The skewed TCR-BV repertoire displayed at the maternal-fetal interface of women with unexplained pregnancy loss

American Journal of Reproductive Immunology

Volumn 54, Issue 2, 2005, Pages 84-95

  Wang, Xipeng ^a   Ma, Zhengwen ^b   Hong, Yan ^a   Zhao, Aimin ^a   Qiu, Lihua ^a   Lu, Peihua ^b   Lin, Qide ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Abortion; Complementarity determining region; Immunology; T cell receptor

Indexed keywords

T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; ARTICLE; CALCULATION; CHINA; COMPARATIVE STUDY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; DECIDUA; DISEASE PREDISPOSITION; FEMALE; FETUS WASTAGE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PLACENTA FUNCTION; PRIORITY JOURNAL; SEROPREVALENCE; SPECTROSCOPY; SPONTANEOUS ABORTION; UNIVERSITY HOSPITAL;

ABORTION, HABITUAL; ADULT; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; HUMANS; MIDDLE AGED; PREGNANCY; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 23144464151     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2005.00291.x     Document Type: Article

References (55)

1. Clark DA, Coulam CB, Daya S, Chaouat G: Unexplained sporadic and recurrent miscarriage in the new millennium: a critical analysis of immune mechanisms and treatments. Hum Reprod Update 2001; 7:501-511.
2. Coulam CB, Stephenson M, Stern JJ, Clark DA: Immunotherapy for recurrent pregnancy loss: analysis of results from clinical trials. Am J Reprod Immunol 1996; 35:352-359.
3. Cramer DW, Wise LA: The epidemiology of recurrent pregnancy loss. Semin Reprod Med 2000; 18:331-339.
4. Stephenson M: Frequence of factors associated with habitual abortion in 197 couples. Fertil Steril 1996; 66:24-29.
5. Pearson H: Reproductive immunology: immunity's pregnant pause. Nature 2002; 420:265.
6. Moffett A, Loke YW: The immunological paradox of pregnancy: a reappraisal. Placenta 2004; 25:1-8.
7. Mellor AL, Munn DH: Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression. Annu Rev Immunol 2000; 18:367-391.
8. Tafuri A, Alferink J, Moller P, Hammerling GJ, Arnold B: T cell awareness of paternal alloantigens during pregnancy. Science 1995; 270:630-633.
9. Porter TF, Scott JR: Alloimmune causes of recurrent pregnancy loss. Semin Reprod Med 2000; 18:393-400.
10. Pandey MK, Thakur S, Agrawal S: Lymphocyte immunotherapy and its probable mechanism in the maintenance of pregnancy in women with recurrent spontaneous abortion. Arch Gynecol Obstet 2004; 269:161-172.
11. Hill JA, Choi BC: Maternal immunological aspects of pregnancy success and failure. J Reprod Fertil Suppl 2000; 55:91-97.
12. Psarra K, Kapsimali V, Tarassi K, Dendrinos S, Athanasiadis T, Botsis D, Kreatsas G, Papasteriades C: TCRgammadelta + T lymphocytes in unexplained recurrent spontaneous abortions. Am J Reprod Immunol 2001; 45:6-11.
13. Lachapelle MH, Miron P, Hemmings R, Roy DC: Endometrial T, B, and NK cells in patients with recurrent spontaneous abortion. Altered profile and pregnancy outcome. J Immunol 1996; 156:4027-4034.
14. Garcia KC, Degano M, Stanfield RL, Brunmark A, Jackson MR, Peterson PA, Teyton L, Wilson IA: An alpha beta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 1996; 274:209-219.
15. Arstila TP, Casrouge A, Baron V, Even J, Kanellopoulos J, Kourilsky P: A direct estimate of the human alphabeta T cell receptor diversity. Science 1999; 286:958-961.
16. Nikolich-Zugich J, Slifka MK, Messaoudi I: The many important facets of T-cell repertoire diversity. Nat Rev Immunol 2004; 4:123-132.
17. Currier JR, Deulofeut H, Barron KS, Kehn PJ, Robinson MA: Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity. Hum Immunol 1996; 48:39-51.
18. Wu CJ, Chillemi A, Alyea EP, Orsini E, Neuberg D, Soiffer RJ, Ritz J: Reconstitution of T-cell receptor repertoire diversity following T-cell depleted allogeneic bone marrow transplantation is related to hematopoietic chimerism. Blood 2000; 95:352-359.
19. Coleman S, Perera P, Fisher J, Hoy T, Burnett AK, Lim SH: Abnormal TCR V beta repertoire in patients with chronic myeloid leukaemia. Br J Haematol 1995; 90:358-363.
20. Currier JR, Deulofeut H, Barron KS, Kehn PJ, Robinson MA: Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity. Hum Immunol 1996; 48:39-51.
21. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J: Interaction of Staphylococcus aureus toxin 'superantigens' with human T cells. Proc Natl Acad Sci U S A 1989; 86:8941-8945.
22. Chauhan B, Hutcheson PS, Slavin RG, Bellone CJ: T-cell receptor bias in patients with allergic bronchopulmonary aspergillosis. Hum Immunol 2002; 63:286-294.
23. Giovannetti A, Mazzetta F, Caprini E, Aiuti A, Marziali M, Pierdominici M, Cossarizza A, Chessa L, Scala E, Quinti I, Russo G, Fiorilli M: Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia. Blood 2002; 100:4082-4089.
24. Cancrini C, Romiti ML, Di Cesare S, Angelini F, Gigliotti D, Livadiotti S, Bertini E, Rossi P, Racioppi L: Restriction in T-cell receptor repertoire in a patient affected by trichothiodystrophy and CD4+ lymphopenia. Scand J Immunol 2002; 56:212-216.
25. Kock H, Risitano AM, Zeng W, Wlodarski M, Lottemann C, Nakamura R, Barrett J, Young NS, Maciejewski JP: Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens. Blood 2002; 99:3668-3675.
26. Rezvany MR, Jeddi-Tehrani M, Wigzell H, Osterborg A, Mellstedt H: Leukemia-associated monoclonal and oligoclonal TCR-BV use in patients with B-cell chronic lymphocytic leukemia. Blood 2003; 101:1063-1070.
27. Chen M, Xu XC, Wu WS, Mohanakumar T: Analysis of variable region of T-cell receptor beta chain usage in the human anti-porcine xenoresponse. Transplantation 1999; 68:586-589.
28. Girardi G, Salmon JB: The role of complement in pregnancy and fetal loss. Autoimmunity 2003; 36: 19-26.
29. Yamada H, Kato EH, Kobashi G, Ebina Y, Shimada S, Morikawa M, Sakuragi N, Fujimoto S: High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion. Am J Reprod Immunol 2001; 46:132-136.
30. Quack KC, Vassiliadou N, Pudney J, Anderson DJ, Hill JA: Leukocyte activation in the decidua of chromosomally normal and abnormal fetuses from women with recurrent abortion. Hum Reprod 2001; 16:949-955.
31. Yamada H, Kato EH, Morikawa M, Shimada S, Saito H, Watari M, Minakami H, Nishihira J: Decreased serum levels of macrophage migration inhibition factor in miscarriages with normal chromosome karyotype. Hum Reprod 2003; 18:616-620.
32. Tafuri A, Alferink J, Moller P, Hammerling GJ, Arnold B: T cell awareness of paternal alloantigens during pregnancy. Science 1995; 270:630-633.
33. Makrigiannakis A, Zoumakis E, Kalantaridou S, Coutifaris C, Margioris AN, Coukos G, Rice KC, Gravanis A, Chrousos GP: Corticotropin-releasing hormone promotes blastocyst implantation and early maternal tolerance. Nat Immunol 2001; 2:1018-1024.
34. Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, Brown C, Mellor AL: Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998; 281:1191-1193.
35. Sayegh MH, Akalin E, Hancock WW, Russell ME, Carpenter CB, Linsley PS, Turka LA: CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 1995; 181:1869-1874.
36. Lin H, Mosmann TR, Guilbert L, Tuntipopipat S, Wegmann T: Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J Immunol 1993; 151:4562-4573.
37. Wang X, Lin Q, Ma Z, Hong Y, Zhao A, Di W, Lu P: Association of the A/G polymorphism at position 49 in exon 1 of CTLA-4 with the susceptibility to unexplained recurrent spontaneous abortion in the Chinese population. Am J Reprod Immunol 2005; 53:100-105.
38. Hayakawa S, Karasaki-Suzuki M, Itoh T, Ishii M, Kanaeda T, Nagai N, Takahashi-Yamamota N, Tochigi M, Chishima F, Fujii TK, Oyama J, Kitanaka S, Satoh K: Effects of paternal lymphocyte immunization on peripheral Th1/Th2 balance and TCR V beta and V gamma repertoire usage of patients with recurrent spontaneous abortions. Am J Reprod Immunol 2000; 43:107-115.
39. Tsuda H, Sakai M, Michimata T, Tanebe K, Hayakawa S, Saito S: Characterization of NKT cells in human peripheral blood and decidual lymphocytes. Am J Reprod Immunol 2001; 45:295-302.
40. Ito K, Karasawa M, Kawano T, Akasaka T, Koseki H, Akutsu Y, Kondo E, Sekiya S, Sekikawa K, Harada M, Yamashita M, Nakayama T, Taniguchi M: Involvement of decidual Valpha14 NKT cells in abortion. Proc Natl Acad Sci U S A 2000; 97:740-744.
41. Crough T, Purdie DM, Okai M, Maksoud A, Nieda M, Nicol AJ: Modulation of human Valpha24(+)Vbeta11(+) NKT cells by age, malignancy and conventional anticancer therapies. Br J Cancer 2004; 91:1880-1886.
42. van der Vliet HJ, von Blomberg BM, Hazenberg MD, Nishi N, Otto SA, van Benthem BH, Prins M, Claessen FA, van den Eertwegh AJ, Giaccone G, Miedema F, Scheper RJ, Pinedo HM: Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection. J Immunol 2002; 168:1490-1495.
43. Shimada S, Iwabuchi K, Kato EH, Morikawa M, Sakuragi N, Onoe K, Minakami H, Yamada H: No difference in natural-killer-T cell population, but Th2/Tc2 predominance in peripheral blood of recurrent aborters. Am J Reprod Immunol 2003; 50:334-339.
44. Shimada S, Kato EH, Morikawa M, Iwabuchi K, Nishida R, Kishi R, Onoe K, Minakami H, Yamada H: No difference in natural killer or natural killer T-cell population, but aberrant T-helper cell population in the endometrium of women with repeated miscarriage. Hum Reprod 2004; 19:1018-1024.
45. Huang SK, Yi M, Palmer E, Marsh DG: A dominant T cell receptor beta-chain in response to a short ragweed allergen, Amb a 5. J Immunol 1995; 154:6157-6162.
46. Kotzin BL, Karuturi S, Chou YK, Lafferty J, Forrester JM, Better M, Nedwin GE, Offner H, Vandenbark AA: Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis. Proc Natl Acad Sci U S A 1991; 88:9161-9165.
47. Vandenbark AA, Chou YK, Whitham R, Mass M, Buenafe A, Liefeld D, Kavanagh D, Cooper S, Hashim GA, Offner H: Treatment of multiple sclerosis with T-cell receptor peptides: results of a double-blind pilot trial. Nat Med 1996; 2:1109-1115.
48. Bourdette DN, Whitham RH, Chou YK, Morrison WJ, Atherton J, Kenny C, Liefeld D, Hashim GA, Offner H, Vandenbark AA: Immunity to TCR peptides in multiple sclerosis: I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides. J Immunol 1994; 152:2510-2519.
49. Gran B, Gestri D, Sottini A, Quiros Roldan E, Bettinardi A, Signorini S, Primi D, Ballerini C, Taiuti R, Amaducci L, Massacesi L: Detection of skewed T-cell receptor V-beta gene usage in the peripheral blood of patients with multiple sclerosis. J Neuroimmunol 1998; 85:22-32.
50. Hayakawa S, Saito S, Nemoto N, Chishima F, Akiyama K, Shiraishi H, Hayakawa J, Karasaki-Suzuki M, Fujii KT, Ichijo M: Expression of recombinase-activating genes (RAG-1 and 2) in human decidual mononuclear cells. J Immunol 1994; 153:4934-4939.
51. Mincheva-Nilsson L, Kling M, Hammarstrom S, Nagaeva O, Sundqvist KG, Hammarstrom ML, Baranov V: Gamma delta T cells of human early pregnancy decidua: evidence for local proliferation, phenotypic heterogeneity, and extrathymic differentiation. J Immunol 1997; 159:3266-3277.
52. Yamasaki M, Sasho T, Moriya H, Kanno M, Harada M, Kamada N, Shimizu E, Nakayama T, Taniguchi M: Extrathymic development of V{{alpha}}11 T cells in placenta during pregnancy and their possible physiological role. J Immunol 2001; 166:7244-7249.
53. Silins SL, Cross SM, Krauer KG, Moss DJ, Schmidt CW, Misko IS: A functional link for major TCR expansions in healthy adults caused by persistent Epstein-Barr virus infection. J Clin Invest 1998; 102: 1551-1558.
54. Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, Edghill-Smith Y, Kuroda MJ, Bogdan D, Kuntsman K: T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 2004; 21:793-803.
55. Liu X, Chesnokova V, Forman SJ, Diamond DJ: Molecular analysis of T-cell receptor repertoire in bone marrow transplant recipients: evidence for oligoclonal T-cell expansion in graft-versus-host disease lesions. Blood 1996; 87:3032-3044.