in vitro. Proc Natl Acad Sci USA 87:1071-1075.
35. Debatin K-M, Goldman CK, Waldman TA, Krammer PH 1993 Apo-1-induced apoptosis of leukemia cells from patients with adult T-cell leukemia. Blood 81:2972-2977.
36. Tsuda H, Hung R-W, Takatsuki K 1993 Interleukin-2 prevents programmed cell death in adult T-cell leukemia cells. Jpn J Cancer Res 84:431-437.
37. Debatin K-M, Goldman CK, Bamford R, Waldman TA, Krammer PH 1990 Monoclonal-antibody-mediated apoptosis in adult T cell leukemia. Lancet 335:497.
38. Yamada T, Yamaoka S, Goto T, Nakai M, Tsujimoto Y, Hatanaka M 1994 The human T-cell leukemia virus type I tax protein induces apoptosis which is blocked by the Bcl-2 protein. J Virol 68:3374-3379.
39. Ishimi Y, Miyaura C, Jin CH, Akatsu T, Abe E, Nakamura Y, Yamaguchi A, Yoshiki S, Matsuda T, Hirano T, Kishimoto T, Suda T 1990 IL-6 is produced by osteoblasts and induces bone resorption. J Immunol 145:3297-3303.
40. Elias E, Moore PB, Rose SW 1989 Tumor necrosis factor induced DNA fragmentation of HL-60. Biochem Biophys Res Commun 163:867-873.
41. Elias E, Berry COA 1991 Induction of tumor necrosis factor in HL-60 cells is associated with the formation of large DNA fragments. Leukemia 5:879-885.
42. Greenblatt MS, Elias E 1992 The type B receptor for tumor necrosis factor-α mediates DNA fragmentation in HL-60 and U937 cells and differentiation in HL-60 cells. Blood 80:1339-1346.
43. Kyprianou N, Alexander RB, Isaacs JT 1991 Activation of programmed cell death by recombinant human tumor necrosis factor plus topoisomerase II-targeted drugs in L929 tumor cells. J Natl Cancer Inst 83:346-350.
44. Fehsel K, Kolb-Bachofen V, Kolb H 1991 Analysis of TNFα-induced DNA strand breaks at the single cell level. Am J Pathol 139:251-254.
45. Gromkowski SH, Mama K, Yagi J, Sen R, Rath S 1990 Double-stranded RNA and bacterial lipopolysaccharide enhance sensitivity to TNF-α-mediated cell death. Int Immunol 2:903-908.
46. Fulton AM, Chong YC 1992 The role of macrophage-derived TNFα in the induction of sublethal tumor cell DNA damage. Carcinogenesis 13:77-81.
47. Lewis M, Tartaglia LA, Lee A, Bennett GL, Rice GC, Wong GHW, Chen EY, Goeddel DV 1991 Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci USA 88:2830-2834.
48. Hirai H, Fujisawa J, Suzuki T, Ueda M, Muramatsu M, Tsuboi A, Arai N, Yoshida M 1992 Transcriptional activator tax of HTLV-I binds to the NF-κB precursor p105. Oncogene 7:1737-1742.
49. Wong GL, Luben RA, Cohn DV 1977 1, 25-Dihydroxycholecalciferol and parathormone: Effects on isolated osteoclast-like and osteoblast-like cells. Science 197:663-665.
50. Nakatani Y, Tsunoi M, Hakeda Y, Kurihara N, Fujita K, Kumegawa M 1984 Effects of parathyroid hormone on cAMP production and alkaline phosphatase activity in osteoblastic clone MC3T3-E1 cells. Biochem Biophys Res Commun 123: 894-898.
51. Kano J. Sugimoto T, Fukase M, Chihara K 1994 Direct involvement of cAMP dependent protein kinase in the regulation of alkaline phosphatase activity by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic UMR-106 cells. Biochem Biophys Res Commun 199:271-276.
52. Schütze S, Nottrott S, Pfizenmaier, Kronke M 1990 Tumor necrosis factor signal transduction. Cell-type-specific activation and translocation of protein kinase C. J Immunol 144:2604-2608.
53. Nishioka K, Maruyama I, Sato K. Kitajima I, Nakajima Y, Osame M 1989 Chronic inflammatory arthropathy associated with HTLV-I. Lancet i:441.
54. Iwakura Y, Tosu M, Yoshida E, Takiguchi M, Sato K. Kitajima I, Nishioka K, Yamamoto K, Takeda T, Hatanaka M 1991 Induction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-I. Science 253:1026-1028.