Endometrial T, B, and NK cells in patients with recurrent spontaneous abortion: Altered profile and pregnancy outcome

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 4027-4034

  Lachapelle, Marie Hélène ^a   Miron, Pierre ^a   Hemmings, Robert ^a   Roy, Denis Claude ^a,b  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b Inst Med de la Repro de Montreal   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD20 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIUM CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPHENOTYPING; IMMUNOREGULATION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROGNOSIS; SPONTANEOUS ABORTION; SUPPRESSOR CELL;

ABORTION, HABITUAL; ADULT; B-LYMPHOCYTES; ENDOMETRIUM; FEMALE; HUMANS; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; PREGNANCY; PREGNANCY OUTCOME; T-LYMPHOCYTES;

EID: 0029870464     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Coulam, C. B., and D. A. Clark 1991. Report from the ethics committee for immunotherapy, American Society for the Immunology of Reproduction. Am. J. Reprod. Immunol. 26:93.
2. Diedrich, U., I. Hansmann, D Janke, O. Opitz, and H. D. Probeck. 1983. Chromosome anomalies in 136 couples with a history of recurrent abortions. Hum. Genet. 65:48.
3. Hill, J. A , and V. A. Raviniker. 1990. Recurrent abortion In Gynecology: Principles and Practice. K J. Ryan, ed Year Book, New York, p 406.
4. Stray-Pederson, B., and S. Stray-Pederson. 1984. Etiologic factors and subsequent reproductive performance in 195 couples with a prior history of habitual abortion Am. J. Obstet. Gynecol. 148.140.
5. Hill, J. A., F. Haimovici, and D. J Anderson. 1987. Products of activated lymphocytes and macrophages inhibit mouse embryo development in vitro. J. Immunol 139:2250
6. Carp, H. J. A., V. Toder, E. Gazit, S. Orgad, S. Mashiach, D. M. Serr, and L. Nebel 1988. Paternal leucocyte immunization and habitual abortion Contemp. Rev. Obstet. Gynaecol. 1:49.
7. Hill, J. A., K. Polgar, B. L Harlow, and D. J. Anderson. 1992. Evidence of embryo- and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion. Am. J. Obstet. Gynecol 166.1044.
8. Stern, J. J., and C. B Coulam. 1993 Current status of immunologic recurrent pregnancy loss. Curr Opin. Obstet Gynecol. 5:252.
9. Bulmer, J. N. 1989. Decidual cellular responses. Curr. Opin. Immunol. 1.1141.
10. Yokoyama, M., M. Sano, K. Sonoda, M. Nozaki, G I Nakamura, and H. Nakano. 1994. Cytotoxic cells directed against placental cells detected in human habitual abortions by an in vitro terminal labeling assay Am. J. Reprod. Immunol. 31:197.
11. Gendron, R. L., and M. G. Baines. 1988 Infiltrating decidual natural killer cells are associated with spontaneous abortion in mice. Cell. Immunol 113:261.
12. Duclos, A. J., E. K. Haddad, and M. G. Baines. 1995. Presence of activated macrophages in a murine model of early embryo loss. Am. J Reprod Immunol. 33:354
13. Crepeau, M. A., and B. A. Croy. 1988. Evidence that specific cellular immunity cannot account for death of Mus caroli embryos transferred to Mus musculus with severe combined deficiency disease. Transplantation 45.1104.
14. + murine uterine suppressor cells persist after implantation and may reduce the spontaneous abortion rate in CBA/J mice. Cell. Immunol. 123-334.
15. Clark, D. A. 1994. Maternal aggression against placenta? Am. J. Reprod. Immunol. 31.205.
16. Baines, M. G., and R. L. Gendron. 1990. Are both endogenous and exogenous factors involved in spontaneous foetal abortion? Res. Immunol. 141:154.
17. Yamada, H., K. Polgar, and J. A. Hill. 1994. Cell-mediated immunity to trophoblast antigens in women with recurrent spontaneous abortion. Am. J. Obstet. Gynecol 170.1339.
18. Lachapelle, M. H., P. Miron, R. Hemmings, C Baron, and D C. Roy. 1996. Flow-cytometric characterization of hematopoietic cells in non-pregnant human endometrium. Am. J. Reprod. Immunol. 35:5
19. + lymphoid cells in human first trimester pregnancy decidua as a source of novel transforming growth factor-β2-related imimmosuppresstve factors. Hum. Reprod. 9:2270.
20. bright natural killer cells. Cell. Immunol. 152:605
21. Starkey, P. M., I. L. Sargent, and C. W G. Redman. 1988. Cell populations in human early pregnancy decidua: characterization and isolation of large granular lymphocytes by flow cytometry. Immunology 65.129.
22. Maruyama, T., T. Makino, T. Sugi, H. Matsubayashi, N. Ozawa, and S. Nozawa. 1992. Flow-cytometric analysis of immune cell populations in human decidua from various types of first-trimester pregnancy Hum. Immunol 34:212
23. King, A., V. Wellings, L. Gardner, and Y W. Loke. 1989. Immunocytochemical characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle Hum. Immunol. 24:195.
24. Kamat, B. R , and P. G. Isaacson. 1987. The immunocytochemical distribution of leukocytic subpopulations in human endometrium. Am. J. Pathol. 127.66.
25. Bulmer, J N , P. M. Johnson, and D. Bulmer. 1987. Leucocyte populations in human decidua and endometrium. In Immunoregulation and Fetal Survival T. J Gill, and T. G. Wegmann, eds. Oxford University Press, Oxford, U.K., p. 111.
26. Nagler, A , L. L Lanier, S. Cwirla, and J. H. Phillips. 1989. Comparative studies of human FCRIII-positive and negative natural killer cells. J. Immunol. 143:3183.
27. Robertson, M. J., and J. Ritz. 1990. Biology and clinical relevance of human natural killer cells. Blood 76:2421.
28. Johnson, P. M. 1993. Immunobiology of the human placental trophoblast. Exp. Clin Immunogenet. 10:118
29. Zigril, M., A Fein, H Carp, and V. Toder 1991. Immunopotentiation reverses the embryotoxic effect of serum from women with pregnancy loss. Fertil. Steril. 56:653
30. Daya, S., K L. Rosenthal, and D. A. Clark 1987. Immunosuppression factor(s) produced by decidua-associated suppressor cells: a proposed mechanism for fetal allograft survival. Am. J. Obstet Gynecol. 156:344.
31. Clark, D A , R. Slapsys, B. A. Croy, J. Kreek, and J. Rossant. 1984 Local active suppression by suppressor cells in the decidua: a review. Am. J. Reprod. Immunol 5:78.
32. Daya, S., D. A Clark, C. Devlin, J. Jarrell, and A. Chaput. 1985. Suppressor cells in human decidua Am. J. Obstet. Gynecol. 151:267.
33. Lin, H., T. R Mosmann, L. Gilbert, S. Tuntipopipot, and T. G. Wegman. 1993. Synthesis of Thelper 2-type cytokines at the maternal-fetal interface. J Immunol. 151.4562.
34. Hill, J. A , K. Polgar, and D. J Anderson. 1995- T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortton. JAMA 273.1933.
35. + T cell-dependent suppression of natural effector cell cytotoxicity against trophobiast target cells. Cell. Immunol. 154:143.
36. Clark, D. A. 1992. Controversies in reproductive immunology. Crit. Rev. Immunol. 11.215.
37. + cells can predict pregnancy outcome. Am. J. Reprod. Immunol. 33 40.
38. Makida, R., M Minami, M Takamizawa, T. Juji, T. Fujii, and M. Mizuno. 1991. Natural killer cell activity and immunotherapy for recurrent spontaneous abortion. Lancet 338:579.
39. Aoki, K., S. Kajiura, Y. Matsumoto, M. Ogasawara, S Okada, Y Yagami, and N. Gleicher 1995. Preconceptional natural-killer-cell activity as a predictor of miscarriage. Lancet 345:1340.
40. Ritson, A , and J N. Bulmer 1987. Endometrial granulocytes in human decidua react with a natural-killer (NK) cell marker. Immunology 62:329.
41. Saxo, S., H. Kanzaki, M. Yoshida, M. Tokushige, H. S. Wang, M. Kariya, N. Okamoto, Y. Kariya, A. Uchida, S. Kasakura, and T. Mori. 1990. Studies on T-lineage cells in human decidua of first trimester pregnancies. Am. J. Reprod. Immunol. 24:67.
42. Wegmann, T. G. 1988. Maternal T cells promote placental growth and prevents spontaneous abortion. Immunol. Lett 17:297.
43. bright natural killer cells in the human early pregnancy decidua Int. Immunol. 5:559.
44. Tangri, S., T G. Wegman, H. Lin, and R. Raghupathy. 1994. Maternal antiplacental reactivity in natural immunologically mediated fetal resorptions. J. Immunol. 152:4903.
45. Drake, B. L., and J. R. Head. 1989. Murine trophoblast cells can be killed by lymphokine activated killer (LAK) cells. J. Immunol. 143:9.
46. Zuckerman, F. A., and J. R. Head. 1988. Murine trophoblast resist cell mediated lysis. II. Resistance to natural cell mediated cytotoxicity. Cell. Immunol. 116:274.
47. Clark, D. A., R. G. Lea, T. Poder, S. Daya, D. Banwatt, and C. Harley. 1990 Cytokines determining the success and failure of pregnancy. Ann. N.Y. Acad. Sci. 626:524.
48. Lea, R. G., J. Underwood, K. C. Flanders, H. Hirte, D. Banwatt, S. Finotto, I. Ohno, S. Daya, C. Harley, M. Michel, J. F. Mowbray, and D. A. Clark. 1995. A subset of patients with recurrent spontaneous abortion is deficient in transforming growth factor β-2 producing "suppressor cells" in uterine tissue near the placental attachment site. Am. J Reprod. Immunol. 34:52.
49. Beer, A. E. 1988. Immunologic aspects of normal pregnancy and recurrent spontaneous abortion. Semin. Reprod. Endocrinol 6:163.
50. Unander, A. M., and A. Lindholm. 1986. Transfusions of leukocyte rich erythrocyte "concentrates": a successful treatment in selected cases of habitual abortion. Am. J. Obstet. Gynecol. 154:516.
51. Mowbray, J. F., J. L. Underwood, M. Michel, P B Forbes, and R. W. Beard. 1987 Immunization with paternal lymphocytes in women with recurrent miscarriage. Lancet 2:679.