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Volumn 31, Issue 1, 2003, Pages 98-107

Disposition and metabolic fate of atomoxetine hydrochloride: The role of CYP2D6 in human disposition and metabolism

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYATOMOXETINE; ATOMOXETINE; CARBON 14; CYTOCHROME P450 2D6; DRUG METABOLITE; NORADRENALIN TRANSPORTER; UNCLASSIFIED DRUG;

EID: 0013499111     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.1.98     Document Type: Article
Times cited : (139)

References (10)
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    • A family and population study of the genetic polymorphism of the debrisoquine oxidation in a white British population
    • Evans DAP, Maghoub A, Sloan TP, Idle JR, and Smith RL (1980) A family and population study of the genetic polymorphism of the debrisoquine oxidation in a white British population. J Med Genet 17:102-105.
    • (1980) J Med Genet , vol.17 , pp. 102-105
    • Evans, D.A.P.1    Maghoub, A.2    Sloan, T.P.3    Idle, J.R.4    Smith, R.L.5
  • 4
  • 6
    • 0035511622 scopus 로고    scopus 로고
    • Atomoxetine in the treatment of children and adolescents with attention-deficit/hyperactivity disorder: A randomized, placebo-controlled, dose-response study
    • Michelson D, Faries D, Wernicke J, Kelsey D, Kendrick K, Sallee FR, Spencer T and the Atomoxetine ADHD Study Group (2001) Atomoxetine in the treatment of children and adolescents with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled, dose-response study. Pediatrics 108:E83.
    • (2001) Pediatrics , vol.108
    • Michelson, D.1    Faries, D.2    Wernicke, J.3    Kelsey, D.4    Kendrick, K.5    Sallee, F.R.6    Spencer, T.7
  • 7
    • 0036181544 scopus 로고    scopus 로고
    • Identification of the human cytochromes P450 responsible for atomoxetine metabolism
    • Ring BJ, Gillespie J, Eckstein JA, and Wrighton SA (2002) Identification of the human cytochromes P450 responsible for atomoxetine metabolism. Drug Metab Dispos 30:319-323.
    • (2002) Drug Metab Dispos , vol.30 , pp. 319-323
    • Ring, B.J.1    Gillespie, J.2    Eckstein, J.A.3    Wrighton, S.A.4
  • 9
    • 0032613125 scopus 로고    scopus 로고
    • Chapter 18. Cytochrome P450 CYP2D6
    • Wolf CR and Smith G (1999) Chapter 18. Cytochrome P450 CYP2D6. IARC Sci Publ (Lyon) 148:209-229.
    • (1999) IARC Sci Publ (Lyon) , vol.148 , pp. 209-229
    • Wolf, C.R.1    Smith, G.2
  • 10
    • 0019997797 scopus 로고
    • A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain
    • Wong DT, Threlkeld PG, Best KL, and Bymaster FP (1982) A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J Pharmacol Exp Ther 222:61-65.
    • (1982) J Pharmacol Exp Ther , vol.222 , pp. 61-65
    • Wong, D.T.1    Threlkeld, P.G.2    Best, K.L.3    Bymaster, F.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.