-
1
-
-
0034628489
-
Maintenance of functional equivalence during paralogous Hox gene evolution
-
GREER, J.M. et al. 2000. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 403: 661-665.
-
(2000)
Nature
, vol.403
, pp. 661-665
-
-
Greer, J.M.1
-
2
-
-
0036534442
-
Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes
-
ZHAO, Y. & S.S. POTTER. 2002. Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes. Dev. Biol. 244: 21-36.
-
(2002)
Dev. Biol.
, vol.244
, pp. 21-36
-
-
Zhao, Y.1
Potter, S.S.2
-
3
-
-
0034628556
-
Developmental genetics. A Hox by any other name
-
DUBOULE, D. 2000. Developmental genetics. A Hox by any other name. Nature 403: 607, 609-610.
-
(2000)
Nature
, vol.403
, pp. 607
-
-
Duboule, D.1
-
4
-
-
0031780878
-
From selectors to realizators
-
PRADEL, J. & R.A. WHITE. 1998. From selectors to realizators. Int. J. Dev. Biol. 42: 417-421.
-
(1998)
Int. J. Dev. Biol.
, vol.42
, pp. 417-421
-
-
Pradel, J.1
White, R.A.2
-
5
-
-
1342306067
-
Morphogens, their identification and regulation
-
TABATA, T. & Y. TAKEI. 2004. Morphogens, their identification and regulation. Development 131: 703-712.
-
(2004)
Development
, vol.131
, pp. 703-712
-
-
Tabata, T.1
Takei, Y.2
-
6
-
-
0014593403
-
Positional information and the spatial pattern of cellular differentiation
-
WOLPERT, L. 1969. Positional information and the spatial pattern of cellular differentiation. J. Theor. Biol. 25: 1-47.
-
(1969)
J. Theor. Biol.
, vol.25
, pp. 1-47
-
-
Wolpert, L.1
-
7
-
-
0023679744
-
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner
-
DRIEVER, W. & C. NUSSLEIN-VOLHARD. 1988. The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54: 95-104.
-
(1988)
Cell
, vol.54
, pp. 95-104
-
-
Driever, W.1
Nusslein-Volhard, C.2
-
8
-
-
0026504525
-
Homeobox genes and axial patterning
-
MCGINNIS, W. & R. KRUMLAUF. 1992. Homeobox genes and axial patterning. Cell 68: 283-302.
-
(1992)
Cell
, vol.68
, pp. 283-302
-
-
Mcginnis, W.1
Krumlauf, R.2
-
9
-
-
0030800352
-
An anteroposterior Dorsal gradient in the Drosophila embryo
-
HUANG, A.M., J. RUSCH & M. LEVINE. 1997. An anteroposterior Dorsal gradient in the Drosophila embryo. Genes Dev. 11: 1963-1973.
-
(1997)
Genes Dev.
, vol.11
, pp. 1963-1973
-
-
Huang, A.M.1
Rusch, J.2
Levine, M.3
-
10
-
-
0036334007
-
Small changes in expression affect predisposition to tumorigenesis
-
YAN, H. et al. 2002. Small changes in expression affect predisposition to tumorigenesis. Nat. Genet. 30: 25-26.
-
(2002)
Nat. Genet.
, vol.30
, pp. 25-26
-
-
Yan, H.1
-
11
-
-
0029793060
-
The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis
-
MAENO, M. et al. 1996. The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis. Blood 88: 1965-7192.
-
(1996)
Blood
, vol.88
, pp. 1965-7192
-
-
Maeno, M.1
-
12
-
-
0035261398
-
Self-renewal versus differentiation, a job for the mighty morphogens
-
ZON, L.I. 2001. Self-renewal versus differentiation, a job for the mighty morphogens. Nat. Immunol. 2: 142-143.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 142-143
-
-
Zon, L.I.1
-
13
-
-
0035257660
-
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
-
BHARDWAJ, G. et al. 2001. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nat. Immunol. 2: 172-180.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 172-180
-
-
Bhardwaj, G.1
-
14
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
SONG, W.J. et al. 1999. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat. Genet. 23: 166-175.
-
(1999)
Nat. Genet.
, vol.23
, pp. 166-175
-
-
Song, W.J.1
-
15
-
-
2642519463
-
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU. 1
-
ROSENBAUER, F. et al. 2004. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU. 1. Nat. Genet. 36: 624-630.
-
(2004)
Nat. Genet.
, vol.36
, pp. 624-630
-
-
Rosenbauer, F.1
-
16
-
-
0031907329
-
Role of PU.1 in hematopoiesis
-
FISHER, R.C. & E.W. SCOTT. 1998. Role of PU.1 in hematopoiesis. Stem Cells 16: 25-37.
-
(1998)
Stem Cells
, vol.16
, pp. 25-37
-
-
Fisher, R.C.1
Scott, E.W.2
-
17
-
-
8644219660
-
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
-
WILSON, A. et al. 2004. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18: 2747-2763.
-
(2004)
Genes Dev.
, vol.18
, pp. 2747-2763
-
-
Wilson, A.1
-
18
-
-
0043239343
-
Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb
-
EMAMBOKUS, N. et al. 2003. Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. Embo J. 22: 4478-4488.
-
(2003)
Embo J.
, vol.22
, pp. 4478-4488
-
-
Emambokus, N.1
-
19
-
-
0036383331
-
HOX and non-HOX homeobox genes in leukemic hematopoiesis
-
OWENS, B.M. & R.G. HAWLEY. 2002. HOX and non-HOX homeobox genes in leukemic hematopoiesis. Stem Cells 20: 364-379.
-
(2002)
Stem Cells
, vol.20
, pp. 364-379
-
-
Owens, B.M.1
Hawley, R.G.2
-
20
-
-
0036142691
-
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
-
PINEAULT, N. et al. 2002. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp. Hematol. 30: 49-57.
-
(2002)
Exp. Hematol.
, vol.30
, pp. 49-57
-
-
Pineault, N.1
-
21
-
-
0026485281
-
Homeobox genes in normal hematopoiesis and leukemia
-
LAWRENCE, H.J. & C. LARGMAN. 1992. Homeobox genes in normal hematopoiesis and leukemia. Blood 80: 2445-2453.
-
(1992)
Blood
, vol.80
, pp. 2445-2453
-
-
Lawrence, H.J.1
Largman, C.2
-
22
-
-
0028079924
-
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
-
SAUVAGEAU, G. et al. 1994. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc. Natl. Acad. Sci. USA 91: 12223-12227.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12223-12227
-
-
Sauvageau, G.1
-
23
-
-
0037023528
-
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
-
ANTONCHUK, J., G. SAUVAGEAU & R.K. HUMPHRIES. 2002. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109: 39-45.
-
(2002)
Cell
, vol.109
, pp. 39-45
-
-
Antonchuk, J.1
Sauvageau, G.2
Humphries, R.K.3
-
24
-
-
0029091845
-
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
-
SAUVAGEAU, G. et al. 1995. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 9: 1753-1765.
-
(1995)
Genes Dev.
, vol.9
, pp. 1753-1765
-
-
Sauvageau, G.1
-
25
-
-
0032857035
-
Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size
-
THORSTEINSDOTTIR, U., G. SAUVAGEAU & R.K. HUMPHRIES. 1999. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size. Blood 94: 2605-2612.
-
(1999)
Blood
, vol.94
, pp. 2605-2612
-
-
Thorsteinsdottir, U.1
Sauvageau, G.2
Humphries, R.K.3
-
26
-
-
0034203281
-
Homeobox genes in leukemogenesis
-
BUSKE, C. & R.K. HUMPHRIES. 2000. Homeobox genes in leukemogenesis. Int. J. Hematol. 71: 301-308.
-
(2000)
Int. J. Hematol.
, vol.71
, pp. 301-308
-
-
Buske, C.1
Humphries, R.K.2
-
27
-
-
0034990345
-
Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy
-
KLUMP, H. et al. 2001. Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy. Gene Ther. 8: 811-817.
-
(2001)
Gene Ther.
, vol.8
, pp. 811-817
-
-
Klump, H.1
-
28
-
-
0031022685
-
The cleavage activities of aphthovirus and cardiovirus 2A proteins
-
DONNELLY, M.L. et al. 1997. The cleavage activities of aphthovirus and cardiovirus 2A proteins. J. Gen. Virol. 78: 13-21.
-
(1997)
J. Gen. Virol.
, vol.78
, pp. 13-21
-
-
Donnelly, M.L.1
-
29
-
-
0035015174
-
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: A putative ribosomal 'skip.'
-
DONNELLY, M.L. et al. 2001. Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip.' J. Gen. Virol. 82: 1013-1025.
-
(2001)
J. Gen. Virol.
, vol.82
, pp. 1013-1025
-
-
Donnelly, M.L.1
-
30
-
-
0032830440
-
A model for nonstoichiometric, cotranslational protein scission in eukaryotic ribosomes
-
RYAN, M., M. DONELLY, A. LEWIS, et al. 1999. A model for nonstoichiometric, cotranslational protein scission in eukaryotic ribosomes. Bioorganic Chemistry 27: 55-79.
-
(1999)
Bioorganic Chemistry
, vol.27
, pp. 55-79
-
-
Ryan, M.1
Donelly, M.2
Lewis, A.3
-
32
-
-
0037370740
-
High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation
-
SCHIEDLMEIER, B. et al. 2003. High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation. Blood 101: 1759-1768.
-
(2003)
Blood
, vol.101
, pp. 1759-1768
-
-
Schiedlmeier, B.1
-
33
-
-
11844285633
-
Overexpression of HOXB4 confers a myelo-erythroid differentiation delay in vitro
-
MILSOM, M.D. et al. 2005. Overexpression of HOXB4 confers a myelo-erythroid differentiation delay in vitro. Leukemia 19: 148-153.
-
(2005)
Leukemia
, vol.19
, pp. 148-153
-
-
Milsom, M.D.1
-
34
-
-
0142181988
-
Enforced adenoviral vector-mediated expression of HOXB4 in human umbilical cord blood CD34+ cells promotes myeloid differentiation but not proliferation
-
BRUN, A.C. et al. 2003. Enforced adenoviral vector-mediated expression of HOXB4 in human umbilical cord blood CD34+ cells promotes myeloid differentiation but not proliferation. Mol. Ther. 8: 618-628.
-
(2003)
Mol. Ther.
, vol.8
, pp. 618-628
-
-
Brun, A.C.1
-
35
-
-
22044438605
-
Hoxb4 deficient mice have normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells
-
BRUN, A.C. et al. 2004. Hoxb4 deficient mice have normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells. Blood 12: 12.
-
(2004)
Blood
, vol.12
, pp. 12
-
-
Brun, A.C.1
-
36
-
-
0036566226
-
Differentiation plasticity of hematopoietic cells
-
GRAF, T. 2002. Differentiation plasticity of hematopoietic cells. Blood 99: 3089-3101.
-
(2002)
Blood
, vol.99
, pp. 3089-3101
-
-
Graf, T.1
-
37
-
-
0033605694
-
c-Myc intron element-binding proteins are required for 1, 25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4
-
PAN, Q. & R.U. SIMPSON. 1999. c-Myc intron element-binding proteins are required for 1, 25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4. J. Biol. Chem. 274: 8437-8444.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8437-8444
-
-
Pan, Q.1
Simpson, R.U.2
-
38
-
-
0344442841
-
CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein
-
ZHANG, Y. et al. 2003. CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. Embo J. 22: 6057-6067.
-
(2003)
Embo J.
, vol.22
, pp. 6057-6067
-
-
Zhang, Y.1
-
39
-
-
0029898760
-
Extra specificity from extradenticle: The partnership between HOX and PBX/EXD homeodomain proteins [published erratum appears in Trends Genet 1996 Aug;12(8): 328]
-
MANN, R.S. & S.K. CHAN. 1996. Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins [published erratum appears in Trends Genet 1996 Aug;12(8): 328]. Trends Genet. 12: 258-262.
-
(1996)
Trends Genet.
, vol.12
, pp. 258-262
-
-
Mann, R.S.1
Chan, S.K.2
-
40
-
-
0029939199
-
Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus
-
CHANG, C.P. et al. 1996. Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol. Cell. Biol. 16: 1734-1745.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1734-1745
-
-
Chang, C.P.1
-
41
-
-
0037396675
-
The competitive nature of HOXB4-transduced HSC is limited by PBX1: The generation of ultra-competitive stem cells retaining full differentiation potential
-
KROSL, J. et al. 2003. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity 18: 561-571.
-
(2003)
Immunity
, vol.18
, pp. 561-571
-
-
Krosl, J.1
-
42
-
-
4944252717
-
Molecular interactions involved in HOXB4-induced activation of HSC self-renewal
-
BESLU, N. et al. 2004. Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. Blood 104: 2307-2314.
-
(2004)
Blood
, vol.104
, pp. 2307-2314
-
-
Beslu, N.1
-
43
-
-
2942558501
-
Roles for c-Myc in self-renewal of hematopoietic stem cells
-
SATOH, Y. et al. 2004. Roles for c-Myc in self-renewal of hematopoietic stem cells. J. Biol. Chem. 279: 24986-24993.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24986-24993
-
-
Satoh, Y.1
-
44
-
-
0035069929
-
Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression
-
PAN, Q. & R.U. SIMPSON. 2001. Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression. J. Endocrinol. 169: 153-159.
-
(2001)
J. Endocrinol.
, vol.169
, pp. 153-159
-
-
Pan, Q.1
Simpson, R.U.2
-
45
-
-
1842665674
-
dMyc transforms cells into super-competitors
-
MORENO, E. & K. BASLER. 2004. dMyc transforms cells into super-competitors. Cell 117: 117-129.
-
(2004)
Cell
, vol.117
, pp. 117-129
-
-
Moreno, E.1
Basler, K.2
-
46
-
-
1842816486
-
Drosophila myc regulates organ size by inducing cell competition
-
DE LA COVA, C. et al. 2004. Drosophila myc regulates organ size by inducing cell competition. Cell 117: 107-116.
-
(2004)
Cell
, vol.117
, pp. 107-116
-
-
De La Cova, C.1
-
47
-
-
0038406789
-
Biology of hematopoietic stem cells and progenitors: Implications for clinical application
-
KONDO, M. et al. 2003. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu. Rev. Immunol. 21: 759-806.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 759-806
-
-
Kondo, M.1
-
48
-
-
0035871882
-
Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches
-
NILSSON, S.K., H.M. JOHNSTON & J.A. COVERDALE. 2001. Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood 97: 2293-2299.
-
(2001)
Blood
, vol.97
, pp. 2293-2299
-
-
Nilsson, S.K.1
Johnston, H.M.2
Coverdale, J.A.3
-
49
-
-
0035991663
-
Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo
-
ASKENASY, N. et al. 2002. Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo. Stem Cells 20: 301-310.
-
(2002)
Stem Cells
, vol.20
, pp. 301-310
-
-
Askenasy, N.1
-
50
-
-
0037443457
-
Side effects of retroviral gene transfer into hematopoietic stem cells
-
BAUM, C. et al. 2003. Side effects of retroviral gene transfer into hematopoietic stem cells. Blood 101: 2099-2114.
-
(2003)
Blood
, vol.101
, pp. 2099-2114
-
-
Baum, C.1
-
51
-
-
0037199399
-
Defining gene transfer before expecting gene therapy: Putting the horse before the cart
-
PISLARU, S. et al. 2002. Defining gene transfer before expecting gene therapy: putting the horse before the cart. Circulation 106: 631-636.
-
(2002)
Circulation
, vol.106
, pp. 631-636
-
-
Pislaru, S.1
-
52
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
WU, X. et al. 2003. Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
-
53
-
-
19344375031
-
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
-
MITCHELL, R.S. et al. 2004. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. PLoS Biol. 2: E234.
-
(2004)
PLoS Biol.
, vol.2
-
-
Mitchell, R.S.1
-
54
-
-
0242367234
-
Medicine. Gene therapy - New challenges ahead
-
WILLIAMS, D.A. & C. BAUM. 2003. Medicine. Gene therapy - new challenges ahead. Science 302: 400-401.
-
(2003)
Science
, vol.302
, pp. 400-401
-
-
Williams, D.A.1
Baum, C.2
-
55
-
-
0344413639
-
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
-
KROSL, J. et al. 2003. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat. Med. 9: 1428-1432.
-
(2003)
Nat. Med.
, vol.9
, pp. 1428-1432
-
-
Krosl, J.1
-
56
-
-
0345708270
-
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein
-
AMSELLEM, S. et al. 2003. Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat. Med. 9: 1423-1427.
-
(2003)
Nat. Med.
, vol.9
, pp. 1423-1427
-
-
Amsellem, S.1
-
57
-
-
6344243521
-
Retroviral pseudotransduction for targeted cell manipulation
-
GALLA, M. et al. 2004. Retroviral pseudotransduction for targeted cell manipulation. Mol. Cell. 16:309-315.
-
(2004)
Mol. Cell.
, vol.16
, pp. 309-315
-
-
Galla, M.1
-
58
-
-
8844253952
-
RNA-based gene transfer for adult stem cells and T cells
-
SMITS, E. et al. 2004. RNA-based gene transfer for adult stem cells and T cells. Leukemia 18: 1898-1902.
-
(2004)
Leukemia
, vol.18
, pp. 1898-1902
-
-
Smits, E.1
|