CpG oligonucleotides partially inhibit growth of Mycobacterium tuberculosis, but not Salmonella or Listeria, in human monocyte-derived macrophages

FEMS Immunology and Medical Microbiology

Volumn 45, Issue 2, 2005, Pages 303-310

  Wang, Jennifer P ^a,b   Hayashi, Tomoko ^a   Datta, Sandip K ^a   Kornbluth, Richard S ^a   Raz, Eyal ^a   Guiney, Donald G ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

CpG; Macrophages; Tuberculosis

Indexed keywords

GAMMA INTERFERON; OLIGODEOXYNUCLEOTIDE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CONTROLLED STUDY; CPG ISLAND; DNA SEQUENCE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; MACROPHAGE; MONOCYTE; MOUSE; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SALMONELLA DUBLIN; SENSITIVITY AND SPECIFICITY; SEROTYPE; SPECIES COMPARISON;

ANIMALS; ANTITUBERCULAR AGENTS; BASE SEQUENCE; HUMANS; IMMUNITY, NATURAL; INTERFERON-GAMMA, RECOMBINANT; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; OLIGODEOXYRIBONUCLEOTIDES; SALMONELLA ENTERICA; SPECIES SPECIFICITY; VIRULENCE;

EID: 22844441756     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsim.2005.05.007     Document Type: Article

References (31)

1. J.L. Flynn, and J. Chan Immunology of tuberculosis Annu. Rev. Immunol. 19 2001 93 129
2. L.M. Sly, M. Lopez, W.M. Nauseef, and N.E. Reiner 1alpha,25- Dihydroxyvitamin D3-induced monocyte antimycobacterial activity is regulated by phosphatidylinositol 3-kinase and mediated by the NADPH-dependent phagocyte oxidase J. Biol. Chem. 276 2001 35482 35493
3. S. Thoma-Uszynski, S. Stenger, O. Takeuchi, M.T. Ochoa, M. Engele, P.A. Sieling, P.F. Barnes, M. Rollinghoff, P.L. Bolcskei, M. Wagner, S. Akira, M.V. Norgard, J.T. Belisle, P.J. Godowski, B.R. Bloom, and R.L. Modlin Induction of direct antimicrobial activity through mammalian toll-like receptors Science 291 2001 1544 1547
4. H. Wagner, H. Hacker, and G.B. Lipford Immunostimulatory DNA sequences help to eradicate intracellular pathogens Springer Semin. Immunopathol. 22 2000 147 152
5. T. Tokunaga, H. Yamamoto, S. Shimada, H. Abe, T. Fukuda, Y. Fujisawa, Y. Furutani, O. Yano, T. Kataoka, and T. Sudo Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity J. Natl. Cancer Inst. 72 1984 955 962
6. A.M. Krieg, A.K. Yi, S. Matson, T.J. Waldschmidt, G.A. Bishop, R. Teasdale, G.A. Koretzky, and D.M. Klinman CpG motifs in bacterial DNA trigger direct B-cell activation Nature 374 1995 546 549
7. A.M. Krieg, L. Love-Homan, A.K. Yi, and J.T. Harty CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge J. Immunol. 161 1998 2428 2434
8. S. Ito, K.J. Ishii, M. Gursel, H. Shirotra, A. Ihata, and D.M. Klinman CpG oligodeoxynucleotides enhance neonatal resistance to Listeria infection J. Immunol. 174 2005 777 782
9. S. Ito, K.J. Ishii, H. Shirota, and D.M. Klinman CpG oligodeoxynucleotides improve the survival of pregnant and fetal mice following Listeria monocytogenes infection Infect. Immun. 72 2004 3543 3548
10. S. Zimmermann, O. Egeter, S. Hausmann, G.B. Lipford, M. Rocken, H. Wagner, and K. Heeg CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis J. Immunol. 160 1998 3627 3630
11. K.L. Elkins, T.R. Rhinehart-Jones, S. Stibitz, J.S. Conover, and D.M. Klinman Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria J. Immunol. 162 1999 2291 2298
12. T. Hayashi, S.P. Rao, K. Takabayashi, J.H. Van Uden, R.S. Kornbluth, S.M. Baird, M.W. Taylor, D.A. Carson, A. Catanzaro, and E. Raz Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase Infect. Immun. 69 2001 6156 6164
13. B.L. Freidag, G.B. Melton, F. Collins, D.M. Klinman, A. Cheever, L. Stobie, W. Suen, and R.A. Seder CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium bovis BCG vaccination in mice challenged with M. tuberculosis Infect Immun. 68 2000 2948 2953
14. N.P. Juffermans, J.C. Leemans, S. Florquin, A. Verbon, A.H. Kolk, P. Speelman, S.J. van Deventer, and T. van der Poll CpG oligodeoxynucleotides enhance host defense during murine tuberculosis Infect. Immun. 70 2002 147 152
15. A.M. Cooper, D.K. Dalton, T.A. Stewart, J.P. Griffin, D.G. Russell, and I.M. Orme Disseminated tuberculosis in interferon gamma gene-disrupted mice J. Exp. Med. 178 1993 2243 2247
16. J.L. Flynn, J. Chan, K.J. Triebold, D.K. Dalton, T.A. Stewart, and B.R. Bloom An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection J. Exp. Med. 178 1993 2249 2254
17. M.G. Bonecini-Almeida, S. Chitale, I. Boutsikakis, J. Geng, H. Doo, S. He, and J.L. Ho Induction of in vitro human macrophage anti-Mycobacterium tuberculosis activity: requirement for IFN-gamma and primed lymphocytes J. Immunol. 160 1998 4490 4499
18. G. Auricchio, S.K. Garg, A. Martino, E. Volpe, A. Ciaramella, P. De Vito, P.M. Baldini, V. Colizzi, and M. Fraziano Role of macrophage phospholipase D in natural and CpG-induced antimycobacterial activity Cell. Microbiol. 5 2003 913 920
19. M. Hirschfeld, Y. Ma, J.H. Weis, S.N. Vogel, and J.J. Weis Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2 J. Immunol. 165 2000 618 622
20. B. Freundlich, and N. Avdalovic Use of gelatin/plasma coated flasks for isolating human peripheral blood monocytes J. Immunol. Methods 62 1983 31 37
21. W.R. Jacobs Jr., G.V. Kalpana, J.D. Cirillo, L. Pascopella, S.B. Snapper, R.A. Udani, W. Jones, R.G. Barletta, and B.R. Bloom Genetic systems for mycobacteria Methods Enzymol. 204 1991 537 555
22. D.E. Macfarlane, and L. Manzel Immunostimulatory CpG- oligodeoxynucleotides induce a factor that inhibits macrophage adhesion J. Lab. Clin. Med. 134 1999 501 509
23. G.S. Douvas, D.L. Looker, A.E. Vatter, and A.J. Crowle Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria Infect. Immun. 50 1985 1 8
24. T.F. Byrd Tumor necrosis factor alpha (TNFalpha) promotes growth of virulent Mycobacterium tuberculosis in human monocytes iron-mediated growth suppression is correlated with decreased release of TNFalpha from iron-treated infected monocytes J. Clin. Invest. 99 1997 2518 2529
25. F. Takeshita, and D.M. Klinman CpG ODN-mediated regulation of IL-12 p40 transcription Eur. J. Immunol. 30 2000 1967 1976
26. S. Bauer, C.J. Kirschning, H. Hacker, V. Redecke, S. Hausmann, S. Akira, H. Wagner, and G.B. Lipford Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition Proc. Natl. Acad. Sci. USA 98 2001 9237 9242
27. L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 2001 732 738
28. L.E. Bermudez Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide Clin. Exp. Immunol. 91 1993 277 281
29. B. Scorneaux, Y. Ouadrhiri, G. Anzalone, and P.M. Tulkens Effect of recombinant human gamma interferon on intracellular activities of antibiotics against Listeria monocytogenes in the human macrophage cell line THP-1 Antimicrob. Agents Chemother. 40 1996 1225 1230
30. H. Weighardt, C. Feterowski, M. Veit, M. Rump, H. Wagner, and B. Holzmann Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response J. Immunol. 165 2000 4537 4543
31. A.M. Cooper, J. Magram, J. Ferrante, and I.M. Orme Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis J. Exp. Med. 186 1997 39 45