Possible involvement of protein kinase C activation in differentiation of human umbilical vein endothelium-derived cellinto smooth muscle-like cell

Biology of the Cell

Volumn 96, Issue 7, 2004, Pages 499-

  Ishisaki, Akira ^a,b   Tsunobuchi, Hironaka ^a   Nakajima, Keiichi ^a   Imamura, Toru ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Endothelium derived cell; Fibroblast growth factor; Protein kinase C; Smooth muscle like cell

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; BISINDOLYLMALEIMIDE I; CARBAZOLE DERIVATIVE; CARCINOGEN; ENZYME INHIBITOR; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

CARBAZOLES; CARCINOGENS; CELL DIFFERENTIATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INDOLES; MALEIMIDES; MYOCYTES, SMOOTH MUSCLE; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; UMBILICAL VEINS;

EID: 21644433901     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1016/j.biolcel.2004.04.012     Document Type: Article

References (54)

1. Arciniegas, E., Sutton, A.B., Allen, T.D., Schor, A.M., 1992. Transforming growth factor beta 1 promotes the differentiation of endothelial cells into smooth muscle cells in vitro. J. Cell Sci. 103, 521-529.
2. Arciniegas, E., Ponce, L., Hartt,Y., Graterol, A., Carlini, R.G., 2000. Intimal thickening involves transdifferentiation of embryonic endothelial cells. Anat. Rec. 258, 47-57.
3. Assender, J.W., Kontny, E., Fredholm, B.B., 1994. Expression of pretein kinase C isoforms in smooth muscle cells in various states of differentiation. FEBS Lett. 342, 76-80.
4. Braz, J.C., Bueno, O.F., De Windt, L.J., Molkentin, J.D., 2002. PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2). J. Cell Biol. 156, 905-919.
5. Brodie, C., Kuperstein, I., Acs, P., Blumberg, P.M., 1998. Differential role of specific PKC isoforms in the proliferation of glial cells and the expression of the astrocytic markers GFAP and glutamine synthetase. Mol. Brain Res. 56, 108-117.
6. Carmeliet, P., 2000. Mechanisms of angiogenesis and arteriogenesis. Nature Med. 6, 389-395.
7. Chaturvedi, K., Sarkar, D.K., 2003. Involvement of PKC-dependent MAP kinase p44/42 signaling pathway for cross-talk between estradiol and TGF-beta3 in increasing bFGF in folliculostellate cells. Endocrinology Nov. 6 [Epub ahead of print].
8. Chen, C.C., 1993. Protein kinase C alpha, delta, epsilon and zeta in C6 glioma cells. TPA induces translocation and down-regulation of conventional and new PKC isoforms but not atypical PKC zeta. FEBS Lett. 332, 169-173.
9. Chen, Y., Wu, Q., Song, S.Y., Su, W.J., 2002. Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells. World J. Gastroenterol. 8, 1014-1018.
10. Cox, C.M., Poole, T.J., 2000. Angioblast differentiation is influenced by the local environment: FGF-2 induces angioblasts and patterns vessel formation in the quail embryo. Dev. Dyn. 218, 371-382.
11. DeRuitar, M.C., Poelmann, R.E., VanMunsteren, J.C., Mironov, V., Markwald, R.R., Gittenberger-de Groot, A.C., 1997. Embryonic endothelial cells transdifferentiate into mesenchymal cells expressing smooth muscle actins in vivo and in vitro. Circ. Res. 80, 444-451.
12. Frid, M.G., Kale,V.A., Stenmark, K.R., 2002. Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis. Circ. Res. 90, 1189-1196.
13. Fukumoto, S., Nishizawa, Y., Hosoi, M., Koyama, H., Yamakawa, K., Ohno, S., Morii, H., 1997. Protein kinase C d inhbits the proliferation of vascular smooth muscle cells by suppressing G1 cyclin expression. J. Biol. Chem. 272, 13816-13822.
14. Haller, H., Lindschau, C., Quass, P., Distler, A., Luft, F.C., 1995. Differentiation of vascular smooth muscle cells and regulation of protein kinase C-a. Circ. Res. 76, 21-29.
15. Hellstrom, M., Kalen, M., Lindahl, P., Abramsson, A., Betsholtz, C., 1999. Roles of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 126, 3047-3055.
16. Hirschi, K.K., Rohovsky, S.A., D'Amore, P.A., 1998. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J. Cell Biol. 141, 805-814.
17. Hug, H., Sarre, T.F., 1993. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291, 329-343.
18. Imamura, T., Mitsui,Y., 1987. Heparan sulfate and heparin as a potentiator or a suppressor of growth of normal and transformed vascular endothelial cells. Exp. Cell Res. 172, 92-100.
19. Imamura, T., Engleka, K., Zhan, X., Tokita, Y., Frough, R., Roeder, D., Jackson, A., Maier, J.A., Hla, T., Maciag, T., 1990. Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science 249, 1567-1570.
20. Ishisaki, A., Hayashi, H., Li, A.-J., Imamura, T., 2003. Human umbilical vein endothelium-derived cells retain potential to differentiate into smooth muscle-like cells. J. Biol. Chem. 278, 1303-1309.
21. Isner, J.M., Asahara, T., 1999. Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization. J. Clin. Invest. 103, 1231-1236.
22. Ito, Y., Mishra, N.C., Yoshida, K., Kharbanda, S., Saxena, S., Kufe, D., 2001. Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells. Cell Death Differ. 8, 794-800.
23. Jaken, S., 1996. Protein kinase isoenzymes and substrates. Curr. Opin. Cell Biol. 8, 168-173.
24. Keranen, L.M., Dutil, E.M., Newton, A.C., 1995. Protein kinase C is regulated in vivo by three functionally distinct phosphorylations. Curr. Biol. 5, 1394-1403.
25. Kishimoto, A., Mikawa, K., Hashimoto, K., Yasuda, I., Tanaka, S.-I., Tominaga, M., Kuroda, T., Nihsizuka, Y., 1989. Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain). J. Biol. Chem. 264, 4088-4092.
26. Littele, D., Said, J.W., Siegel, R.J., Fealy, M., Fishbein, M.C., 1986. Endothelial cell markers in vascular neoplasms: an immunohistochemical study comparing factor VIII-related antigen, blood group specific antigens, 6-keto-PGF1 alpha, and Ulex europaeus 1 lectin. J. Pathol. 149, 89-95.
27. Mauro, A., Ciccarelli, C., De Casaris, P., Scoglio, A., Bouchè, M., Molinaro, M., Aquino, A., Zani, B.M., 2002. PKCα-mediated ERK, JNK and p38 activation regulates the myogenic program in human rhabdomysarcoma cells. J. Cell Sci. 115, 3587-3599.
28. McComb, R.D., Jones, T.R., Pizzo, S.V., Bigner, D.D., 1982. Localization of factor VIII/von Willebrand factor and glial fibrillary acidic protein in the hemangioblastoma: implications for stromal cell histogenesis. Acta Neuropathol (Berl.) 56, 207-213.
29. Miao, D., Tong, X.K., Chan, G.K., Panda, D., McPherson, P.S., Goltzman, D., 2001. Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/ mitogen-activated protein kinase signaling pathway. J. Biol. Chem. 276, 32202-32213.
30. Motwani, J.G., Topol, E.J., 1998. Aortocoronary sapheous vein graft disease: pathogenesis, predisposition, and prevention. Circulation 97, 916-931.
31. Nakajima, Y., Mironov, V., Yamagishi, T., Nakamura, H., Markward, R.R., 1997. Expression of smooth muscle alpha-actin in mesenchymal cells during formation of avian endocardial cushion tissue: a role for transforming growth factor 3. Dev. Dyn. 209, 296-309.
32. Nishizuka, Y., 1986. Studies and perspectives of protein kinase C. Science 233, 305-312.
33. Nishizuka, Y., 1988. The molecular heterogeneity of protein kinase C and its implication for cellular regulation. Nature 334, 661-665.
34. O'Brien, J.E., Shi, Y., Fard, A., Bauer, T., Zaleuski, A., Mannion, J.D., 1997. Wound healing around and within saphenous vein bypass grafts. J. Thorac. Cardiovasc. Surg. 114, 38-45.
35. Ohno, S., Akita, Y., Hata, A., Osada, S., Kubo, K., Kohno, Y., Akimoto, K., Mizuno, K., Saido, T., Kuroki, T., Suzuki, K., 1991. Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and novel nPKC. Adv. Enzyme Regul. 31, 287-303.
36. Olivier, A.R., Parker, P.J., 1992. Identification of multiple PKC isoforms in Swiss 3T3 cells: differential down-regulation by phorbol ester. J. Cell. Physiol. 152, 240-244.
37. Ozawa, K., Seo, M., Imamura, T., 1997. A quantitative method for evaluation of FGF family and FGF family gene expression by RT-PCR. Brain Res. Protocol 1, 211-216.
38. Poole, T.J., Finkelstein, E.B., Cox, C.M., 2001. The role of FGF and VEGF in angioblast induction andmigration during vascular development. Dev. Dyn. 220, 1-17.
39. Powers, C.J., McLesky, S.W., Wellstein, A., 2000. Fibroblast growth factors, their receptors and signaling. Endocr. Relat. Cancer 7, 165-197.
40. Raffi, S., 2000. Circulating endothelial precursors: mystery, reality, and promise. J. Clin. Invest. 105, 17-19.
41. Ross, R., Glomset, J.A., 1973. Atherosclerosis and the arterial smooth muscle. Science 180, 1332-1339.
42. Ross, R., 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.
43. Ross, R., 1999. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340, 115-126.
44. Runyan, C.E., Schnaper, H.W., Poncelet, A.C., 2003. Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells. Am. J. Physiol. Renal Physiol. 285, F413-422.
45. Sharkey, N.A., Leach, K.L., Blumberg, P.M., 1984. Competitive inhibition by diacylglycerol of specific phorbol ester binding. Proc. Natl. Acad. Sci. USA 81, 607-610.
46. Sobue, K., Hayashi, K., Nishida, W., 1999. Expressional regulation of smooth muscle cell-specific genes in association with phenotypic modulation. Mol. Cell. Biochem. 190, 105-118.
47. Strasser, P., Gimona, M., Moessler, H., Herzog, M., Small, J.B., 1993. Mammalian calponin. Identification and expression of genetic variants. FEBS Lett. 330, 13-18.
48. Takahashi, K., Nadal-Ginard, B., 1991. Molecular cloning and sequence analysis of smooth muscle calponin. J. Biol. Chem. 266, 13284-13288.
49. Wang, S., Desai, D., Wright, G., Niles, R.M., Wright, G.L., 1997. Effects of protein kinase Ca overexpression on A7r5 smooth muscle cell proliferation and differentiation. Exp. Cell. Res. 236, 117-126.
50. Way, K.J., Chou, E., King, G.L., 2000. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol. Sci. 21, 181-187.
51. Weissberg, P.L., Cary, N.R., Shanahan, C.M., 1995. Gene expression and vascular smooth muscle cell phenotype. Blood Press. Supple. 2, 68-73.
52. Yakymovych, I., ten Dijke, P., Heldin, C.H., Souchelnytskyi, S., 2001. Regulation of smad signaling by protein kinase C. FASEB J. 15, 553-555.
53. Yamashita, J., Itoh, H., Hirashima, M., Ogawa, M., Nishikawa, S., Yurugi, T., Naito, M., Nakao, K., Nishikawa, S., 2000. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 408, 92-96.
54. Young, S., Parker, P.J., Ullrich, A., Stabel, S., 1987. Down-regulation of protein kinase C is due to an increased rate of degradation. J. Biol. Chem. 244, 775-779.