메뉴 건너뛰기




Volumn 90, Issue 7, 2005, Pages 871-874

Gain of function, loss of control - A molecular basis for chronic myeloproliferative disorders

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE 2; PROTEIN TYROSINE KINASE;

EID: 22544481483     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial
Times cited : (40)

References (36)
  • 1
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood 1951;6:372-5.
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 2
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003;348:1201-14.
    • (2003) N Engl J Med , vol.348 , pp. 1201-1214
    • Cools, J.1    DeAngelo, D.J.2    Gotlib, J.3    Stover, E.H.4    Legare, R.D.5    Cortes, J.6
  • 3
    • 22544482989 scopus 로고    scopus 로고
    • Targeting mutated tyrosine kinases and their signalling pathways in haematological malignancies
    • Chalandon YSchwaller J. Targeting mutated tyrosine kinases and their signalling pathways in haematological malignancies. Haematologica 2005;90:XXX.
    • (2005) Haematologica , vol.90
    • Chalandon, Y.1    Schwaller, J.2
  • 4
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 5
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-61.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 6
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-97.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 8
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome
    • Apr 28; [Epub ahead of print]
    • Steensma DP, Dewald GW, Lasho TL, Powell HL, McClure RF, Levine RL, et al. The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome. Blood 2005:Apr 28; [Epub ahead of print].
    • (2005) Blood
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3    Powell, H.L.4    McClure, R.F.5    Levine, R.L.6
  • 9
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in Polycythemia vera
    • Apr 29; [Epub ahead of print]
    • Zhao R, Xing S, Li Z, Fu X, Li Q, Krantz SB, et al. Identification of an acquired JAK2 mutation in Polycythemia vera. J Biol Chem 2005:Apr 29; [Epub ahead of print].
    • (2005) J Biol Chem
    • Zhao, R.1    Xing, S.2    Li, Z.3    Fu, X.4    Li, Q.5    Krantz, S.B.6
  • 10
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • May 26; [Epub ahead or print]
    • Jones AV, Kreil S, Zoi K, Waghorn K, Curtis C, Zhang L, et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 2005:May 26; [Epub ahead or print].
    • (2005) Blood
    • Jones, A.V.1    Kreil, S.2    Zoi, K.3    Waghorn, K.4    Curtis, C.5    Zhang, L.6
  • 12
    • 0038281343 scopus 로고    scopus 로고
    • Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin
    • Liu E, Jelinek J, Pastore YD, Guan Y, Prchal JFPrchal JT. Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin. Blood 2003;101:3294-301.
    • (2003) Blood , vol.101 , pp. 3294-3301
    • Liu, E.1    Jelinek, J.2    Pastore, Y.D.3    Guan, Y.4    Prchal, J.F.5    Prchal, J.T.6
  • 13
    • 0031019581 scopus 로고    scopus 로고
    • Clonality analysis of hematopoiesis in essential thrombocythemia: Advantages of studying T lymphocytes and platelets
    • el-Kassar N, Hetet G, Briere JGrandchamp B. Clonality analysis of hematopoiesis in essential thrombocythemia: advantages of studying T lymphocytes and platelets. Blood 1997;89:128-34.
    • (1997) Blood , vol.89 , pp. 128-134
    • El-Kassar, N.1    Hetet, G.2    Briere, J.3    Grandchamp, B.4
  • 14
    • 0033555392 scopus 로고    scopus 로고
    • A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications
    • Harrison CN, Gale RE, Machin SJLinch DC. A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications. Blood 1999;93:417-24.
    • (1999) Blood , vol.93 , pp. 417-424
    • Harrison, C.N.1    Gale, R.E.2    Machin, S.J.3    Linch, D.C.4
  • 15
    • 0036720394 scopus 로고    scopus 로고
    • Predictive values of X-chromosome inactivation patterns and clinicohematologic parameters for vascular complications in female patients with essential thrombocythemia
    • Shih LY, Lin TL, Lai CL, Dunn P, Wu JH, Wang PN, et al. Predictive values of X-chromosome inactivation patterns and clinicohematologic parameters for vascular complications in female patients with essential thrombocythemia. Blood 2002;100:1596-601.
    • (2002) Blood , vol.100 , pp. 1596-1601
    • Shih, L.Y.1    Lin, T.L.2    Lai, C.L.3    Dunn, P.4    Wu, J.H.5    Wang, P.N.6
  • 16
    • 0016391236 scopus 로고
    • Letter: Bone-marrow responses in polycythemia vera
    • Prchal JFAxelrad AA. Letter: Bone-marrow responses in polycythemia vera. N Engl J Med 1974;290:1382.
    • (1974) N Engl J Med , vol.290 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 17
    • 0018917880 scopus 로고
    • Polycythaemia vera: In vitro studies of circulating erythroid progenitors
    • Lacombe C, Casadevall NVaret B. Polycythaemia vera: in vitro studies of circulating erythroid progenitors. Br J Haematol 1980;44:189-99.
    • (1980) Br J Haematol , vol.44 , pp. 189-199
    • Lacombe, C.1    Casadevall, N.2    Varet, B.3
  • 18
    • 0036108890 scopus 로고    scopus 로고
    • The predictive value of clonogenic stem cell assays for the diagnosis of polycythaemia vera
    • Zwicky C, Theiler L, Zbaren K, Ischi ETobler A. The predictive value of clonogenic stem cell assays for the diagnosis of polycythaemia vera. Br J Haematol 2002;117:598-604.
    • (2002) Br J Haematol , vol.117 , pp. 598-604
    • Zwicky, C.1    Theiler, L.2    Zbaren, K.3    Ischi, E.4    Tobler, A.5
  • 19
    • 0041940289 scopus 로고    scopus 로고
    • Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders
    • Kralovics R, Buser AS, Teo SS, Coers J, Tichelli A, van der Maas AP, et al. Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders. Blood 2003;102:1869-71.
    • (2003) Blood , vol.102 , pp. 1869-1871
    • Kralovics, R.1    Buser, A.S.2    Teo, S.S.3    Coers, J.4    Tichelli, A.5    Van Der Maas, A.P.6
  • 20
    • 6344262092 scopus 로고    scopus 로고
    • Serum erythropoietin concentration as a diagnostic tool for polycythemia vera
    • Cazzola M. Serum erythropoietin concentration as a diagnostic tool for polycythemia vera. Haematologica 2004;89:1159-60.
    • (2004) Haematologica , vol.89 , pp. 1159-1160
    • Cazzola, M.1
  • 21
    • 19644392085 scopus 로고    scopus 로고
    • Diagnostic value of serum erythropoietin level in patients with absolute erythrocytosis
    • Mossuz P, Girodon F, Donnard M, Latger-Cannard V, Dobo I, Boiret N, et al. Diagnostic value of serum erythropoietin level in patients with absolute erythrocytosis. Haematologica 2004;89:1194-8.
    • (2004) Haematologica , vol.89 , pp. 1194-1198
    • Mossuz, P.1    Girodon, F.2    Donnard, M.3    Latger-Cannard, V.4    Dobo, I.5    Boiret, N.6
  • 22
    • 0025975727 scopus 로고
    • Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3
    • Dai CH, Krantz SB, Means RT, Jr., Horn ST, Gilbert HS. Polycythemia vera blood burst-forming units-erythroid are hypersensitive to interleukin-3. J Clin Invest 1991;87:391-6.
    • (1991) J Clin Invest , vol.87 , pp. 391-396
    • Dai, C.H.1    Krantz, S.B.2    Means Jr., R.T.3    Horn, S.T.4    Gilbert, H.S.5
  • 23
    • 0026667283 scopus 로고
    • Polycythemia vera. II. Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor
    • Dai CH, Krantz SB, Dessypris EN, Means RT, Jr., Horn ST, Gilbert HS. Polycythemia vera. II. Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor. Blood 1992;80:891-9.
    • (1992) Blood , vol.80 , pp. 891-899
    • Dai, C.H.1    Krantz, S.B.2    Dessypris, E.N.3    Means Jr., R.T.4    Horn, S.T.5    Gilbert, H.S.6
  • 24
    • 0028045069 scopus 로고
    • Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: Studies in an improved serum-free medium
    • Correa PN, Eskinazi DAxelrad AA. Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium. Blood 1994;83:99-112.
    • (1994) Blood , vol.83 , pp. 99-112
    • Correa, P.N.1    Eskinazi, D.2    Axelrad, A.A.3
  • 25
    • 0034669997 scopus 로고    scopus 로고
    • Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia
    • Axelrad AA, Eskinazi D, Correa PNAmato D. Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia. Blood 2000;96:3310-21.
    • (2000) Blood , vol.96 , pp. 3310-3321
    • Axelrad, A.A.1    Eskinazi, D.2    Correa, P.N.3    Amato, D.4
  • 26
    • 0034210637 scopus 로고    scopus 로고
    • Translational pathophysiology: A novel molecular mechanism of human disease
    • Cazzola MSkoda RC. Translational pathophysiology: a novel molecular mechanism of human disease. Blood 2000;95:3280-8.
    • (2000) Blood , vol.95 , pp. 3280-3288
    • Cazzola, M.1    Skoda, R.C.2
  • 27
    • 0030811101 scopus 로고    scopus 로고
    • Hereditary hyperferritinemia-cataract syndrome: Relationship between phenotypes and specific mutations in the iron-responsive element of ferritin lignt-chain mRNA
    • Cazzola M, Bergamaschi G, Tonon L, Arbustini E, Grasso M, Vercesi E, et al. Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin lignt-chain mRNA. Blood 1997;90:814-21.
    • (1997) Blood , vol.90 , pp. 814-821
    • Cazzola, M.1    Bergamaschi, G.2    Tonon, L.3    Arbustini, E.4    Grasso, M.5    Vercesi, E.6
  • 28
    • 0031975482 scopus 로고    scopus 로고
    • An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia
    • Wiestner A, Schlemper RJ, van der Maas APSkoda RC. An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nat Genet 1998;18:49-52.
    • (1998) Nat Genet , vol.18 , pp. 49-52
    • Wiestner, A.1    Schlemper, R.J.2    Van Der Maas, A.P.3    Skoda, R.C.4
  • 29
    • 0036191941 scopus 로고    scopus 로고
    • Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera
    • Kralovics R, Guan YPrchal JT. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 2002;30:229-36.
    • (2002) Exp Hematol , vol.30 , pp. 229-236
    • Kralovics, R.1    Guan, Y.2    Prchal, J.T.3
  • 31
    • 0344845194 scopus 로고    scopus 로고
    • Pathways for mitotic homologous recombination in mammalian cells
    • Helleday T. Pathways for mitotic homologous recombination in mammalian cells. Mutat Res 2003;532:103-15.
    • (2003) Mutat Res , vol.532 , pp. 103-115
    • Helleday, T.1
  • 32
    • 12544257171 scopus 로고    scopus 로고
    • Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias
    • Raghavan M, Lillington DM, Skoulakis S, Debernardi S, Chaplin T, Foot NJ, et al. Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias. Cancer Res 2005;65:375-8.
    • (2005) Cancer Res , vol.65 , pp. 375-378
    • Raghavan, M.1    Lillington, D.M.2    Skoulakis, S.3    Debernardi, S.4    Chaplin, T.5    Foot, N.J.6
  • 33
    • 17444377587 scopus 로고    scopus 로고
    • JAKing up hematopoietic proliferation
    • Shannon KVan Etten RA. JAKing up hematopoietic proliferation. Cancer Cell 2005;7:291-3.
    • (2005) Cancer Cell , vol.7 , pp. 291-293
    • Shannon, K.1    Van Etten, R.A.2
  • 34
    • 19344362958 scopus 로고    scopus 로고
    • On the molecular origins of the chronic myeloproliferative disorders: It all makes sense
    • Kaushansky K. On the molecular origins of the chronic myeloproliferative disorders: it all makes sense. Blood 2005;105:4187-90.
    • (2005) Blood , vol.105 , pp. 4187-4190
    • Kaushansky, K.1
  • 35
  • 36
    • 18344393249 scopus 로고    scopus 로고
    • JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells
    • Zhao S, Zoller K, Masuko M, Rojnuckarin P, Yang XO, Parganas E, et al. JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells. Embo J 2002;21:2159-67.
    • (2002) Embo J , vol.21 , pp. 2159-2167
    • Zhao, S.1    Zoller, K.2    Masuko, M.3    Rojnuckarin, P.4    Yang, X.O.5    Parganas, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.