Immunohistochemical study on the distribution of phosphorylated extracellular signal-regulated kinase (ERK) in the central nervous system of SOD1G93A transgenic mice

Brain Research

Volumn 1050, Issue 1-2, 2005, Pages 203-209

  Yoon, Hee Chung ^a   Kyeung, Min Joo ^b   Heon, Chang Lim ^b   Mi, Haeng Cho ^b   Kim, Daejin ^a   Won, Bok Lee ^a   Choong, Ik Cha ^b,c  

^a Chung Ang University   (South Korea)

^b Seoul National University   (South Korea)

^c Korea National Institute of Health   (South Korea)

Author keywords

Amyotrophic lateral sclerosis (ALS); Astrocyte; Extracellular signal regulated kinases (ERK); SOD1G93A mutant transgenic mice

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN STEM; CENTRAL GRAY MATTER; CENTRAL NERVOUS SYSTEM; CEREBELLUM; COGNITION; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPINAL CORD; STAINING; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CENTRAL NERVOUS SYSTEM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PHOSPHORYLATION; SUPEROXIDE DISMUTASE;

EID: 21544444452     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.05.060     Document Type: Article

References (26)

1. L.I. Bruijn, M.K. Houseweart, S. Kato, K.L. Anderson, S.D. Anderson, E. Ohama, A.G. Reaume, R.W. Scott, and D.W. Cleveland Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1 Science 281 1998 1851 1854
2. C.I. Cha, J.M. Kim, D.H. Shin, Y.S. Kim, J. Kim, M.E. Gurney, and K.W. Lee Reactive astrocytes express nitric oxide synthase in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation NeuroReport 9 1998 1503 1506
3. C.I. Cha, Y.H. Chung, C.M. Shin, D.H. Shin, Y.S. Kim, M.E. Gurney, and K.W. Lee Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation Brain Res. 853 2000 156 161
4. C.T. Chu, D.J. Levinthal, S.M. Kulich, E.M. Chalovich, and D.B. DeFranco Oxidative neuronal injury. The dark side of ERK1/2 Eur. J. Biochem. 271 2004 2060 2066
5. Y.H. Chung, J.J. Hong, C.M. Shin, K.M. Joo, M.J. Kim, and C.I. Cha Immunohistochemical study on the distribution of homocysteine in the central nervous system of transgenic mice expressing a human Cu/Zn SOD mutation Brain Res. 967 2003 226 234
6. G93A mutant transgenic mice Brain Res. 994 2003 253 259
7. G93A transgenic mice Brain Res. 1016 2004 272 280
8. G93A transgenic mice Brain Res. 1003 2004 199 204
9. D.W. Cleveland, and J.D. Rothstein From Charcot to Lou Gehrig: deciphering selective motor neurone death in ALS Nat. Rev. Neurosci. 2 2001 806 819
10. R.J. Ferrante, L.A. Shinobu, J.B. Schulz, R.T. Matthews, C.E. Thomas, N.W. Kowall, M.E. Gurney, and M.F. Beal Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation Ann. Neurol. 42 1997 326 334
11. I. Ferrer, M. Barrachina, M. Tolnay, M.J. Rey, N. Vidal, M. Carmona, R. Blanco, and B. Puig Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic grain disease Brain Pathol. 13 2003 62 78
12. M.E. Gurney, H. Pu, A.Y. Chiu, M.C. Dal Canto, C.Y. Polchow, D.D. Alexander, J. Caliendo, A. Hentati, Y.W. Kwon, H.X. Deng, W. Chen, P. Zhai, R.L. Sufit, and T. Siddique Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation Science 264 1994 1772 1775
13. H.A. Hanagasi, I.H. Gurvit, N. Ermutlu, G. Kaptanoglu, S. Karamursel, H.A. Idrisoglu, M. Emre, and T. Demiralp Cognitive impairment in amyotrophic lateral sclerosis: evidence from neuropsychological investigation and event-related potentials Brain Res. Cogn. Brain Res. 14 2002 234 244
14. M. Hetman, and A. Gozdz Role of extracellular signal regulated kinases 1 and 2 in neuronal survival Eur. J. Biochem. 271 2004 2050 2055
15. J.S. Marcus, S.L. Karackattu, M.A. Fleegal, and C. Sumners Cytokine-stimulated inducible nitric oxide synthase expression in astroglia: role of Erk mitogen-activated protein kinase and NF-kappaB Glia 41 2003 152 160
16. K. Mielke, and T. Herdegen JNK and p38 stresskinases-degenerative effectors of signal-transduction-cascades in the nervous system Prog. Neurobiol. 61 2000 45 60
17. M. Nagai, M. Aoki, I. Miyoshi, M. Kato, P. Pasinelli, N. Kasai, R.H. Brown Jr., and Y. Itoyama Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease J. Neurosci. 21 2001 9246 9254
18. K.S. Paulus, I. Magnano, M.R. Piras, M.A. Solinas, G. Solinas, G.F. Sau, and I. Aiello Visual and auditory event-related potentials in sporadic amyotrophic lateral sclerosis Clin. Neurophysiol. 113 2002 853 861
19. D.R. Rosen, T. Siddique, D. Patterson, D.A. Figlewicz, P. Sapp, A. Hentati, D. Donaldson, J. Goto, J.P. O'Regan, and H.X. Deng Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Nature 362 1993 59 62
20. L.P. Rowl, and N.A. Shneider Amyotrophic lateral sclerosis N. Engl. J. Med. 344 2001 1688 1700
21. M. Slevin, J. Krupinski, A. Slowik, F. Rubio, A. Szczudlik, and J. Gaffney Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke NeuroReport 11 2000 2759 2764
22. M. Urushitani, and S. Shimohama The role of nitric oxide in amyotrophic lateral sclerosis Amyotroph. Lateral Scler. Other Mot. Neuron Disord. 2 2001 71 81
23. G. Waldemar, S. Vorstrup, T.S. Jensen, A. Johnsen, and G. Boysen Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study J. Neurol. Sci. 107 1992 19 28
24. W. Zang da, Q. Yang, H.X. Wang, G. Egan, E.C. Lopes, and S.S. Cheema Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis Eur. J. Neurosci. 20 2004 1745 1751
25. J.-H. Zhu, S.M. Kulich, T.D. Oury, and C.T. Chu Cytoplasmic aggregates of phosphorylated extracellular signal-regulated kinase in Lewy body diseases Am. J. Pathol. 161 2002 2087 2098
26. X. Zhu, H.G. Lee, A.K. Raina, G. Perry, and M.A. Smith The role of mitogen-activated protein kinase pathways in Alzheimer's disease Neurosignals 11 2002 270 281