Propriospinal circuitry underlying interlimb coordination in mammalian quadrupedal locomotion

Journal of Neuroscience

Volumn 25, Issue 25, 2005, Pages 6025-6035

  Juvin, Laurent ^a   Simmers, John ^a   Morin, Didier ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Forelimb; Hindlimb; In vitro; Locomotion; Neuronal network interactions; Newborn rat; Spinal cord

Indexed keywords

DOPAMINE; N METHYL DEXTRO ASPARTIC ACID; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; CELL INTERACTION; CERVICAL SPINE; CONTROLLED STUDY; ELECTROMYOGRAPHY; FEMALE; FORELIMB; GAIT; HINDLIMB; LIMB MOVEMENT; LOCOMOTION; MAMMAL; MOTONEURON; MOTOR COORDINATION; NERVE CELL NETWORK; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROPRIOCEPTION; RAT; SPINAL CORD STIMULATION; SYNAPTIC INHIBITION; WALKING;

ANIMALS; ANIMALS, NEWBORN; EXTREMITIES; LOCOMOTION; MAMMALS; MOTOR ACTIVITY; PROPRIOCEPTION; RATS; SEROTONIN; SPINAL CORD; SYNAPTIC TRANSMISSION;

EID: 21344465418     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0696-05.2005     Document Type: Article

References (47)

1. Ballion B, Morin D, Viala D (2001) Forelimb locomotor generators and quadrupedal locomotion in the neonatal rat. Eur J Neurosci 14:1727-1738.
2. Barrière G, Meilen N, Cazalets JR (2004) Neuromodulation of the locomotor network by dopamine in the isolated spinal cord of newborn rat. Eur J Neurosci 19:1325-1335.
3. Bekoff A, Lau B (1980) Interlimb coordination in 20-day-old rat fetuses. J Exp Zool 214:173-175.
4. Bekoff A, Trainer W (1979) The development of inter-limb co-ordination during swimming in postnatal rats. J Exp Biol 83:1-11.
5. Birinyi A, Viszokay K, Weber I, Kiehn O, Antal M (2003) Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats. J Comp Neurol 461:429-440.
6. Bracci E, Ballerini L, Nistri A ( 1996) Localization of rhythmogenic networks responsible for spontaneous bursts induced by strychnine and bicuculline in the rat isolated spinal cord. J Neurosci 16:7063-7076.
7. Brocard F, Vinay L, Clarac F ( 1999) Development of hindlimb postural control during the first postnatal week in the rat. Dev Brain Res 117:81-89.
8. Butt SJ, Kiehn O (2003) Functional identification of interneurons responsible for left-right coordination of hindlimbs in mammals. Neuron 38:953-963.
9. Butt SJ, Lebret JM, Kiehn O (2002) Organization of left-right coordination in the mammalian locomotor network. Brain Res Brain Res Rev 40:107-117.
10. Cazalets JR, Bertrand S (2000) Ubiquity of motor networks in the spinal cord of vertebrates. Brain Res Bull 53:627-634.
11. Cazalets JR, Sqalli-Houssaini Y, Clarac F (1992) Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat. J Physiol (Lond) 455:187-204.
12. Cazalets JR, Borde M, Clarac F (1995) Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat. J Neurosci 15:4943-4951.
13. Cowley KC, Schmidt BJ (1995) Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. J Neurophysiol 74:1109-1117.
14. Cowley KC, Schmidt BJ (1997) Regional distribution of the locomotor pattern-generating network in the neonatal rat spinal cord. J Neurophysiol 77:247-259.
15. Cowley KC, Zaporozhets E, Schmidt BJ (2003) Influence of the thoracolumbar region on locomotor and non-locomotor rhythm generation in vitro neonatal rat spinal cord. Soc Neurosci Abstr 29:277.10.
16. Delvolvé I, Bern T, Cabelguen J-M (1997) Epaxial and limb muscle activity during swimming and terrestrial stepping in the adult newt, Pleuodeles waltl. J Neurophysiol 78:638-650.
17. Dietz V (2002) Do human bipeds use quadrupedal coordination? Trends Neurosci 25:462-467.
18. Dietz V, Nakazawa K, Wirz M, Erni T (1999) Level of spinal cord lesion determines locomotor activity in spinal man. Exp Brain Res 128:405-409.
19. Eide AL, Glover J, Kjaerulff O, Kiehn O (1999) Characterization of commissural interneurons in the lumbar region of the neonatal rat spinal cord. J Comp Neurol 403:332-345.
20. English AW (1979) Interlimb coordination during stepping in the cat: an electromyographic analysis. J Europhysiol 42:638-650.
21. English AW (1989) Interlimb coordination during locomotion. Am Zool 29:255-266.
22. English AW, Tigges J, Lennard PR (1985) Anatomical organization of long ascending propriospinal neurons in the cat spinal cord. J Comp Neurol 240:349-358.
23. Gramsbergen A, Geisler HC, Taekema H, van Eykern LA (1999) The activation of back muscles during locomotion in the developing rat. Brain Res Dev Brain Res 112:217-228.
24. Grillner S (1981) Control of locomotion in bipeds, tetrapods and fish. In: Handbook of physiology, Sec 2. The nervous system (Brookhardt JM, Mountcastle VB, eds), pp 1179-1236. Bethesda, MD: American Physiological Society.
25. Hildebrand M (1961) Further studies on the locomotion of the cheetah. J Mammal 42:84-89.
26. Ho SM (1997) Rhythmic motor activity and interlimb co-ordination in the developing pouch young of a wallaby (Macropus eugenii). J Physiol (Lond) 501:623-636.
27. Jamon M, Clarac F (1998) Early walking in the neonatal rat: a kinematic study. Behav Neurosci 112:1218-1228.
28. Juvin L, Nargeot R, Morin D (2003) Central and sensory mechanisms underlying intersegmental coordination in quadrupedal fictive locomotion. Soc Neurosci Abstr 29:277.18.
29. Kiehn O, Butt SJ (2003) Physiological, anatomical and genetic identification of CPG neurons in the developing mammalian spinal cord. Prog Neurobiol 70:347-361.
30. Kjaerulff O, Kiehn O (1996) Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study. J Neurosci 16:5777-5794.
31. Koehler WJ, Schomburg ED, Stephens H (1984) Phasic modulation of trunk muscles afferents during fictive spinal locomotion in cats. J Physiol (Lond) 353:187-197.
32. Kremer E, Lev-Tov A (1997) Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J Neurophysiol 77:1155-1170.
33. Marder E, Calabrese RL (1996) Principles of rhythmic motor pattern generation. Physiol Rev 76:687-717.
34. Matsushima T, Grillner S (1992) Neural mechanisms of intersegmental coordination in lamprey: local excitability changes modify the phase coupling along the spinal cord. J Neurophysiol 67:373-388.
35. McEwen ML, Van Hartesveldt C, Stehouwer DJ (1997) L-DOPA and quipazine elicit air-stepping in neonatal rats with spinal cord transections. Behav Neurosci 111:825-833.
36. McKenna JE, Prusky GT, Whishaw IQ (2000) Cervical motoneuron topography reflects the proximodistal organization of muscles and movements of the rat forelimb: a retrograde carbocyanine dye analysis. J Comp Neurol 419:286-296.
37. Nathan PW, Smith M, Deacon P (1996) Vestibulospinal, reticulospinal and descending propriospinal nerve fibres in man. Brain 119:1809-1833.
38. Navarrete R, Slawińska U, Vrbová G (2002) Electromyographic activity patterns of ankle flexor and extensor muscles during spontaneous and L-DOPA-induced locomotion in freely moving neonatal rats. Exp Neurol 173:256-265.
39. Nishimaru H, Kudo N (2000) Formation of the central pattern generator for locomotion in the rat and mouse. Brain Res Bull 53:661-669.
40. Orlovsky GN, Deliagina TG, Grillner S (1999) Quadrupedal locomotion in mammals. In: Neuronal control of locomotion: from mollusc to man (Orlovsky GN, Deliagina, TG, Grillner S, eds), pp 154-246. New York: Oxford UP.
41. Rossignol S (1996) Neural control of stereotypic limb movements. In: Handbook of physiology, Sec 12. Exercise: regulation and integration of multiple movements (Rowell RB, Shepherd JT, eds), pp 173-216. Bethesda, MD: American Physiological Society.
42. Stein PSG, Grillner S, Selverston AI, Stuart DG (1997) Neurons, networks, and motor behavior. Cambridge, MA: MIT.
43. Stokke MF, Nissen UV, Glover JC, Kiehn O (2002) Projection patterns of commissural interneurons in the lumbar spinal cord of the neonatal rat. J Comp Neurol 446:349-359.
44. Taub E, Uswatte G, Elbert T (2002) New treatments in neurorehabilitation founded on basic research. Nat Rev Neurosci 3:228-236.
45. Tunstall MJ, Roberts AA (1994) Longitudinal gradient of synaptic drive in the spinal cord of Xenopus embryos and its role in co-ordination of swimming. J Physiol (Lond) 474:393-405.
46. Viala D, Vidal C (1978) Evidence for distinct spinal locomotion generators supplying respectively fore- and hindlimbs in the rabbit. Brain Res 155:182-186.
47. Wannier T, Bastiaanse C, Colombo G, Dietz V (2001) Arm to leg coordination in humans during walking, creeping and swimming activities. Exp Brain Res 141:375-379.