Membrane-associated zinc peptidase families: Comparing ACE and ACE2

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1751, Issue 1, 2005, Pages 2-8

  Guy, J L ^a   Lambert, D W ^a   Warner, F J ^a   Hooper, N M ^a   Turner, A J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Angiotensin; Coronavirus; Metallopeptidase; SARS; Structure

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; KALLIKREIN;

CONFERENCE PAPER; CORONAVIRUS; CRYSTAL STRUCTURE; CYTOLOGY; DROSOPHILA; ENDOTHELIUM CELL; ENZYME INHIBITION; HEART FUNCTION; KIDNEY FUNCTION; KIDNEY TUBULE EPITHELIUM; MEMBRANE TRANSPORT; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARS CORONAVIRUS; SEQUENCE HOMOLOGY; SURFACE PROPERTY;

AMINO ACID SEQUENCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BINDING SITES; CARBOXYPEPTIDASES; DROSOPHILA PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; METALLOENDOPEPTIDASES; PEPTIDYL-DIPEPTIDASE A; RECEPTORS, VIRUS; RENIN-ANGIOTENSIN SYSTEM; SARS VIRUS; SUBSTRATE SPECIFICITY;

CORONAVIRUS; MAMMALIA;

EID: 22744438257     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2004.10.010     Document Type: Conference Paper

References (38)

1. A.J. Turner, and N.M. Hooper The angiotensin-converting enzyme gene family: genomics and pharmacology Trends Pharmacol. Sci. 23 2002 177
2. D.J. Campbell Tissue renin-angiotensin system: sites of angiotensin formation J. Cardiovasc. Pharmacol. 10 1987 S1 S8
3. L.T. Skeggs, J.R. Kahn, and N.P. Shumway The preparation and function of the hypertensin-converting enzyme J. Exp. Biol. 103 1956 295 299
4. H.Y.T. Yang, E.G. Erdos, and Y. Levin A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin Biochim. Biophys. Acta 214 1970 374 376
5. S.R. Tipnis, N.M. Hooper, R. Hyde, E. Karran, G. Christie, and A.J. Turner A human homologue of angiotensin-converting enzyme J. Biol. Chem. 275 2000 33238
6. M. Donoghue, F. Hsieh, E. Baronas, K. Godbout, M. Gosselin, N. Stagliano, M. Donovan, B. Woolf, K. Robison, R. Jeyaseelan, R.E. Breitbart, and S. Acton A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 Circ. Res. 87 2000 e1
7. H. Zhang, J. Wada, K. Hida, Y. Tsuchiyama, K. Hiragushi, K. Shikata, H. Wang, S. Lin, Y.S. Kanwar, and H. Makino Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homologue of ACE2 and is developmentally regulated in embryonic kidneys J. Biol. Chem. 276 2001 17132
8. D. Harmer, M. Gilbert, R. Borman, and K.L. Clark Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme FEBS Lett. 532 2002 107
9. I. Hamming, W. Timens, M.L.C. Bulthuis, A.T. Lely, G.J. Navis, and H. van Goor Tissue distribution of ACE2 protein, the functional receptor for SARS cornavirus. A first step in understanding SARS pathogenesis J. Pathol. 203 2004 631
10. X. Houard, T.A. Williams, A. Michaud, P. Dani, R.E. Isaac, A.D. Shirras, D. Coates, P. Corvol, The Drosophila melanogaster-related angiotensin-I- converting enzymes Acer and Ance-distinct enzymic characteristics and alternative expression during pupal development 257 (1998) 599-606.
11. J.L. Guy, R.M. Jackson, K.R. Acharya, E.D. Sturrock, N.M. Hooper, and A.J. Turner Angiotensin-converting enzyme-2 (ACE2): comparative modelling of the active site, substrate specificity and chloride sensitivity Biochemistry 42 2003 13185
12. C. Vickers, P. Hales, V. Kaushik, L. Dick, J. Gavin, J. Tang, K. Godbout, T. Parsons, E. Baronas, F. Hsieh, S. Acton, M. Patane, A. Nichols, and P. Tummino Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase J. Biol. Chem. 277 2002 14838
13. L. Huang, D.J. Sexton, K. Skogerson, M. Devlin, R. Smith, I. Sanyal, T. Parry, R. Kent, J. Enright, Q. Wu, G. Conley, D. DeOliveira, L. Morganelli, M. Ducar, C.R. Wescott, and R.C. Ladner Novel peptide inhibitors of angiotensin-converting enzyme 2 J. Biol. Chem. 278 2003 15532
14. R. Natesh, S.L.U. Schwager, E.D. Sturrock, and K.R. Acharya Crystal structure of the human angiotensin-converting enzyme-lisinopril complex Nature 421 2003 551
15. H.M. Kim, D.R. Shin, O.J. Yoo, H. Lee, and J.O. Lee Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril FEBS Lett. 538 2003 65
16. K. Gordon, P. Redelinghuys, S.L.U. Schwager, M.R.W. Ehlers, A.C. Papageorgiou, R. Natesh, K.R. Acharya, and E.D. Sturrock Deglycosylation, processing and crystallisation of human testis angiotensin-converting enzyme Biochem. J. 371 2003 437
17. T.A. Williams, A. Michaud, X. Houard, M. Chauvet, and F. Soubrier Drosophila melanogaster angiotensin I-converting enzyme expressed in Pichia pastoris resembles the C domain of the mammalian homologue and does not require glycosylation for secretion and enzymic activity Biochem. J. 318 1996 125
18. P. Towler, B. Staker, S.G. Prasad, S. Menon, J. Tang, T. Parsons, D. Ryan, M. Fisher, D. Williams, N.A Dales, M.A. Patane, and M.W. Pantoliano ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis J. Biol. Chem. 279 2004 17996
19. N.A. Dales, A.E. Gould, J.A. Brown, E.F. Calderwood, B. Guan, C.A. Minor, J.M. Gavin, P. Hales, V.K. Kaushik, M. Stewart, P.J. Tummino, C.S. Vickers, T.D. Ocain, and M.A. Patane Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors J. Am. Chem. Soc. 124 2002 11852
20. 1098 is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity J. Biol. Chem. 36 2001 33518
21. H.S. Cheung, F.L. Wang, M.A. Ondetti, E.F. Sabo, and D.W. Cushman Binding of peptide substrates and inhibitors of angiotensin-converting enzyme J. Biol. Chem. 255 1980 401
22. M. Donoghue, H. Wakimoto, C.T. Maguire, S. Acton, P. Hales, N. Stagliano, V. Fairchild-Huntress, J. Xu, J.N. Lorenz, V. Kadambi, C.I. Berul, and R.E. Breitbart Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with down-regulated connexins J. Mol. Cell. Cardiol. 35 2003 1043
23. W. Li, M.J. Moore, N. Vasilieva, J. Sui, S.K. Wong, M.A. Berne, M. Somasundaran, J.L. Sullivan, K. Luzuriaga, T.C. Greenough, H. Choe, and M. Farzan Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Nature 426 2003 450
24. N. Li, J. Zimplemann, K. Cheng, J.A. Wilkins, and K.D. Burns The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules Am. J. Physiol., Renal Physiol. 2004 10.1152/ajprenal.00144. 2004 (Online prepublication)
25. G.C. Douglas, M.K. O'Brian, M.P. Hedger, D.K.L. Lee, M.A. Yarski, A.I. Smith, and R.A. Lew The novel angiotensin-converting enzyme (ACE) homologue, ACE2, is selectively expressed by adult leydig cells of the testis Endocrinology 145 2004 4703 4711
26. C. Tikellis, C.I. Johnston, J.M. Forbes, W.C. Burns, L.M. Burrell, J. Risvanis, and M.E. Cooper Characterisation of renal angiotensin-converting enzyme 2 in diabetic nephropathy Hypertension 41 2003 392
27. M.A. Crackower, R. Sarao, G.Y. Oudit, C. Yagil, I. Kozieradzki, S.E. Scanga, A.J. Oliveira-dos-Santos, J. da Costa, L. Zhang, Y. Pei, J. Scholey, C.M. Ferrario, A.S. Manoukian, M.C. Chappell, P.H. Backx, Y. Yagil, and J.M. Penninger Angiotensin-converting enzyme 2 is an essential regulator of heart function Nature 417 2002 822
28. A.J. Allred, M. Donoghue, S. Acton, and T.M. Coffman Regulation of blood pressure by the angiotensin converting enzyme homologue ACE2 Am. J. Nephrol. 13 2002 52A
29. M.A. Crackower, R. Sarao, C. Yagil, Y. Yagil, and J.M. Penninger ACE2-A novel candidate gene for hypertension Am. J. Hypertens. 14 2001 A78
30. A.A. Chen, G. Barnes, A. Foti, E. Nolin, S. Lewitzsky, J. Metivier, J. Meyer, A. Parker, and E. Topol Two single nucleotide polymorphisms in the ACE2 locus are associated with cardiovascular disease Genet. Epidemiol. 23 2002 272
31. M.C. Chappell, F. Jung, P.E. Gallagher, D.B. Averill, M.A. Crackower, J.M. Penninger, and C.M. Ferrario Omapatrilat treatment is associated with increased ACE2 and angiotensin (1-7) in spontaneously hypertensive rats Hypertension 40 2002 409
32. L.A. Neves, A.F. Williams, D.B. Averill, C.M. Ferrario, M.P. Walkup, and K.B. Brosnihan Pregnancy enhances the angiotensin (Ang)-(1-7) vasodilator response in mesenteric arteries and increases the renal concentration and urinary excretion of Ang-(1-7) Endocrinology 144 2003 3338
33. K.B. Brosnihan, L.A.A. Neves, J. Joyner, D.B. Averill, M.C. Chappell, R. Sarao, J. Penninger, and C.M. Ferrario Enhanced renal immunocytochemical expression of Ang-(1-7) and ACE2 during pregnancy Hypertension 42 2003 749
34. L.S. Zisman, R.S. Keller, B. Weaver, Q. Lin, R. Speth, M.R. Bristow, and C.C. Canver Increased angiotensin-(1-7)-forming activity in failing human heart ventricles. Evidence for up-regulation of the angiotensin-converting enzyme homologue ACE2 Circulation 108 2003 1707
35. L.S. Zisman, G.E. Meixell, M.R. Bristow, and C.C. Canver Angiotensin-(1-7) formation in the intact human heart. In vivo dependence on angiotensin II as substrate Circulation 108 2003 1679
36. M. Ye, J. Wysocki, P. Naaz, M.R. Salabat, M.S. LaPointe, and D. Batlle Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice. A renoprotective combination? Hypertension 43 2004 1120
37. R.E. Gilbert, H. Krum, J. Wilkinson-Berka, and D.J. Kelly The renin-angiotensin system and the long-term complications of diabetes: pathophysiological and therapeutic considerations Diabet. Med. 20 2003 607
38. T. Komatsu, Y. Suzuki, J. Imai, S. Sugano, M. Hida, A. Tanigami, S. Muroi, Y. Yamada, and K. Hanaoka Molecular cloning, mRNA expression and chromosomal localisation of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2) DNA Sequence 13 2002 217