Differential response of cultured human umbilical vein and artery endothelial cells to Ah receptor agonist treatment: CYP-dependent activation of food and environmental mutagens

Toxicology and Applied Pharmacology

Volumn 169, Issue 1, 2000, Pages 94-101

  Annas, Anita ^a   Granberg, A Lizette ^b   Brittebo, Eva B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Blood vessel; CYP1A1; DMBA; Endothelium; EROD; Heterocyclic amine; Trp P 1

Indexed keywords

1 (1 PROPYNYL)PYRENE; 1 ETHYNYLPYRENE; 3 AMINO 1,4 DIMETHYL 5H PYRIDO[4,3 B]INDOLE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ALPHA NAPHTHOFLAVONE; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 ISOENZYME; DICOUMAROL; DIMETHYL SULFOXIDE; ELLIPTICINE; ENVIRONMENTAL MUTAGEN; ETHOXYRESORUFIN; ETHOXYRESORUFIN DEETHYLASE; MICONAZOLE; NARINGENIN; PHENACETIN O DEETHYLASE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; XENOBIOTIC AGENT;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DRUG EXPOSURE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; INCUBATION TIME; METABOLIC ACTIVATION; PROTEIN EXPRESSION; TARGET ORGAN; UMBILICAL ARTERY; UMBILICAL VEIN; XENOBIOTIC METABOLISM;

EID: 0034669047     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2000.9054     Document Type: Article

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