-
1
-
-
0031987277
-
Regulation of p53 downstream genes
-
El-Deiry WS. Regulation of p53 downstream genes. Semin Cancer Biol 1998; 8:345-57.
-
(1998)
Semin Cancer Biol
, vol.8
, pp. 345-357
-
-
El-Deiry, W.S.1
-
3
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991; 51:6304-11.
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
4
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53. Nat Genet 1992; 1:45-9.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
5
-
-
0026650531
-
A transcriptionally active DNA-binding site for human p53 protein complexes
-
Funk WD, Pak DT, Karas RH, Wright WE, Shay JW. A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol 1992; 12:2866-71.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 2866-2871
-
-
Funk, W.D.1
Pak, D.T.2
Karas, R.H.3
Wright, W.E.4
Shay, J.W.5
-
6
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculesue VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculesue, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
7
-
-
0034732258
-
Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
-
Takimoto R, El-Deiry WS. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 2000; 19:1735-53.
-
(2000)
Oncogene
, vol.19
, pp. 1735-1753
-
-
Takimoto, R.1
El-Deiry, W.S.2
-
8
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G, El-Deiry WS. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997; 17:141-3.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.D.8
Zhou, J.Y.9
Muschel, R.10
Hamilton, S.R.11
Spinner, N.B.12
Markowitz, S.13
Wu, G.14
El-Deiry, W.S.15
-
9
-
-
0001203366
-
Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
-
Wu GS, Burns TF, Zhan Y, Alnemri ES, El-Deiry WS. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res 1999; 59:2770-5.
-
(1999)
Cancer Res
, vol.59
, pp. 2770-2775
-
-
Wu, G.S.1
Burns, T.F.2
Zhan, Y.3
Alnemri, E.S.4
El-Deiry, W.S.5
-
10
-
-
0037171938
-
Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53
-
Mori T, Anazawa Y, Iiizumi M, Fukuda S, Nakamura Y, Arakawa H. Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53. Oncogene 2002; 21:2914-8.
-
(2002)
Oncogene
, vol.21
, pp. 2914-2918
-
-
Mori, T.1
Anazawa, Y.2
Iiizumi, M.3
Fukuda, S.4
Nakamura, Y.5
Arakawa, H.6
-
11
-
-
85047696901
-
A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1
-
Rozenfeld-Granot G, Krishnamurthy J, Kannan K, Toren A, Amariglio N, Givol D, Rechavi G. A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1. Oncogene 2002; 21:1469-76.
-
(2002)
Oncogene
, vol.21
, pp. 1469-1476
-
-
Rozenfeld-Granot, G.1
Krishnamurthy, J.2
Kannan, K.3
Toren, A.4
Amariglio, N.5
Givol, D.6
Rechavi, G.7
-
12
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev 1996; 10:1054-72.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
13
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-31.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
14
-
-
0033529121
-
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45
-
Zhan Q, Antinore MJ, Wang XW, Carrier F, Smith ML, Harris CC, Fornace AJ. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene 1999; 18:2892-900.
-
(1999)
Oncogene
, vol.18
, pp. 2892-2900
-
-
Zhan, Q.1
Antinore, M.J.2
Wang, X.W.3
Carrier, F.4
Smith, M.L.5
Harris, C.C.6
Fornace, A.J.7
-
15
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 27:293-9.
-
(1995)
Cell
, vol.27
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
16
-
-
0035265686
-
PUMA, a novel proapoptotic gene is induced by p53
-
Nakano K, Vousden KH. PUMA, a novel proapoptotic gene is induced by p53. Mol Cell 2001; 7:683-94.
-
(2001)
Mol Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
17
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 2001; 7:673-682.
-
(2001)
Mol Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
18
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden K, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002; 2:594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.1
Lu, X.2
-
20
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation-deficient p53
-
Haupt Y, Rowan S, Shaulian E, Vousden K, Oren M. Induction of apoptosis in HeLa cells by transactivation-deficient p53. Genes Dev 1995; 9:2170-83.
-
(1995)
Genes Dev
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, K.4
Oren, M.5
-
22
-
-
0028070989
-
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
Caelle C, Helmberg A, Karin M. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 1994; 370:220-3.
-
(1994)
Nature
, vol.370
, pp. 220-223
-
-
Caelle, C.1
Helmberg, A.2
Karin, M.3
-
23
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene mediated apoptosis
-
Attardi LD, Lowe SW, Brugarolas J, Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene mediated apoptosis. EMBO J 1996; 15:3693-701.
-
(1996)
EMBO J
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
24
-
-
0029143395
-
Essential role for p53-mediated transactivation in apoptosis but not growth suppression
-
Sabbatini P, Lin J, Levine AJ, White E. Essential role for p53-mediated transactivation in apoptosis but not growth suppression. Genes Dev 1995; 9:2184-92.
-
(1995)
Genes Dev
, vol.9
, pp. 2184-2192
-
-
Sabbatini, P.1
Lin, J.2
Levine, A.J.3
White, E.4
-
25
-
-
0026570140
-
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein
-
Charles CH, Abler AS, Lau LF. cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene 1992; 7:187-90.
-
(1992)
Oncogene
, vol.7
, pp. 187-190
-
-
Charles, C.H.1
Abler, A.S.2
Lau, L.F.3
-
26
-
-
0026779540
-
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
-
Keyse SM, Emslie EA. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 1992; 359:644-7.
-
(1992)
Nature
, vol.359
, pp. 644-647
-
-
Keyse, S.M.1
Emslie, E.A.2
-
27
-
-
0027261369
-
Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth
-
Noguchi T, Metz R, Chen L, Mattei MG, Carrasco D, Bravo R. Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth. Mol Cell Biol 1993; 13:5195-205.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5195-5205
-
-
Noguchi, T.1
Metz, R.2
Chen, L.3
Mattei, M.G.4
Carrasco, D.5
Bravo, R.6
-
28
-
-
0028955176
-
An emerging family of dual specificity MAP kinase phosphatases
-
Keyse SM. An emerging family of dual specificity MAP kinase phosphatases. Biochim Biophys Acta 1995; 1265:152-00.
-
(1995)
Biochim Biophys Acta
, vol.1265
, pp. 152-200
-
-
Keyse, S.M.1
-
29
-
-
0027358722
-
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
-
Sun H, Charles CH, Lau LF, Tonks NK. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993; 75:487-93.
-
(1993)
Cell
, vol.75
, pp. 487-493
-
-
Sun, H.1
Charles, C.H.2
Lau, L.F.3
Tonks, N.K.4
-
30
-
-
0030794511
-
Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
-
Franklin CC, Kraft AS. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 1997; 272:16917-23.
-
(1997)
J Biol Chem
, vol.272
, pp. 16917-16923
-
-
Franklin, C.C.1
Kraft, A.S.2
-
31
-
-
0035168692
-
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation
-
Li J, Gorospe M, Hutter D, Barnes J, Keyse SM, Liu Y. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. Mol Cell Biol 2001; 21:8213-24.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8213-8224
-
-
Li, J.1
Gorospe, M.2
Hutter, D.3
Barnes, J.4
Keyse, S.M.5
Liu, Y.6
-
32
-
-
0036829987
-
Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect
-
Xu Q, Konta T, Furusu A, Nakayama K, Lucio-Cazana J, Fine LG, Kitamura M. Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect. J Biol Chem 2002; 277:41093-700.
-
(2002)
J Biol Chem
, vol.277
, pp. 41093-41700
-
-
Xu, Q.1
Konta, T.2
Furusu, A.3
Nakayama, K.4
Lucio-Cazana, J.5
Fine, L.G.6
Kitamura, M.7
-
33
-
-
0142039878
-
The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation
-
Li M, Zhou JY, Ge Y, Matherly LH, Wu GS. The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation. J Biol Chem 2003; 278:41059-68.
-
(2003)
J Biol Chem
, vol.278
, pp. 41059-41068
-
-
Li, M.1
Zhou, J.Y.2
Ge, Y.3
Matherly, L.H.4
Wu, G.S.5
-
34
-
-
0033547306
-
Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth
-
Wu GS, Burns TF, McDonald ER, Meng RD, Kao G, Muschel R, Yen T, El-Deiry WS. Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth. Oncogene 1999; 18:6411-8.
-
(1999)
Oncogene
, vol.18
, pp. 6411-6418
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
Meng, R.D.4
Kao, G.5
Muschel, R.6
Yen, T.7
El-Deiry, W.S.8
-
35
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
Sax JK, Fei P, Murphy ME, Bernhard E, Korsmeyer SJ, El-Deiry WS. BID regulation by p53 contributes to chemosensitivity. Nat Cell Biol 2002; 4:842-9.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
36
-
-
0037012034
-
Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line
-
Wu GS, Ding Z. Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line. Oncogene 2002; 21:1-8.
-
(2002)
Oncogene
, vol.21
, pp. 1-8
-
-
Wu, G.S.1
Ding, Z.2
-
37
-
-
0032580334
-
Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity
-
Wu GS, Saftig P, Peters C, El-Deiry WS. Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene 1998; 16:2177-83.
-
(1998)
Oncogene
, vol.16
, pp. 2177-2183
-
-
Wu, G.S.1
Saftig, P.2
Peters, C.3
El-Deiry, W.S.4
-
38
-
-
0346118942
-
Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity
-
Ge Y, Jensen TL, Matherly LH, Taub JW. Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity. J Biol Chem 2003; 278:49901-10.
-
(2003)
J Biol Chem
, vol.278
, pp. 49901-49910
-
-
Ge, Y.1
Jensen, T.L.2
Matherly, L.H.3
Taub, J.W.4
-
39
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
Szak ST, Mays D, Pietenpol JA. Kinetics of p53 binding to promoter sites in vivo. Mol Cell Biol 2001; 21:3375-86.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
40
-
-
0037417281
-
PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression
-
Yin Y, Liu YX, Jin YJ, Hall EJ, Barrett JC. PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression. Nature 2003; 422:527-31.
-
(2003)
Nature
, vol.422
, pp. 527-531
-
-
Yin, Y.1
Liu, Y.X.2
Jin, Y.J.3
Hall, E.J.4
Barrett, J.C.5
-
41
-
-
0041836252
-
Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53
-
Ueda K, Arakawa H, Nakamura Y. Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53. Oncogene 2003; 22:5586-91.
-
(2003)
Oncogene
, vol.22
, pp. 5586-5591
-
-
Ueda, K.1
Arakawa, H.2
Nakamura, Y.3
-
42
-
-
0028971143
-
MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt K, Frech K, Karas H, Wingender E, Werner T. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 1995; 23:4878-84.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
43
-
-
0033970533
-
Dual specificity phosphatases: A gene family for control of MAP kinase function
-
Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 2000; 14:6-16.
-
(2000)
FASEB J
, vol.14
, pp. 6-16
-
-
Camps, M.1
Nichols, A.2
Arkinstall, S.3
-
44
-
-
4444240191
-
The Functional Interactions between the p53 and MAPK Signaling Pathways
-
Wu GS. The Functional Interactions Between the p53 and MAPK Signaling Pathways. Cancer Biol Ther 2004; 3:156-61.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 156-161
-
-
Wu, G.S.1
|