메뉴 건너뛰기




Volumn 56, Issue 1-2, 1998, Pages 108-117

Differential role of specific PKC isoforms in the proliferation of glial cells and the expression of the astrocytic markers GFAP and glutamine synthetase

Author keywords

Astrocytic differentiation; GFAP; Glutamine synthetase; Proliferation; Protein kinase C (PKC)

Indexed keywords

CELL MARKER; GLUTAMATE AMMONIA LIGASE; ISOENZYME; PROTEIN KINASE C;

EID: 0007543134     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00035-7     Document Type: Article
Times cited : (46)

References (51)
  • 1
    • 0028054332 scopus 로고
    • Developmental expression of protein kinase C isozymes in oligodendrocytes and their differential modulation by 4-beta-phorbol-12,13-butyrate
    • Asorta K., Macklin W. Developmental expression of protein kinase C isozymes in oligodendrocytes and their differential modulation by 4-beta-phorbol-12,13-butyrate. J. Neurosci. Res. 39:1994;273-289.
    • (1994) J. Neurosci. Res. , vol.39 , pp. 273-289
    • Asorta, K.1    MacKlin, W.2
  • 2
    • 0029064245 scopus 로고
    • Protein kinase C isoform alpha overexpression in C6 glioma cells and its role in cell proliferation
    • Baltuch G.H., Dooley N.P., Rostworowski K.M., Villemure J.-G., Yong V.W. Protein kinase C isoform alpha overexpression in C6 glioma cells and its role in cell proliferation. J. Neurooncol. 24:1995;241-250.
    • (1995) J. Neurooncol. , vol.24 , pp. 241-250
    • Baltuch, G.H.1    Dooley, N.P.2    Rostworowski, K.M.3    Villemure, J.-G.4    Yong, V.W.5
  • 3
    • 0024348376 scopus 로고
    • Astrocyte morphology altered by 1-(5-isoquinolinylsulfonyl)2-methyl piperazine (H-7) and other protein kinase inhibitors
    • Bedoy C.A., Mobley P.L. Astrocyte morphology altered by 1-(5-isoquinolinylsulfonyl)2-methyl piperazine (H-7) and other protein kinase inhibitors. Brain Res. 490:1989;243-254.
    • (1989) Brain Res. , vol.490 , pp. 243-254
    • Bedoy, C.A.1    Mobley, P.L.2
  • 5
    • 0024548968 scopus 로고
    • Role of protein kinase C in glial cell proliferation
    • Bhat N.R. Role of protein kinase C in glial cell proliferation. J. Neurosci. Res. 22:1989;20-27.
    • (1989) J. Neurosci. Res. , vol.22 , pp. 20-27
    • Bhat, N.R.1
  • 6
    • 0029555676 scopus 로고
    • Signal transduction mechanisms in glial cells
    • Bhat N.R. Signal transduction mechanisms in glial cells. Dev. Neurosci. 17:1995;267-284.
    • (1995) Dev. Neurosci. , vol.17 , pp. 267-284
    • Bhat, N.R.1
  • 7
    • 0028815491 scopus 로고
    • Two closely related isoforms of protein kinase C produce reciprocal effects on the growth of rat fibroblasts. Possible molecular mechanisms
    • Borner C., Ueffing M., Jaken S., Parker P.J., Weinstein I.B. Two closely related isoforms of protein kinase C produce reciprocal effects on the growth of rat fibroblasts. Possible molecular mechanisms. J. Biol. Chem. 270:1995;78-86.
    • (1995) J. Biol. Chem. , vol.270 , pp. 78-86
    • Borner, C.1    Ueffing, M.2    Jaken, S.3    Parker, P.J.4    Weinstein, I.B.5
  • 8
    • 0031571712 scopus 로고    scopus 로고
    • Functional effects of overexpression of protein kinase C-alpha, -beta, -delta, -epsilon and -eta in the mast cell line RBL-2H3
    • Chang E.U., Szallasi Z., Acs P., Raizada V., Wolfe P.C., Fewtrell C., Blumberg P.M., Rivera J. Functional effects of overexpression of protein kinase C-alpha, -beta, -delta, -epsilon and -eta in the mast cell line RBL-2H3. J. Immunol. 159:1997;2624-2632.
    • (1997) J. Immunol. , vol.159 , pp. 2624-2632
    • Chang, E.U.1    Szallasi, Z.2    Acs, P.3    Raizada, V.4    Wolfe, P.C.5    Fewtrell, C.6    Blumberg, P.M.7    Rivera, J.8
  • 9
    • 0029073263 scopus 로고
    • Role of protein kinase C subtypes alpha and delta in the regulation of bradykinin-stimulated phosphoinositide breakdown in astrocytes
    • Chen C.C., Chang J., Chen W.C. Role of protein kinase C subtypes alpha and delta in the regulation of bradykinin-stimulated phosphoinositide breakdown in astrocytes. Mol. Pharmacol. 39:1995;39-47.
    • (1995) Mol. Pharmacol. , vol.39 , pp. 39-47
    • Chen, C.C.1    Chang, J.2    Chen, W.C.3
  • 10
    • 0028247034 scopus 로고
    • Immunohistochemical localization of protein kinase C delta during postnatal development of the cerebellum
    • Chen S., Hillman D.E. Immunohistochemical localization of protein kinase C delta during postnatal development of the cerebellum. Dev. Brain Res. 80:1994;19-25.
    • (1994) Dev. Brain Res. , vol.80 , pp. 19-25
    • Chen, S.1    Hillman, D.E.2
  • 11
    • 0019720690 scopus 로고
    • The cytoskeleton of primary astrocytes in culture contain actin, glial fibrillary acidic protein, and the fibroblast-type filament protein, vimentin
    • Chiu F.C., Norton W.T., Fields K.L. The cytoskeleton of primary astrocytes in culture contain actin, glial fibrillary acidic protein, and the fibroblast-type filament protein, vimentin. J. Neurochem. 37:1981;147-155.
    • (1981) J. Neurochem. , vol.37 , pp. 147-155
    • Chiu, F.C.1    Norton, W.T.2    Fields, K.L.3
  • 13
    • 0029032442 scopus 로고
    • Adaptation of C6 glioma cells to serum-free conditions leads to the expression of a mixed astrocyte-oligodendrocyte phenotype and increased production of neurite-promoting activity
    • Coyle D.E. Adaptation of C6 glioma cells to serum-free conditions leads to the expression of a mixed astrocyte-oligodendrocyte phenotype and increased production of neurite-promoting activity. J. Neurosci. Res. 41:1995;374-385.
    • (1995) J. Neurosci. Res. , vol.41 , pp. 374-385
    • Coyle, D.E.1
  • 15
    • 0023858963 scopus 로고
    • Glutamine synthetase: A marker of an astroglial subpopulation in primary cultures of defined brain areas
    • Fages C., Khelil M., Rolland A.M., Bridoux A.M., Tardy M. Glutamine synthetase: a marker of an astroglial subpopulation in primary cultures of defined brain areas. Dev. Neurosci. 10:1988;47-56.
    • (1988) Dev. Neurosci. , vol.10 , pp. 47-56
    • Fages, C.1    Khelil, M.2    Rolland, A.M.3    Bridoux, A.M.4    Tardy, M.5
  • 16
    • 0030608443 scopus 로고    scopus 로고
    • Hormonal and non-hormonal regulation of glutamine synthetase in the developing neural retina
    • Gorovits R., Yakir A., Fox L.E., Vardimon L. Hormonal and non-hormonal regulation of glutamine synthetase in the developing neural retina. Mol. Brain Res. 43:1996;321-329.
    • (1996) Mol. Brain Res. , vol.43 , pp. 321-329
    • Gorovits, R.1    Yakir, A.2    Fox, L.E.3    Vardimon, L.4
  • 17
    • 0029970696 scopus 로고    scopus 로고
    • Protein kinase C alpha expression in required for heparin inhibition of rat smooth muscle cell proliferation in vitro and in vivo
    • Herbert J.M., Clowes M., Lea H.J., Pascal M., Clowes A.W. Protein kinase C alpha expression in required for heparin inhibition of rat smooth muscle cell proliferation in vitro and in vivo. J. Biol. Chem. 271:1996;25928-25935.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25928-25935
    • Herbert, J.M.1    Clowes, M.2    Lea, H.J.3    Pascal, M.4    Clowes, A.W.5
  • 18
    • 0022544533 scopus 로고
    • Protein kinase C-activating tumor promoters enhance the differentiation of astrocytes in aggregating fetal brain cell cultures
    • Honegger P. Protein kinase C-activating tumor promoters enhance the differentiation of astrocytes in aggregating fetal brain cell cultures. J. Neurochem. 46:1986;1561-1566.
    • (1986) J. Neurochem. , vol.46 , pp. 1561-1566
    • Honegger, P.1
  • 19
    • 0028945649 scopus 로고
    • Effects of dibutyryl cyclic AMP and dexamethasone and glutamine synthetase gene expression in rat astrocytes in culture
    • Jackson M.J., Zielke H.R., Max S.R. Effects of dibutyryl cyclic AMP and dexamethasone and glutamine synthetase gene expression in rat astrocytes in culture. Neurochem. Res. 20:1995;201-207.
    • (1995) Neurochem. Res. , vol.20 , pp. 201-207
    • Jackson, M.J.1    Zielke, H.R.2    Max, S.R.3
  • 20
    • 0029965696 scopus 로고    scopus 로고
    • Protein kinase isozymes and substrates
    • Jaken S. Protein kinase isozymes and substrates. Curr. Opin. Cell Biol. 8:1996;18-173.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 18-173
    • Jaken, S.1
  • 22
    • 0027297104 scopus 로고
    • Characterization of ligands and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isoenzymes
    • Kazanietz M.G., Areces L.B., Bahador A., Mischak H., Goodnight J., Mushinski J.F., Blumberg P.M. Characterization of ligands and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isoenzymes. Mol. Pharmacol. 44:1993;298-307.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 298-307
    • Kazanietz, M.G.1    Areces, L.B.2    Bahador, A.3    Mischak, H.4    Goodnight, J.5    Mushinski, J.F.6    Blumberg, P.M.7
  • 23
    • 0029163302 scopus 로고
    • Staurosporine induces astrocytic phenotypes and differential expression of specific PKC isoforms
    • Kronfeld I., Tsukerman A., Kazimirsky G., Brodie C. Staurosporine induces astrocytic phenotypes and differential expression of specific PKC isoforms. J. Neurochem. 65:1995;1505-1514.
    • (1995) J. Neurochem. , vol.65 , pp. 1505-1514
    • Kronfeld, I.1    Tsukerman, A.2    Kazimirsky, G.3    Brodie, C.4
  • 24
    • 0027017778 scopus 로고
    • Comparative biochemical, morphological and immunohistochemical studies between C6 glial cells of early and late passages and advanced passages of glial cells derived from aged mouse cerebral hemispheres
    • Lee K., Kentroti S., Billie H., Bruce C., Vernadakis A. Comparative biochemical, morphological and immunohistochemical studies between C6 glial cells of early and late passages and advanced passages of glial cells derived from aged mouse cerebral hemispheres. Glia. 6:1992;245-257.
    • (1992) Glia , vol.6 , pp. 245-257
    • Lee, K.1    Kentroti, S.2    Billie, H.3    Bruce, C.4    Vernadakis, A.5
  • 25
    • 0026531691 scopus 로고
    • Intracellular delivery of protein kinase C-alpha or -epsilon isoform-specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells
    • Leli U., Parker P.J., Shea T.B. Intracellular delivery of protein kinase C-alpha or -epsilon isoform-specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells. FEBS Lett. 297:1992;91-94.
    • (1992) FEBS Lett. , vol.297 , pp. 91-94
    • Leli, U.1    Parker, P.J.2    Shea, T.B.3
  • 26
    • 0029940572 scopus 로고    scopus 로고
    • Linking protein kinase C to the cell cycle: Ectopic expression of PKC eta in NIH3T3 cells alters the expression of cyclins and cdk inhibitors and induces adipogenesis
    • Livneh E., Shimon T., Bechor E., Doki Y., Schieren I., Weinstein I.B. Linking protein kinase C to the cell cycle: ectopic expression of PKC eta in NIH3T3 cells alters the expression of cyclins and cdk inhibitors and induces adipogenesis. Oncogene. 12:1996;1545-1555.
    • (1996) Oncogene , vol.12 , pp. 1545-1555
    • Livneh, E.1    Shimon, T.2    Bechor, E.3    Doki, Y.4    Schieren, I.5    Weinstein, I.B.6
  • 27
    • 0029028498 scopus 로고
    • Phorbol esters and PKC signaling regulate proliferation, vimentin cytoskeleton assembly and glutamine synthetase activity of chick embryo cerebrum astrocytes in culture
    • Mangoura D., Sogos V., Dawson G. Phorbol esters and PKC signaling regulate proliferation, vimentin cytoskeleton assembly and glutamine synthetase activity of chick embryo cerebrum astrocytes in culture. Dev. Brain Res. 87:1995;1-11.
    • (1995) Dev. Brain Res. , vol.87 , pp. 1-11
    • Mangoura, D.1    Sogos, V.2    Dawson, G.3
  • 28
    • 0024326484 scopus 로고
    • Early and late passage C6 glial cell growth: Similarities with primary glial cells in culture
    • Mangoura D., Sakellaridis N., Vernadakis A. Early and late passage C6 glial cell growth: similarities with primary glial cells in culture. Neurochem. Res. 14:1989;941-947.
    • (1989) Neurochem. Res. , vol.14 , pp. 941-947
    • Mangoura, D.1    Sakellaridis, N.2    Vernadakis, A.3
  • 29
    • 0026772974 scopus 로고
    • Synthesis of glial fibrillary acidic protein in rat C6 glioma in chemically defined medium: Cyclic AMP-dependent transcriptional and translational regulation
    • Messens J., Slegers H. Synthesis of glial fibrillary acidic protein in rat C6 glioma in chemically defined medium: cyclic AMP-dependent transcriptional and translational regulation. J. Neurochem. 58:1992;2071-2080.
    • (1992) J. Neurochem. , vol.58 , pp. 2071-2080
    • Messens, J.1    Slegers, H.2
  • 30
    • 0027292678 scopus 로고
    • Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta
    • Mischak H., Pierce J.H., Goodnight J., Kazanietz M.G., Blumberg P.M., Mushinski J.F. Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta. J. Biol. Chem. 268:1993;20110-20115.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20110-20115
    • Mischak, H.1    Pierce, J.H.2    Goodnight, J.3    Kazanietz, M.G.4    Blumberg, P.M.5    Mushinski, J.F.6
  • 31
    • 0023036579 scopus 로고
    • Protein kinase C in astrocytes: A determinant of cell morphology
    • Mobley P.L., Scott S.L., Cruz E.G. Protein kinase C in astrocytes: a determinant of cell morphology. Brain Res. 398:1986;366-369.
    • (1986) Brain Res. , vol.398 , pp. 366-369
    • Mobley, P.L.1    Scott, S.L.2    Cruz, E.G.3
  • 32
    • 0029082554 scopus 로고
    • Protein expression of the alpha, gamma, delta and epsilon subspecies of protein kinase C changes as C6 glioma cells become contact inhibited and quiescent in the presence of serum
    • Moreton K., Turner R., Blake N., Paton A., Groome N., Rumsby M. Protein expression of the alpha, gamma, delta and epsilon subspecies of protein kinase C changes as C6 glioma cells become contact inhibited and quiescent in the presence of serum. FEBS Lett. 372:1995;33-38.
    • (1995) FEBS Lett. , vol.372 , pp. 33-38
    • Moreton, K.1    Turner, R.2    Blake, N.3    Paton, A.4    Groome, N.5    Rumsby, M.6
  • 33
    • 0028843905 scopus 로고
    • Mechanisms of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane activation
    • Mosior M., Newton A.C. Mechanisms of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane activation. J. Biol. Chem. 270:1995;25526-25533.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25526-25533
    • Mosior, M.1    Newton, A.C.2
  • 34
    • 0023078917 scopus 로고
    • Phorbol ester stimulate proliferation of astrocytes in primary culture
    • Murphy S., McCabe N., Morrow C., Peace B. Phorbol ester stimulate proliferation of astrocytes in primary culture. Dev. Brain Res. 31:1987;133-135.
    • (1987) Dev. Brain Res. , vol.31 , pp. 133-135
    • Murphy, S.1    McCabe, N.2    Morrow, C.3    Peace, B.4
  • 35
    • 0027180238 scopus 로고
    • Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation
    • Murray N.R., Baumgardner G.P., Burns D.J., Fields A.P. Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. J. Biol. Chem. 268:1993;15847-15853.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15847-15853
    • Murray, N.R.1    Baumgardner, G.P.2    Burns, D.J.3    Fields, A.P.4
  • 36
    • 0026072543 scopus 로고
    • Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: Functional analysis of the PLP promoter
    • Nave K.A., Lemke G. Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: functional analysis of the PLP promoter. J. Neurosci. 11:1991;3060-3069.
    • (1991) J. Neurosci. , vol.11 , pp. 3060-3069
    • Nave, K.A.1    Lemke, G.2
  • 37
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton A.C. Protein kinase C: structure, function, and regulation. J. Biol. Chem. 270:1995;28495-28498.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 38
    • 0026451081 scopus 로고
    • Molecular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y. Molecular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 39
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature. 334:1988;661-665.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 40
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumor promotion
    • Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature. 308:1984;693-698.
    • (1984) Nature , vol.308 , pp. 693-698
    • Nishizuka, Y.1
  • 41
    • 0028168241 scopus 로고
    • A cloning and epsilon-epitope-tagging insert for the expression of polymerase chain reaction-generated cDNA fragments in Escherichia coli and mammalian cells
    • Olah Z., Lehel C., Jakab G., Anderson W.B. A cloning and epsilon-epitope-tagging insert for the expression of polymerase chain reaction-generated cDNA fragments in Escherichia coli and mammalian cells. Anal. Biochem. 221:1994;94-102.
    • (1994) Anal. Biochem. , vol.221 , pp. 94-102
    • Olah, Z.1    Lehel, C.2    Jakab, G.3    Anderson, W.B.4
  • 42
    • 0019224249 scopus 로고
    • Transdifferentiation of C6 glial cells in culture
    • Parker K.K., Norenberg M.D., Vernadakis A. Transdifferentiation of C6 glial cells in culture. Science. 208:1980;179-181.
    • (1980) Science , vol.208 , pp. 179-181
    • Parker, K.K.1    Norenberg, M.D.2    Vernadakis, A.3
  • 43
    • 0027983482 scopus 로고
    • Cyclic AMP decreases the expression of the neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells
    • Segovia J., Lawless G.M., Tillakarante N.J.K., Brenner M., Tobin A.J. Cyclic AMP decreases the expression of the neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells. J. Neurochem. 63:1994;1218-1225.
    • (1994) J. Neurochem. , vol.63 , pp. 1218-1225
    • Segovia, J.1    Lawless, G.M.2    Tillakarante, N.J.K.3    Brenner, M.4    Tobin, A.J.5
  • 44
    • 0024221264 scopus 로고
    • Astrocytes regulate GFAP mRNA levels by cAMP and protein kinase C-dependent mechanisms
    • Shafit-Zagardo B., Kume-Iwaki A., Goldman J.E. Astrocytes regulate GFAP mRNA levels by cAMP and protein kinase C-dependent mechanisms. Glia. 1:1988;346-354.
    • (1988) Glia , vol.1 , pp. 346-354
    • Shafit-Zagardo, B.1    Kume-Iwaki, A.2    Goldman, J.E.3
  • 45
    • 0029384708 scopus 로고
    • The role of intracellular calcium and protein kinase C in endothelin-stimulated proliferation of rat type 1 astrocytes
    • Stanimirovic D.B., Ball R., Mealing G., Morley P., Durkin J.P. The role of intracellular calcium and protein kinase C in endothelin-stimulated proliferation of rat type 1 astrocytes. Glia. 15:1995;119-130.
    • (1995) Glia , vol.15 , pp. 119-130
    • Stanimirovic, D.B.1    Ball, R.2    Mealing, G.3    Morley, P.4    Durkin, J.P.5
  • 46
    • 0028055160 scopus 로고
    • Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH3T3 fibroblasts
    • Szallasi Z., Smith C.B., Pettit G.R., Blumberg P.M. Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH3T3 fibroblasts. J. Biol. Chem. 269:1994;2118-2124.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2118-2124
    • Szallasi, Z.1    Smith, C.B.2    Pettit, G.R.3    Blumberg, P.M.4
  • 47
    • 0024562426 scopus 로고
    • Developmental expression of the glial fibrillary acidic protein mRNA in the central nervous system and in cultured astrocytes
    • Tardy M., Fages C., Riol G., LePrince G., Rataboul P., Charriere-Bertrand C., Nunez J. Developmental expression of the glial fibrillary acidic protein mRNA in the central nervous system and in cultured astrocytes. J. Neurochem. 52:1989;162-167.
    • (1989) J. Neurochem. , vol.52 , pp. 162-167
    • Tardy, M.1    Fages, C.2    Riol, G.3    Leprince, G.4    Rataboul, P.5    Charriere-Bertrand, C.6    Nunez, J.7
  • 49
    • 0026510330 scopus 로고
    • Differential expression of PKC isoforms and PC-12 cell differentiation
    • Wooten M.W. Differential expression of PKC isoforms and PC-12 cell differentiation. Exp. Cell Res. 199:1992;111-119.
    • (1992) Exp. Cell Res. , vol.199 , pp. 111-119
    • Wooten, M.W.1
  • 50
    • 0026695378 scopus 로고
    • Proliferation of human and mouse astrocytes in vitro: Signalling through the protein kinase C pathway
    • Yong V.W. Proliferation of human and mouse astrocytes in vitro: signalling through the protein kinase C pathway. J. Neurol. Sci. 111:1992;92-103.
    • (1992) J. Neurol. Sci. , vol.111 , pp. 92-103
    • Yong, V.W.1
  • 51
    • 0031127084 scopus 로고    scopus 로고
    • Differential expression of Rho family GTP-binding proteins and protein kinase C isozymes during C6 glial cell differentiation
    • Yoshimura S., Sakai H., Nakashima S., Nozawa Y., Shinoda J., Sakai N., Yamada H. Differential expression of Rho family GTP-binding proteins and protein kinase C isozymes during C6 glial cell differentiation. Mol. Brain Res. 45:1997;90-98.
    • (1997) Mol. Brain Res. , vol.45 , pp. 90-98
    • Yoshimura, S.1    Sakai, H.2    Nakashima, S.3    Nozawa, Y.4    Shinoda, J.5    Sakai, N.6    Yamada, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.