Immunostimulatory CpG-oligodeoxynucleotides induce a factor that inhibits macrophage adhesion

Journal of Laboratory and Clinical Medicine

Volumn 134, Issue 5, 1999, Pages 501-509

  Macfarlane, Donald E ^a   Manzel, Lori ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033230842     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(99)90172-5     Document Type: Article

References (24)

1. 1. Krieg AM. Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA. Trends Microbiol 1996;4:73-6.
2. 2. Pisetsky DS. Immune activation by bacterial DNA: a new genetic code. Immunity 1996;5:303-10.
3. 3. Ballas ZK, Rasmussen WL, Krieg AM. Induction of NK activity and murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol 1996;157:1840-5.
4. 4. Klinman DM, Yi A-K, Beaucage SL, Conover J, Krieg AM. CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and INF-gamma. Proc Natl Acad Sci USA 1996;93:2879-83.
5. 5. Yi A-K, Hornbeck P, Lafrenz D, Drieg AM. CpG DNA rescue of murine B lymphoma cells from anti-IgM induced growth arrest and programmed cell death is associated with expression of c-myc, c-myb, myn, an bcI-2. J Immunol 1996;157:4918-25.
6. 6. Kreig AM, Yi A-K, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. CpG motifs in bacertial DNA trigger direct B cell activation. Nature 1995;374:546-9.
7. 7. Kreig AM, Matson S, Fischer E. Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs. Antisense Nucleic Acid Drug Dev 1996;6:133-9.
8. 8. Macfarlane DE, Manzel L, Krieg AM. Unmethylated CpG-containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B-lymphocytes induced by several agents: evidence for blockade at a distal signaling step. Immunology 1997;91: 586-93.
9. 9. Chu RS, Targoni OS, Drieg AM, Lehmann PV, Harding CV. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J Exp Med 1997;186:1623-31.
10. 10. Chace JH, Hooker NA, Midenstein KL, Krieg AM, Cowdery JS. Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12. Clin Immunol Immunopathol 1997;84:185-93.
11. 11. Macfarlane DE, Manzel L. Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine and structurally related compounds. J Immunol 1998;160: 1122-33.
12. 12. Davies DE, Lloyd JB. Monocyte-to-macrophage transition in vitro. A systematic study using human cells isolated by fractionation on Percoll. J Immunol Methods 1989;118: 9-16.
13. 13. Gordon S, Clarke S, Greaves D, Doyle A. Molecular immunobiology of macrophages: recent progress. Curr Opin Immunol 1995;7:24-33.
14. 14. Zuckerman SH, Ackerman SK, Douglas SD. Long-term human peripheral blood monocyte culters: establishment, metabolism and morphology of primary human monocyte-macrophage cell cultures. Immunology 1979;38:401-11.
15. 15. Lutz MB, Girolomoni G, Ricciardi-Castagnoli P. The role of cytokines in funcional regulation and differnetiation of dendritic cells [review]. Immunobiology 1996;195:431-55.
16. 16. Young DA, Lowe LD, Clark SC. Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibody-dependent cellular cytotoxicity. J Immunology 1990;145:607-15.
17. 17. Brugger W, Reinhardt D, Galanos C, Andreesen R. Inhibition of in vitro differentiation of human monocytes by lipopolysaccharides (LPS): phenotypic and functional analysis. Int Immunol 1991;3:221-7.
18. 18. Uguccioni M, D'Apuszzo M, Loetscher M, Dewald B, Baggiolini M. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. Eur J Immunol 1995;25:64-8.
19. 19. Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, et al. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J Exp Med 1997;185:1595-604.
20. 20. Tracy PB, Allen DH, Worfolk LA, Lawler RR. Monocyte/ macrophage regulation of coagulant events. Haemostasis 1996;26(suppl 1):6-11.
21. 21. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD 14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein [comments]. Science 1990; 249:1431-3.
22. 22. Pontow SE, Kery V, Stahl PD. Mannose receptor. Int Rev Cytol 1992;1376:221-44.
23. 23. Manzel L, Macfarlane DE. CpG-oligodeoxynucleotide supports growth of IL-6-dependent 7TD1 murine hybridoma cells. Life Sci 1997;62:23-27.
24. 24. Khaled Z, Benimetskaya L, Zeltser R, Khan T, Sharma HW, Narayanan R, et al. Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res 1996;24:737-45.