Forelimb locomotor generators and quadrupedal locomotion in the neonatal rat

European Journal of Neuroscience

Volumn 14, Issue 10, 2001, Pages 1727-1738

  Ballion, Bérangère ^a   Morin, Didier ^a   Viala, Denise ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Fictive locomotion; Forelimb; Hindlimb; Rhythm generator interactions; Spinal cord

Indexed keywords

KAINIC ACID; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID; SEROTONIN;

ARTICLE; CEREBROSPINAL FLUID; CERVICAL SPINE; CONTROLLED STUDY; FEMALE; FORELIMB; LOCOMOTION; LUMBAR SPINAL CORD; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD TRANSSECTION; THORACIC SPINAL CORD;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; BRAIN STEM; CERVICAL VERTEBRAE; EFFERENT PATHWAYS; EXCITATORY AMINO ACID AGONISTS; FORELIMB; LOCOMOTION; MAGNESIUM; MOTOR NEURONS; NERVE NET; PERIODICITY; POTASSIUM DEFICIENCY; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SPINAL CORD; SPINAL NERVE ROOTS; SYNAPTIC TRANSMISSION;

EID: 0035784399     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01794.x     Document Type: Article

References (55)

1. Altman, J. & Sudarshan, K. (1975) Postnatal development of locomotion in the laboratory rat. Anim. Behav., 23, 896-920.
2. Arshavsky, Y.I., Orlovky, G.N., Panchin, Y.V., Roberts, A. & Soffe, S.R. (1993) Neuronal control of swimming locomotion: Analysis of pteropod mollusc Clione and embryos of amphibian Xenopus. Trends Neurosci., 16, 227-233.
3. Beato, M., Bracci, E. & Nistri, A. (1997) Contribution of NMDA and non-NMDA glutamate receptors to locomotor pattern generation in the neonatal rat spinal cord. Proc. R. Soc. Lond. B. Biol. Sci., 264, 877-884.
4. Bonnot, A. & Morin, D. (1998) Hemisegmental localisation of rhythmic networks in the lumbosacral spinal cord of neonate mouse. Brain Res., 793, 136-148.
5. Bonnot, A., Morin, D. & Viala, D. (1998) Genesis of spontaneous rhythmic motor patterns in the lumbosacral spinal cord of neonate mouse. Dev. Brain Res., 108, 89-99.
6. Bracci, E., Ballerini, L. & Nistri, A. (1996) Localisation of rhythmogenic networks responsible for spontaneous bursts induced by strychnine and bicuculline in the rat isolated spinal cord. J. Neurosci., 16, 7063-7076.
7. Bracci, E., Beato, M. & Nistri, A. (1998) Extracellular K+ induces locomotor-like patterns in the rat spinal cord in vitro: Comparison with NMDA or 5-HT induced activity. J. Neurophysiol., 79, 2643-2652.
8. Brocard, F., Vinay, L. & Clarac, F. (1999) Development of hindlimb postural control during the first postnatal week in the rat. Dev. Brain Res., 117, 81-89.
9. Brown, T.G. (1911) The intrinsic factors in the act of progression in the mammal. Proc. R. Soc. B., 84, 308-319.
10. Cazalets, J.R. & Bertrand, S. (2000) Coupling between lumbar and sacral motor networks in the neonatal rat spinal cord. Eur. J. Neurosci., 12, 2993-3002.
11. Cazalets, J.R., Borde, M. & Clarac, F. (1995) Localisation and organisation of the central pattern generator for hindlimb locomotion in new-born rats. J. Neurosci., 15, 4943-4951.
12. Cazalets, J.R., Borde, M. & Clarac, F. (1996) The synaptic drive from the spinal network to motoneurons in new-born rats. J. Neurosci., 16, 298-306.
13. Cazalets, J.R., Menard, I., Crémieux, J. & Clarac, F. (1990) Variability as a characteristic of immature motor systems: An electromyographic study of swimming in the new-born rat. Behav. Brain Res., 40, 215-225.
14. Cazalets, J.R., Sqalli-Houssaini, Y. & Clarac, F. (1992) Activation of the central pattern generators for locomotion by serotonin and excitatory amino-acids in neonatal rat. J. Physiol. (Lond.), 455, 187-204.
15. Clarac, F., Vinay, L., Cazalets, J.R., Fady, J.C. & Jamon, M. (1998) Role of gravity in the development of posture and locomotion in the neonatal rat. Brain Res. Rev., 28, 35-43.
16. Cohen, A.H. & Wallen, P. (1980) The neuronal correlate of locomotion in fish. Exp. Brain Res., 41, 11-18.
17. Cowley, K.C. & Schmidt, B.J. (1997) Regional distribution of the locomotor pattern-generating network in the neonatal rat spinal cord. J. Neurophysiol., 77, 247-259.
18. Delvolvé, I., Branchereau, P., Dubuc, R. & Cabelguen, J.M. (1999) Fictive rhythmic motor patterns induced by NMDA in an in vitro brainstem-spinal cord preparation from an adult urodele. J. Neurophysiol., 82, 1074-1077.
19. Forssberg, H., Grillner, S. & Halbertsma, J. (1980) The locomotion of the low spinal cat. I - Coordination within a hindlimb. Acta Physiol. Scand., 108, 269-281.
20. Grillner, S., Deliagina, T., Ekeberg, O., El Manira, A., Hill, R.H., Lansner, A., Orlovsky, G.N. & Wallen, P. (1995) Neural networks that coordinate locomotion and body orientation in lamprey. Trends Neurosci., 18, 270-279.
21. Grillner, S. & Zangger, P. (1979) On the central generation of locomotion in the low spinal cat. Exp. Brain Res., 34, 241-261.
22. Ho, S.M. (1997) Rhythmic motor activity and interlimb coordination in the developing pouch young of a wallaby (Macropus eugenii). J. Physiol. (Lond.), 501, 623-636.
23. Ho, S. & O'Donovan, M.J. (1993) Regionalization and intersegmental coordination of rhythm-generating networks in the spinal cord of the chick embryo. J. Neurosci., 13, 1354-1371.
24. Iwahara, I., Van Hartesveldt, C., Garcia-Rill, E. & Skinner, R.D. (1991) L-DOPA-induced air stepping in decerebrate developing rats. Dev. Brain Res., 58, 257-264.
25. Kiehn, O. & Kjaerulff, O. (1996) Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat. J. Neurophysiol., 75, 1472-1482.
26. Kjaerulff, O., Barajon, I. & Kiehn, O. (1994) Sulphorhodamine-labelled cells in the neonatal rat spinal cord following chemically induced locomotor activity in vitro. J. Physiol. (Lond.), 478, 265-273.
27. Kjaerulff, O. & Kiehn, O. (1996) Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: A lesion study. J. Neurosci., 16, 5777-5794.
28. Kremer, E. & Lev-Tov, A. (1997) Localisation of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organisation of its transverse coupling system. J. Neurophysiol., 77, 1155-1170.
29. Kudo, N. & Yamada, T. (1987) N-methyl-D,L-aspartate-induced locomotor activity in a spinal cord - Hindlimb muscles preparation of the new-born rat studied in vitro. Neurosci. Lett., 75, 43-48.
30. Lev-Tov, A., Delvolve, I. & Kremer, E. (2000) Sacrocaudal afferents induce rhythmic efferent bursting in isolated spinal cords of neonatal rats. J. Neurophysiol., 83, 888-894.
31. MacCrea, A.E., Stehouwer, D.J. & Van Hartesveldt, C. (1994) L-DOPA-induced air-stepping in preweanling rats. I. Effects of dose and age. Dev. Brain Res., 82, 136-142.
32. Mayer, M.L. & Westbrook, G.L. (1987) The physiology of excitatory aminoacids in the vertebrate central nervous system. Prog. Neurobiol., 28, 197-276.
33. 2+ of NMDA responses in spinal cord neurons. Nature, 309, 261-263.
34. McKenna, J.E., Prusky, G.T. & Whishaw, I.Q. (2000) Cervical motoneuron topography reflects the proximodistal organisation of muscles and movements of the rat forelimb: A retrograde carbocyanine dye analysis. J. Comp. Neurol., 419, 286-296.
35. Morin, D., Bonnot, A., Ballion, B. & Viala, D. (2000) Alpha1-adrenergic receptor-induced slow rhythmicity in nonrespiratory cervical motoneurons of neonatal rat spinal cord. Eur J. Neurosci., 12, 2950-2966.
36. Nadim, F., Manor, Y., Nusbaum, M.P. & Marder, E. (1998) Frequency regulation of a slow rhythm by a fast periodic input. J. Neurosci., 18, 5053-5067.
37. Nowak, L., Bregestovski, P., Ascher, P., Herbet, A. & Prochianz, A. (1984) Magnesium gates glutamate-activated channels in mouse central neurons. Nature, 307, 462-465.
38. Ryan, J.M., Cushman, J. & Baier, C. (1997) Organisation of forelimb motoneuron pools in the two bat species (Eptesicus fuscus and Myotis lucifugus). Acta Anat., 158, 121-129.
39. Ryan, J.M., Cushman, J., Jordan, B., Samuels, A., Frazer, H. & Baier, C. (1998) Topographic position of forelimb motoneuron pools is conserved in vertebrate evolution. Brain Behav. Evol., 51, 90-99.
40. Schotland, J.L. & Grillner, S. (1993) Effects of serotonin on fictive locomotion co-ordinated by a neural network deprived of NMDA receptor-mediated cellular properties. Exp. Brain Res., 93, 391-398.
41. Smith, J.C. & Feldman, J.L. (1987) In vitro brainstem-spinal cord preparations for study of motor systems for mammalian respiration and locomotion. J. Neurosci. Meth., 21, 321-333.
42. Smith, J.C., Greer, J.J., Guosong, L. & Feldman, J.L. (1990) Neural mechanisms generating respiratory pattern in mammalian brainstem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity. J. Neurophysiol., 64, 1149-1169.
43. Sqalli-Houssaini, Y., Cazalets, J.R. & Clarac, F. (1993) Oscillatory properties of the central pattern generator for locomotion in neonatal rats. J. Neurophysiol., 70, 803-813.
44. Stehouwer, D.J. & Farel, P.B. (1980) Central and peripheral control of swimming in anuran larvae. Brain Res., 195, 323-335.
45. Stehouwer, D.J., McCrea, A.E. & Van Hartesveldt, C. (1994) L-DOPA-induced air-stepping in preweanling rats. II. Kinematic analyses. Dev. Brain Res., 82, 143-151.
46. Stephens, N. & Holder, N. (1985) A horseradish peroxidase study of motoneuron pools of the forelimb and hindlimb musculature of the axolotl. Proc. R. Soc. Lond. B. Biol. Sci., 224, 325-339.
47. Syed, N. & Winlow, W. (1991) Coordination of locomotor and cardiorespiratory networks of Lymnaea stagnalis by a pair of identified interneurones. J. Exp. Biol., 158, 37-62.
48. Takahashi, T. & Berger, A.J. (1990) Direct excitation of rat spinal motoneurons by serotonin. J. Physiol. (Lond.), 423, 63-76.
49. Van Hartesveldt, C., Sickles, A.E., Porter, J.D. & Stehouwer, D.J. (1991) L-DOPA-induced air-stepping in developing rats. Dev. Brain Res., 58, 251-255.
50. Van Mier, P., Armstrong, J. & Roberts, A. (1989) Development of early swimming in Xenopus laevis embryos: Myotomal musculature, its innervation and activation. Neuroscience, 32, 113-126.
51. Viala, D. & Buser, P. (1971) Methods of obtaining locomotor rhythms in the spinal rabbit by pharmacological treatments (DOPA, 5-HTP, D-amphetamine). Brain Res., 35, 151-165.
52. Viala, D. & Freton, E. (1983) Evidence for respiratory and locomotor pattern generator in the rabbit cervico-thoracic cord and for their interactions. Exp. Brain Res., 49, 247-256.
53. Viala, D., Persegol, L. & Palisses, R. (1987) Relationship between phrenic and hindlimb extensor activities during fictive locomotion. Neurosci. Lett., 74, 49-52.
54. Wheatley, M. & Stein, R.B. (1992) An in vitro preparation of the mudpuppy for simultaneous intracellular and electromyographic recording during locomotion. J. Neurosci. Meth., 42, 129-137.
55. Yamaguchi, T. (1992) Activity of cervical neurons during forelimb fictive locomotion in decerebrate cats. Jpn. J. Physiol., 42, 501-514.