Nuclear reprogramming and adult stem cell potential

Histology and Histopathology

Volumn 20, Issue 3, 2005, Pages 977-986

  Corti, S ^a   Locatelli, F ^a   Papadimitriou, D ^a   Strazzer, S ^b   Bonato, S ^a   Comi, Giacomo P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SCIENTIFIC INSTITUTE   (Italy)

Author keywords

Neurodegenerative disease; Stem cells; Therapy; Transdifferentiation

Indexed keywords

ABC TRANSPORTER; ALDEHYDE DEHYDROGENASE; BETA TUBULIN; CD133 ANTIGEN; CD45 ANTIGEN; DOPAMINE BETA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR; MYOD1 PROTEIN; NERVE CELL ADHESION MOLECULE; NEUROFILAMENT PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PERIPHERIN; PROTEIN P75; REX PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR PAX7; TYROSINE 3 MONOOXYGENASE;

AUTOLOGOUS STEM CELL TRANSPLANTATION; CELL DIFFERENTIATION; CELL FUSION; CELL ISOLATION; CELL MATURATION; CELL POPULATION; CELL RENEWAL; DEGENERATIVE DISEASE; DNA SYNTHESIS; ENZYME ACTIVITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; MUSCULAR DYSTROPHY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REVIEW; SATELLITE CELL; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; TOTIPOTENT STEM CELL;

ADULT; ANIMALS; CELL DIFFERENTIATION; CELL FUSION; CELL NUCLEUS; GENE EXPRESSION REGULATION; HUMANS; NEURODEGENERATIVE DISEASES; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 21644489345     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (85)

1. Alessandri G., Pagano S., Bez A., Benetti A., Pozzi S., Iannolo G., Baronio M., Invernici G., Caruso A., Muneretto C., Bisleri G. and Parati E. (2004). Isolation and culture of human muscle-derived stem cells able to differentiate into myogenic and neurogenic cell lineages. Lancet 364, 1872-1883.
2. Alexanian A.R. and Nomes H.O. (2001). Proliferation and regeneration of retrogradely labeled adult rat corticospinal neurons in culture. Exp. Neurol. 170, 277-282.
3. Alvarez-Dolado M., Pardal R., Garcia-Verdugo J.M., Fike J.R., Lee H.O., Pfeffer K., Lois C., Morrison S.J. and Alvarez-Buylla A. (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425, 968-973.
4. Asakura A., Seale P., Girgis-Gabardo A. and Rudnicki M.A. (2002). Myogenic specification of side population cells in skeletal muscle. J. Cell Biol. 159, 123-134.
5. Bhattacharya S., Jackson J.D., Das A.V., Thoreson W.B., Kuszynski C., James J., Joshi S. and Ahmad I. (2003). Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay. Invest. Ophthalmol. Vis. Sci. 44, 2764-2773.
6. Bjornson C.R., Rietze R.L., Reynolds B.A., Magli M.C. and Vescovi A.L. (1999). Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 283, 534-537.
7. Blau H.M., Chiu C.P. and Webster C. (1983). Cytoplasmic activation of human nuclear genes in stable heterocaryons. Cell 32, 1171-1180.
8. Brazelton T.R., Rossi F.M., Keshet G.I. and Blau H.M. (2000). From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290, 1775-1779.
9. Brewer G.J. (1999). Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture. Exp. Neurol. 159, 237-247.
10. Cai J., Cheng A., Luo Y., Lu C., Mattson M.P., Rao M.S. and Furukawa K. (2004). Membrane properties of rat embryonic multipotent neural stem cells. J. Neurochem. 88, 212-226.
11. Cao B., Zheng B., Jankowski R.J., Kimura S., Ikezawa M., Deasy B., Cummins J., Epperly M., Qu-Petersen Z. and Huard J. (2003). Muscle stem cells differentiate into haematopoietic lineages but retain myogenic potential. Nat. Cell Biol. 5, 640-646.
12. Camargo F.D., Green R., Capetenaki Y., Jackson K.A. and Goodell M.A. (2003). Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat. Med. 9, 1520-1527.
13. Chen S., Zhang Q., Wu X., Schultz P.G. and Ding S. (2004). Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc. 126, 410-411.
14. Clarke D. and Frisen J. (2001). Differentiation potential of adult stem cells. Curr. Opin. Genet. Dev. 11, 575-580.
15. Corbeil D., Roper K., Hellwig A., Tavian M., Miraglia S., Watt S.M., Simmons P.J., Peault B., Buck D.W. and Huffner W.B. (2000). The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J. Biol. Chem. 275, 5512-5520.
16. Corbel S.Y., Lee A., Yi L., Duenas J., Brazelton T.R., Blau H.M. and Rossi F.M. (2003). Contribution of hematopoietic stem cells to skeletal muscle. Nat. Med. 9, 1528-1532.
17. Corti S., Locatelli F., Donadoni C., Strazzer S., Salani S., Del Bo R., Caccialanza M., Bresolin N., Scarlato G. and Comi G.P. (2002a). Neuroectodermal and microglial differentiation of Bone Marrow cells in the mouse spinal cord and sensory ganglia. J. Neurosci. Res. 70, 721-733.
18. Corti S., Locatelli F., Strazzer S., Salani S., Del Bo R., Soligo D., Bossolasco P., Bresolin N., Scarlato G. and Comi G.P. (2002b). Modulated generation of neuronal cells from Bone Marrow by expansion and mobilization of circulating stem cells with in vivo cytokine treatment. Exp. Neurol. 177, 443-452.
19. Corti S., Locatelli F., Donadoni C., Guglieri M., Papadimitriou D., Strazzer S., Del Bo R. and Comi G.P. (2004). Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues. Brain 127, 2518-2532.
20. Couso J.P., Knust E. and Martinez Arias A. (1995). Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Curr. Biol. 5, 1437-1448.
21. Davis R.L., Weintraub H., and Lasser A.B. (1987). Expression of a single transfected eDNA converts fibrobtasts to myoblasts. Cell 51, 987-1000.
22. Del Bo R., Torrente Y., Corti S., D'Angelo M.G., Comi G.P., Fagiolari G., Salani S., Cova A., Pisati F., Moggio M., Ausenda C., Scarlato G. and Bresolin N. (2001). In vitro and in vivo tetracycline-controlled myogenic conversion of NIH-3T3 cells: evidence of programmed cell death after muscle cell transplantation. Cell Transplant. 10, 209-221.
23. Dezawa M., Kanno H., Hoshino M., Cho H., Matsumoto N., Itokazu Y., Tajima N., Yamada H., Sawada H., Ishikawa H., Mimura T., Kitada M., Suzuki Y. and Ide C. (2004). Specific induction of neuronal cells from Bone Marrow stromal cells and application for autologous transplantation. J. Clin. Invest. 113, 1701-1710.
24. Dickinson D.P., Machnicki M., Ali M.M., Zhang Z. and Sohal G.S. (2004). Ventrally emigrating neural tube (VENT) cells: a second neural tube-derived cell population. J. Anat. 205, 79-98.
25. Eggan K., Baldwin K., Tackett M., Osborne J., Gogos J., Chess A., Axel R. and Jaenisch R. (2004). Mice cloned from olfactory sensory neurons. Nature 428, 44-49.
26. Eglitis M.A. and Mezey E. (1997). Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc. Natl. Acad. Sci. USA 94, 4080-4085.
27. Fernandes K.J., McKenzie I.A., Mill P., Smith K.M., Akhavan M., Barnabe-Heider F., Biernaskie J., Junek A., Kobayashi N.R., Toma J.G., Kaplan D.R., Labosky P.A., Rafuse V., Hui C.C. and Miller F.D. (2004). A dermal niche for multipotent adult skin-derived precursor cells. Nat. Cell Biol. 6, 1082-1093.
28. Ferrari G., Cusella-De Angelis G., Colette M., Paolucci E., Stornaiuolo A., Cossu G. and Mavilio F. (1998). Muscle regeneration by Bone Marrow-derived myogenic progenitors. Science 279, 1528-1530.
29. Ferrari G., Stornaiuolo A. and Mavilio F. (2001). Failure to correct murine muscular dystrophy. Nature 411, 1014-1015.
30. Fuchs E., Tumbar T. and Guasch G. (2004). Socializing with the neighbors: stem cells and their niche. Cell 116, 769-78.
31. Fujita N. and Wade P.A. (2004). Nuclear transfer: epigenetics pays a visit. Nat. Cell Biol. 6, 920-922.
32. Gehling U.M., Ergun S., Schumacher U., Wagener C., Pantel K., Otte M., Schuch G., Schafhausen P., Mende T., Kilic N., Kluge K., Schafer B., Hossfeld D.K. and Fiedler W. (2000). In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 95, 3106-3112.
33. Goodell M.A., Brose K., Paradis G., Conner A.S. and Mulligan R.C. (1996). Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183, 1797-1806.
34. Gussoni E., Sonecka Y., Strickland C.D., Buzney E.A., Khan M.K., Flint A.F., Kunkel L.M. and Mulligan R.C. (1999). Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 401, 390-394.
35. Hess D.A., Meyerrose T.E., Wirthlin L., Craft T.P., Herrbrich P.E., Creer M.H. and Nolte J.A. (2004). Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood 104, 1648-1655.
36. Jiang Y., Jahagirdar B.N., Reinhardt R.L., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M., Du J., Aldrich S., Lisberg A., Low W.C., Largaespada D.A. and Verfaillie C.M. (2002). Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418, 41-49.
37. Kai T. and Spradling A. (2003). An empty Drosophila stem cell niche reactivates the proliferation of ectopic cells. Proc. Natl. Acad. Sci. USA 100, 4633-4688.
38. Kim M. and Morshead C.M. (2003). Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J. Neurosci. 23, 10703-10709.
39. Kogler G., Sensken S., Airey J.A., Trapp T., Muschen M., Feldhahn N., Liedtke S., Sorg R.V., Fischer J., Rosenbaum C., Greschat S., Knipper A., Bender J., Degistirici O., Gao J., Caplan A.I., Colletti E.J., Almeida-Porada G., Muller H.W., Zanjani E. and Wernet P. (2004). A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J. Exp. Med. 200, 123-135.
40. Kondo T. and Raff M. (2000). Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 289, 1754-1757.
41. Kondo T. and Raff M. (2004). Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev. 18, 2963-2972.
42. LaBarge M.A. and Blau H.M. (2002). Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury. Cell 111, 589-601.
43. Laywell E.D., Rakic P., Kukekov V.G., Holland E.C. and Steindler D.A. (2000). Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proc. Natl. Acad. Sci. USA 97, 13883-13888.
44. Lu P., Blesch A. and Tuszynski M.H. (2004). Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact?. J. Neurosci. Res. 77, 174-191.
45. Malatesta P., Hack M.A., Hartfuss E., Kettenmann H., Klinkert W., Kirchhoff F. and Gotz M. (2003). Neuronal or glial progeny: regional differences in radial glia fate. Neuron 37, 751-764.
46. Mauro A. (1961). Satellite cell of skeletal muscle fibers. J. Biophys. Biochem. Cytol. 9, 493-495.
47. McKinney-Freeman S.L., Jackson K.A., Camargo F.D., Ferrari G., Mavilio F. and Goodell M.A. (2002). Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc. Natl. Acad. Sci. USA 99, 1341-1346.
48. Merkle F.T., Tramontin A.D., Garcia-Verdugo J.M. and Alvarez-Buylla A. (2004). Radial glia give rise to adult neural stem cells in the subventricular zone. Proc. Natl. Acad. Sci. USA 101, 17528-17532.
49. Mezey E., Chandross K.J., Harta G., Maki R.A. and McKercher S.R. (2000). Turning blood into brain: cells bearing neuronal antigens generated in vivo from Bone Marrow. Science 290, 1779-1782.
50. Morshead C.M., Benveniste P., Iscove N.N. and van der Kooy D. (2002). Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat. Med. 8, 268-73.
51. Mujtaba T., Mayer-Proschel M. and Rao M.S. (1998). A common neural progenitor for the CNS and PNS. Dev. Biol. 200, 1-15.
52. Munoz-Elias G., Woodbury D. and Black I.B. (2003). Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions. Stem Cells 21, 437-448.
53. Odelberg S.J., Kollhoff A. and Keating M.T. (2000). Dedifferentiation of mammalian myotubes induced by msx1. Cell 103, 1099-1109.
54. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., Pickel J., McKay R., Nadal-Ginard B., Bodine D.M., Led A. and Anversa P. (2001). Bone Marrow cells regenerate infarcted myocardium. Nature 410, 701-705.
55. Petersen P.H., Zou K., Krauss S. and Zhong W. (2004). Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat. Neurosci. 7, 803-811.
56. Pevny L. and Rao M.S. (2003). The stem-cell menagerie. Trends Neurosci. 26, 351-359.
57. Polesskaya A., Seale P. and Rudnicki M.A. (2003). Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell 113, 841-852.
58. Qu-Petersen Z., Deasy B., Jankowski R., Ikezawa M., Cummins J., Pruchnic R., Mytinger J., Cao, B., Gates C., Wernig A. and Huard J. (2002). Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration. J. Cell Biol. 157, 851-864.
59. Schnapp E. and Tamaka E.M. (2005). Quantitative evaluation of morpholino-mediated protein knockdown of GFP, MSX1, and PAX7 during tail regeneration in Ambystoma mexicanum. Dev. Dyn. 232, 162-170.
60. Reyes M., Lund T., Lenvik T., Aguiar D., Koodie L. and Verfaillie C.M. (2001). Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 98, 2615-2625.
61. Rao M.S. (1999). Multipotent and restricted precursors in the central nervous system. Anat. Rec. 257, 137-148.
62. Sherwood R.I., Christensen J.L., Conboy I.M., Conboy M.J., Rando T.A., Weissman I.L. and Wagers A.J. (2004). Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell 119, 543-554.
63. Terada N., Hamazaki T., Oka M., Hoki M., Mastalerz D.M., Nakano Y., Meyer E.M., Morel L., Petersen B.E. and Scott E.W. (2002). Bone Marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416, 542-545.
64. Theise N.D., Badve S., Saxena R., Henegariu O., Sell S., Crawford J.M. and Krause D.S. (2000). Derivation of hepatocytes from Bone Marrow cells in mice after radiation-induced myeloablation. Hepatology 31, 235-240.
65. Toma J.G., Akhavan M., Fernandes K.J., Barnabe-Heider F., Sadikot A., Kaplan D.R. and Miller F.D. (2001). Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol. 3, 778-784.
66. Torrente Y., Tremblay J.P., Pisati F., Belicchi M., Rossi B., Sironi M., Fortunato F., El Fahime M., D'Angelo M.G., Caron N.J., Constantin G., Paulin D., Scarlato G. and Bresolin N. (2001). Intraarterial injection of muscle-derived CD34(+)Sca-1(+) stem cells restores dystrophin in mdx mice. J. Cell Biol. 152, 335-348.
67. Torrente Y., Belicchi M., Sampaolesi M., Pisati F., Meregalli M., D'Antona G., Tonlorenzi R., Porretti L., Gavina M., Mamchaoui K., Pellegrino M.A., Furling D., Mouly V., Butler-Browne G.S., Bottinelli R., Cossu G. and Bresolin N. (2004). Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle. J. Clin. Invest. 114, 182-195.
68. Tsai R.Y. and McKay R.D. (2000). Cell contact regulates fate choice by cortical stem cells. J. Neurosci. 20, 3725-3735.
69. Uchida N., Buck D.W., He D., Reitsma M.J., Masek M., Phan T.V., Tsukamoto A.S., Gage F.H. and Weissman I.L. (2000). Direct isolation of human central nervous system stem cells. Proc. Natl. Acad. Sci. USA 97, 14720-14725.
70. Vignery A. (2000). Osteoclasts and giant cells: macrophagemacrophage fusion mechanism. Int. J. Exp. Pathol. 81, 291-304.
71. Wagers A.J. and Weissman I.L. (2004). Plasticity of adult stem cells. Cell 116, 639-648.
72. Wagers A.J., Sherwood R.I., Christensen J.L. and Weissman I.L. (2002). Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 297, 2256-2259.
73. Wai P., Truong B. and Bhat K.M. (1999). Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS. Development 126, 2759-2770.
74. Wakayama T. and Yanagimachi R. (1998). Fertilisability and developmental ability of mouse oocytes with reduced amounts of cytoplasm. Zygote 6, 341-346.
75. Weigmann A., Corbeil D., Hellwig A. and Huttner W.B. (1997). Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc. Natl. Acad. Sci. USA 94, 12425-12430.
76. Weimann J.M., Johansson C.B., Trejo A. and Blau H.M. (2003). Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after Bone Marrow transplant. Nat. Cell Biol. 5, 959-966.
77. Whetton A.D. and Graham G.J. (1999). Homing and mobilization in the stem cell niche. Trends Cell Biol. 9, 233-238.
78. Wilmut I., Schnieke A.E., McWhir J., Kind A.J. and Campbell K.H. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813.
79. Woodbury D., Schwarz E.J., Prockop D.J. and Black I.B. (2000). Adult rat and human Bone Marrow stromal cells differentiate into neurons, J. Neurosci. Res. 61, 364-370.
80. Wurmser A.E., Nakashima K., Summers R.G., Toni N., D'Amour K.A., Lie D.C. and Gage F.H. (2004). Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature 430, 350-356.
81. Yin A.H., Miraglia S., Zanjani E.D., Almeida-Porada G., Ogawa M., Leary A.G., Olweus J., Kearney J. and Buck D.W. (1997) AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 90, 5002-5012.
82. Ying Q.L., Nichols J., Evans E.P. and Smith AG. (2002). Changing potency by spontaneous fusion. Nature 416, 545-548.
83. Zammit P. and Beauchamp J. (2001). The skeletal muscle satellite cell: stem cell or son of stem cell? Differentiation 68, 193-204.
84. Zhou S., Schuetz J.D., Bunting K.D., Colapietro A.M., Sampath J., Morris J.J., Lagutina I., Grosveld G.C., Osawa M., Nakauchi H. and Sorrentino B.P. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7, 1028-1034.
85. Ziller C., Dupin E., Brazeau P., Paulin D. and Le Douarin N.M. (1983). Early segregation of a neuronal precursor cell line in the neural crest as revealed by culture in a chemically defined medium. Cell 32, 627-638.