The mechanism of SR95531 inhibition at GABAA receptors examined in human α1β1 and α1β 1γ2S receptors

Journal of Neurochemistry

Volumn 94, Issue 2, 2005, Pages 491-501

  Lindquist, Catarina E L ^a   Laver, Derek R ^b   Birnir, Bryndis ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

GABAA receptors; Gabazine; Gating models; Patch clamp; Sf9 cells; SR95531

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; HUMAN; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SYNAPSE;

ANIMALS; CELL LINE; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE TRANSFER TECHNIQUES; HUMANS; INHIBITORY CONCENTRATION 50; ION CHANNEL GATING; MACROMOLECULAR SUBSTANCES; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; PYRIDAZINES; RECEPTORS, GABA-A; SPODOPTERA;

EID: 22244471649     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03240.x     Document Type: Article

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