Antidiabetic sulphonylureas activate mitochondrial permeability transition in rat skeletal muscle

British Journal of Pharmacology

Volumn 145, Issue 6, 2005, Pages 785-791

  Skalska, Jolanta ^a   Debska, Grazyna ^a,b   Kunz, Wolfram S ^b   Szewczyk, Adam ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Glibenclamide; Mitochondria; Mitochondrial permeability transition; Skeletal muscle; Sulphonylureas

Indexed keywords

ANTIDIABETIC AGENT; CYCLOSPORIN A; GLIBENCLAMIDE; GLIPIZIDE; GLISOXEPIDE; N [4 [2 [N' METHYL N' (2 PYRIDYL)UREIDO]ETHYL]PHENYLSULFONYL] N' (4 METHYLCYCLOHEXYL)UREA; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL ORGANELLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE;

ANIMALS; CALCIUM; CYCLOSPORINE; GLIPIZIDE; GLYBURIDE; HYPOGLYCEMIC AGENTS; MEMBRANE POTENTIALS; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL SWELLING; MUSCLE, SKELETAL; OXYGEN; PERMEABILITY; RATS; SULFONYLUREA COMPOUNDS;

EID: 23044475670     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706214     Document Type: Article

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