-
1
-
-
0030113274
-
Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle
-
Spencer T, Biederman J, Wilens T, et al. Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle. Child Adol Psychiatry 1996; 35: 409-32
-
(1996)
Child Adol Psychiatry
, vol.35
, pp. 409-432
-
-
Spencer, T.1
Biederman, J.2
Wilens, T.3
-
2
-
-
0032492176
-
Attention-deficit hyperactivity disorder and hyperkinetic disorder
-
Swanson JM, Sergeant JA, Sonuga-Barke EJS, et al. Attention-deficit hyperactivity disorder and hyperkinetic disorder. Lancet 1998; 351: 429-33
-
(1998)
Lancet
, vol.351
, pp. 429-433
-
-
Swanson, J.M.1
Sergeant, J.A.2
Sonuga-Barke, E.J.S.3
-
3
-
-
0021974873
-
Follow-up studies on outcome of hyperactive children
-
Weiss G. Follow-up studies on outcome of hyperactive children. Psychopharmacol Bull 1985; 21: 169-77
-
(1985)
Psychopharmacol Bull
, vol.21
, pp. 169-177
-
-
Weiss, G.1
-
5
-
-
0036920908
-
Management of ADHD in adults
-
Adler LA, Chua HC. Management of ADHD in adults. J Clin Psychiatry 2002; 63 Suppl. 12: 29-35
-
(2002)
J Clin Psychiatry
, vol.63
, Issue.12 SUPPL.
, pp. 29-35
-
-
Adler, L.A.1
Chua, H.C.2
-
6
-
-
0025324595
-
The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study
-
Barkley FA, Fischer M, Edelbrock CS, et al. The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry 1990; 29: 546-57
-
(1990)
J Am Acad Child Adolesc Psychiatry
, vol.29
, pp. 546-557
-
-
Barkley, F.A.1
Fischer, M.2
Edelbrock, C.S.3
-
7
-
-
0023502040
-
Psychiatric comorbidity in patients with attention deficit disorder: A controlled study
-
Munir K, Biederman J, Knee D. Psychiatric comorbidity in patients with attention deficit disorder: a controlled study. J Am Acad Child Adolesc Psychiatry 1987; 26: 844-8
-
(1987)
J Am Acad Child Adolesc Psychiatry
, vol.26
, pp. 844-848
-
-
Munir, K.1
Biederman, J.2
Knee, D.3
-
8
-
-
0025756107
-
Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders
-
Biederman J, Newcorn J, Sprich S. Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders. Am J Psychiatry 1991; 148: 564-77
-
(1991)
Am J Psychiatry
, vol.148
, pp. 564-577
-
-
Biederman, J.1
Newcorn, J.2
Sprich, S.3
-
9
-
-
0036928919
-
Overview and neurobiology of attention-deficit/hyperactivity disorder
-
Spencer TJ, Biederman J, Wilens TE, et al. Overview and neurobiology of attention-deficit/hyperactivity disorder. J Clin Psychiatry 2002; 63 Suppl. 12: 3-9
-
(2002)
J Clin Psychiatry
, vol.63
, Issue.12 SUPPL.
, pp. 3-9
-
-
Spencer, T.J.1
Biederman, J.2
Wilens, T.E.3
-
10
-
-
0036892938
-
Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: Results from imaging studies
-
Volkow ND, Fowler JS, Wang G-J, et al. Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies. Eur Neuropsychopharmacol 2002; 12: 557-66
-
(2002)
Eur Neuropsychopharmacol
, vol.12
, pp. 557-566
-
-
Volkow, N.D.1
Fowler, J.S.2
Wang, G.-J.3
-
11
-
-
0027535205
-
Molecular characterization of the dopamine transporter
-
Giros B, Caron MG. Molecular characterization of the dopamine transporter. Trends Pharmacol Sci 1993; 14: 43-9
-
(1993)
Trends Pharmacol Sci
, vol.14
, pp. 43-49
-
-
Giros, B.1
Caron, M.G.2
-
12
-
-
0031460272
-
Pharmacology of methylphenidate, amphetamine enantiomers and pemoline in attention-deficit hyperactivity disorder: A review
-
Patrick KS, Markowitz JS. Pharmacology of methylphenidate, amphetamine enantiomers and pemoline in attention-deficit hyperactivity disorder: a review. Hum Psychopharmacol 1997; 12: 527-46
-
(1997)
Hum Psychopharmacol
, vol.12
, pp. 527-546
-
-
Patrick, K.S.1
Markowitz, J.S.2
-
14
-
-
0034758620
-
Pharmacokinetic and pharmacodynamic drug interactions in the treatment of attention-deficit hyperactivity disorder
-
Markowitz JS, Patrick KS. Pharmacokinetic and pharmacodynamic drug interactions in the treatment of attention-deficit hyperactivity disorder. Clin Pharmacokinet 2001; 40: 753-72
-
(2001)
Clin Pharmacokinet
, vol.40
, pp. 753-772
-
-
Markowitz, J.S.1
Patrick, K.S.2
-
15
-
-
17544402536
-
Once-a-day Concerta methylphenidate versus three-times-daily methylphenidate in laboratory and natural settings
-
Pelham WE, Gnagy EM, Burrows-Maclean L, et al. Once-a-day Concerta methylphenidate versus three-times-daily methylphenidate in laboratory and natural settings [abstract]. Pediatrics 2001; 107: E105
-
(2001)
Pediatrics
, vol.107
-
-
Pelham, W.E.1
Gnagy, E.M.2
Burrows-Maclean, L.3
-
16
-
-
0036033841
-
Extended-release methylphenidate (Ritalin LA)
-
Lyseng-Williamson KA, Keating GM. Extended-release methylphenidate (Ritalin LA). Drugs 2002; 62: 2251-9
-
(2002)
Drugs
, vol.62
, pp. 2251-2259
-
-
Lyseng-Williamson, K.A.1
Keating, G.M.2
-
17
-
-
0036844044
-
SLI381 (Adderall XR), a two-component, extended-release formulation of mixed amphetamine salts: Bioavailability of three test formulations and comparison of fasted, fed, and sprinkled administration
-
Tulloch SJ, Zhang Y, McLean A, et al. SLI381 (Adderall XR), a two-component, extended-release formulation of mixed amphetamine salts: bioavailability of three test formulations and comparison of fasted, fed, and sprinkled administration. Pharmacotherapy 2002; 22: 1405-15
-
(2002)
Pharmacotherapy
, vol.22
, pp. 1405-1415
-
-
Tulloch, S.J.1
Zhang, Y.2
McLean, A.3
-
18
-
-
0343145695
-
Interactions of amphetamine analogs with human liver CYP2D6
-
Wu D, Otton SV, Inaba T, et al. Interactions of amphetamine analogs with human liver CYP2D6. Biochem Pharmacol 1997; 53: 1605-12
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1605-1612
-
-
Wu, D.1
Otton, S.V.2
Inaba, T.3
-
20
-
-
0031459908
-
Antidepressants in the treatment of attention-deficit/hyperactivity disorder
-
Popper CW. Antidepressants in the treatment of attention-deficit/ hyperactivity disorder. J Clin Psychiatry 1997; 58 Suppl. 14: 14-29
-
(1997)
J Clin Psychiatry
, vol.58
, Issue.14 SUPPL.
, pp. 14-29
-
-
Popper, C.W.1
-
21
-
-
0019997797
-
A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain
-
Wong DT, Threlkeld PG, Best KL, et al. A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J Pharmacol Exp Ther 1982; 222: 61-5
-
(1982)
J Pharmacol Exp Ther
, vol.222
, pp. 61-65
-
-
Wong, D.T.1
Threlkeld, P.G.2
Best, K.L.3
-
22
-
-
0036848458
-
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: A potential mechanism for efficacy in attention deficit/hyperactivity disorder
-
Bymaster FP, Katner JS, Nelson DL, et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 2002; 27: 699-711
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 699-711
-
-
Bymaster, F.P.1
Katner, J.S.2
Nelson, D.L.3
-
23
-
-
0031977617
-
Effectiveness and tolerability of tomoxetine in adults with attention deficit hyper-activity disorder
-
Spencer T, Biederman J, Wilens T, et al. Effectiveness and tolerability of tomoxetine in adults with attention deficit hyper-activity disorder. Am J Psychiatry 1998; 155: 693-5
-
(1998)
Am J Psychiatry
, vol.155
, pp. 693-695
-
-
Spencer, T.1
Biederman, J.2
Wilens, T.3
-
24
-
-
12244298956
-
Atomoxetine in adults with ADHD: Two randomized, placebo-controlled studies
-
Michelson D, Adler L, Spencer T, et al. Atomoxetine in adults with ADHD: two randomized, placebo-controlled studies. Biol Psychiatry 2003; 53: 112-20
-
(2003)
Biol Psychiatry
, vol.53
, pp. 112-120
-
-
Michelson, D.1
Adler, L.2
Spencer, T.3
-
25
-
-
0035511622
-
Atomoxetine in the treatment of children and adolescents with ADHD: A random-ized, placebo-controlled dose-response study
-
Michelson D, Faries DE, Wernicke J, et al. Atomoxetine in the treatment of children and adolescents with ADHD: a random-ized, placebo-controlled dose-response study [abstract]. Pediatrics 2001; 108: E83
-
(2001)
Pediatrics
, vol.108
-
-
Michelson, D.1
Faries, D.E.2
Wernicke, J.3
-
26
-
-
0036842531
-
Once-daily atomoxetine treatment for children and adolescents with attention deficit hyperactivity disorder: A randomized, placebo-controlled study
-
Michelson D, Allen AJ, Busner J, et al. Once-daily atomoxetine treatment for children and adolescents with attention deficit hyperactivity disorder: a randomized, placebo-controlled study. Am J Psychiatry 2002; 159: 1896-901
-
(2002)
Am J Psychiatry
, vol.159
, pp. 1896-1901
-
-
Michelson, D.1
Allen, A.J.2
Busner, J.3
-
27
-
-
0036633805
-
Atomoxetine and methylphenidate treatment in children with ADHD: A prospective, randomized, open-label trial
-
Kratochvil CJ, Heiligenstein JH, Dittmann R, et al. Atomoxetine and methylphenidate treatment in children with ADHD: a prospective, randomized, open-label trial. Am Acad Child Adolesc Psychiatry 2002; 41: 776-84
-
(2002)
Am Acad Child Adolesc Psychiatry
, vol.41
, pp. 776-784
-
-
Kratochvil, C.J.1
Heiligenstein, J.H.2
Dittmann, R.3
-
28
-
-
0013499111
-
Disposition and metabolic fate of atomoxetine hydrochloride: The role of CYP2D6 in human disposition and metabolism
-
Sauer JM, Ponsler GD, Mattiuz EL, et al. Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism. Drug Metab Dispos 2003; 31: 98-107
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 98-107
-
-
Sauer, J.M.1
Ponsler, G.D.2
Mattiuz, E.L.3
-
29
-
-
0021915377
-
Single-dose and steady-state pharmacokinetics of tomoxetine in normal subjects
-
Farid NA, Bergstrom RF, Ziege EA, et al. Single-dose and steady-state pharmacokinetics of tomoxetine in normal subjects. J Clin Pharmacol 1985; 25: 296-301
-
(1985)
J Clin Pharmacol
, vol.25
, pp. 296-301
-
-
Farid, N.A.1
Bergstrom, R.F.2
Ziege, E.A.3
-
30
-
-
0036838952
-
Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics
-
Belle DJ, Ernest S, Sauer JM, et al. Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics. J Clin Pharmacol 2002; 42: 1-9
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 1-9
-
-
Belle, D.J.1
Ernest, S.2
Sauer, J.M.3
-
31
-
-
0002888510
-
Human cytochrome P450 enzymes
-
Ortiz de Montellano PR, editor. New York: Plenum Press
-
Guengerich FP. Human cytochrome P450 enzymes. In: Ortiz de Montellano PR, editor. Cytochrome P450: structure, mechanism, and biochemistry. New York: Plenum Press, 1995: 473-535
-
(1995)
Cytochrome P450: Structure, Mechanism, and Biochemistry
, pp. 473-535
-
-
Guengerich, F.P.1
-
32
-
-
0031038038
-
Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
-
Sachse C, Brockmoller J, Bauer S, et al. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 1997; 60: 284-95
-
(1997)
Am J Hum Genet
, vol.60
, pp. 284-295
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
-
33
-
-
0028942981
-
Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
-
Agundez JA, Ledesma MC, Ladero JM, et al. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995; 57: 265-9
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 265-269
-
-
Agundez, J.A.1
Ledesma, M.C.2
Ladero, J.M.3
-
34
-
-
0037374404
-
Effect of liver impairment on the pharmacokinetics of atomoxetine and its metabolites
-
Chalon S, Desager JP, DeSante K, et al. Effect of liver impairment on the pharmacokinetics of atomoxetine and its metabolites. Clin Pharmacol Ther 2003; 73: 178-91
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 178-191
-
-
Chalon, S.1
Desager, J.P.2
DeSante, K.3
-
35
-
-
9144240390
-
Disposition and metabolic fate of atomoxetine hydrochloride: Clinical drug-drug interaction prediction and outcome
-
Sauer JM, Long AJ, Ring B, et al. Disposition and metabolic fate of atomoxetine hydrochloride: clinical drug-drug interaction prediction and outcome. J Pharmacol and Exp Ther 2004; 308: 410-8
-
(2004)
J Pharmacol and Exp Ther
, vol.308
, pp. 410-418
-
-
Sauer, J.M.1
Long, A.J.2
Ring, B.3
-
36
-
-
0038556715
-
Atomoxetine pharmacokinetics in children with attention deficit hyperactivity disorder
-
Witcher JW, Long AJ, Sauer JM, et al. Atomoxetine pharmacokinetics in children with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol 2003; 13: 53-64
-
(2003)
J Child Adolesc Psychopharmacol
, vol.13
, pp. 53-64
-
-
Witcher, J.W.1
Long, A.J.2
Sauer, J.M.3
-
38
-
-
0018900001
-
A family and population study of the genetic polymorphism of the debrisoquine oxidation in a white British population
-
Evans DAP, Maghoub A, Sloan TP, et al. A family and population study of the genetic polymorphism of the debrisoquine oxidation in a white British population. J Med Genet 1980; 17: 102-5
-
(1980)
J Med Genet
, vol.17
, pp. 102-105
-
-
Evans, D.A.P.1
Maghoub, A.2
Sloan, T.P.3
-
39
-
-
0023701452
-
Polymorphic debrisoquine hydroxylation in 757 Swedish subjects
-
Steiner E, Bertilsson L, Sawe J, et al. Polymorphic debrisoquine hydroxylation in 757 Swedish subjects. Clin Pharmacol Ther 1988; 44: 431-5
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Sawe, J.3
-
40
-
-
85069020472
-
Atomoxetine absolute bioavailability and effects of food, Maalox or omeprazole on atomoxetine bioavailability
-
Oct 21-25; Denver
-
DeSante K, Long A, Smith B, et al. Atomoxetine absolute bioavailability and effects of food, Maalox or omeprazole on atomoxetine bioavailability. AAPS Annual Meeting and Exposition; 2001 Oct 21-25; Denver
-
(2001)
AAPS Annual Meeting and Exposition
-
-
DeSante, K.1
Long, A.2
Smith, B.3
-
41
-
-
85069011081
-
Tissue disposition of 14C-tomoxetine in male Fischer 344 rats following a single oral dose administration
-
Apr 18-20; St Louis
-
Herman JL, Kou F, Sauer JM, et al. Tissue disposition of 14C-tomoxetine in male Fischer 344 rats following a single oral dose administration. Society for Whole-Body Autoradiography Meeting; 1999 Apr 18-20; St Louis
-
(1999)
Society for Whole-Body Autoradiography Meeting
-
-
Herman, J.L.1
Kou, F.2
Sauer, J.M.3
-
42
-
-
85069033584
-
Placental transfer and milk excretion in rats after a single oral 50 mg/kg dose of [14C]atomoxetine administered as the hydrochloride salt
-
Paris
-
Hamilton MM, Herman JL, Kou F, et al. Placental transfer and milk excretion in rats after a single oral 50 mg/kg dose of [14C]atomoxetine administered as the hydrochloride salt. European Society for Whole Body Autoradiography; 2000, Paris
-
(2000)
European Society for Whole Body Autoradiography
-
-
Hamilton, M.M.1
Herman, J.L.2
Kou, F.3
-
43
-
-
0036181544
-
Identification of the human cytochromes P450 responsible for atomoxetine metabolism
-
Ring BJ, Gillespie JS, Eckstein JA, et al. Identification of the human cytochromes P450 responsible for atomoxetine metabolism. Drug Metab Dispos 2002; 30: 319-23
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 319-323
-
-
Ring, B.J.1
Gillespie, J.S.2
Eckstein, J.A.3
-
44
-
-
0003518480
-
-
New York: John Wiley and Sons, Inc.
-
Segel IH. Enzyme kinetics. New York: John Wiley and Sons, Inc., 1975
-
(1975)
Enzyme Kinetics
-
-
Segel, I.H.1
-
46
-
-
0027162344
-
Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites
-
Gehlert DR, Gackenheimer SL, Robertson DW. Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites. Neurosci Lett 1993; 157: 203-6
-
(1993)
Neurosci Lett
, vol.157
, pp. 203-206
-
-
Gehlert, D.R.1
Gackenheimer, S.L.2
Robertson, D.W.3
-
47
-
-
0028988546
-
Comparison of (R)-[3H]tomoxetine and (R/S)-[3H]nisoxetine binding in rat brain
-
Gehlert DR, Schober DA, Gackenheimer SL. Comparison of (R)-[3H]tomoxetine and (R/S)-[3H]nisoxetine binding in rat brain. J Neurochem 1995; 64: 2792-800
-
(1995)
J Neurochem
, vol.64
, pp. 2792-2800
-
-
Gehlert, D.R.1
Schober, D.A.2
Gackenheimer, S.L.3
-
48
-
-
0036644683
-
Comparison of the subjective, physiological, and psychomotor effects of atomoxetine and methylphenidate in light drug users
-
Heil SH, Holmes HW, Bickel WK, et al. Comparison of the subjective, physiological, and psychomotor effects of atomoxetine and methylphenidate in light drug users. Drug Alcohol Depend 2002; 67: 149-56
-
(2002)
Drug Alcohol Depend
, vol.67
, pp. 149-156
-
-
Heil, S.H.1
Holmes, H.W.2
Bickel, W.K.3
-
49
-
-
32744463254
-
Strattera™ (atomoxetine HCl), an inhibitor of the norepinephrine transporter. I: The preparation of C-14 labeled atomoxetine, and two of its metabolites; II: the preparation and biological evaluation of some additional putative metabolites of atomoxetine
-
Dean DC, Filer CN, McCarthy KE, editors. New York: John Wiley and Sons, Inc.
-
Wheeler WJ, Bymaster FP, Calligaro DO, et al. Strattera™ (atomoxetine HCl), an inhibitor of the norepinephrine transporter. I: the preparation of C-14 labeled atomoxetine, and two of its metabolites; II: The preparation and biological evaluation of some additional putative metabolites of atomoxetine. In: Dean DC, Filer CN, McCarthy KE, editors. Synthesis and applications of isotopically labelled compounds. Vol 8. New York: John Wiley and Sons, Inc., 2004: 357-60
-
(2004)
Synthesis and Applications of Isotopically Labelled Compounds
, vol.8
, pp. 357-360
-
-
Wheeler, W.J.1
Bymaster, F.P.2
Calligaro, D.O.3
-
50
-
-
0020622312
-
Antagonism by tomoxetine of the depletion of norepinephrine and epinephrine in rat brain by alpha-methyl-m-tyrosine
-
Fuller RW, Hemrick-Luecke SK. Antagonism by tomoxetine of the depletion of norepinephrine and epinephrine in rat brain by alpha-methyl-m-tyrosine. Res Commun Chem Path Pharmacol 1983; 41: 169-72
-
(1983)
Res Commun Chem Path Pharmacol
, vol.41
, pp. 169-172
-
-
Fuller, R.W.1
Hemrick-Luecke, S.K.2
-
51
-
-
0038685707
-
Disposition and metabolic fate of atomoxetine hydrochloride: Pharmacokinetics, metabolism, and excretion in the fischer 344 rat and beagle dog
-
Mattiuz EL, Ponsler GD, Barbuch RJ, et al. Disposition and metabolic fate of atomoxetine hydrochloride: pharmacokinetics, metabolism, and excretion in the fischer 344 rat and beagle dog. Drug Metab Dispos 2003; 31: 88-97
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 88-97
-
-
Mattiuz, E.L.1
Ponsler, G.D.2
Barbuch, R.J.3
-
52
-
-
0031837755
-
Drug discrimination in metham-phetamine-trained monkeys: Agonist and antagonist effects of dopaminergic drugs
-
Tidey JW, Bergman J. Drug discrimination in metham-phetamine-trained monkeys: agonist and antagonist effects of dopaminergic drugs. J Pharmacol Exp Ther 1998; 285: 1163-74
-
(1998)
J Pharmacol Exp Ther
, vol.285
, pp. 1163-1174
-
-
Tidey, J.W.1
Bergman, J.2
-
53
-
-
0036929584
-
Safety profile of atomoxetine in the treatment of children and adolescents with ADHD
-
Wernicke JF, Kratochvil CJ. Safety profile of atomoxetine in the treatment of children and adolescents with ADHD. J Clin Psychiatry 2002; 63 Suppl. 12: 50-5
-
(2002)
J Clin Psychiatry
, vol.63
, Issue.12 SUPPL.
, pp. 50-55
-
-
Wernicke, J.F.1
Kratochvil, C.J.2
-
54
-
-
4243430961
-
Safety of tomoxetine in clinical trials
-
Wernicke JF, Allen AJ, Faries D, et al. Safety of tomoxetine in clinical trials [abstract]. Biol Psychiatry 2001; 49 (8 Suppl.): 159S
-
(2001)
Biol Psychiatry
, vol.49
, Issue.8 SUPPL.
-
-
Wernicke, J.F.1
Allen, A.J.2
Faries, D.3
-
55
-
-
0036935774
-
Results from 2 proof-of-concept, placebo-controlled studies of atomoxetine in children with attention-deficit/hyperactivity disorder
-
Spencer T, Heiligenstein JH, Biederman J, et al. Results from 2 proof-of-concept, placebo-controlled studies of atomoxetine in children with attention-deficit/hyperactivity disorder. J Clin Psychiatry 2002; 63: 1140-7
-
(2002)
J Clin Psychiatry
, vol.63
, pp. 1140-1147
-
-
Spencer, T.1
Heiligenstein, J.H.2
Biederman, J.3
-
56
-
-
0043124593
-
Cardiovascular effects of atomoxetine in children, adolescents, and adults
-
Wernicke JF, Faries D, Girod D, et al. Cardiovascular effects of atomoxetine in children, adolescents, and adults. Drug Saf 2003; 26: 729-40
-
(2003)
Drug Saf
, vol.26
, pp. 729-740
-
-
Wernicke, J.F.1
Faries, D.2
Girod, D.3
-
57
-
-
0021320065
-
An early phase II clinical trial of tomoxetine (LY139603) in the treatment of newly admitted depressed patients
-
Chouinard G, Annable L, Bradwejn J. An early phase II clinical trial of tomoxetine (LY139603) in the treatment of newly admitted depressed patients. Psychopharmacologia 1984; 83: 126-8
-
(1984)
Psychopharmacologia
, vol.83
, pp. 126-128
-
-
Chouinard, G.1
Annable, L.2
Bradwejn, J.3
-
58
-
-
0021926971
-
Clinical pharmacology of tomoxetine, a potential antidepressant
-
Zerbe RL, Rowe H, Enas GG, et al. Clinical pharmacology of tomoxetine, a potential antidepressant. J Pharmacol Exp Ther 1985; 232: 139-43
-
(1985)
J Pharmacol Exp Ther
, vol.232
, pp. 139-143
-
-
Zerbe, R.L.1
Rowe, H.2
Enas, G.G.3
-
59
-
-
4243594098
-
Safety and efficacy of atomoxetine in pediatric CYP2D6 extensive and poor metabolizers
-
Allen AJ, Wernicke JF, Dunn D, et al. Safety and efficacy of atomoxetine in pediatric CYP2D6 extensive and poor metabolizers. Biol Psychiatry 2001; 49 (8 Suppl.): 37S
-
(2001)
Biol Psychiatry
, vol.49
, Issue.8 SUPPL.
-
-
Allen, A.J.1
Wernicke, J.F.2
Dunn, D.3
-
60
-
-
0031979755
-
Metabolism of the newer antidepressants: An overview of the pharmacological and pharmacokinetic implications
-
Caccia S. Metabolism of the newer antidepressants: an overview of the pharmacological and pharmacokinetic implications. Clin Pharmacokinet 1998; 34: 281-302
-
(1998)
Clin Pharmacokinet
, vol.34
, pp. 281-302
-
-
Caccia, S.1
-
61
-
-
0031025875
-
Clinically relevant pharmacology of selective serotonin reuptake inhibitors: An overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism
-
Preskorn SH. Clinically relevant pharmacology of selective serotonin reuptake inhibitors: an overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism. Clin Pharmacokinet 1997; 32S: 1-21
-
(1997)
Clin Pharmacokinet
, vol.32 S
, pp. 1-21
-
-
Preskorn, S.H.1
-
62
-
-
0027167470
-
Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
-
Brøsen K, Hansen JG, Nielsen KK, et al. Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine. Eur J Clin Pharmacol 1993; 44: 349-55
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 349-355
-
-
Brøsen, K.1
Hansen, J.G.2
Nielsen, K.K.3
-
63
-
-
0031225744
-
Paroxetine potentiates the central nervous system side effects of perphenazine: Contribution of cytochrome P4502D6 inhibition in vivo
-
Özdemir V, Naranjo CA, Herrmann N, et al. Paroxetine potentiates the central nervous system side effects of perphenazine: contribution of cytochrome P4502D6 inhibition in vivo. Clin Pharmacol Ther 1997; 62: 334-47
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 334-347
-
-
Özdemir, V.1
Naranjo, C.A.2
Herrmann, N.3
-
64
-
-
0030791275
-
Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers
-
Alderman J, Preskorn SH, Greenblatt DJ, et al. Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers. J Clin Psychopharmacol 1997; 17: 284-91
-
(1997)
J Clin Psychopharmacol
, vol.17
, pp. 284-291
-
-
Alderman, J.1
Preskorn, S.H.2
Greenblatt, D.J.3
-
65
-
-
0035029210
-
Paroxetine affects metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers
-
Hemeryck A, Lefebvre RA, De Vriendt C, et al, editor. Paroxetine affects metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers. Drug Metab Dispos 2001; 29: 656-63
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 656-663
-
-
Hemeryck, A.1
Lefebvre, R.A.2
De Vriendt, C.3
-
66
-
-
0028842707
-
The effects of selective serotonin reuptake inhibitors and their metablites on S-mephenytoin 4′-hydroxylase activity in human liver microsomes
-
Kobayashi K, Yamamoto T, Chiba K, et al. The effects of selective serotonin reuptake inhibitors and their metablites on S-mephenytoin 4′-hydroxylase activity in human liver microsomes. Br J Clin Pharmacol 1995; 40: 481-5
-
(1995)
Br J Clin Pharmacol
, vol.40
, pp. 481-485
-
-
Kobayashi, K.1
Yamamoto, T.2
Chiba, K.3
-
67
-
-
0028898816
-
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: Comparison with other selective serotonin reuptake inhibitor antidepressants
-
von Moltke LL, Greenblatt DJ, Court MH, et al. Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. J Clin Psychopharmacol 1995; 15: 125-31
-
(1995)
J Clin Psychopharmacol
, vol.15
, pp. 125-131
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Court, M.H.3
-
68
-
-
0029738965
-
Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine
-
Jeppesen U, Gram LF, Vistisen K, et al. Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine. Eur J Clin Pharmacol 1996; 51: 73-8
-
(1996)
Eur J Clin Pharmacol
, vol.51
, pp. 73-78
-
-
Jeppesen, U.1
Gram, L.F.2
Vistisen, K.3
-
69
-
-
0031399764
-
Paroxetine does not affect the cardiac safety and pharmacokinetics of terfenadine in healthy adult men
-
Martin DE, Zussman BD, Everitt DE, et al. Paroxetine does not affect the cardiac safety and pharmacokinetics of terfenadine in healthy adult men. J Clin Psychopharmacol 1997; 17: 451-9
-
(1997)
J Clin Psychopharmacol
, vol.17
, pp. 451-459
-
-
Martin, D.E.1
Zussman, B.D.2
Everitt, D.E.3
-
70
-
-
0030706197
-
Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: Studies of phenytoin p-hydroxylation
-
Schmider J, Greenblatt DJ, von Moltke LL, et al. Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: studies of phenytoin p-hydroxylation. Br J Clin Pharmacol 1997; 44: 495-8
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 495-498
-
-
Schmider, J.1
Greenblatt, D.J.2
Von Moltke, L.L.3
-
71
-
-
0032965977
-
Inhibition of CYP2C9 by selective serotonin reuptake inhibitors: In vitro studies with tolbutamide and (S)-warfarin using human liver microsomes
-
Hemeryck A, De Vriendt C, Belpaire FM. Inhibition of CYP2C9 by selective serotonin reuptake inhibitors: in vitro studies with tolbutamide and (S)-warfarin using human liver microsomes. Eur J Clin Pharmacol 1999; 54: 947-51
-
(1999)
Eur J Clin Pharmacol
, vol.54
, pp. 947-951
-
-
Hemeryck, A.1
De Vriendt, C.2
Belpaire, F.M.3
-
72
-
-
85069012796
-
Atomoxetine does not alter the plasma pharmacokinetics of desipramine in healthy subjects
-
Oct 21-25, Denver
-
Long A, Witcher J, Smith B, et al. Atomoxetine does not alter the plasma pharmacokinetics of desipramine in healthy subjects. AAPS Annual Meeting and Exposition; 2001 Oct 21-25, Denver
-
(2001)
AAPS Annual Meeting and Exposition
-
-
Long, A.1
Witcher, J.2
Smith, B.3
-
73
-
-
0031057666
-
Effect of ketoconazole on the pharmacokinetics of imipramine and desipramine in healthy subjects
-
Spina E, Avenoso A, Campo GM, et al. Effect of ketoconazole on the pharmacokinetics of imipramine and desipramine in healthy subjects. Br J Clin Pharmacol 1997; 43: 315-8
-
(1997)
Br J Clin Pharmacol
, vol.43
, pp. 315-318
-
-
Spina, E.1
Avenoso, A.2
Campo, G.M.3
-
74
-
-
85069029913
-
Co-administration of atomoxetine hydrochloride and midazolam results in no clinically significant drug-drug interaction
-
Oct 21-25, Denver
-
Sanburn N, Long A, Witcher J, et al. Co-administration of atomoxetine hydrochloride and midazolam results in no clinically significant drug-drug interaction. AAPS Annual Meeting and Exposition; 2001 Oct 21-25, Denver
-
(2001)
AAPS Annual Meeting and Exposition
-
-
Sanburn, N.1
Long, A.2
Witcher, J.3
-
75
-
-
0024373348
-
Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4
-
Kronbach T, Mathys D, Umeno M, et al. Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. Mol Pharmacol 1989; 36: 89-96
-
(1989)
Mol Pharmacol
, vol.36
, pp. 89-96
-
-
Kronbach, T.1
Mathys, D.2
Umeno, M.3
-
76
-
-
0028357256
-
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
-
Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994; 55: 481-5
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 481-485
-
-
Olkkola, K.T.1
Backman, J.T.2
Neuvonen, P.J.3
-
77
-
-
0033323791
-
Pharmacokinetic and pharmacodynamic consequences of metabolism-based drug interactions with alprazolam, midazolam, and triazolam
-
Yuan R, Flockhart D, Balian J. Pharmacokinetic and pharmacodynamic consequences of metabolism-based drug interactions with alprazolam, midazolam, and triazolam. J Clin Pharmacol 1999; 39: 1109-25
-
(1999)
J Clin Pharmacol
, vol.39
, pp. 1109-1125
-
-
Yuan, R.1
Flockhart, D.2
Balian, J.3
-
79
-
-
0024442372
-
Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese
-
Horai Y, Nakano M, Ishizaki T, et al. Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese. Clin Pharmacol Ther 1989; 46: 198-207
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 198-207
-
-
Horai, Y.1
Nakano, M.2
Ishizaki, T.3
-
80
-
-
0001770653
-
CYP2D6
-
Levy RH, Thummel KE, Trager WF, et al, editors. New York: Lippincott Williams & Wilkins
-
Zanger UM, Eichelbaum M. CYP2D6. In: Levy RH, Thummel KE, Trager WF, et al, editors. Metabolic drug interactions. New York: Lippincott Williams & Wilkins, 2000: 87-94
-
(2000)
Metabolic Drug Interactions
, pp. 87-94
-
-
Zanger, U.M.1
Eichelbaum, M.2
-
81
-
-
0030811291
-
Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians
-
McLellan RA, Oscarson M, Seidegard J, et al. Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians. Pharmacogenetics 1997; 7: 187-91
-
(1997)
Pharmacogenetics
, vol.7
, pp. 187-191
-
-
McLellan, R.A.1
Oscarson, M.2
Seidegard, J.3
-
82
-
-
0033408498
-
Analysis of the CYP2D6 gene mutations and their consequences for enzyme function in a West African population
-
Griese EU, Asante-Poku S, Ofori-Adjei D, et al. Analysis of the CYP2D6 gene mutations and their consequences for enzyme function in a West African population. Pharmacogenetics 1999; 9: 715-23
-
(1999)
Pharmacogenetics
, vol.9
, pp. 715-723
-
-
Griese, E.U.1
Asante-Poku, S.2
Ofori-Adjei, D.3
-
83
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002; 3: 229-43
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
84
-
-
0024379208
-
Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children
-
Evans W, Relling M, Petros W, et al. Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children. Clin Pharmacol Ther 1989; 45: 568-73
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 568-573
-
-
Evans, W.1
Relling, M.2
Petros, W.3
-
85
-
-
0026004805
-
Lower prevalence of the debrisoquin oxidative poor metabolizer phenotype in American black versus white subjects
-
Relling M, Cherrie J, Schell M, et al. Lower prevalence of the debrisoquin oxidative poor metabolizer phenotype in American black versus white subjects. Clin Pharmacol Ther 1991; 50: 308-13
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 308-313
-
-
Relling, M.1
Cherrie, J.2
Schell, M.3
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