Reduction of lipid peroxidation and apoptosis in corneal endothelial cells by vitamin A;Verminderung der lipidperoxidation und der apoptoserate in kornealen endothelzellen durch vitamin A

Ophthalmologe

Volumn 102, Issue 6, 2005, Pages 607-613

  Serbecic, N ^a   Ehmann, A K ^b   Beutelspacher, S C ^c,d  

^a DANUBE HOSPITAL   (Austria)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Antioxidative vitamins; Corneal endothelium; Lipid peroxidation; Oxidative stress

Indexed keywords

CASPASE 3; IRON; MALONALDEHYDE; RETINOIC ACID; RETINOL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORRELATION ANALYSIS; CULTURE MEDIUM; CYTOPLASM; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; QUANTITATIVE ANALYSIS; SUPERNATANT; SUPPLEMENTATION; TISSUE CULTURE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, CORNEAL; IRON; LIPID PEROXIDATION; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; VITAMIN A;

EID: 21544440411     PISSN: 0941293X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00347-004-1143-9     Document Type: Article

References (40)

1. Abudu N, Miller JJ, Attaelmannan M, Levinson SS (2004) Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E. Clin Chim Acta 339:11-25
2. Beckman JS, Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271:C1424-1437
3. Becquet F, Courtois Y, Goureau O (1997) Nitric oxide in the eye: multifaceted roles and diverse outcomes. Surv Ophthalmol 42:71-82
4. Beutelspacher SC, Serbecic N, Tan PH, Mehrabi M, Nielsen P, Yamane Y (2004) Low dose-ethanol modulates toxic effect of iron-overloading in the liver. J Nutr Sci Vitaminol (Tokyo) 50:78-86
5. Bhuyan DK, Master RW, Bhuyan KC (1996) Crosslinking of aminophospholipids in cellular membranes of lens by oxidative stress in vitro. Biochim Biophys Acta 1285:21-28
6. Bohringer D, Reinhard T, Spelsberg H, Sundmacher R (2002) Influencing factors on chronic endothelial cell loss characterised in a homogeneous group of patients. Br J Ophthalmol 86:35-38
7. Boisgerault F, Liu Y, Anosova N, Ehrlich E, Dana MR, Benichou G (2001) Role of CD4+ and CD8+ T cells in allorecognition: lessons from corneal transplantation. J Immunol 167:1891-1899
8. Bourne WM (2001) Cellular changes in transplanted human corneas. Cornea 20:560-569
9. Buettner GR (1993) The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys 300:535-543
10. Campo GM, D'Ascola A, Avenoso A et al. (2003) Glycosaminoglycans reduce oxidative damage induced by copper (Cu(+2)), iron (Fe(+2)) and hydrogen peroxide (H(2)O(2)) in human fibroblast cultures. Glycoconj J 20:133-141
11. Carr AC, McCall MR, Frei B (2000) Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection. ArteriosclerThromb Vasc Biol 20:1716-1723
12. Cejkova J, Stipek S, Crkovska J, Ardan T, Midelfart A (2001) Reactive oxygen species (ROS)-generating oxidases in the normal rabbit cornea and their involvement in the corneal damage evoked by UVB rays. Histol Histopathol 16:523-533
13. Cross AH, Manning PT, Stern MK, Misko TP (1997) Evidence for the production of peroxynitrite in inflammatory CNS demyelination. J Neuroimmunol 80:121-130
14. Esterbauer H, Dieber-Rotheneder M, Striegl G, Waeg G (1991) Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am J Clin Nutr 53:314S-321S
15. Esterbauer H, Puhl H, Dieber-Rotheneder M, Waeg G, Rabl H (1991) Effect of antioxidants on oxidative modification of LDL. Ann Med 23:573-581
16. Ganea E, Harding JJ (2000) Alpha-crystallin protects glucose 6-phosphate dehydrogenase against inactivation by malondialdehyde. Biochim Biophys Acta 1500:49-58
17. Heinecke JW (2002) Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stress. Free Radic Biol Med 32:1090-1101
18. Hodges RE, Sauberlich HE, Canham JE, Wallace DL, Rucker RB, Mejia LA, Mohanram M (1978) Hematopoietic studies in vitamin A deficiency. Am J Clin Nutr 31:876-885
19. Janero DR (2000) Nitric oxide (NO)-related pharmaceuticals: contemporary approaches to therapeutic NO modulation. Free Radic Biol Med 28:1495-1506
20. Jeng BH, Meisler DM, Hollyfield JG, Connor JT, Aulak KS, Stuehr DJ (2002) Nitric oxide generated by corneas in corneal storage media. Cornea 21:410-414
21. Jope RS, Zhang L, Song L (2000) Peroxynitrite modulates the activation of p38 and extracellular regulated kinases in PC12 cells. Arch Biochem Biophys 376:365-370
22. Kaldawy RM, Wagner J, Ching S, Seigel GM (2002) Evidence of apoptotic cell death in keratoconus. Cornea 21:206-209
23. Kim JC, Cheong TB, Park GS, Park MH, Kwon NS, Yoon HY (2002) The role of nitric oxide in ocular surface diseases. Adv Exp Med Biol 506:687-695
24. Kiroycheva M, Ahmed F, Anthony GM, Szabo C, Southan G J, Bank N (2000) Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice. J Am Soc Nephrol 11:1026-1032
25. Kooy NW, Royall JA, Ye YZ, Kelly DR, Beckman JS (1995) Evidence for in vivo peroxynitrite production in human acute lung injury. Am J Respir Crit Care Med 151:1250-1254
26. Kooy NW, Royall JA, Ischiropoulos H (1997) Oxidation of 2′,7′-dichlorofluorescin by peroxynitrite. Free Radic Res 27:245-254
27. Larkin DF (1994) Corneal allograft rejection. Br J Ophthalmol 78:649-652
28. Murphy MP, Packer MA, Scarlett JL, Martin SW (1998) Peroxynitrite: a biologically significant oxidant. Gen Pharmacol 31:179-186
29. O'Connell J, Houston A, Bennett MW, O'Sullivan GC, Shanahan F (2001) Immune privilege or inflammation? Insights into the Fas ligand enigma. Nat Med 7:271-274
30. Ohta K, Kikuchi T, Arai S, Yoshida N, Sato A, Yoshimura N (2003) Protective role of heme oxygenase-1 against endotoxin-induced uveitis in rats. Exp Eye Res 77:665-673
31. Radi R, Peluffo G, Alvarez MN, Naviliat M, Cayota A (2001) Unraveling peroxynitrite formation in biological systems. Free Radic Biol Med 30:463-488
32. Reiter RJ (1995) Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 9:526-533
33. Saleh D, Barnes PJ, Giaid A (1997) Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 155:1763-1769
34. Sobottka Ventura AC, Engelmann K, Dahinden C, Bohnke M (1997) Endotoxins modulate the autocrine function of organ cultured donor corneas and increase the incidence of endothelial cell death. Br J Ophthalmol 81:1093-1098
35. Takahashi A, Masuda A, Sun M, Centonze VE, Herman B (2004) Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm). Brain Res Bull 62:497-504
36. The Collaborative Corneal Transplantation Studies Research Group (1992) The collaborative corneal transplantation studies (CCTS). Effectiveness of histocompatibility matching in high-risk corneal transplantation. Arch Ophthalmol 110:1392-1403
37. Welch KD, Davis TZ, Van Eden ME, Aust SD (2002) Deleterious iron-mediated oxidation of biomolecules. Free Radic Biol Med 32:577-583
38. Wyllie AH, Kerr JF, Currie AR (1980) Cell death: the significance of apoptosis. Int Rev Cytol 68:251-306
39. Yilmaz G, Sizmaz S, Yilmaz ED, Duman S, Aydin P (2002) Aqueous humor nitric oxide levels in patients with Behcet disease. Retina 22:330-335
40. Zhou XJ, Laszik Z, Wang XQ, Silva FG, Vaziri ND (2000) Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis. Lab Invest 80:1905-1914