Inhibition of neovascularization by environmental agents

Cardiovascular Toxicology

Volumn 5, Issue 2, 2005, Pages 215-226

  Ivnitski Steele, Irena ^a   Walker, Mary K ^a,b  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Dioxin; Endothelial cell; Environmental tobacco smoke; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON; PYRAZINE DERIVATIVE; SCLEROPROTEIN;

ANGIOGENESIS; CELL PROLIFERATION; CIGARETTE SMOKING; CONTROLLED STUDY; ENDOTHELIUM CELL; ENVIRONMENTAL FACTOR; HEALTH HAZARD; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; RESEARCH; REVIEW; RISK ASSESSMENT; SMOKING; TOBACCO;

ANIMALS; ENVIRONMENTAL POLLUTANTS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; TETRACHLORODIBENZODIOXIN; TOBACCO SMOKE POLLUTION;

NICOTIANA TABACUM;

EID: 23044470736     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/CT:5:2:215     Document Type: Review

References (69)

1. Cleaver, O. and Melton, D.A. (2003). Endothelial signaling during development. Nat. Med. 9:661-668.
2. Ferrara, N. (2001). Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am. J. Physiol. Cell Physiol. 280:C1358-C1366.
3. Jain, R.K. (2003). Molecular regulation of vessel maturation. Nat. Med. 9:685-693.
4. Pugh, C.W. and Ratcliffe, P.J. (2003). Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9:677-684.
5. DeVito, M.J., Birnbaum, L.S., Farland, W.H., and Gasiewicz, T.A. (1995). Comparisons of estimated human body burdens of dioxin like chemicals and TCDD body burdens in experimentally exposed animals. Environ. Health Perspect. 103:820-831.
6. Kim, J.-S., Lim, H.-S., Cho, S.-I., Cheong, H.-K., and Lim, M.-K. (2003). Impact of Agent Orange exposure among Korean Vietnam veterans. Industrial Health 41:149-157.
7. Bertazzi, P.A., Bernucci, I., Brambilla, G., Consonni, D., and Pesatori, A.C. (1998). The Seveso studies on early and long-term effects of dioxin exposure: a review. Environ. Health Perspect. 106:625-633.
8. Bertazzi, P.A., Consonni, D., Bachetti, S., Rubagotti, M., Baccarelli, A., Zocchetti, C., et al. (2001). Health effects of dioxin exposure: a 20-year mortality study. Am. J. Epidemiol. 153:1031-1044.
9. Flesch-Janys, D., Berger, J., Gum, P., Manz, A., Nagel, S., Waltsgott, H., et al. (1995). Exposure to polychlorinated dioxins and furans (PCDD/F) and mortality in a cohort of workers from a herbicide-producing plant in Hamburg, Federal Republic of Germany. Am. J. Epidemiol. 142:1165-1175.
10. Vena, J., Boffetta, P., Becher, H., Benn, T., Bueno-de-Mesquita, H.B., Coggon, D., et al. (1998). Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers. Environ. Health Perspect. 106:645-653.
11. Swanson, H.I. and Bradfield, C.A. (1993). The AH-receptor: genetics, structure and function. Pharmacogenetics 3:213-230.
12. Gu, Y.Z., Hogenesch, J.B., and Bradfield, C.A. (2000). The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40:519-561.
13. Gillesby, B.E., Stanostefano, M., Porter, W., Safe, S., Wu, Z.F., and Zacharewski, T.R. (1997). Identification of a motif within the 5′ regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated suppression. Biochem. 36:6080-6089.
14. Safe, S., Wormke, M., and Samudio, I. (2000). Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. J. Mamm. Gld. Biol. Neop. 5:295-306.
15. Wisk, J.D. and Cooper, K.R. (1990). The stage specific toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in embryos of the Japanese medaka (Oryzias latipes). Environ. Toxicol. Chem. 9:1159-1169.
16. Spitsbergen, J.M., Walker, M.K., Olson, J.R., and Peterson, R.E. (1991). Pathologic alterations in early life stages of lake trout, Salvelinus namaycush, exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin as fertilized eggs. Aquat. Toxicol. 19:41-72.
17. Walker, M.K., Spitsbergen, J.M., Olson, J.R., and Peterson, R.E. (1991). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) toxicity during early life stage development of lake trout (Sal-velinus namaycush). Can. J. Fish. Aquat. Sci. 48:875-883.
18. Guiney, P.D., Walker, M.K., Spitsbergen, J.M., and Peterson, R.E. (2000). Edema formation in 2,3,7,8-tetrachlor-odibenzo-p-dioxin-exposed lake trout (Salvelinus namaycush): a function of altered vascular endothelial cell permeability and blood ultrafiltration. Toxicol. Appl. Pharmacol. 168:1-14.
19. Walker, M.K. and Peterson, R.E. (1991). Potencies of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls, relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin, for producing early life stage mortality in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 21:219-238.
20. Walker, M.K. and Peterson, R.E. (1994). Toxicity of 2,3,7,8- tetrachlorodibenzo-p-dioxin to brook trout (Salvelinus fontinalis) during early development. Environ. Toxicol. Chem. 13:817-820.
21. Henry, T.R., Spitsbergen, J.M., Hornung, M.W., Abnet, C.C., and Peterson, R.E. (1997). Early life stage toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish (Danio rerio). Toxicol. Appl. Pharmacol. 142:56-68.
22. Belair, C.D., Peterson, R.E., and Heideman, W. (2000). Disruption of erythropoiesis by dioxin in zebrafish. Dev. Dyn. 222:581-594.
23. Dong, W., Teraoka, H., Yamazaki, K., Tsukiyama, S., Imani, S., Imagawa, T., et al. (2002). 2,3,7,8-Tetrachlorodibenzo-p-dioxin toxicity in the zebrafish embryo: Local circulation failure in the dorsal midbrain is associated with increased apoptosis. Toxicol. Sci. 69:191-201.
24. Dong, W., Teraoka, H., Tsujimoto, Y., Stegeman, J.J., and Hiraga, T. (2004). Role of aryl hydrocarbon receptor in mesencephalic circulation failure and apoptosis in zebrafish embryos exposed to 2,3,7,8-tetrachlorodibenzo-p- dioxin. Toxicol. Sci. 77:109-116.
25. Hornung, M.W., Spitsbergen, J.M., and Peterson, R.E. (1999). 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters cardiovascular and craniofacial development and function in sac fry of rainbow trout (Oncorhynchus mykiss). Toxicol. Sci. 47:40-51.
26. Bello, S.M., Heideman, W., and Peterson, R.E. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits regression of the common cardinal vein in developing zebrafish. Toxicol. Sci. 78:258-266.
27. Isogai, S., Horiguchi, M., and Weinstein, B.M. (2001). The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev. Biol. 230:278-301.
28. Prasch, A.L., Teraoka, H., Carney, S.A., Dong, W., Hiraga, T., Stegeman, J.J., et al. (2003). Aryl hydrocarbon receptor 2 mediates 2,3,7,8- tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol. Sci. B:138-150.
29. Cantrell, S.M., Lutz, L.H., Tillitt, D.E., and Hannink, M. (1996). Embryo-toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): The embryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in medaka (Oryzias latipes). Toxicol. Appl. Pharmacol. 141:23-34.
30. Teraoka, H., Dong, W., Iwasa, H., Daiji, E., Ueno, N., Stegeman, J.J., et al. (2003). Induction of cytochrome P4501A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish. Biochem. Biophys. Res. Commun. 304:223-228.
31. Carney, S.A., Peterson, R.E., and Heideman, W. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin activation of the aryl hydrocarbon receptor/Aryl hydrocarbon receptor nuclear translocatorpathway causes developmental toxicity through a CYP1A-independent mechanism in zebrafish. Mol. Pharmacol. 66:512-521.
32. Andreasen, E.A., Spitsbergen, J.M., Tanguay, R.L., Stegeman, J.J., Heideman, W., and Peterson, R.E. (2002). Tissue-specific expression of AHR2, ARNT2 and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol. Sci. 68:403-419.
33. Cantrell, S.M., Joy-Schlezinger, J., Stegeman, J.J., Tillitt, D.E., and Hannink, M. (1998). Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity. Toxicol. Appl. Pharmacol. 148:24-34.
34. Guiney, P.D., Smolowitz, R.M., Peterson, R.E., and Stegeman, J.J. (1997). Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in vascular endothelium with toxicity in early life stages of lake trout. Toxicol. Appl. Pharmacol. 143:256-273.
35. Uno, S., Dalton, T.P., Senft, A.P., Shertzer, H.G., and Nebert, D.W. (2002). Cyp1a1 (-/-) knockout mice, which have a functional aromatic hydrocarbon receptor, are protected against dioxin, as well as benzo(a)pyrene, toxicity in specific tissues. Toxicol. Sci. Suppl. 66:21.
36. Smith, A.G., Clothier, B., Carthew, P., Childs, N.L., Sinclair, P.R., Nebert, D.W., et al. (2001). Protection of the cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 173:89-98.
37. Ivnitski, I., Elmaoued, R., and Walker, M.K. (2001). 2,3,7,8- Tetrachlorodibenzo-p-dioxin inhibition of coronary angiogenesis is preceded by a decrease in myocyte proliferation and an increase in cardiac apoptosis. Teratology 64:201-212.
38. Walker, M.K. and Catron, T.F. (2000). Characterization of cardiotoxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related chemicals during early chick embryo development. Toxicol. Appl. Pharmacol. 167:210-221.
39. Lee, Y.M., Jeong, C.H., Koo, S.Y., Son, M.J., Song, H.S., Bae, S.K., et al. (2001). Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Dev. Dyn. 220:175-186.
40. Ivnitski-Steele, I.D., Sanchez, A., and Walker, M.K. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin reduces myocardial hypoxia and vascular endothelial growth factor expression during chick embryo development. Birth Defects Res.: Clin. Mol. Teratol. 70:51-58.
41. 188. Nat. Med. 5:495-502.
42. Harris, B.S., O'Brien, T.X., and Gourdie, R.G. (2002). Coronary arteriogenesis and differentiation of periarterial Purkinje fibers in the chick heart: is there a link? Tex. Heart Inst. J. 29:262-270.
43. Viragh, S., Gittenberger-de Groot, A.C., Poelmann, R.E., and Kalman, F. (1993). Early development of quail heart epicardium and associated vascular and glandular structures. Anat. Embryol. 188:381-393.
44. Vrancken Peeters, M.P., Gittenberger-de Groot, A.C., Mentink, M.M., and Poelmann, R.E. (1999). Smooth muscle cells and fibroblasts of the coronary arteries derive from epithelial-mesenchymal transformation of the epicardium. Anat. Embryol. 199:367-378.
45. Kwee, L., Baldwin, H.S., Shen, H.M., Stewart, C.L., Buck, C., Buck, C.A., et al. (1995). Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 121:489-503.
46. Yang, J.T., Rayburn, H., and Hynes, R.O. (1995). Cell adhesion events mediated by alpha4 integrins are essential in placental and cardiac development. Development 121:549-560.
47. Crispino, J.D., Lodish, M.B., Thurberg, B.L., Litovsky, S.H., Collins, T., Molkentin, J.D., et al. (2001). Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 15:839-844.
48. Watt, A.J., Battle, M.A., Li, J., and Duncan, S.A. (2004). GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc. Natl. Acad. Sci. USA 101:12,573-12,578.
49. Lie-Venema, H., Gittenberger-de Groot, A.C., van Empel, L.J.P., Boot, M.J., Kerkdijk, H., de Kant, E., et al. (2003). Ets-1 and Ets-2 transcription factors are essential for normal coronary and myocardial development in chicken embryos. Circ. Res. 92:749-756.
50. Yue, X. and Tomanek, R.J. (1999). Stimulation of coronary vasculogenesis/angiogenesis by hypoxia in cultured embryonic hearts. Dev. Dyn. 216:28-36.
51. Ivnitski-Steele, I.D. and Walker, M.K. (2003). Vascular endothelial growth factor rescues 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibition of coronary vascular outgrowth. Birth Defects Res.: Clin. Mol. Teratol. 67:496-503.
52. Banai, S., Shweiki, D., Pinson, A., Chandra, M., Lazarovici, G., and Keshet, E. (1994). Upregulation of vascular endothe-lial growth factor expression induced by myocardial ischemia: implications for coronary angiogenesis. Cardiovasc. Res. 28:1176-1179.
53. Ivnitski-Steele, I.D., Chavez, M., Friggens, M., and Walker, M.K. (2005). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits coronary vasculogenesis, in part, by reduced endothelial cell responsiveness to angiogenic stimuli, including vascular endothelial growth factor-A. Birth Defects Res.: Clin. Mol. Teratol. (Epub May 6, 2005).
54. Annas, A., Granberg, A.L., and Brittebo, E.B. (2000). Differential response of cultured human umbilical vein and artery endothelial cells to Ah receptor agonist treatment: cyp-dependent activation of food and environmental mutagens. Toxicol. Appl. Pharmacol. 169:94-101.
55. Zhao, W., Parrish, A.R., and Ramos, K.S. (1998). Constitutive and inducible expression of cytochrome P4501A1 and P4501B1 in human vascular endothelial and smooth muscle cells. In Vitro Cell. Dev. Bio. 34:671-673.
56. Abe, M. and Sato, Y. (2001). cDNA microarray analysis of the gene expression profile of VEGF-activated human umbilical vein endothelial cells. Angiogen. 4:289-298.
57. Fernandez-Salguero, P.M., Pineau, T., Hilbert, D.M., McPhail, T., Lee, S.S., Kimura, S., et al. (1995). Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science 268:722-726.
58. Gerritsen, M.E., Soriano, R., Yang, S., Zlot, C., Ingle, G., Toy, K., et al. (2003). Branching out: a molecular fingerprint of endothelial differentiation into tube-like structures generated by Affymetrix oligonucleotide arrays. Microcirc. 10:63-81.
59. Schmidt, J.V., Huei-Ting, G., Reddy, J.K., Simon, M.C., and Bradfield, C.A. (1996). Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. USA 93:6731-6736.
60. Ma, L., Chow, J.Y., and Cho, C.H. (1999). Cigarette smoking delays ulcer healing: role of constitutive nitro oxide synthase in rat stomach. Am. J. Physiol. 276:G238-G248.
61. Volm, M., Koomagi, R., and Mattern, J. (1999). Angiogenesis and cigarette smoking in squamous cell lung carcinomas: an immunohistochemical study of 28 cases. Anticancer Res. 19:333-336.
62. Magers, T., Talbot, P., DiCarlantonio, G., Knoll, M., Demers, D., Tsai, I., and Hoodbhoy, T. (1995). Cigarette smoke inhalation affects the reproductive system of female hamsters. Reprod. Toxicol. 9:513-525.
63. Stillman, R.J., Rosenberg, M.J., and Sachs, B.P. (1996). Smoking and reproduction. Fertil. Steril. 46:545-566.
64. Martin, T.R. and Braken, M.B. (1986). Association of low birth weight with passive smoke exposure in pregnancy. Am. J. Epidemiol. 124:633-642.
65. West, D.C., Thompson, W.D., Sells, P.G., and Burbridge, M.F. (2001). Angiogenesis assays using chick chorioallantoic membrane. In Angiogenesis Protocols (Murray, J.C., ed), Humana Press, Totowa, NJ, pp. 107-129.
66. Melkonian, G., Le, C., Zheng, W., Talbot, P., and Martins-Green, M. (2000). Normal patterns of angiogenesis and extracellular matrix deposition in chick chorioallantoic membranes are disrupted by mainstream and sidestream cigarette smoke. Toxicol. Appl. Pharmacol. 163:26-37.
67. Melkonian, G., Cheung, L., Marr, R., Tong, C., and Talbot, P. (2002). Mainstream and sidestream cigarette smoke inhibit growth and angiogenesis in the day 5 chick chorioallantoic membrane. Tox. Sci. 68:237-248.
68. Ji, L., Melkonian, G., Riveles, K., and Talbot, P. (2002). Identification of pyridine compounds in cigarette smoke solution that inhibit growth of the chick chorioallantoic membrane. Tox. Sci. 69:217-225.
69. Melkonian, G., Eckelhoefer, H., Wu, M., Wang, Y., Tong, C., Riveles, K., and Talbot, P. (2003). Growth and angiogenesis are inhibited in vivo in developing tissues by pyrazine and its derivatives. Tox. Sci. 74:393-401.