메뉴 건너뛰기




Volumn 3, Issue 5, 2004, Pages 453-457

Functional characterization of BRCA1 sequence variants using a yeast small colony phenotype assay

Author keywords

BRCA1 protein; Breast neoplasms; Saccharomyces cerevisiae

Indexed keywords

AMINO ACID; BRCA1 PROTEIN;

EID: 21644480379     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.3.5.809     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 0027433563 scopus 로고
    • Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
    • The Breast Cancer Linkage Consortium
    • Easton DF, Bishop DT, Ford D, Crockford GP. Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families. The Breast Cancer Linkage Consortium. Am J Hum Genet 1993; 52:678-701.
    • (1993) Am J Hum Genet , vol.52 , pp. 678-701
    • Easton, D.F.1    Bishop, D.T.2    Ford, D.3    Crockford, G.P.4
  • 2
    • 0028330276 scopus 로고
    • Risks of cancer in BRCA1-mutation carriers
    • Breast Cancer Linkage Consortium
    • Ford D, Easton DF, Bishop DT, Narod SA, Goldgar DE. Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Lancet 1994; 343:692-5.
    • (1994) Lancet , vol.343 , pp. 692-695
    • Ford, D.1    Easton, D.F.2    Bishop, D.T.3    Narod, S.A.4    Goldgar, D.E.5
  • 3
    • 0028843102 scopus 로고
    • Breast and ovarian cancer incidence in BRCA1-mutation carriers
    • Breast Cancer Linkage Consortium
    • Easton DF, Ford D, Bishop DT. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Am J Hum Genet 1995; 56:265-71.
    • (1995) Am J Hum Genet , vol.56 , pp. 265-271
    • Easton, D.F.1    Ford, D.2    Bishop, D.T.3
  • 5
    • 0027960790 scopus 로고
    • Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds
    • Neuhausen SL, Marshall CJ. Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds. Cancer Res 1994; 54:6069-72.
    • (1994) Cancer Res , vol.54 , pp. 6069-6072
    • Neuhausen, S.L.1    Marshall, C.J.2
  • 6
    • 0026935108 scopus 로고
    • Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome
    • Smith SA, Easton DF, Evans DG, Ponder BA. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nat Genet 1992; 2:128-31.
    • (1992) Nat Genet , vol.2 , pp. 128-131
    • Smith, S.A.1    Easton, D.F.2    Evans, D.G.3    Ponder, B.A.4
  • 8
    • 0030759895 scopus 로고    scopus 로고
    • Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1
    • Somasundaram K, Zhang H, Zeng YX, Houvras Y, Peng Y, Zhang H, et al. Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1. Nature 1997; 389:187-90.
    • (1997) Nature , vol.389 , pp. 187-190
    • Somasundaram, K.1    Zhang, H.2    Zeng, Y.X.3    Houvras, Y.4    Peng, Y.5    Zhang, H.6
  • 10
    • 0029980129 scopus 로고    scopus 로고
    • Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core
    • Couch FJ, Weber BL. Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core. Hum Mutat 1996; 8:8-18.
    • (1996) Hum Mutat , vol.8 , pp. 8-18
    • Couch, F.J.1    Weber, B.L.2
  • 11
    • 0028034348 scopus 로고
    • Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families
    • Friedman LS, Ostermeyer EA, Szabo CI, Dowd P, Lynch ED, Rowell SE, et al. Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families. Nat Genet 1994; 8:399-404.
    • (1994) Nat Genet , vol.8 , pp. 399-404
    • Friedman, L.S.1    Ostermeyer, E.A.2    Szabo, C.I.3    Dowd, P.4    Lynch, E.D.5    Rowell, S.E.6
  • 12
    • 0034913641 scopus 로고    scopus 로고
    • BRCA1, BRCA2 and breast cancer: A concise clinical review
    • Carter RF. BRCA1, BRCA2 and breast cancer: A concise clinical review. Clin Invest Med 2001; 24:147-57.
    • (2001) Clin Invest Med , vol.24 , pp. 147-157
    • Carter, R.F.1
  • 13
    • 0037190607 scopus 로고    scopus 로고
    • BRCA1: Mechanisms of inactivation and implications for management of patients
    • Kennedy RD, Quinn JE, Johnston PG, Harkin DP. BRCA1: Mechanisms of inactivation and implications for management of patients. Lancet 2002; 360:1007-14.
    • (2002) Lancet , vol.360 , pp. 1007-1014
    • Kennedy, R.D.1    Quinn, J.E.2    Johnston, P.G.3    Harkin, D.P.4
  • 14
    • 0342940785 scopus 로고    scopus 로고
    • Pathology of familial breast cancer: Differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases
    • Breast Cancer Linkage Consortium
    • Pathology of familial breast cancer: Differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Breast Cancer Linkage Consortium. Lancet 1997; 349:1505-10.
    • (1997) Lancet , vol.349 , pp. 1505-1510
  • 15
    • 13344262707 scopus 로고    scopus 로고
    • Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage
    • Marcus JN, Watson P, Page DL, Narod SA, Lenoir GM, Tonin P, et al. Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer 1996; 77:697-709.
    • (1996) Cancer , vol.77 , pp. 697-709
    • Marcus, J.N.1    Watson, P.2    Page, D.L.3    Narod, S.A.4    Lenoir, G.M.5    Tonin, P.6
  • 18
    • 0037014776 scopus 로고    scopus 로고
    • Gene expression profiling of hereditary and sporadic ovarian cancers reveals unique BRCA1 and BRCA2 signatures
    • Hedenfalk IA. Gene expression profiling of hereditary and sporadic ovarian cancers reveals unique BRCA1 and BRCA2 signatures. J Natl Cancer Inst 2002; 94:960-1.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 960-961
    • Hedenfalk, I.A.1
  • 19
    • 0034306456 scopus 로고    scopus 로고
    • BRCA1: Exploring the links to transcription
    • Monteiro AN. BRCA1: Exploring the links to transcription. Trends Biochem Sci 2000; 25:469-74.
    • (2000) Trends Biochem Sci , vol.25 , pp. 469-474
    • Monteiro, A.N.1
  • 20
    • 0035928799 scopus 로고    scopus 로고
    • New complexities for BRCA1 and BRCA2
    • Kerr P, Ashworth A. New complexities for BRCA1 and BRCA2. Curr Biol 2001; 11:R668-76.
    • (2001) Curr Biol , vol.11
    • Kerr, P.1    Ashworth, A.2
  • 21
    • 0036247531 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 in hereditary breast cancer
    • Scully R, Puget N. BRCA1 and BRCA2 in hereditary breast cancer. Biochimie 2002; 84:95-102.
    • (2002) Biochimie , vol.84 , pp. 95-102
    • Scully, R.1    Puget, N.2
  • 22
    • 0034753160 scopus 로고    scopus 로고
    • Functions of BRCA1 and BRCA2 in the biological response to DNA damage
    • Venkitaraman AR. Functions of BRCA1 and BRCA2 in the biological response to DNA damage. J Cell Sci 2001; 114:3591-8.
    • (2001) J Cell Sci , vol.114 , pp. 3591-3598
    • Venkitaraman, A.R.1
  • 23
    • 85039388162 scopus 로고    scopus 로고
    • Direct submission
    • Accession number: AAG43492
    • Walter NAR, Messier W. Direct submission. Genbank 1999; Accession number: AAG43492.
    • (1999) Genbank
    • Walter, N.A.R.1    Messier, W.2
  • 25
    • 0032810852 scopus 로고    scopus 로고
    • Sequence analysis of the rat Brca1 homolog and its promoter region
    • Bennett LM, Brownlee HA, Hagavik S, Wiseman RW. Sequence analysis of the rat Brca1 homolog and its promoter region. Mamm Genome 1999; 10:19-25.
    • (1999) Mamm Genome , vol.10 , pp. 19-25
    • Bennett, L.M.1    Brownlee, H.A.2    Hagavik, S.3    Wiseman, R.W.4
  • 26
    • 85039370017 scopus 로고    scopus 로고
    • Bos taurus breast and ovarian cancer susceptibility protein (BRCA1) mRNA
    • Accession number: NP_848668
    • Krum SA, Lane TF. Bos taurus breast and ovarian cancer susceptibility protein (BRCA1) mRNA. Genbank 2002;Accession number: NP_848668.
    • (2002) Genbank
    • Krum, S.A.1    Lane, T.F.2
  • 27
    • 0035913163 scopus 로고    scopus 로고
    • Nine novel conserved motifs in BRCA1 identified by the chicken orthologue
    • Orelli BJ, Logsdon Jr JM, Bishop DK. Nine novel conserved motifs in BRCA1 identified by the chicken orthologue. Oncogene 2001; 20:4433-8.
    • (2001) Oncogene , vol.20 , pp. 4433-4438
    • Orelli, B.J.1    Logsdon Jr., J.M.2    Bishop, D.K.3
  • 28
    • 0035833994 scopus 로고    scopus 로고
    • Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development
    • USA
    • Joukov V, Chen J, Fox EA, Green JB, Livingston DM. Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development. Proc Natl Acad Sci USA 2001; 98:12078-83.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 12078-12083
    • Joukov, V.1    Chen, J.2    Fox, E.A.3    Green, J.B.4    Livingston, D.M.5
  • 31
    • 0034809456 scopus 로고    scopus 로고
    • Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
    • Williams RS, Green R, Glover JN. Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1. Nat Struct Biol 2001; 8:838-42.
    • (2001) Nat Struct Biol , vol.8 , pp. 838-842
    • Williams, R.S.1    Green, R.2    Glover, J.N.3
  • 33
    • 0037462647 scopus 로고    scopus 로고
    • Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
    • Williams RS, Glover JN. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J Biol Chem 2003; 278:2630-5.
    • (2003) J Biol Chem , vol.278 , pp. 2630-2635
    • Williams, R.S.1    Glover, J.N.2
  • 36
    • 0035842893 scopus 로고    scopus 로고
    • BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
    • Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001; 155:911-21.
    • (2001) J Cell Biol , vol.155 , pp. 911-921
    • Ye, Q.1    Hu, Y.F.2    Zhong, H.3    Nye, A.C.4    Belmont, A.S.5    Li, R.6
  • 37
    • 0029830051 scopus 로고    scopus 로고
    • Transcriptional activation by BRCA1
    • Chapman MS, Verma IM. Transcriptional activation by BRCA1. Nature 1996; 382:678-9.
    • (1996) Nature , vol.382 , pp. 678-679
    • Chapman, M.S.1    Verma, I.M.2
  • 38
    • 0034194328 scopus 로고    scopus 로고
    • Functional assay for BRCA1: Mutagenesis of the COOH-terminal region reveals critical residues for transcription activation
    • Hayes F, Cayanan C, Barilla D, Monteiro AN. Functional assay for BRCA1: Mutagenesis of the COOH-terminal region reveals critical residues for transcription activation. Cancer Res 2000; 60:2411-8.
    • (2000) Cancer Res , vol.60 , pp. 2411-2418
    • Hayes, F.1    Cayanan, C.2    Barilla, D.3    Monteiro, A.N.4
  • 39
    • 0030474170 scopus 로고    scopus 로고
    • Evidence for a transcriptional activation function of BRCA1 C-terminal region
    • USA
    • Monteiro AN, August A, Hanafusa H. Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 1996; 93:13595-9.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 13595-13599
    • Monteiro, A.N.1    August, A.2    Hanafusa, H.3
  • 40
    • 0030850687 scopus 로고    scopus 로고
    • Common BRCA1 variants and transcriptional activation
    • Monteiro AN, August A, Hanafusa H. Common BRCA1 variants and transcriptional activation. Am J Hum Genet 1997; 61:761-2.
    • (1997) Am J Hum Genet , vol.61 , pp. 761-762
    • Monteiro, A.N.1    August, A.2    Hanafusa, H.3
  • 43
    • 0001221269 scopus 로고    scopus 로고
    • Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
    • Kleiman FE, Manley JL. Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50. Science 1999; 285:1576-9.
    • (1999) Science , vol.285 , pp. 1576-1579
    • Kleiman, F.E.1    Manley, J.L.2
  • 44
    • 0034704096 scopus 로고    scopus 로고
    • A functional comparison of BRCA1 C-terminal domains in transcription activation and chromatin remodeling
    • Miyake T, Hu YF, Yu DS, Li R. A functional comparison of BRCA1 C-terminal domains in transcription activation and chromatin remodeling. J Biol Chem 2000; 275:40169-73.
    • (2000) J Biol Chem , vol.275 , pp. 40169-40173
    • Miyake, T.1    Hu, Y.F.2    Yu, D.S.3    Li, R.4
  • 45
    • 0031946411 scopus 로고    scopus 로고
    • Yeast-based assays for detection and characterization of mutations in BRCA1
    • Monteiro AN, Humphrey JS. Yeast-based assays for detection and characterization of mutations in BRCA1. Breast Disease 1998; 10:61-70.
    • (1998) Breast Disease , vol.10 , pp. 61-70
    • Monteiro, A.N.1    Humphrey, J.S.2
  • 46
    • 0000714256 scopus 로고
    • Mutagenesis and synthesis of novel recombinant genes using PCR
    • Dieffenbach CW, Dveksler GS, eds. PCR Primer: Plainview, NY: Cold Spring Harbor Press
    • Vallejo AN, Pogulis RJ, Pease LR. Mutagenesis and synthesis of novel recombinant genes using PCR. In: Dieffenbach CW, Dveksler GS, eds. PCR Primer: A Laboratory Manual. Plainview, NY: Cold Spring Harbor Press, 1995; 603-612.
    • (1995) A Laboratory Manual , pp. 603-612
    • Vallejo, A.N.1    Pogulis, R.J.2    Pease, L.R.3
  • 47
    • 0029099409 scopus 로고
    • Ras-Raf interaction: Two-hybrid analysis
    • Vojtek AB, Hollenberg SM. Ras-Raf interaction: Two-hybrid analysis. Methods Enzymol 1995; 255:331-42.
    • (1995) Methods Enzymol , vol.255 , pp. 331-342
    • Vojtek, A.B.1    Hollenberg, S.M.2
  • 48
    • 0026599048 scopus 로고
    • One-step method for yeast transformation
    • Chen CF, Yang B. One-step method for yeast transformation. Curr. Genet 1992; 21:83-84.
    • (1992) Curr. Genet , vol.21 , pp. 83-84
    • Chen, C.F.1    Yang, B.2
  • 49
    • 2542543477 scopus 로고    scopus 로고
    • Structure-based assessment of missense mutations in human BRCA1: Implications for breast and ovarian cancer predisposition
    • In press
    • Mirkovic N, Marti-Renom MA, Weber BL, et al. Structure-based assessment of missense mutations in human BRCA1: Implications for breast and ovarian cancer predisposition. Cancer Res 2004; In press.
    • (2004) Cancer Res
    • Mirkovic, N.1    Marti-Renom, M.A.2    Weber, B.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.