Angiogenesis and cigarette smoking in squamous cell lung carcinomas: An immunohistochemical study of 28 cases

Anticancer Research

Volumn 19, Issue 1 A, 1999, Pages 333-336

  Volm, Manfred ^a   Koomägi, Reet ^a   Mattern, Jürgen ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Microvessel density; Smoking; Squamous cell lung carcinomas; Thrombospondin; Vascular endothelial growth factor

Indexed keywords

DOXORUBICIN; THROMBOSPONDIN; VASCULOTROPIN;

ADULT; ANGIOGENESIS; ARTICLE; CIGARETTE SMOKING; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG CARCINOMA; MALE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ENDOTHELIAL GROWTH FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; SMOKING; THROMBOSPONDINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0344507141     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Carmichael J, Mitchel JB, De Graff WG, Gamson AF, Gazdar AF, Johnson BE, Glatstein E and Minna JD: Chemosensitivity testing of human lung cancer cell lines using the MTT assay. Br J Cancer 57: 540-547, 1985.
2. Ruckdeschel JC, Carney DN, Oie HK, Russel EK and Gazdar AF: In vitro chemosensitivity of human lung cancer cell lines. Cancer Treat Rep 71: 697-704, 1987.
3. Volm M, Samsel B and Mattern J: Relationship between chemoresistance of lung tumours and cigarette smoking. Br J Cancer 62: 255-256, 1990.
4. Volm M, Mattern J and Samsel B: Overexpression of P-glycoprotein and glutathione S-transferase-π in resistant non-small cell lung carcinomas of smokers. Br J Cancer 64: 700-704, 1991.
5. Koomägi R, Mattern J and Volm, M: Up-regulation of resistance-related proteins in human lung tumors with poor vascularization. Carcinogenesis 16: 2129-2133, 1995.
6. Volm M, Koomägi R and Mattern J: Interrelationship between microvessel density, expression of VEGF and resistance to doxorubicin in non-small cell lung carcinoma. Anticancer Res 16: 213-218, 1996.
7. Gasparini G: Angiogenesis research up to 1996. A commentary on the state of art and suggestions for future studies (overview). Eur J Cancer 32A: 2379-2385, 1996.
8. Bussolino F, Albini A, Camussi G, Presta M, Viglietto G, Ziche M and Persico G: Role of soluble mediators in angiogenesis. Eur J Cancer 32A: 2401-2412, 1996.
9. Volm M, Koomägi R, Mattern J and Stammler G: Angiogenic growth factors and their receptors in non-small cell lung carcinomas and their relationships to drug response in vitro. Anticancer Res 17: 169-172, 1997.
10. World Health Organization: Histological typing of lung tumours. Tumori 6: 253-272, 1981.
11. Carr DT and Mountain CF: Staging lung cancer. In: Lung cancer. Chemical diagnosis and treatment. (Straus MJ, ed). New York, Grune and Stratton, 1977, pp.151-161.
12. Group for Sensitivity testing of Tumors (KSST): In vitro short-term test to determine the resistance of human tumors to chemotherapy. Cancer 48: 2127-2135, 1981.
13. Volm M, Mattern J, Stammler G, Royer-Pokora B, Schneider, S, Weirich A and Ludwig R: Expression of resistance-related proteins in nephroblastoma after chemotherapy. Int J Cancer 63: 193-197, 1995.
14. Boyle P: Cancer, cigarette smoking and premature death in Europe: a review including the Recommendations of European Cancer Experts Consensus Meeting, Helsinki, October 1996. Lung Cancer, 17, 1-60, 1997.
15. Jedrychowsky W, Becher H, Wahrendorf J, Basa-Cierpialek Z and Gomola K: Effect of tobacco smoking on various histological types of lung cancer. Cancer Res. Clin. Oncol 118, 276-282, 1992.
16. Thorgeirsson SS, Huber BE, Sorrell S, Fojo A, Pastan I and Gottesman MM: Expression of the multidrug-resistant gene in hepatocarcinogenesis and regenerating rat liver. Science 236, 112:-1122, 1987.
17. Fairchild CR, Ivy SP, Rushmore T, Lee G, Koo P, Goldshmith M, Myers CE, Faber E and Cowan KH: Cacinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas. Proc Natl Acad Sci USA 84: 7701-7705, 1987.
18. Solt D and Farber E: New principle for analysis of chemical carcinogenesis. Nature, 263, 701-703, 1976.
19. Volm M, Zerban H, Mattern J and Efferth TH: Overexpression of P-glycoprotein in rat hepatocellular carcinomas induced with Nitrosomorpholine. Carcinogenesis 11: 169-172, 1990.
20. Mattern J, Kallinowski F, Herfarth C and Volm M: Association of resistance-related protein expression with poor vascularization and low levels of oxygen in human rectal cancer. Int J Cancer 67: 20-23, 1996.