The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle

Journal of Molecular Biology

Volumn 351, Issue 1, 2005, Pages 170-181

  Keough, Dianne T ^a   Brereton, Ian M ^a   De Jersey, John ^a   Guddat, Luke W ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

6 oxopurine phosphoribosyltransferase; Conformational changes in proteins; Protein dynamics; X ray crystallography

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ALPHA HELIX; ARTICLE; BINDING SITE; CATALYSIS; COMPARATIVE STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SUBSTRATE; PRIORITY JOURNAL; TOXOPLASMA GONDII;

TOXOPLASMA GONDII;

EID: 22044439547     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.05.061     Document Type: Article

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