cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells

Hypertension

Volumn 46, Issue 1, 2005, Pages 100-106

  Smyth, Lesley Ann ^a   Brady, Hugh J M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Endothelium

Indexed keywords

CASPASE 8; CELL SURFACE PROTEIN; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLICE INHIBITORY PROTEIN; PROTEIN CMET; UNCLASSIFIED DRUG;

ANOIKIS; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL DEATH; CELL STIMULATION; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

ANOIKIS; ANTIGENS, CD95; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL SURVIVAL; CELLS, CULTURED; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; ENDOTHELIAL CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR AGGREGATION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 21744447505     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000167991.82153.16     Document Type: Article

References (41)

1. Richardson BC, Lalwani ND, Johnson KJ, Marks RM. Fas ligation triggers apoptosis in macrophages but not endothelial cells. Eur J Immunol. 1994;24:2640-2645.
2. Sata M, Suhara T, Walsh K. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to fas ligand-induced cell death. Arterioscler Thromb Vasc Biol. 2000;20:309-316.
3. Walsh K, Sata M. Negative regulation of inflammation by Fas ligand expression on the vascular endothelium. Trends Cardiovasc Med. 1999;9:34-41.
4. Aoudjit F, Vuori K. Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-FLIP and implications for anoikis. J Cell Biol. 2001;152:633-643.
5. Choy J, Granville D, Hunt D, McManus B. Endothelial cell apooptosis: biochemical characteristics and potential implications for atherosclerosis. J Mol Cell Cardiol. 2001;33:1673-1690.
6. Suhara T, Fukuo K, Osamu Y, Tsubakimoto M, Takemura Y, Kawamoto H, Yokoi T, Mogi M, Kaimoto T, Ogihara T. Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways. Hypertension. 2004;43:1208-1213.
7. Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells. Circ Res. 2004;94:370-376.
8. Sata M, Walsh K. Endothelial cell apoptosis induced by oxidized LDL is associated with the down-regulation of the cellular caspase inhibitor FLIP. J Biol Chem. 1998;273:33103-33106.
9. Sata M, Walsh K. Oxidized LDL activates Fas-mediated endothelial cell apoptosis. J Clin Invest. 1998;102:1682-1689.
10. Imanishi T, Hano T, Sawamura T, Takarada S, Nishio I. Oxidized low density lipoprotein potentiation of Fas-induced apoptosis through lectin-like oxidized-low density lipoprotein receptor-1 in human umbilical vascular endothelial cells. Circ J. 2002;66:1060-1064.
11. Dayuan L, Baichun Y, Mehta JL. Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2 and Fas. Am J Physiol. 1998;275:H568-H576.
12. Maedler K, Fontana A, Ris F, Sergeev P, Toso C, Oberholzer J, Lehmann R, Bachmann F, Tasinato A, Spinas GA, Halbari PA, Donath MY, Biancone L, Martino AD, Orlandi V, Conaldi PG, Toniolo A, Camussi G. FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication. Proc Natl Acad Sci U S A. 2002;99:8236-8241.
13. Wajant H, Pfizenmaier K, Scheurich P. Nonapoptotic Fas signaling. Cytokine Growth Factor Rev. 2003;14:53-66.
14. Biancone L, Martino AD, Orlandi V, Conaldi PG, Toniolo A, Camussi G. Development of inflammatory angiogenesis by local stimulation of Fas in vivo. J Exp Med. 1997;186:147-152.
15. Takemura Y, Fukuo K, Yasuda O, Inoue T, Inomata N, Yokoi T, Kawamoto H, Suhara T, Ogihara T. Fas signaling induces Akt activation and upregulation of endothelial nitric oxide synthase expression. Hypertension. 2004;43:880-884.
16. Wang X, DeFrances MC, Dai Y, Pediaditakis P, Johnson C, Bell A, Michalopoulos GK, Zarnegar R. A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Mol Cell. 2002;9:411-421.
17. Scaffidi C, Krammer PH, Peter ME. Isolation and analysis of components of CD95 (APO-1/Fas) death-inducing signaling complex. Methods. 1999;17:287-291.
18. Nagata S. Apoptosis by death factor. Cell. 1997;88:355-365.
19. Scaffidi C, Medema JP, Krammer PH, Peter ME, Ding S, Merkulova-Rainon T, Han ZC, Tobelem G, Biancone L, Martino AD, Orlandi V, Conaldi PG, Toniolo A, Camussi G. FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J Biol Chem. 1997;272:26953-26958.
20. Lavrik I, Krueger A, Schmitz I, Baumann S, Weyd H, Krammer PH, Kirchhoff S. The active caspase-8 heterotetramer is formed at the CD95 DISC. Cell Death Differ. 2003;10:144-145.
21. Martinon F, Holler N, Richard C, Tschopp J. Activation of a pro-apoptotic amplification loop through inhibition of NF-KB-dependent survival signals by caspase-mediated inactivation of RIP. FEBS Lett. 2000;468:134-136.
22. Kim JW, Choi E-J, Joe CO. Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene. 2000;19:4491-4499.
23. Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 1995;14:5579-5588.
24. Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. c-FLIP splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex (DISC). J Biol Chem. 2001;276:20633-20640.
25. Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol. 2001;1:50-58.
26. Peter ME. The flip side of FLIP. Biochem J. 2004;382:e1-e3.
27. Boatright K, Deis C, Denault J-B, Sutherlin D, Salvesen G. Activation of caspases-8 and -10 by FLIP (L). Biochem J. 2004;382:651-657.
28. Chan DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, Yang X. c-FLIP(L) is a dual regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J. 2002;21:3704-3714.
29. Michaeu O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, Briand C, Cruller MG. The long form of FLIP is an activator of caspase 8 at the Fas death-inducing complex. J Biol Chem. 2002;277:45162-45171.
30. Suhara T, Mano T, Oliveira BE, Walsh K. Phosphatidylinositol 3-kinase/Akl signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP). Circ Res. 2001;89:13-19.
31. Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK, Peter ME. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002;22:207-220.
32. Siegel RM, Frederiksen JK, Zacharias DA, Chan FK, Johnson M, Lynch D, Tsien RY, Lenardo MJ. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science. 2000;288:2354-2357.
33. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med. 1999;340:115-126.
34. Kataoka T, Ito M, Budd RC, Tschopp J, Nagai K. Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells. Exp Cell Res. 2002;273:256-264.
35. Bussolino F, Ziche MD, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnone L, Coffer A, Comoglio P. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol. 1992;119:629-641.
36. Ding S, Merkulova-Rainon T, Han ZC, Tobelem G, Biancone L, Martino AD, Orlandi V, Conaldi PG, Toniolo A, Camussi G. HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro. Blood. 2003;101:4816-4822.
37. Lui F, Schaphorst K, Verin A, Jacobs K, Birukova A, Day R, Bogatcheva N, Bottaro D, Garcia J. Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: potential role of glycogen synthase kinase-3beta. FASEB J. 2002;16:950-962.
38. Nakagami H, Morishita R, Yamamoto K, Taniyama Y, Aoki M, Matsumoto K, Nakamura T, Kaneda Y, Horiuchi M, Ogihara T. Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells. Hypertension. 2001;3:581-596.
39. Nakagami H, Morishita R, Yamamoto K, Taniyama Y, Aoki M, Kim S, Matsumoto K, Nakamura T, Higaki J, Ogihara T. Anti-apoptotic action of hepatocyte growth factor through mitogen-activated protein kinase on human aortic endothelial cells. J Hypertens. 2000;18:1411-1420.
40. Schulze-Bergkamen H, Brenner D, Krueger A, Suess D, Fas SC, Frey CR, Dax A, Zink D, Buchler P, Muller M, Krammer PH. Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediates apoptosis via Akt. Hepatology. 2004;39:645-654.
41. Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VR, Sherman PA, Sessa WC, Smithies O. Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1996;93:13176-13181.