Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells

Circulation

Volumn 98, Issue 1, 1998, Pages 1-5

  Villanueva, Flordeliza S ^a,e   Jankowski, Ron J ^b   Klibanov, Sasha ^d   Pina, Maris L ^a   Alber, Sean M ^c   Watkins, Simon C ^c   Brandenburger, Gary H ^d   Wagner, William R ^b  

^a Division of Cardiology   (United States)

^b Division of Cardiothoracic Surgery   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d MALLINCKRODT PHARMACEUTICALS   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cell adhesion molecules; Cells; Endothelium; Microspheres

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; BUTANE; ECHO CONTRAST MEDIUM; FLUOROCARBON; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MICROSPHERE; MONOCLONAL ANTIBODY; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTERY WALL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL ACTIVATION; CELL ADHESION; CONTROLLED STUDY; CORONARY ARTERY; DRUG TARGETING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SHEAR RATE; ULTRASOUND;

EID: 0032493267     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.98.1.1     Document Type: Article

References (11)

1. Libby P, Hansson GK. Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Investigation. 1991;64:5-15.
2. Cybulsky MI, Gimbrone MA. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991;251:788-791.
3. Kaul S. Myocardial contrast echocardiography: 15 years of research and development. Circulation. 1997;96:3745-3760.
4. Villanueva FS, Jankowski RJ, Manaugh C, Wagner WR. Albumin microbubble adherence to human coronary endothelium: implications for assessment of endothelial function using myocardial contrast echocardiography. J Am Coll Cardiol. 1997;30:689-693.
5. Staros JV, Wright RW, Swingle DM. Enhancement of N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions. Anal Biochem. 1986;156:220-222.
6. Van de Stolpe A, van der Saag PT. Intercellular adhesion molecule-1. J Mol Med. 1996;74:13-33.
7. Lanza GM, Wallace KD, Scott MJ, Cacheris WP, Abendschein DR, Christy DH, Sharkey AM, Miller JG, Gaffney PJ, Wickline SA. A novel site-targeted ultrasound contrast agent with broad biomedical application. Circulation. 1997;95:3334-3340.
8. McCreery TP, Sweitzer RH, Shen D, Wu G, Unger EC. Ultrasound detection of arterial and venous thrombosis with MRX408: a novel ultrasound contrast agent. Circulation. 1997;96(suppl I):I-213. Abstract.
9. Demos SM, Onyuksel H, Gilbert J, Sanford RI, Kane B, Jungblut P, Pinto JV, McPherson DD, Klegerman ME. In vitro targeting of antibodyconjugated echogenic liposomes for site-specific ultrasonic image enhancement. J Pharm Sci. 1997;86:167-171.
10. Bloemen PGM, Henricks PAJ, van Bloois L, van den Tweel MC, Bloem AC, Nijkamp FP, Crommelin DJA, Storm G. Adhesion molecules: a new target for immunoliposome-mediated drug delivery. FEBS Lett. 1995;57:140-144.
11. Klibanov AL, Hughes MS, Marsh JN, Hall CX, Miller JG, Wible JH, Brandenburger GH. Targeting of ultrasound contrast material: an in vitro feasibility study. Acta Radiol. 1997;38:113-120.